-
1
-
-
0034669991
-
Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins
-
Andre P, Denis CV, Ware J, Saffaripour S, Hynes RO, Ruggeri ZM, Wagner DD. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood 2000; 96: 3322-8.
-
(2000)
Blood
, vol.96
, pp. 3322-3328
-
-
Andre, P.1
Denis, C.V.2
Ware, J.3
Saffaripour, S.4
Hynes, R.O.5
Ruggeri, Z.M.6
Wagner, D.D.7
-
2
-
-
0036893186
-
ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions
-
Dong JF, Moake JL, Nolasco L, Bernardo A, Arceneaux W, Shrimpton CN, Schade AJ, McIntire LV, Fujikawa K, Lopez JA. ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions. Blood 2002; 100: 4033-9.
-
(2002)
Blood
, vol.100
, pp. 4033-4039
-
-
Dong, J.F.1
Moake, J.L.2
Nolasco, L.3
Bernardo, A.4
Arceneaux, W.5
Shrimpton, C.N.6
Schade, A.J.7
McIntire, L.V.8
Fujikawa, K.9
Lopez, J.A.10
-
3
-
-
41749101957
-
Pathogenesis of thrombotic microangiopathies
-
Zheng XL, Sadler JE. Pathogenesis of thrombotic microangiopathies. Annu Rev Pathol 2008; 3: 249-77.
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 249-277
-
-
Zheng, X.L.1
Sadler, J.E.2
-
4
-
-
75649138819
-
Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13
-
Wu T, Lin J, Cruz MA, Dong JF, Zhu C. Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13. Blood 2010; 115: 370-8.
-
(2010)
Blood
, vol.115
, pp. 370-378
-
-
Wu, T.1
Lin, J.2
Cruz, M.A.3
Dong, J.F.4
Zhu, C.5
-
5
-
-
66749099068
-
Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor
-
Zhang X, Halvorsen K, Zhang CZ, Wong WP, Springer TA. Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor. Science 2009; 324: 1330-4.
-
(2009)
Science
, vol.324
, pp. 1330-1334
-
-
Zhang, X.1
Halvorsen, K.2
Zhang, C.Z.3
Wong, W.P.4
Springer, T.A.5
-
6
-
-
17144408687
-
FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay
-
Kokame K, Nobe Y, Kokubo Y, Okayama A, Miyata T. FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay. Br J Haematol 2005; 129: 93-100.
-
(2005)
Br J Haematol
, vol.129
, pp. 93-100
-
-
Kokame, K.1
Nobe, Y.2
Kokubo, Y.3
Okayama, A.4
Miyata, T.5
-
7
-
-
0035807348
-
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
-
Levy GG, Nichols WC, Lian EC, Foroud T, McClintick JN, McGee BM, Yang AY, Siemieniak DR, Stark KR, Gruppo R, Sarode R, Shurin SB, Chandrasekaran V, Stabler SP, Sabio H, Bouhassira EE, Upshaw JD Jr, Ginsburg D, Tsai HM. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature 2001; 413: 488-94.
-
(2001)
Nature
, vol.413
, pp. 488-494
-
-
Levy, G.G.1
Nichols, W.C.2
Lian, E.C.3
Foroud, T.4
McClintick, J.N.5
McGee, B.M.6
Yang, A.Y.7
Siemieniak, D.R.8
Stark, K.R.9
Gruppo, R.10
Sarode, R.11
Shurin, S.B.12
Chandrasekaran, V.13
Stabler, S.P.14
Sabio, H.15
Bouhassira, E.E.16
Upshaw Jr., J.D.17
Ginsburg, D.18
Tsai, H.M.19
-
8
-
-
67049114094
-
Essential role of the disintegrin-like domain in ADAMTS13 function
-
de Groot R, Bardhan A, Ramroop N, Lane DA, Crawley JT. Essential role of the disintegrin-like domain in ADAMTS13 function. Blood 2009; 113: 5609-16.
-
(2009)
Blood
, vol.113
, pp. 5609-5616
-
-
de Groot, R.1
Bardhan, A.2
Ramroop, N.3
Lane, D.A.4
Crawley, J.T.5
-
9
-
-
77949882442
-
An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF
-
Pos W, Crawley JT, Fijnheer R, Voorberg J, Lane DA, Luken BM. An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF. Blood 2010; 115: 1640-9.
-
(2010)
Blood
, vol.115
, pp. 1640-1649
-
-
Pos, W.1
Crawley, J.T.2
Fijnheer, R.3
Voorberg, J.4
Lane, D.A.5
Luken, B.M.6
-
10
-
-
77950414918
-
Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor
-
Jin SY, Skipwith CG, Zheng XL. Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor. Blood 2010; 115: 2300-10.
-
(2010)
Blood
, vol.115
, pp. 2300-2310
-
-
Jin, S.Y.1
Skipwith, C.G.2
Zheng, X.L.3
-
11
-
-
72949104661
-
Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
-
Akiyama M, Takeda S, Kokame K, Takagi J, Miyata T. Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor. Proc Natl Acad Sci U S A 2009; 106: 19274-9.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19274-19279
-
-
Akiyama, M.1
Takeda, S.2
Kokame, K.3
Takagi, J.4
Miyata, T.5
-
12
-
-
77958172969
-
The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity
-
de Groot R, Lane DA, Crawley JT. The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity. Blood 2010; 116: 3064-72.
-
(2010)
Blood
, vol.116
, pp. 3064-3072
-
-
de Groot, R.1
Lane, D.A.2
Crawley, J.T.3
-
13
-
-
0042530524
-
Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13
-
Zheng X, Nishio K, Majerus EM, Sadler JE. Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13. J Biol Chem 2003; 278: 30136-41.
-
(2003)
J Biol Chem
, vol.278
, pp. 30136-30141
-
-
Zheng, X.1
Nishio, K.2
Majerus, E.M.3
Sadler, J.E.4
-
14
-
-
0142152440
-
ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage
-
Soejima K, Matsumoto M, Kokame K, Yagi H, Ishizashi H, Maeda H, Nozaki C, Miyata T, Fujimura Y, Nakagaki T. ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage. Blood 2003; 102: 3232-7.
-
(2003)
Blood
, vol.102
, pp. 3232-3237
-
-
Soejima, K.1
Matsumoto, M.2
Kokame, K.3
Yagi, H.4
Ishizashi, H.5
Maeda, H.6
Nozaki, C.7
Miyata, T.8
Fujimura, Y.9
Nakagaki, T.10
-
15
-
-
74049137935
-
ADAMTS13 mutations and polymorphisms in congenital thrombotic thrombocytopenic purpura
-
Lotta LA, Garagiola I, Palla R, Cairo A, Peyvandi F. ADAMTS13 mutations and polymorphisms in congenital thrombotic thrombocytopenic purpura. Hum Mutat 2010; 31: 11-9.
-
(2010)
Hum Mutat
, vol.31
, pp. 11-19
-
-
Lotta, L.A.1
Garagiola, I.2
Palla, R.3
Cairo, A.4
Peyvandi, F.5
-
16
-
-
77949903692
-
Survival and relapse in patients with thrombotic thrombocytopenic purpura
-
Hovinga JA, Vesely SK, Terrell DR, Lammle B, George JN. Survival and relapse in patients with thrombotic thrombocytopenic purpura. Blood 2010; 115: 1500-11.
-
(2010)
Blood
, vol.115
, pp. 1500-1511
-
-
Hovinga, J.A.1
Vesely, S.K.2
Terrell, D.R.3
Lammle, B.4
George, J.N.5
-
17
-
-
0142183462
-
Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura
-
Scheiflinger F, Knobl P, Trattner B, Plaimauer B, Mohr G, Dockal M, Dorner F, Rieger M. Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura. Blood 2003; 102: 3241-3.
-
(2003)
Blood
, vol.102
, pp. 3241-3243
-
-
Scheiflinger, F.1
Knobl, P.2
Trattner, B.3
Plaimauer, B.4
Mohr, G.5
Dockal, M.6
Dorner, F.7
Rieger, M.8
-
18
-
-
33746650438
-
Inhibitory autoantibodies against ADAMTS-13 in patients with thrombotic thrombocytopenic purpura bind ADAMTS-13 protease and may accelerate its clearance in vivo
-
Shelat SG, Smith P, Ai J, Zheng XL. Inhibitory autoantibodies against ADAMTS-13 in patients with thrombotic thrombocytopenic purpura bind ADAMTS-13 protease and may accelerate its clearance in vivo. J Thromb Haemost 2006; 4: 1707-17.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 1707-1717
-
-
Shelat, S.G.1
Smith, P.2
Ai, J.3
Zheng, X.L.4
-
19
-
-
33947594746
-
Prognostic value of anti-ADAMTS 13 antibody features (Ig isotype, titer, and inhibitory effect) in a cohort of 35 adult French patients undergoing a first episode of thrombotic microangiopathy with undetectable ADAMTS 13 activity
-
Ferrari S, Scheiflinger F, Rieger M, Mudde G, Wolf M, Coppo P, Girma JP, Azoulay E, Brun-Buisson C, Fakhouri F, Mira JP, Oksenhendler E, Poullin P, Rondeau E, Schleinitz N, Schlemmer B, Teboul JL, Vanhille P, Vernant JP, Meyer D, et al. Prognostic value of anti-ADAMTS 13 antibody features (Ig isotype, titer, and inhibitory effect) in a cohort of 35 adult French patients undergoing a first episode of thrombotic microangiopathy with undetectable ADAMTS 13 activity. Blood 2007; 109: 2815-22.
-
(2007)
Blood
, vol.109
, pp. 2815-2822
-
-
Ferrari, S.1
Scheiflinger, F.2
Rieger, M.3
Mudde, G.4
Wolf, M.5
Coppo, P.6
Girma, J.P.7
Azoulay, E.8
Brun-Buisson, C.9
Fakhouri, F.10
Mira, J.P.11
Oksenhendler, E.12
Poullin, P.13
Rondeau, E.14
Schleinitz, N.15
Schlemmer, B.16
Teboul, J.L.17
Vanhille, P.18
Vernant, J.P.19
Meyer, D.20
more..
-
20
-
-
40849114959
-
ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission
-
Peyvandi F, Lavoretano S, Palla R, Feys HB, Vanhoorelbeke K, Battaglioli T, Valsecchi C, Canciani MT, Fabris F, Zver S, Reti M, Mikovic D, Karimi M, Giuffrida G, Laurenti L, Mannucci PM. ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission. Haematologica 2008; 93: 232-9.
-
(2008)
Haematologica
, vol.93
, pp. 232-239
-
-
Peyvandi, F.1
Lavoretano, S.2
Palla, R.3
Feys, H.B.4
Vanhoorelbeke, K.5
Battaglioli, T.6
Valsecchi, C.7
Canciani, M.T.8
Fabris, F.9
Zver, S.10
Reti, M.11
Mikovic, D.12
Karimi, M.13
Giuffrida, G.14
Laurenti, L.15
Mannucci, P.M.16
-
21
-
-
43449135029
-
Relationship between ADAMTS13 activity in clinical remission and the risk of TTP relapse
-
Jin M, Casper TC, Cataland SR, Kennedy MS, Lin S, Li YJ, Wu HM. Relationship between ADAMTS13 activity in clinical remission and the risk of TTP relapse. Br J Haematol 2008; 141: 651-8.
-
(2008)
Br J Haematol
, vol.141
, pp. 651-658
-
-
Jin, M.1
Casper, T.C.2
Cataland, S.R.3
Kennedy, M.S.4
Lin, S.5
Li, Y.J.6
Wu, H.M.7
-
22
-
-
23744486523
-
ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases
-
Rieger M, Mannucci PM, Kremer Hovinga JA, Herzog A, Gerstenbauer G, Konetschny C, Zimmermann K, Scharrer I, Peyvandi F, Galbusera M, Remuzzi G, Bohm M, Plaimauer B, Lammle B, Scheiflinger F. ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases. Blood 2005; 106: 1262-7.
-
(2005)
Blood
, vol.106
, pp. 1262-1267
-
-
Rieger, M.1
Mannucci, P.M.2
Kremer Hovinga, J.A.3
Herzog, A.4
Gerstenbauer, G.5
Konetschny, C.6
Zimmermann, K.7
Scharrer, I.8
Peyvandi, F.9
Galbusera, M.10
Remuzzi, G.11
Bohm, M.12
Plaimauer, B.13
Lammle, B.14
Scheiflinger, F.15
-
23
-
-
70350006842
-
IgG subclass distribution of anti-ADAMTS13 antibodies in patients with acquired thrombotic thrombocytopenic purpura
-
Ferrari S, Mudde GC, Rieger M, Veyradier A, Kremer Hovinga JA, Scheiflinger F. IgG subclass distribution of anti-ADAMTS13 antibodies in patients with acquired thrombotic thrombocytopenic purpura. J Thromb Haemost 2009; 7: 1703-10.
-
(2009)
J Thromb Haemost
, vol.7
, pp. 1703-1710
-
-
Ferrari, S.1
Mudde, G.C.2
Rieger, M.3
Veyradier, A.4
Kremer Hovinga, J.A.5
Scheiflinger, F.6
-
24
-
-
2942588403
-
Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura
-
Klaus C, Plaimauer B, Studt JD, Dorner F, Lammle B, Mannucci PM, Scheiflinger F. Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura. Blood 2004; 103: 4514-9.
-
(2004)
Blood
, vol.103
, pp. 4514-4519
-
-
Klaus, C.1
Plaimauer, B.2
Studt, J.D.3
Dorner, F.4
Lammle, B.5
Mannucci, P.M.6
Scheiflinger, F.7
-
25
-
-
13844256432
-
The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura
-
Luken BM, Turenhout EA, Hulstein JJ, van Mourik JA, Fijnheer R, Voorberg J. The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura. Thromb Haemost 2005; 93: 267-74.
-
(2005)
Thromb Haemost
, vol.93
, pp. 267-274
-
-
Luken, B.M.1
Turenhout, E.A.2
Hulstein, J.J.3
van Mourik, J.A.4
Fijnheer, R.5
Voorberg, J.6
-
26
-
-
77956824177
-
Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura
-
Zheng XL, Wu HM, Shang D, Falls E, Skipwith CG, Cataland SR, Bennett CL, Kwaan HC. Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura. Haematologica 2010; 95: 1555-62.
-
(2010)
Haematologica
, vol.95
, pp. 1555-1562
-
-
Zheng, X.L.1
Wu, H.M.2
Shang, D.3
Falls, E.4
Skipwith, C.G.5
Cataland, S.R.6
Bennett, C.L.7
Kwaan, H.C.8
-
28
-
-
0033604610
-
Crystal structures of the membrane-binding C2 domain of human coagulation factor V
-
Macedo-Ribeiro S, Bode W, Huber R, Quinn-Allen MA, Kim SW, Ortel TL, Bourenkov GP, Bartunik HD, Stubbs MT, Kane WH, Fuentes-Prior P. Crystal structures of the membrane-binding C2 domain of human coagulation factor V. Nature 1999; 402: 434-9.
-
(1999)
Nature
, vol.402
, pp. 434-439
-
-
Macedo-Ribeiro, S.1
Bode, W.2
Huber, R.3
Quinn-Allen, M.A.4
Kim, S.W.5
Ortel, T.L.6
Bourenkov, G.P.7
Bartunik, H.D.8
Stubbs, M.T.9
Kane, W.H.10
Fuentes-Prior, P.11
-
29
-
-
33750069427
-
Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura
-
Luken BM, Kaijen PH, Turenhout EA, Hovinga JA, van Mourik JA, Fijnheer R, Voorberg J. Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura. J Thromb Haemost 2006; 4: 2355-64.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 2355-2364
-
-
Luken, B.M.1
Kaijen, P.H.2
Turenhout, E.A.3
Hovinga, J.A.4
van Mourik, J.A.5
Fijnheer, R.6
Voorberg, J.7
-
30
-
-
33748597666
-
Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP
-
Luken BM, Turenhout EA, Kaijen PH, Greuter MJ, Pos W, van Mourik JA, Fijnheer R, Voorberg J. Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP. Thromb Haemost 2006; 96: 295-301.
-
(2006)
Thromb Haemost
, vol.96
, pp. 295-301
-
-
Luken, B.M.1
Turenhout, E.A.2
Kaijen, P.H.3
Greuter, M.J.4
Pos, W.5
van Mourik, J.A.6
Fijnheer, R.7
Voorberg, J.8
-
31
-
-
28844490990
-
Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions
-
Tao Z, Peng Y, Nolasco L, Cal S, Lopez-Otin C, Li R, Moake JL, Lopez JA, Dong JF. Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions. Blood 2005; 106: 4139-45.
-
(2005)
Blood
, vol.106
, pp. 4139-4145
-
-
Tao, Z.1
Peng, Y.2
Nolasco, L.3
Cal, S.4
Lopez-Otin, C.5
Li, R.6
Moake, J.L.7
Lopez, J.A.8
Dong, J.F.9
-
32
-
-
22044446207
-
Cleavage of ultralarge multimers of von Willebrand factor by C-terminal-truncated mutants of ADAMTS-13 under flow
-
Tao Z, Wang Y, Choi H, Bernardo A, Nishio K, Sadler JE, Lopez JA, Dong JF. Cleavage of ultralarge multimers of von Willebrand factor by C-terminal-truncated mutants of ADAMTS-13 under flow. Blood 2005; 106: 141-3.
-
(2005)
Blood
, vol.106
, pp. 141-143
-
-
Tao, Z.1
Wang, Y.2
Choi, H.3
Bernardo, A.4
Nishio, K.5
Sadler, J.E.6
Lopez, J.A.7
Dong, J.F.8
-
33
-
-
34548834974
-
The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow
-
Zhang P, Pan W, Rux AH, Sachais BS, Zheng XL. The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow. Blood 2007; 110: 1887-94.
-
(2007)
Blood
, vol.110
, pp. 1887-1894
-
-
Zhang, P.1
Pan, W.2
Rux, A.H.3
Sachais, B.S.4
Zheng, X.L.5
-
34
-
-
67149121187
-
The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation
-
Banno F, Chauhan AK, Kokame K, Yang J, Miyata S, Wagner DD, Miyata T. The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation. Blood 2009; 113: 5323-9.
-
(2009)
Blood
, vol.113
, pp. 5323-5329
-
-
Banno, F.1
Chauhan, A.K.2
Kokame, K.3
Yang, J.4
Miyata, S.5
Wagner, D.D.6
Miyata, T.7
-
35
-
-
71449101329
-
ADAMTS13 bound to endothelial cells exhibits enhanced cleavage of von Willebrand factor
-
Vomund AN, Majerus EM. ADAMTS13 bound to endothelial cells exhibits enhanced cleavage of von Willebrand factor. J Biol Chem 2009; 284: 30925-32.
-
(2009)
J Biol Chem
, vol.284
, pp. 30925-30932
-
-
Vomund, A.N.1
Majerus, E.M.2
-
36
-
-
77957195023
-
Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus)
-
Feys HB, Roodt J, Vandeputte N, Pareyn I, Lamprecht S, van Rensburg WJ, Anderson PJ, Budde U, Louw VJ, Badenhorst PN, Deckmyn H, Vanhoorelbeke K. Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus). Blood 2010; 116: 2005-10.
-
(2010)
Blood
, vol.116
, pp. 2005-2010
-
-
Feys, H.B.1
Roodt, J.2
Vandeputte, N.3
Pareyn, I.4
Lamprecht, S.5
van Rensburg, W.J.6
Anderson, P.J.7
Budde, U.8
Louw, V.J.9
Badenhorst, P.N.10
Deckmyn, H.11
Vanhoorelbeke, K.12
-
37
-
-
26444551183
-
Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice
-
Motto DG, Chauhan AK, Zhu G, Homeister J, Lamb CB, Desch KC, Zhang W, Tsai HM, Wagner DD, Ginsburg D. Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice. J Clin Invest 2005; 115: 2752-61.
-
(2005)
J Clin Invest
, vol.115
, pp. 2752-2761
-
-
Motto, D.G.1
Chauhan, A.K.2
Zhu, G.3
Homeister, J.4
Lamb, C.B.5
Desch, K.C.6
Zhang, W.7
Tsai, H.M.8
Wagner, D.D.9
Ginsburg, D.10
-
38
-
-
59849089873
-
VH1-69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura
-
Pos W, Luken BM, Hovinga JA, Turenhout EA, Scheiflinger F, Dong JF, Fijnheer R, Voorberg J. VH1-69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura. J Thromb Haemost 2009; 7: 421-8.
-
(2009)
J Thromb Haemost
, vol.7
, pp. 421-428
-
-
Pos, W.1
Luken, B.M.2
Hovinga, J.A.3
Turenhout, E.A.4
Scheiflinger, F.5
Dong, J.F.6
Fijnheer, R.7
Voorberg, J.8
-
39
-
-
0020534965
-
Somatic generation of antibody diversity
-
Tonegawa S. Somatic generation of antibody diversity. Nature 1983; 302: 575-81.
-
(1983)
Nature
, vol.302
, pp. 575-581
-
-
Tonegawa, S.1
-
40
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky K. Clonal selection and learning in the antibody system. Nature 1996; 381: 751-8.
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
41
-
-
41749097734
-
Inhibitory monoclonal autoantibodies cloned from TTP patients show restricted gene usage, inhibit murine ADAMTS13, and are blocked by rabbit anti-idiotypic antibodies
-
ASH annual meeting abstract). Abstract 92.
-
Siegel D, Ostertag E. Inhibitory monoclonal autoantibodies cloned from TTP patients show restricted gene usage, inhibit murine ADAMTS13, and are blocked by rabbit anti-idiotypic antibodies. Blood (ASH annual meeting abstract). 2006; 108; Abstract 92.
-
(2006)
Blood
, vol.108
-
-
Siegel, D.1
Ostertag, E.2
-
42
-
-
0030040277
-
Interactions of protein antigens with antibodies
-
Davies DR, Cohen GH. Interactions of protein antigens with antibodies. Proc Natl Acad Sci U S A 1996; 93: 7-12.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 7-12
-
-
Davies, D.R.1
Cohen, G.H.2
-
43
-
-
62049083943
-
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
-
Sui J, Hwang WC, Perez S, Wei G, Aird D, Chen LM, Santelli E, Stec B, Cadwell G, Ali M, Wan H, Murakami A, Yammanuru A, Han T, Cox NJ, Bankston LA, Donis RO, Liddington RC, Marasco WA. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol 2009; 16: 265-73.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 265-273
-
-
Sui, J.1
Hwang, W.C.2
Perez, S.3
Wei, G.4
Aird, D.5
Chen, L.M.6
Santelli, E.7
Stec, B.8
Cadwell, G.9
Ali, M.10
Wan, H.11
Murakami, A.12
Yammanuru, A.13
Han, T.14
Cox, N.J.15
Bankston, L.A.16
Donis, R.O.17
Liddington, R.C.18
Marasco, W.A.19
-
44
-
-
0029982537
-
Genetic analysis of autoimmune disease
-
Vyse TJ, Todd JA. Genetic analysis of autoimmune disease. Cell 1996; 85: 311-8.
-
(1996)
Cell
, vol.85
, pp. 311-318
-
-
Vyse, T.J.1
Todd, J.A.2
-
45
-
-
25144446865
-
The incidence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: all patients, idiopathic patients, and patients with severe ADAMTS-13 deficiency
-
Terrell DR, Williams LA, Vesely SK, Lammle B, Hovinga JA, George JN. The incidence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: all patients, idiopathic patients, and patients with severe ADAMTS-13 deficiency. J Thromb Haemost 2005; 3: 1432-6.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1432-1436
-
-
Terrell, D.R.1
Williams, L.A.2
Vesely, S.K.3
Lammle, B.4
Hovinga, J.A.5
George, J.N.6
-
46
-
-
70350433584
-
Heterogeneous pathogenic processes of thrombotic microangiopathies in patients with connective tissue diseases
-
Matsuyama T, Kuwana M, Matsumoto M, Isonishi A, Inokuma S, Fujimura Y. Heterogeneous pathogenic processes of thrombotic microangiopathies in patients with connective tissue diseases. Thromb Haemost 2009; 102: 371-8.
-
(2009)
Thromb Haemost
, vol.102
, pp. 371-378
-
-
Matsuyama, T.1
Kuwana, M.2
Matsumoto, M.3
Isonishi, A.4
Inokuma, S.5
Fujimura, Y.6
-
47
-
-
3242705780
-
Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count, and mild renal involvement
-
Coppo P, Bengoufa D, Veyradier A, Wolf M, Bussel A, Millot GA, Malot S, Heshmati F, Mira JP, Boulanger E, Galicier L, Durey-Dragon MA, Fremeaux-Bacchi V, Ramakers M, Pruna A, Bordessoule D, Gouilleux V, Scrobohaci ML, Vernant JP, Moreau D, et al. Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count, and mild renal involvement. Medicine (Baltimore) 2004; 83: 233-44.
-
(2004)
Medicine (Baltimore)
, vol.83
, pp. 233-244
-
-
Coppo, P.1
Bengoufa, D.2
Veyradier, A.3
Wolf, M.4
Bussel, A.5
Millot, G.A.6
Malot, S.7
Heshmati, F.8
Mira, J.P.9
Boulanger, E.10
Galicier, L.11
Durey-Dragon, M.A.12
Fremeaux-Bacchi, V.13
Ramakers, M.14
Pruna, A.15
Bordessoule, D.16
Gouilleux, V.17
Scrobohaci, M.L.18
Vernant, J.P.19
Moreau, D.20
more..
-
48
-
-
70449503002
-
Innate receptors and microbes in induction of autoimmunity
-
Chervonsky A. Innate receptors and microbes in induction of autoimmunity. Curr Opin Immunol 2009; 21: 641-7.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 641-647
-
-
Chervonsky, A.1
-
49
-
-
20444438369
-
Paths to understanding the genetic basis of autoimmune disease
-
Rioux JD, Abbas AK. Paths to understanding the genetic basis of autoimmune disease. Nature 2005; 435: 584-9.
-
(2005)
Nature
, vol.435
, pp. 584-589
-
-
Rioux, J.D.1
Abbas, A.K.2
-
50
-
-
74649087411
-
Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link
-
Scully M, Brown J, Patel R, McDonald V, Brown CJ, Machin S. Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link. J Thromb Haemost 2010; 8: 257-62.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 257-262
-
-
Scully, M.1
Brown, J.2
Patel, R.3
McDonald, V.4
Brown, C.J.5
Machin, S.6
-
51
-
-
77952689917
-
HLA-DRB1*11: a strong risk factor for acquired severe ADAMTS13 deficiency-related idiopathic thrombotic thrombocytopenic purpura in Caucasians
-
Coppo P, Busson M, Veyradier A, Wynckel A, Poullin P, Azoulay E, Galicier L, Loiseau P. HLA-DRB1*11: a strong risk factor for acquired severe ADAMTS13 deficiency-related idiopathic thrombotic thrombocytopenic purpura in Caucasians. J Thromb Haemost 2010; 8: 856-9.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 856-859
-
-
Coppo, P.1
Busson, M.2
Veyradier, A.3
Wynckel, A.4
Poullin, P.5
Azoulay, E.6
Galicier, L.7
Loiseau, P.8
-
52
-
-
2542420893
-
Familial acquired thrombotic thrombocytopenic purpura: ADAMTS13 inhibitory autoantibodies in identical twins
-
Studt JD, Hovinga JA, Radonic R, Gasparovic V, Ivanovic D, Merkler M, Wirthmueller U, Dahinden C, Furlan M, Lammle B. Familial acquired thrombotic thrombocytopenic purpura: ADAMTS13 inhibitory autoantibodies in identical twins. Blood 2004; 103: 4195-7.
-
(2004)
Blood
, vol.103
, pp. 4195-4197
-
-
Studt, J.D.1
Hovinga, J.A.2
Radonic, R.3
Gasparovic, V.4
Ivanovic, D.5
Merkler, M.6
Wirthmueller, U.7
Dahinden, C.8
Furlan, M.9
Lammle, B.10
-
53
-
-
0032522952
-
Acquired deficiency of von Willebrand factor-cleaving protease in a patient with thrombotic thrombocytopenic purpura
-
Furlan M, Robles R, Solenthaler M, Lammle B. Acquired deficiency of von Willebrand factor-cleaving protease in a patient with thrombotic thrombocytopenic purpura. Blood 1998; 91: 2839-46.
-
(1998)
Blood
, vol.91
, pp. 2839-2846
-
-
Furlan, M.1
Robles, R.2
Solenthaler, M.3
Lammle, B.4
-
54
-
-
0347986724
-
Plasma therapy in thrombotic thrombocytopenic purpura: review of the literature and the Bern experience in a subgroup of patients with severe acquired ADAMTS-13 deficiency
-
Fontana S, Hovinga JA, Studt JD, Alberio L, Lammle B, Taleghani BM. Plasma therapy in thrombotic thrombocytopenic purpura: review of the literature and the Bern experience in a subgroup of patients with severe acquired ADAMTS-13 deficiency. Semin Hematol 2004; 41: 48-59.
-
(2004)
Semin Hematol
, vol.41
, pp. 48-59
-
-
Fontana, S.1
Hovinga, J.A.2
Studt, J.D.3
Alberio, L.4
Lammle, B.5
Taleghani, B.M.6
-
55
-
-
34848865000
-
Cyclosporin and plasma exchange in thrombotic thrombocytopenic purpura: long-term follow-up with serial analysis of ADAMTS13 activity
-
Cataland SR, Jin M, Lin S, Kennedy MS, Kraut EH, George JN, Wu HM. Cyclosporin and plasma exchange in thrombotic thrombocytopenic purpura: long-term follow-up with serial analysis of ADAMTS13 activity. Br J Haematol 2007; 139: 486-93.
-
(2007)
Br J Haematol
, vol.139
, pp. 486-493
-
-
Cataland, S.R.1
Jin, M.2
Lin, S.3
Kennedy, M.S.4
Kraut, E.H.5
George, J.N.6
Wu, H.M.7
-
56
-
-
77950347321
-
Infections and autoimmunity: the multifaceted relationship
-
Sfriso P, Ghirardello A, Botsios C, Tonon M, Zen M, Bassi N, Bassetto F, Doria A. Infections and autoimmunity: the multifaceted relationship. J Leukoc Biol 2010; 87: 385-95.
-
(2010)
J Leukoc Biol
, vol.87
, pp. 385-395
-
-
Sfriso, P.1
Ghirardello, A.2
Botsios, C.3
Tonon, M.4
Zen, M.5
Bassi, N.6
Bassetto, F.7
Doria, A.8
-
57
-
-
20044385554
-
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
-
Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat Med 2005; 11: 138-45.
-
(2005)
Nat Med
, vol.11
, pp. 138-145
-
-
Lang, K.S.1
Recher, M.2
Junt, T.3
Navarini, A.A.4
Harris, N.L.5
Freigang, S.6
Odermatt, B.7
Conrad, C.8
Ittner, L.M.9
Bauer, S.10
Luther, S.A.11
Uematsu, S.12
Akira, S.13
Hengartner, H.14
Zinkernagel, R.M.15
-
58
-
-
70449470318
-
Structural alterations in peptide-MHC recognition by self-reactive T cell receptors
-
Wucherpfennig KW, Call MJ, Deng L, Mariuzza R. Structural alterations in peptide-MHC recognition by self-reactive T cell receptors. Curr Opin Immunol 2009; 21: 590-5.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 590-595
-
-
Wucherpfennig, K.W.1
Call, M.J.2
Deng, L.3
Mariuzza, R.4
-
60
-
-
61949241207
-
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides
-
Harkiolaki M, Holmes SL, Svendsen P, Gregersen JW, Jensen LT, McMahon R, Friese MA, van Boxel G, Etzensperger R, Tzartos JS, Kranc K, Sainsbury S, Harlos K, Mellins ED, Palace J, Esiri MM, van der Merwe PA, Jones EY, Fugger L. T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Immunity 2009; 30: 348-57.
-
(2009)
Immunity
, vol.30
, pp. 348-357
-
-
Harkiolaki, M.1
Holmes, S.L.2
Svendsen, P.3
Gregersen, J.W.4
Jensen, L.T.5
McMahon, R.6
Friese, M.A.7
van Boxel, G.8
Etzensperger, R.9
Tzartos, J.S.10
Kranc, K.11
Sainsbury, S.12
Harlos, K.13
Mellins, E.D.14
Palace, J.15
Esiri, M.M.16
van der Merwe, P.A.17
Jones, E.Y.18
Fugger, L.19
-
61
-
-
77950563514
-
Influenza A infection triggers thrombotic thrombocytopenic purpura by producing the anti-ADAMTS13 IgG inhibitor
-
Kosugi N, Tsurutani Y, Isonishi A, Hori Y, Matsumoto M, Fujimura Y. Influenza A infection triggers thrombotic thrombocytopenic purpura by producing the anti-ADAMTS13 IgG inhibitor. Intern Med 2010; 49: 689-93.
-
(2010)
Intern Med
, vol.49
, pp. 689-693
-
-
Kosugi, N.1
Tsurutani, Y.2
Isonishi, A.3
Hori, Y.4
Matsumoto, M.5
Fujimura, Y.6
-
62
-
-
34548135253
-
ADAMTS13 activity and the presence of acquired inhibitors in human immunodeficiency virus-related thrombotic thrombocytopenic purpura
-
Gunther K, Garizio D, Nesara P. ADAMTS13 activity and the presence of acquired inhibitors in human immunodeficiency virus-related thrombotic thrombocytopenic purpura. Transfusion 2007; 47: 1710-6.
-
(2007)
Transfusion
, vol.47
, pp. 1710-1716
-
-
Gunther, K.1
Garizio, D.2
Nesara, P.3
-
63
-
-
0035245182
-
A syndrome resembling thrombotic thrombocytopenic purpura associated with human parvovirus B19 infection
-
Kok RH, Wolfhagen MJ, Klosters G. A syndrome resembling thrombotic thrombocytopenic purpura associated with human parvovirus B19 infection. Clin Infect Dis 2001; 32: 311-2.
-
(2001)
Clin Infect Dis
, vol.32
, pp. 311-312
-
-
Kok, R.H.1
Wolfhagen, M.J.2
Klosters, G.3
-
64
-
-
26444510751
-
Thrombotic thrombocytopenic purpura: proposal of a new pathogenic mechanism involving Helicobacter pylori infection
-
Franchini M. Thrombotic thrombocytopenic purpura: proposal of a new pathogenic mechanism involving Helicobacter pylori infection. Med Hypotheses 2005; 65: 1128-31.
-
(2005)
Med Hypotheses
, vol.65
, pp. 1128-1131
-
-
Franchini, M.1
-
65
-
-
13844292749
-
Development of ADAMTS13 inhibitor in a patient with hepatitis C virus-related liver cirrhosis causes thrombotic thrombocytopenic purpura
-
Yagita M, Uemura M, Nakamura T, Kunitomi A, Matsumoto M, Fujimura Y. Development of ADAMTS13 inhibitor in a patient with hepatitis C virus-related liver cirrhosis causes thrombotic thrombocytopenic purpura. J Hepatol 2005; 42: 420-1.
-
(2005)
J Hepatol
, vol.42
, pp. 420-421
-
-
Yagita, M.1
Uemura, M.2
Nakamura, T.3
Kunitomi, A.4
Matsumoto, M.5
Fujimura, Y.6
-
66
-
-
40949106512
-
Thrombotic thrombocytopenic purpura associated with Brucella infection
-
Kiki I, Gundogdu M, Albayrak B, Bilgic Y. Thrombotic thrombocytopenic purpura associated with Brucella infection. Am J Med Sci 2008; 335: 230-2.
-
(2008)
Am J Med Sci
, vol.335
, pp. 230-232
-
-
Kiki, I.1
Gundogdu, M.2
Albayrak, B.3
Bilgic, Y.4
-
67
-
-
80052764359
-
A case of severe thrombotic thrombocytopenic purpura with concomitant Legionella pneumonia: review of pathogenesis and treatment
-
DOI: 10.1097/MJT.0b013e3181d1b4a1.
-
Talebi T, Fernandez-Castro G, Montero AJ, Stefanovic A, Lian E. A case of severe thrombotic thrombocytopenic purpura with concomitant Legionella pneumonia: review of pathogenesis and treatment. Am J Ther 2010; DOI: 10.1097/MJT.0b013e3181d1b4a1.
-
(2010)
Am J Ther
-
-
Talebi, T.1
Fernandez-Castro, G.2
Montero, A.J.3
Stefanovic, A.4
Lian, E.5
-
68
-
-
18244373936
-
Understanding sex biases in immunity: effects of estrogen on the differentiation and function of antigen-presenting cells
-
Nalbandian G, Kovats S. Understanding sex biases in immunity: effects of estrogen on the differentiation and function of antigen-presenting cells. Immunol Res 2005; 31: 91-106.
-
(2005)
Immunol Res
, vol.31
, pp. 91-106
-
-
Nalbandian, G.1
Kovats, S.2
-
69
-
-
54249108556
-
The role of glucocorticoids and progestins in inflammatory, autoimmune, and infectious disease
-
Tait AS, Butts CL, Sternberg EM. The role of glucocorticoids and progestins in inflammatory, autoimmune, and infectious disease. J Leukoc Biol 2008; 84: 924-31.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 924-931
-
-
Tait, A.S.1
Butts, C.L.2
Sternberg, E.M.3
-
70
-
-
0034660472
-
Thrombotic thrombocytopenic purpura associated with clopidogrel
-
Bennett CL, Connors JM, Carwile JM, Moake JL, Bell WR, Tarantolo SR, McCarthy LJ, Sarode R, Hatfield AJ, Feldman MD, Davidson CJ, Tsai HM. Thrombotic thrombocytopenic purpura associated with clopidogrel. N Engl J Med 2000; 342: 1773-7.
-
(2000)
N Engl J Med
, vol.342
, pp. 1773-1777
-
-
Bennett, C.L.1
Connors, J.M.2
Carwile, J.M.3
Moake, J.L.4
Bell, W.R.5
Tarantolo, S.R.6
McCarthy, L.J.7
Sarode, R.8
Hatfield, A.J.9
Feldman, M.D.10
Davidson, C.J.11
Tsai, H.M.12
-
71
-
-
74549138555
-
Registry of 919 patients with thrombotic microangiopathies across Japan: database of Nara Medical University during 1998-2008
-
Fujimura Y, Matsumoto M. Registry of 919 patients with thrombotic microangiopathies across Japan: database of Nara Medical University during 1998-2008. Intern Med 2010; 49: 7-15.
-
(2010)
Intern Med
, vol.49
, pp. 7-15
-
-
Fujimura, Y.1
Matsumoto, M.2
-
72
-
-
63049106291
-
Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989-2008)
-
Zakarija A, Kwaan HC, Moake JL, Bandarenko N, Pandey DK, McKoy JM, Yarnold PR, Raisch DW, Winters JL, Raife TJ, Cursio JF, Luu TH, Richey EA, Fisher MJ, Ortel TL, Tallman MS, Zheng XL, Matsumoto M, Fujimura Y, Bennett CL. Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989-2008). Kidney Int Suppl 2009; 75: S20-4.
-
(2009)
Kidney Int Suppl
, vol.75
-
-
Zakarija, A.1
Kwaan, H.C.2
Moake, J.L.3
Bandarenko, N.4
Pandey, D.K.5
McKoy, J.M.6
Yarnold, P.R.7
Raisch, D.W.8
Winters, J.L.9
Raife, T.J.10
Cursio, J.F.11
Luu, T.H.12
Richey, E.A.13
Fisher, M.J.14
Ortel, T.L.15
Tallman, M.S.16
Zheng, X.L.17
Matsumoto, M.18
Fujimura, Y.19
Bennett, C.L.20
more..
-
73
-
-
78650675653
-
Role of the P2Y12 receptor in the modulation of murine dendritic cell function by ADP
-
Ben Addi A, Cammarata D, Conley PB, Boeynaems JM, Robaye B. Role of the P2Y12 receptor in the modulation of murine dendritic cell function by ADP. J Immunol 2010; 185: 5900-6.
-
(2010)
J Immunol
, vol.185
, pp. 5900-5906
-
-
Ben Addi, A.1
Cammarata, D.2
Conley, P.B.3
Boeynaems, J.M.4
Robaye, B.5
|