The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome

Molecular Cell

Volumn 1, Issue 1, 1997, Pages 119-129

  Kim, Tae Kook ^a   Maniatis, Tom ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; ATF2 PROTEIN, HUMAN; BETA INTERFERON; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA BINDING PROTEIN; HIGH MOBILITY GROUP A1A PROTEIN; HIGH MOBILITY GROUP PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; IRF1 PROTEIN, HUMAN; LEUCINE ZIPPER PROTEIN; PHOSPHOPROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR II; TRANSCRIPTION FACTOR IIA; TRANSCRIPTION FACTOR IIB; TRANSCRIPTION FACTOR IID; TRANSCRIPTION FACTOR RELA; TUMOR PROTEIN;

ARTICLE; BINDING SITE; CHEMISTRY; DRUG EFFECT; DRUG POTENTIATION; ENHANCER REGION; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETICS; HELA CELL; HUMAN; METABOLISM; PHYSIOLOGY; PROMOTER REGION; TRANSACTIVATION;

ACTIVATING TRANSCRIPTION FACTOR 2; BINDING SITES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA-BINDING PROTEINS; DRUG SYNERGISM; ENHANCER ELEMENTS (GENETICS); ESCHERICHIA COLI; GENE EXPRESSION REGULATION; HELA CELLS; HIGH MOBILITY GROUP PROTEINS; HMGA1A PROTEIN; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON-BETA; LEUCINE ZIPPERS; NEOPLASM PROTEINS; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR TFIIA; TRANSCRIPTION FACTOR TFIIB; TRANSCRIPTION FACTOR TFIID; TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, TFII;

EID: 0031310825     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80013-1     Document Type: Article

References (44)

1. Arias, J., Alberts, A.S., Brindle, P., Claret, F.X., Smeal, T., Karin, M., Feramisco, J., and Montminy, M. (1994). Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature 370, 226-229.
2. Burley, S.K., and Roeder, R.G. (1996). Biochemistry and structural biology of transcription factor MD (TFIID). Annu. Rev. Biochem. 65, 769-799.
3. Bustin, M., and Reeves, R. (1996). High-mobility-group proteins: architectural components that facilitate chromatin function. Prog. Nucleic Acid Res. 54, 35-100.
4. Carey, M., Lin, Y.S., Green, M.R., and Ptashne, M. (1990). A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature 345, 361-364.
5. Chi, T., Lieberman, P., Ellwood, K.,and Carey, M. (1995). A general mechanism for transcriptional synergy by eukaryotic activators. Nature 377, 254-257.
6. Chiang, C.M., Ge, H., Wang, Z., Hoffmann, A., and Roeder, R.G. (1993). Unique TATA-binding protein-containing complexes and co-factors involved in transcription by RNA polymerases II and III. EMBO J. 12, 2749-2762.
7. Dignam, J.D., Lebovitz, R.M., and Roeder, R.G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11, 1475-1489.
8. Driever, W., and Nüsslein-Volhard, C. (1989). The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo. Nature 337, 138-143.
9. Du, W., and Maniatis, T. (1994). The high mobility group protein HMG I(Y) can stimulate or inhibit DNA binding of distinct transcription factor ATF2 isoforms. Proc. Natl. Acad. Sci. USA 91, 11318-11322.
10. Du, W., Thanos, D., and Maniatis, T. (1993). Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell 74, 887-898.
11. Falvo, J.V., Thanos, D., and Maniatis, T. (1995). Reversal of intrinsic DNA bends in the IFNβ gene enhancer by transcription factors and the architectural protein HMG I(Y). Cell 83, 1101-1111.
12. Gerritsen, M.E., Williams, A.J., Neish, A.S., Moore, S., Shi, Y., and Collins, T. (1997). CREB-binding protein/p300 are transcriptional coactivators of p65. Proc. Natl. Acad. Sci. USA 94, 2927-2932.
13. Grosschedl, R. (1995). Higher-order nucleoprotein complexes in transcription: analogies with site-specific recombination. Curr.Opin. Cell Biol. 7, 362-370.
14. Hai, T., Horikoshi, M., Roeder, R.G., and Green, M.R. (1988). Analysis of the role of the transcription factor ATF in the assembly of a functional preinitiation complex. Cell 54, 1043-1051.
15. Hawley, D.K., and Roeder, R.G. (1985). Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. J. Biol. Chem. 260, 8163-8172.
16. Johnston, D.S., and Nüsslein-Volhard, C. (1992). The origin of pattern and polarity in the Drosophila embryo. Cell 68, 201-219.
17. Kaiser, K., and Meisterernst, M. (1996).The human general co-factor. Trends Biochem. Sci. 21, 342-345.
18. Kim, T.K., and Roeder, R.G. (1994). Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation. Proc. Natl. Acad. Sci. USA 91, 4170-4174.
19. Kim, T.K., and Roeder, R.G. (1997). Critical role of the second stirrup region of the TATA-binding protein for transcriptional activation both in yeast and human. J. Biol. Chem. 272, 7540-7545.
20. Kim, T.K., Hashimoto, S., Kelleher, R.J., Flanagan, P.M., Kornberg, R.D., Horikoshi, M., and Roeder, R.G. (1994). Effects of activation-defective TBP mutations on transcription initiation in yeast. Nature 369, 252-255.
21. Kim, T.K., Zhao, Y., Ge, H., Bernstein, R., and Roeder, R.G. (1995). TATA-binding protein residues implicated in a functional interplay between negative cofactor NC2 (Dr1) and general factors TFIIA and TFIIB. J. Biol. Chem. 270, 10976-10981.
22. Koleske, A.J., and Young, R.A. (1995). The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem. Sci. 20, 113-116.
23. Laybourn, P.J., and Kadonaga, J.T. (1992). Threshold phenomena and long-distance activation of transcription by RNA polymerase II. Science 257, 1682-1685.
24. Lin, Y.S., Carey, M., Ptashne, M., and Green, M. R. (1990). How different eukaryotic transcriptional activators can cooperate promiscuously. Nature 345, 359-361.
25. Maher, J.F., and Nathans, D. (1996). Multivalent DNA-binding properties of the HMG-I proteins. Proc. Natl. Acad. Sci. USA 93, 6716-6720.
26. Maniatis, T., Goodbourn, S., and Fischer, J.A. (1987). Regulation of inducible and tissue-specific gene expression. Science 236, 1237-1245.
27. Maniatis, T., Whittemore, L.-A., Du, W., Fan, C.-M., Keller, A.D., Palombella, V.J., and Thanos, D. (1992). Positive and negative control of human interferon-β gene expression. In Transcriptional Regulation, S. L. McKnight and K. R. Yamamoto, eds.(Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press), pp. 1193-1220.
28. Matsuyama, T., Kimura, T., Kitagawa, M., Pfeffer, K., Kawakami, T., Watanabe, N., Kundig, T., Amakawa, R., Kishihara, K., Wakeham, A., et al. (1993). Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell 75, 83-97.
29. Mayall, T.P., Sheridan, P.L., Montminy, M.R., and Jones, K.A. (1997). Distinct roles for P-CREB and LEF-1 in TCRα enhancer assembly and activation on chromatin templates in vitro. Genes Dev. 11, 887-899.
30. McKnight, S.L., and Yamamoto, K.R. (1992). Transcriptional Regulation (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
31. Meisterernst, M., Roy, A.L., Lieu, H.M., and Roeder, R.G. (1991). Activation of class II gene transcription by regulatory factors is potentiated by a novel activity. Cell 66, 981-993.
32. Nakajima, T., Uchida, C., Anderson, S.F., Parvin, J.D., and Montminy, M. (1997). Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors. Genes Dev. 11, 738-747.
33. Neish, A.S., Read, M.A., Thanos, D., Pine, R., Maniatis, T., and Collins, T. (1995). Endothelial interferon regulatory factor 1 cooperates with NF-κB as a transcriptional activator of vascular cell adhesion molecule 1. Mol. Cell. Biol. 15, 2558-2569.
34. Orphanides, G., Lagrange, T., and Reinberg, D. (1996). The general transcription factors of RNA polymerase II. Genes Dev. 10, 2657-2683.
35. Perkins, N.D., Felzien, L.K., Betts, J.C., Leung, K., Beach, D., and Nabel, G. (1997). Regulation of NF-κB by cyclin-dependent kinases associated with p300 coactivator. Science 275, 523-527.
36. Ptashne, M., and Gann, A. (1997). Transcriptional activation by recruitment in bacteria and yeast. Nature 386, 569-577.
37. Reis, L.F.L., Ruffner, H., Stark, G., Aguet, M., and Weissmann, C. (1994). Mice devoid of interferon regulatory factor I (IRF-1) show normal expression of type I interferon genes. EMBO J. 13, 4798-4806.
38. Roeder, R.G. (1996). The role of general initiation factors in transcription by RNA polymerase II. Trends Biochem. Sci. 21, 327-335.
39. Sauer, F., Hansen, S.K., and Tjian, R. (1995). Multiple TAFIIs directing synergistic activation of transcription. Science 270, 1783-1788.
40. Thanos, D., and Maniatis, T. (1992). The high mobility group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFNβ gene. Cell 71, 777-789.
41. Thanos, D., and Maniatis, T. (1995a). Identification of the rel family members required for virus induction of the human β-interferon gene. Mol. Cell. Biol. 15, 152-164.
42. Thanos, D., and Maniatis, T. (1995b). Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome. Cell 83, 1091-1100.
43. Tjian, R., and Maniatis, T. (1994). Transcriptional activation: a complex puzzle with few easy pieces. Cell 77, 5-8.
44. Yie, J., Liang, S., Merika, M., and Thanos, D. (1997). Intra- and intermolecular cooperative binding of HMG I(Y) to the IFNβ promoter. Mol. Cell. Biol. 17, 3649-3662.