The role of response elements organization in transcription factor selectivity: The ifn-β enhanceosome example

PLoS Computational Biology

Volumn 7, Issue 6, 2011, Pages

  Pan, Yongping ^a   Nussinov, Ruth ^a,b  

^a SAIC FREDERICK INC   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BIOINFORMATICS; DNA; MOLECULAR DYNAMICS; TRANSCRIPTION;

CELLULARS; COOPERATIVITY; CRYSTALS STRUCTURES; DNA RESPONSE ELEMENT; DYNAMICS SIMULATION; ELEMENT SPECIFIC; MODELLING SYSTEMS; PROTEIN-PROTEIN INTERACTIONS; RESPONSE ELEMENTS; SPECIFIC BINDING;

TRANSCRIPTION FACTORS;

ACTIVATING TRANSCRIPTION FACTOR 2; ARGININE; BETA INTERFERON; ENHANCEOSOME; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; PROTEIN C JUN; PROTEIN P50; SPACER DNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA;

ARTICLE; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA CONFORMATION; DNA HELIX; DNA RESPONSIVE ELEMENT; ENHANCER REGION; MOLECULAR DYNAMICS; PROCESS OPTIMIZATION; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; BIOLOGICAL MODEL; BIOLOGY; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING;

BASE SEQUENCE; BINDING SITES; COMPUTATIONAL BIOLOGY; HUMANS; INTERFERON-BETA; MODELS, GENETIC; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RESPONSE ELEMENTS; TRANSCRIPTION FACTORS;

EID: 79959856940     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002077     Document Type: Article

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