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Volumn 106, Issue 13, 2005, Pages 4139-4145

Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1; COMPLEMENT COMPONENT C1S; METALLOPROTEINASE; POLYPEPTIDE; PROCOLLAGEN C PROTEINASE; PROTEIN SUBUNIT; THROMBOSPONDIN; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

EID: 28844490990     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-05-2029     Document Type: Article
Times cited : (91)

References (39)
  • 1
    • 0031686041 scopus 로고    scopus 로고
    • Biochemistry and genetics of von Willebrand factor
    • Sadler JE. Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem. 1998;67:395-424.
    • (1998) Annu Rev Biochem , vol.67 , pp. 395-424
    • Sadler, J.E.1
  • 2
    • 0026001694 scopus 로고
    • The high molecular weight form of endothelial cell von Willebrand factor is released by the regulated pathway
    • Tsai HM, Nagel RL, Hatcher VB, Seaton AC, Sussman II. The high molecular weight form of endothelial cell von Willebrand factor is released by the regulated pathway. Br J Haematol. 1991;79:239-245.
    • (1991) Br J Haematol , vol.79 , pp. 239-245
    • Tsai, H.M.1    Nagel, R.L.2    Hatcher, V.B.3    Seaton, A.C.4    Sussman, I.I.5
  • 3
    • 0036624844 scopus 로고    scopus 로고
    • Ultralarge multimers of von Willebrand factor form spontaneous high-strength bonds with the platelet glycoprotein Ib-IX complex: Studies using optical tweezers
    • Arya M, Anvari B, Romo GM, et al. Ultralarge multimers of von Willebrand factor form spontaneous high-strength bonds with the platelet glycoprotein Ib-IX complex: studies using optical tweezers. Blood. 2002;99:3971-3977.
    • (2002) Blood , vol.99 , pp. 3971-3977
    • Arya, M.1    Anvari, B.2    Romo, G.M.3
  • 4
    • 0036893186 scopus 로고    scopus 로고
    • ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions
    • Dong JF, Moake JL, Nolasco L, et al. ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions. Blood. 2002;100:4033-4039.
    • (2002) Blood , vol.100 , pp. 4033-4039
    • Dong, J.F.1    Moake, J.L.2    Nolasco, L.3
  • 5
    • 0035798582 scopus 로고    scopus 로고
    • Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura
    • Zheng X, Chung D, Takayama TK, Majerus EM, Sadler JE, Fujikawa K. Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura. J Biol Chem. 2001;276:41059-41063.
    • (2001) J Biol Chem , vol.276 , pp. 41059-41063
    • Zheng, X.1    Chung, D.2    Takayama, T.K.3    Majerus, E.M.4    Sadler, J.E.5    Fujikawa, K.6
  • 6
    • 0035807348 scopus 로고    scopus 로고
    • Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
    • Levy GG, Nichols WC, Lian EC, et al. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature. 2001;413:488-494.
    • (2001) Nature , vol.413 , pp. 488-494
    • Levy, G.G.1    Nichols, W.C.2    Lian, E.C.3
  • 7
    • 0037160539 scopus 로고    scopus 로고
    • Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains
    • Cal S, Obaya AJ, Llamazares M, Garabaya C, Quesada V, Lopez-Otin C. Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains. Gene. 2002;283:49-62.
    • (2002) Gene , vol.283 , pp. 49-62
    • Cal, S.1    Obaya, A.J.2    Llamazares, M.3    Garabaya, C.4    Quesada, V.5    Lopez-Otin, C.6
  • 8
    • 0029925856 scopus 로고    scopus 로고
    • Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis
    • Furlan M, Robles R, Lammle B. Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis. Blood. 1996;87:4223-4234.
    • (1996) Blood , vol.87 , pp. 4223-4234
    • Furlan, M.1    Robles, R.2    Lammle, B.3
  • 9
    • 0026069774 scopus 로고
    • Heterogeneity of plasma von Willebrand factor multimers resulting from proteolysis of the constituent subunit
    • Dent JA, Galbusera M, Ruggeri ZM. Heterogeneity of plasma von Willebrand factor multimers resulting from proteolysis of the constituent subunit. J Clin Invest. 1991;88:774-782.
    • (1991) J Clin Invest , vol.88 , pp. 774-782
    • Dent, J.A.1    Galbusera, M.2    Ruggeri, Z.M.3
  • 10
    • 0029907370 scopus 로고    scopus 로고
    • Von Willebrand factor: Molecular size and functional activity
    • Furlan M. Von Willebrand factor: molecular size and functional activity. Ann Hematol. 1996;72:341-348.
    • (1996) Ann Hematol , vol.72 , pp. 341-348
    • Furlan, M.1
  • 11
    • 0037158606 scopus 로고    scopus 로고
    • Thrombotic microangiopathies
    • Moake JL. Thrombotic microangiopathies. N Engl J Med. 2002;347:589-600.
    • (2002) N Engl J Med , vol.347 , pp. 589-600
    • Moake, J.L.1
  • 12
    • 10744226155 scopus 로고    scopus 로고
    • Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome
    • Matsumoto M, Kokame K, Soejima K, et al. Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome. Blood. 2004;103:1305-1310.
    • (2004) Blood , vol.103 , pp. 1305-1310
    • Matsumoto, M.1    Kokame, K.2    Soejima, K.3
  • 13
    • 0942287728 scopus 로고    scopus 로고
    • Congenital thrombotic thrombocytopenic purpura in association with a mutation in the second CUB domain of ADAMTS13
    • Pimanda JE, Maekawa A, Wind T, Paxton J, Chesterman CN, Hogg PJ. Congenital thrombotic thrombocytopenic purpura in association with a mutation in the second CUB domain of ADAMTS13. Blood. 2004;103:627-629.
    • (2004) Blood , vol.103 , pp. 627-629
    • Pimanda, J.E.1    Maekawa, A.2    Wind, T.3    Paxton, J.4    Chesterman, C.N.5    Hogg, P.J.6
  • 14
    • 0037513434 scopus 로고    scopus 로고
    • Mutation analysis and clinical implications of von Willebrand factor-cleaving protease deficiency
    • Assink K, Schiphorst R, Allford S, et al. Mutation analysis and clinical implications of von Willebrand factor-cleaving protease deficiency. Kidney Int. 2003;63:1995-1999.
    • (2003) Kidney Int , vol.63 , pp. 1995-1999
    • Assink, K.1    Schiphorst, R.2    Allford, S.3
  • 15
    • 0012580388 scopus 로고    scopus 로고
    • ADAMTS13 gene mutation in congenital thrombotic thrombocytopenic purpura with previously reported normal VWF cleaving protease activity
    • Savasan S, Lee SK, Ginsburg D, Tsai HM. ADAMTS13 gene mutation in congenital thrombotic thrombocytopenic purpura with previously reported normal VWF cleaving protease activity. Blood. 2003;101:4449-4451.
    • (2003) Blood , vol.101 , pp. 4449-4451
    • Savasan, S.1    Lee, S.K.2    Ginsburg, D.3    Tsai, H.M.4
  • 16
    • 0036460780 scopus 로고    scopus 로고
    • Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura
    • Tsai HM. Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura. J Mol Med. 2002;80:639-647.
    • (2002) J Mol Med , vol.80 , pp. 639-647
    • Tsai, H.M.1
  • 17
    • 0036683408 scopus 로고    scopus 로고
    • Von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome
    • Remuzzi G, Galbusera M, Noris M, et al. von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. Blood. 2002;100:778-785.
    • (2002) Blood , vol.100 , pp. 778-785
    • Remuzzi, G.1    Galbusera, M.2    Noris, M.3
  • 18
    • 0038813798 scopus 로고    scopus 로고
    • Rituximab induces remission of cerebral ischemia caused by thrombotic thrombocytopenic purpura
    • Tsai HM, Shulman K. Rituximab induces remission of cerebral ischemia caused by thrombotic thrombocytopenic purpura. Eur J Haematol. 2003;70:183-185.
    • (2003) Eur J Haematol , vol.70 , pp. 183-185
    • Tsai, H.M.1    Shulman, K.2
  • 19
    • 0037458230 scopus 로고    scopus 로고
    • Remission of chronic thrombotic thrombocytopenic purpura after treatment with cyclophosphamide and rituximab
    • Zheng X, Pallera AM, Goodnough LT, Sadler JE, Blinder MA. Remission of chronic thrombotic thrombocytopenic purpura after treatment with cyclophosphamide and rituximab. Ann Intern Med. 2003;138:105-108.
    • (2003) Ann Intern Med , vol.138 , pp. 105-108
    • Zheng, X.1    Pallera, A.M.2    Goodnough, L.T.3    Sadler, J.E.4    Blinder, M.A.5
  • 20
    • 0027190974 scopus 로고
    • The CUB domain: A widespread module in developmentally regulated proteins
    • Bork P, Beckmann G. The CUB domain: a widespread module in developmentally regulated proteins. J Mol Biol. 1993;231:539-545.
    • (1993) J Mol Biol , vol.231 , pp. 539-545
    • Bork, P.1    Beckmann, G.2
  • 21
    • 0032923230 scopus 로고    scopus 로고
    • Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains
    • Kim MG, Chen C, Lyu MS, et al. Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains. Immunogenetics. 1999;49:420-428.
    • (1999) Immunogenetics , vol.49 , pp. 420-428
    • Kim, M.G.1    Chen, C.2    Lyu, M.S.3
  • 22
    • 0037195861 scopus 로고    scopus 로고
    • Identification of a novel family of cell-surface proteins expressed in human vascular endothelium
    • Yang RB, Ng CK, Wasserman SM, et al. Identification of a novel family of cell-surface proteins expressed in human vascular endothelium. J Biol Chem. 2002;277:46364-46373.
    • (2002) J Biol Chem , vol.277 , pp. 46364-46373
    • Yang, R.B.1    Ng, C.K.2    Wasserman, S.M.3
  • 23
    • 2942588403 scopus 로고    scopus 로고
    • Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura
    • Klaus C, Plaimauer B, Studt JD, et al. Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura. Blood. 2004;103:4514-4519.
    • (2004) Blood , vol.103 , pp. 4514-4519
    • Klaus, C.1    Plaimauer, B.2    Studt, J.D.3
  • 24
    • 12144287549 scopus 로고    scopus 로고
    • P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface
    • Padilla A, Moake JL, Bernardo A, et al. P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface. Blood. 2004;103:2150-2156.
    • (2004) Blood , vol.103 , pp. 2150-2156
    • Padilla, A.1    Moake, J.L.2    Bernardo, A.3
  • 25
    • 0043032701 scopus 로고    scopus 로고
    • ADAMTS-13 metalloprotease interacts with the endothelial cell-derived ultra-large von Willebrand factor
    • Dong JF, Moake JL, Bernardo A, et al.ADAMTS-13 metalloprotease interacts with the endothelial cell-derived ultra-large von Willebrand factor. J Biol Chem. 2003;278:29633-29639.
    • (2003) J Biol Chem , vol.278 , pp. 29633-29639
    • Dong, J.F.1    Moake, J.L.2    Bernardo, A.3
  • 26
    • 0042530524 scopus 로고    scopus 로고
    • Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13
    • Zheng X, Nishio K, Majerus EM, Sadler JE. Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13. J Biol Chem. 2003;278:30136-30141.
    • (2003) J Biol Chem , vol.278 , pp. 30136-30141
    • Zheng, X.1    Nishio, K.2    Majerus, E.M.3    Sadler, J.E.4
  • 27
    • 0344875565 scopus 로고    scopus 로고
    • Cleavage of the ADAMTS13 propeptide is not required for protease activity
    • Majerus EM, Zheng X, Tuley EA, Sadler JE. Cleavage of the ADAMTS13 propeptide is not required for protease activity. J Biol Chem. 2003;278:46643-46648.
    • (2003) J Biol Chem , vol.278 , pp. 46643-46648
    • Majerus, E.M.1    Zheng, X.2    Tuley, E.A.3    Sadler, J.E.4
  • 28
    • 0019442145 scopus 로고
    • The complex multimeric composition of factor VIII/von Willebrand factor
    • Ruggeri ZM, Zimmerman TS. The complex multimeric composition of factor VIII/von Willebrand factor. Blood. 1981;57:1140-1143.
    • (1981) Blood , vol.57 , pp. 1140-1143
    • Ruggeri, Z.M.1    Zimmerman, T.S.2
  • 29
    • 0020428664 scopus 로고
    • Unusually large plasma factor VIII: Von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura
    • Moake JL, Rudy CK, Troll JH, et al. Unusually large plasma factor VIII: von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura. N Engl J Med. 1982;307:1432-1435.
    • (1982) N Engl J Med , vol.307 , pp. 1432-1435
    • Moake, J.L.1    Rudy, C.K.2    Troll, J.H.3
  • 30
    • 0022852282 scopus 로고
    • Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation
    • Moake JL, Turner NA, Stathopoulos NA, Nolasco LH, Hellums JD. Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation. J Clin Invest. 1986;78:1456-1461.
    • (1986) J Clin Invest , vol.78 , pp. 1456-1461
    • Moake, J.L.1    Turner, N.A.2    Stathopoulos, N.A.3    Nolasco, L.H.4    Hellums, J.D.5
  • 31
    • 0024734977 scopus 로고
    • Abnormalities of von Willebrand factor multimers in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome
    • Moake JL, McPherson PD. Abnormalities of von Willebrand factor multimers in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. Am J Med. 1989;87:9N-15N.
    • (1989) Am J Med , vol.87
    • Moake, J.L.1    McPherson, P.D.2
  • 32
    • 22044446207 scopus 로고    scopus 로고
    • Cleavage of ultralarge multimers of Von Willebrand factor by C-terminal truncated mutants of ADAMTS-13 under flow
    • Tao Z, Wang Y, Choi H, et al. Cleavage of ultralarge multimers of Von Willebrand factor by C-terminal truncated mutants of ADAMTS-13 under flow. Blood. 2005;106:141-143.
    • (2005) Blood , vol.106 , pp. 141-143
    • Tao, Z.1    Wang, Y.2    Choi, H.3
  • 33
    • 0142152440 scopus 로고    scopus 로고
    • ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage
    • Soejima K, Matsumoto M, Kokame K, et al. ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage. Blood. 2003;102:3232-3237.
    • (2003) Blood , vol.102 , pp. 3232-3237
    • Soejima, K.1    Matsumoto, M.2    Kokame, K.3
  • 34
    • 0031255268 scopus 로고    scopus 로고
    • The crystal structures of two spermadhesins reveal the CUB domain fold
    • Romero A, Romao MJ, Varela PF, et al. The crystal structures of two spermadhesins reveal the CUB domain fold. Nat Struct Biol. 1997;4:783-788.
    • (1997) Nat Struct Biol , vol.4 , pp. 783-788
    • Romero, A.1    Romao, M.J.2    Varela, P.F.3
  • 35
    • 0346095396 scopus 로고    scopus 로고
    • Cleavage of von Willebrand factor by ADAMTS-13 on endothelial cells
    • López JA, Dong JF. Cleavage of von Willebrand factor by ADAMTS-13 on endothelial cells. Semin Hematol. 2004;41:15-23.
    • (2004) Semin Hematol , vol.41 , pp. 15-23
    • López, J.A.1    Dong, J.F.2
  • 36
    • 0028266474 scopus 로고
    • Shear stress enhances the proteolysis of von Willebrand factor in normal plasma
    • Tsai HM, Sussman II, Nagel RL. Shear stress enhances the proteolysis of von Willebrand factor in normal plasma. Blood. 1994;83:2171-2179.
    • (1994) Blood , vol.83 , pp. 2171-2179
    • Tsai, H.M.1    Sussman, I.I.2    Nagel, R.L.3
  • 37
    • 0034641659 scopus 로고    scopus 로고
    • Proteolysis of von Willebrand factor and shear stress-induced platelet aggregation in patients with aortic valve stenosis
    • Pareti FI, Lattuada A, Bressi C, et al. Proteolysis of von Willebrand factor and shear stress-induced platelet aggregation in patients with aortic valve stenosis. Circulation. 2000;102:1290-1295.
    • (2000) Circulation , vol.102 , pp. 1290-1295
    • Pareti, F.I.1    Lattuada, A.2    Bressi, C.3
  • 38
    • 22044436752 scopus 로고    scopus 로고
    • ADAMTS13 binds VWF via its C-terminal CUB2 domain
    • Zhang W, Motto D, Ginsburg D. ADAMTS13 binds VWF via its C-terminal CUB2 domain [abstract]. Blood. 2004;104:39a.
    • (2004) Blood , vol.104
    • Zhang, W.1    Motto, D.2    Ginsburg, D.3
  • 39
    • 20444454641 scopus 로고    scopus 로고
    • Binding of ADAMTS13 to von Willebrand factor
    • Majerus EM, Anderson PJ, Sadler JE. Binding of ADAMTS13 to von Willebrand factor. J Biol Chem. 2005;280:21773-21778.
    • (2005) J Biol Chem , vol.280 , pp. 21773-21778
    • Majerus, E.M.1    Anderson, P.J.2    Sadler, J.E.3


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