-
1
-
-
77954187741
-
DNA topoisomerases and their poisoning by anticancer and antibacterial drugs
-
Pommier Y, Leo E, Zhang H, Marchand C (2010) DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem Biol 17:421-433
-
(2010)
Chem Biol
, vol.17
, pp. 421-433
-
-
Pommier, Y.1
Leo, E.2
Zhang, H.3
Marchand, C.4
-
3
-
-
0027787743
-
Pharmacokinetics and metabolism of anthracyclines
-
Robert J, Gianni L (1993) Pharmacokinetics and metabolism of anthracyclines. Cancer Surv 17:219-252
-
(1993)
Cancer Surv
, vol.17
, pp. 219-252
-
-
Robert, J.1
Gianni, L.2
-
4
-
-
1242272119
-
Oxidative degradation of cardiotoxic anticancer anthracyclines to phthalic acids: Novel function for ferrylmyoglobin
-
DOI 10.1074/jbc.M306568200
-
Cartoni A, Menna P, Salvatorelli E et al (2004) Oxidative degradation of cardiotoxic anticancer anthracyclines to phthalic acids. Novel function or ferrylmyoglobin. J Biol Chem 279:5088-5099 (Pubitemid 38220525)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.7
, pp. 5088-5099
-
-
Cartoni, A.1
Menna, P.2
Salvatorelli, E.3
Braghiroli, D.4
Giampietro, R.5
Animati, F.6
Urbani, A.7
Del, B.P.8
Minotti, G.9
-
5
-
-
2642566088
-
Anthracyclines: Molecular advances and pharmacologie developments in antitumor activity and cardiotoxicity
-
DOI 10.1124/pr.56.2.6
-
Minotti G, Menna P, Salvatorelli E et al (2004) Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 56:185-229 (Pubitemid 38720829)
-
(2004)
Pharmacological Reviews
, vol.56
, Issue.2
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
Cairo, G.4
Gianni, L.5
-
6
-
-
77954533071
-
Differences in accumulation of anthracyclines daunorubicin, doxorubicin and epirubicin in rat tissues revealed by immunocytochemistry
-
Shin M, Matsunaga H, Fujiwara K (2010) Differences in accumulation of anthracyclines daunorubicin, doxorubicin and epirubicin in rat tissues revealed by immunocytochemistry. Histochem Cell Biol 133:677-682
-
(2010)
Histochem Cell Biol
, vol.133
, pp. 677-682
-
-
Shin, M.1
Matsunaga, H.2
Fujiwara, K.3
-
7
-
-
75149193249
-
Anthracycline degradation in cardiomyocytes: A journey to oxidative survival
-
Menna P, Salvatorelli E, Minotti G (2010) Anthracycline degradation in cardiomyocytes: a journey to oxidative survival. Chem Res Toxicol 23:6-10
-
(2010)
Chem Res Toxicol
, vol.23
, pp. 6-10
-
-
Menna, P.1
Salvatorelli, E.2
Minotti, G.3
-
10
-
-
0036524494
-
Molecular biology of doxorubicin-induced cardiomyopathy
-
Umlauf J, Horky M (2002) Molecular biology of doxorubicin-induced cardiomyopathy. Exp Clin Cardiol 7:35-39 (Pubitemid 36104228)
-
(2002)
Experimental and Clinical Cardiology
, vol.7
, Issue.1
, pp. 35-39
-
-
Umlauf, J.1
Horky, M.2
-
11
-
-
23044447053
-
Molecular pharmacology of the interaction of anthracyclines with iron
-
DOI 10.1124/mol.105.013383
-
Xu X, Persson HL, Richardson DR (2005) Molecular pharmacology of the interaction of anthracyclines with iron. Mol Pharmacol 68:261-271 (Pubitemid 41058288)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.2
, pp. 261-271
-
-
Xu, X.1
Persson, H.L.2
Richardson, D.R.3
-
12
-
-
0035576817
-
Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: Evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy
-
Minotti G, Ronchi R, Salvatorelli E et al (2001) Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy. Cancer Res 61:8422-8428 (Pubitemid 33131119)
-
(2001)
Cancer Research
, vol.61
, Issue.23
, pp. 8422-8428
-
-
Minotti, G.1
Ronchi, R.2
Salvatorelli, E.3
Menna, P.4
Cairo, G.5
-
13
-
-
74549137240
-
Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation: A key role for I(Ks)
-
Ducroq J, Moha ou Maati H, Guilbot S et al (2010) Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation: a key role for I(Ks). Br J Pharmacol 159:93-101
-
(2010)
Br J Pharmacol
, vol.159
, pp. 93-101
-
-
Ducroq, J.1
Mohaou Maati, H.2
Guilbot, S.3
-
14
-
-
57149134269
-
Dexrazoxane protects against doxorubicin-induced cardiomyopathy: Upregulation of Akt and Erk phosphorylation in a rat model
-
Xiang P, Deng HY, Li K et al (2009) Dexrazoxane protects against doxorubicin-induced cardiomyopathy: upregulation of Akt and Erk phosphorylation in a rat model. Cancer Chemother Pharmacol 63:343-349
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 343-349
-
-
Xiang, P.1
Deng, H.Y.2
Li, K.3
-
15
-
-
0141816698
-
Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin
-
DOI 10.1182/blood-2003-03-0869
-
Miranda CJ, Makui H, Soares RJ et al (2003) Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin. Blood 102:2574-2580 (Pubitemid 37193598)
-
(2003)
Blood
, vol.102
, Issue.7
, pp. 2574-2580
-
-
Miranda, C.J.1
Makui, H.2
Soares, R.J.3
Bilodeau, M.4
Mui, J.5
Vali, H.6
Bertrand, R.7
Andrews, N.C.8
Santos, M.M.9
-
17
-
-
66949171305
-
Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron
-
Simunek T, Sterba M, Popelova O et al (2009) Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacol Rep 61:154-171
-
(2009)
Pharmacol Rep
, vol.61
, pp. 154-171
-
-
Simunek, T.1
Sterba, M.2
Popelova, O.3
-
18
-
-
70450260555
-
Cardiomyocyte death in doxorubicin-induced cardiotoxicity
-
Warsz
-
Zhang YW, Shi J, Li YJ, Wei L (2009) Cardiomyocyte death in doxorubicin-induced cardiotoxicity. Arch Immunol Ther Exp (Warsz) 57:435-445
-
(2009)
Arch Immunol Ther Exp
, vol.57
, pp. 435-445
-
-
Zhang, Y.W.1
Shi, J.2
Li, Y.J.3
Wei, L.4
-
19
-
-
34548361626
-
Role of mtDNA lesions in anthracycline cardiotoxicity
-
DOI 10.1007/s12012-007-0009-1
-
Lebrecht D, Walker UA (2007) Role of mtDNA lesions in anthracycline cardiotoxicity. Cardiovasc Toxicol 7:108-113 (Pubitemid 47339856)
-
(2007)
Cardiovascular Toxicology
, vol.7
, Issue.2
, pp. 108-113
-
-
Lebrecht, D.1
Walker, U.A.2
-
20
-
-
33748420367
-
DNA damage is an early event in doxorubicin-induced cardiac myocyte death
-
DOI 10.1152/ajpheart.00738.2005
-
L'Ecuyer T, Sanjeev S, Thomas R et al (2006) DNA damage is an early event in doxorubicin-induced cardiac myocyte death. Am J Physiol Heart Circ Physiol 291:H1273-H1280 (Pubitemid 44343672)
-
(2006)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.291
, Issue.3
-
-
L'Ecuyer, T.1
Sanjeev, S.2
Thomas, R.3
Novak, R.4
Das, L.5
Campbell, W.6
Vander, H.R.7
-
21
-
-
0029941234
-
Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicin
-
DOI 10.1006/jmcc.1996.0095
-
Solem LE, Heller LJ, Wallace KB (1996) Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicin. J Mol Cell Cardiol 28:1023-1032 (Pubitemid 26169308)
-
(1996)
Journal of Molecular and Cellular Cardiology
, vol.28
, Issue.5
, pp. 1023-1032
-
-
Solem, L.E.1
Heller, L.J.2
Wallace, K.B.3
Wallace, K.B.4
-
22
-
-
0043237846
-
Doxorubicin-induced cardiac mitochondrionopathy
-
Wallace KB (2003) Doxorubicin-induced cardiac mitochondrionopathy. J Pharmacol Toxicol Methods 93:105-115
-
(2003)
J Pharmacol Toxicol Methods
, vol.93
, pp. 105-115
-
-
Wallace, K.B.1
-
23
-
-
34548299678
-
Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis
-
Wallace KB (2007) Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis. Cardiovasc Toxicol 7:101-107
-
(2007)
Cardiovasc Toxicol
, vol.7
, pp. 101-107
-
-
Wallace, K.B.1
-
24
-
-
0035863469
-
Cumulative and irreversible cardiac mitochondrial dysfunction induced by doxorubicin
-
Zhou S, Starkov A, Froberg MK et al (2001) Cumulative and irreversible cardiac mitochondrial dysfunction induced by doxorubicin. Cancer Res 61:771-777 (Pubitemid 32128645)
-
(2001)
Cancer Research
, vol.61
, Issue.2
, pp. 771-777
-
-
Zhou, S.1
Starkov, A.2
Froberg, M.K.3
Leino, R.L.4
Wallace, K.B.5
-
25
-
-
1342325523
-
Pifithrin-alpha protects against doxorubicin-induced apoptosis and acute cardiotoxicity in mice
-
Liu X, Chua CC, Gao J et al (2004) Pifithrin-alpha protects against doxorubicin-induced apoptosis and acute cardiotoxicity in mice. Am J Physiol Heart Circ Physiol 286:H933-H939 (Pubitemid 38248606)
-
(2004)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.286
, Issue.3
-
-
Liu, X.1
Chua, C.C.2
Gao, J.3
Chen, Z.4
Landy, C.L.C.5
Hamdy, R.6
Chua, B.H.L.7
-
26
-
-
57049095435
-
ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes
-
Liu J, Mao W, Ding B, Liang CS (2008) ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes. Am J Physiol Heart Circ Physiol 295:H1956-H1965
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Liu, J.1
Mao, W.2
Ding, B.3
Liang, C.S.4
-
27
-
-
2342619408
-
Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity
-
DOI 10.1073/pnas.0401833101
-
Aries A, Paradis P, Lefebvre C et al (2004) Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity. Proc Natl Acad Sci U S A 101:6975-6980 (Pubitemid 38596428)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.18
, pp. 6975-6980
-
-
Aries, A.1
Paradis, P.2
Lefebvre, C.3
Schwartz, R.J.4
Nemer, M.5
-
28
-
-
0037311110
-
Anthracycline-induced suppression of GATA-4 transcription factor: Implication in the regulation of cardiac myocyte apoptosis
-
DOI 10.1124/mol.63.2.368
-
Kim Y, Ma AG, Kitta K et al (2003) Anthracycline-induced suppression of GATA-4 transcription factor: implication in the regulation of cardiac myocyte apoptosis. Mol Pharmacol 63:368-377 (Pubitemid 36158372)
-
(2003)
Molecular Pharmacology
, vol.63
, Issue.2
, pp. 368-377
-
-
Kim, Y.1
Ma, A.-G.2
Kitta, K.3
Fitch, S.N.4
Ikeda, T.5
Ihara, Y.6
Simon, A.R.7
Evans, T.8
Suzuki, Y.J.9
-
29
-
-
79952833333
-
Mechanism of anthracycline-mediated down-regulation of GATA4 in the heart
-
Park AM, Nagase H, Liu L et al (2010) Mechanism of anthracycline-mediated down-regulation of GATA4 in the heart. Cardiovasc Res 90:97-104
-
(2010)
Cardiovasc Res
, vol.90
, pp. 97-104
-
-
Park, A.M.1
Nagase, H.2
Liu, L.3
-
30
-
-
10744230132
-
Expression of p300 protects cardiac myocytes from apoptosis in vivo
-
DOI 10.1016/j.bbrc.2004.01.105
-
Kawamura T, Hasegawa K, Morimoto T et al (2004) Expression of p300 protects cardiac myocytes from apoptosis in vivo. Biochem Biophys Res Commun 315:733-738 (Pubitemid 38232648)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.315
, Issue.3
, pp. 733-738
-
-
Kawamura, T.1
Hasegawa, K.2
Morimoto, T.3
Iwai-Kanai, E.4
Miyamoto, S.5
Kawase, Y.6
Ono, K.7
Wada, H.8
Akao, M.9
Kita, T.10
-
31
-
-
15044342095
-
Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells
-
DOI 10.1128/MCB.25.7.2673-2687.2005
-
Poizat C, Puri PL, Bai Y, Kedes L (2005) Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells. Mol Cell Biol 25:2673-2687 (Pubitemid 40381631)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.7
, pp. 2673-2687
-
-
Poizat, C.1
Puri, P.L.2
Bai, Y.3
Kedes, L.4
-
32
-
-
0035957953
-
CREB-binding protein and p300 in transcriptional regulation
-
Vo N, Goodman RH (2001) CREB-binding protein and p300 in transcriptional regulation. J Biol Chem 276:13505-13508
-
(2001)
J Biol Chem
, vol.276
, pp. 13505-13508
-
-
Vo, N.1
Goodman, R.H.2
-
33
-
-
0033533720
-
Function for p300 and not CBP in the apoptotic response to DNA damage
-
DOI 10.1038/sj.onc.1202930
-
Yuan ZM, Huang Y, Ishiko T et al (1999) Function for p300 and not CBP in the apoptotic response to DNA damage. Oncogene 18:5714-5717 (Pubitemid 29497606)
-
(1999)
Oncogene
, vol.18
, Issue.41
, pp. 5714-5717
-
-
Yuan, Z.-M.1
Huang, Y.2
Ishiko, T.3
Nakada, S.4
Utsugisawa, T.5
Shioya, H.6
Utsugisawa, Y.7
Shi, Y.8
Weichselbaum, R.9
Kufe, D.10
-
34
-
-
73649099845
-
Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death
-
Kobayashi S, Volden P, Timm D et al (2010) Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death. J Biol Chem 285:793-804
-
(2010)
J Biol Chem
, vol.285
, pp. 793-804
-
-
Kobayashi, S.1
Volden, P.2
Timm, D.3
-
35
-
-
27644467802
-
Autophagy in cardiac myocyte homeostasis, aging, and pathology
-
DOI 10.1016/j.cardiores.2005.08.014, PII S0008636305004177
-
Terman A, Brunk UT (2005) Autophagy in cardiac myocyte homeostasis, aging, and pathology. Cardiovasc Res 68:355-365 (Pubitemid 41566555)
-
(2005)
Cardiovascular Research
, vol.68
, Issue.3
, pp. 355-365
-
-
Terman, A.1
Brunk, U.T.2
-
37
-
-
33846189759
-
Control of Macroautophagy by Calcium, Calmodulin-Dependent Kinase Kinase-beta, and Bcl-2
-
DOI 10.1016/j.molcel.2006.12.009, PII S1097276506008458
-
Hoyer-Hansen M, Bastholm L, Szyniarowski P et al (2007) Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol Cell 25:193-205 (Pubitemid 46109606)
-
(2007)
Molecular Cell
, vol.25
, Issue.2
, pp. 193-205
-
-
Hoyer-Hansen, M.1
Bastholm, L.2
Szyniarowski, P.3
Campanella, M.4
Szabadkai, G.5
Farkas, T.6
Bianchi, K.7
Fehrenbacher, N.8
Elling, F.9
Rizzuto, R.10
Mathiasen, I.S.11
Jaattela, M.12
-
38
-
-
34548037901
-
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
-
DOI 10.1038/sj.cdd.4402200, PII 4402200
-
Hoyer-Hansen M, Jaattela M (2007) Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death Differ 14:1576-1582 (Pubitemid 47278843)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.9
, pp. 1576-1582
-
-
Hoyer-Hansen, M.1
Jaattela, M.2
-
39
-
-
0036858041
-
Oxidative stress and apoptosis in heart dysfunction
-
DOI 10.1007/s00059-002-2430-3
-
Kumar D, Lou H, Singal PK (2002) Oxidative stress and apoptosis in heart dysfunction. Herz 27:662-668 (Pubitemid 35415251)
-
(2002)
Herz
, vol.27
, Issue.7
, pp. 662-668
-
-
Kumar, D.1
Lou, H.2
Singal, P.K.3
-
41
-
-
0021187494
-
Cellular basis for adriamycin-induced augmentation of cell-mediated cytotoxicity in culture
-
Ehrke MJ, Ryoyama K, Cohen SA (1984) Cellular basis for adriamycin-induced augmentation of cell-mediated cytotoxicity in culture. Cancer Res 44:2497-2504 (Pubitemid 14108333)
-
(1984)
Cancer Research
, vol.44
, Issue.6
, pp. 2497-2504
-
-
Ehrke, M.J.1
Ryoyama, K.2
Cohen, S.A.3
-
42
-
-
0026631127
-
Adriamycin-induced modulation of host defenses in tumor-bearing mice
-
Maccubbin DL, Wing KR, Mace KF et al (1992) Adriamycin-induced modulation of host defenses in tumor-bearing mice. Cancer Res 52:3572-3576
-
(1992)
Cancer Res
, vol.52
, pp. 3572-3576
-
-
Maccubbin, D.L.1
Wing, K.R.2
Mace, K.F.3
-
43
-
-
0019499884
-
Adriamycin-activated macrophages as tumor growth inhibitors
-
Haskill JS (1981) Adriamycin-activated macrophages as tumor growth inhibitors. Cancer Res 41:3852-3856
-
(1981)
Cancer Res
, vol.41
, pp. 3852-3856
-
-
Haskill, J.S.1
-
44
-
-
21544452747
-
+ monocytes
-
DOI 10.1161/01.ATV.0000168410.44722.86
-
Methe H, Kim JO, Kofler S et al (2005) Statins decrease toll-like receptor 4 expression and downstream signaling in human CD14+ monocytes. Arterioscler Thromb Vasc Biol 25:1439-1445 (Pubitemid 40923365)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.7
, pp. 1439-1445
-
-
Methe, H.1
Kim, J.-O.2
Kofler, S.3
Nabauer, M.4
Weis, M.5
-
45
-
-
79952021934
-
Innate immunity in the adult mammalian heart: For whom the cell tolls
-
discussion 50-31
-
Mann DL, Topkara VK, Evans S, Barger PM (2010) Innate immunity in the adult mammalian heart: for whom the cell tolls. Trans Am Clin Climatol Assoc 121:34-50; discussion 50-31
-
(2010)
Trans Am Clin Climatol Assoc
, vol.121
, pp. 34-50
-
-
Mann, D.L.1
Topkara, V.K.2
Evans, S.3
Barger, P.M.4
-
46
-
-
34948820602
-
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
-
DOI 10.1038/nm1622, PII NM1622
-
Apetoh L, Ghiringhelli F, Tesniere A et al (2007) Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 13:1050-1059 (Pubitemid 47517504)
-
(2007)
Nature Medicine
, vol.13
, Issue.9
, pp. 1050-1059
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
Obeid, M.4
Ortiz, C.5
Criollo, A.6
Mignot, G.7
Maiuri, M.C.8
Ullrich, E.9
Saulnier, P.10
Yang, H.11
Amigorena, S.12
Ryffel, B.13
Barrat, F.J.14
Saftig, P.15
Levi, F.16
Lidereau, R.17
Nogues, C.18
Mira, J.-P.19
Chompret, A.20
Joulin, V.21
Clavel-Chapelon, F.22
Bourhis, J.23
Andre, F.24
Delaloge, S.25
Tursz, T.26
Kroemer, G.27
Zitvogel, L.28
more..
-
47
-
-
49249127841
-
Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies
-
Apetoh L, Tesniere A, Ghiringhelli F et al (2008) Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies. Cancer Res 68:4026-4030
-
(2008)
Cancer Res
, vol.68
, pp. 4026-4030
-
-
Apetoh, L.1
Tesniere, A.2
Ghiringhelli, F.3
-
48
-
-
34250795110
-
Doxorubicin cardiomyopathy via TLR-2 stimulation: Potential for prevention using current anti-retroviral inhibitors such as ritonavir and nelfinavir
-
DOI 10.1002/hon.811
-
Kast RE, Foley KF, Focosi D (2007) Doxorubicin cardiomyopathy via TLR-2 stimulation: potential for prevention using current anti-retroviral inhibitors such as ritonavir and nelfinavir. Hematol Oncol 25:96-97 (Pubitemid 46972837)
-
(2007)
Hematological Oncology
, vol.25
, Issue.2
, pp. 96-97
-
-
Kast, R.E.1
Foley, K.F.2
Focosi, D.3
-
49
-
-
19644390754
-
Expansion of circulating toll-like receptor 4-positive monocytes in patients with acute coronary syndrome
-
DOI 10.1161/CIRCULATIONAHA.104.498865
-
Methe H, Kim JO, Kofler S et al (2005) Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome. Circulation 111:2654-2661 (Pubitemid 40740866)
-
(2005)
Circulation
, vol.111
, Issue.20
, pp. 2654-2661
-
-
Methe, H.1
Kim, J.-O.2
Kofler, S.3
Weis, M.4
Nabauer, M.5
Koglin, J.6
-
50
-
-
8144229686
-
Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice
-
DOI 10.1161/01.CIR.0000146889.46519.27
-
Nozaki N, Shishido T, Takeishi Y, Kubota I (2004) Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice. Circulation 110:2869-2874 (Pubitemid 39473611)
-
(2004)
Circulation
, vol.110
, Issue.18
, pp. 2869-2874
-
-
Nozaki, N.1
Shishido, T.2
Takeishi, Y.3
Kubota, I.4
-
51
-
-
40449124041
-
Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice
-
Riad A, Bien S, Gratz M et al (2008) Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice. Eur J Heart Fail 10:233-243
-
(2008)
Eur J Heart Fail
, vol.10
, pp. 233-243
-
-
Riad, A.1
Bien, S.2
Gratz, M.3
-
52
-
-
33846204374
-
Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury
-
DOI 10.1152/ajpheart.00642.2006
-
Sakata Y, Dong JW, Vallejo JG et al (2007) Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 292:H503-H509 (Pubitemid 46105213)
-
(2007)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.292
, Issue.1
-
-
Sakata, Y.1
Dong, J.-W.2
Vallejo, J.G.3
Huang, C.-H.4
Baker, J.S.5
Tracey, K.J.6
Tacheuchi, O.7
Akira, S.8
Mann, D.L.9
-
53
-
-
0345599171
-
Toll-Like Receptor-2 Modulates Ventricular Remodeling after Myocardial Infarction
-
DOI 10.1161/01.CIR.0000101921.93016.1C
-
Shishido T, Nozaki N, Yamaguchi S et al (2003) Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction. Circulation 108:2905-2910 (Pubitemid 37517819)
-
(2003)
Circulation
, vol.108
, Issue.23
, pp. 2905-2910
-
-
Shishido, T.1
Nozaki, N.2
Yamaguchi, S.3
Shibata, Y.4
Nitobe, J.5
Miyamoto, T.6
Takahashi, H.7
Arimoto, T.8
Maeda, K.9
Yamakawa, M.10
Takeuchi, O.11
Akira, S.12
Takeishi, Y.13
Kubota, I.14
-
54
-
-
11244310637
-
Viruses as adjuvants for autoimmunity: Evidence from Coxsackievirus- induced myocarditis
-
DOI 10.1002/rmv.445
-
Fairweather D, Frisancho-Kiss S, Rose NR (2005) Viruses as adjuvants for autoimmunity: evidence from Coxsackievirus-induced myocarditis. Rev Med Virol 15:17-27 (Pubitemid 40070040)
-
(2005)
Reviews in Medical Virology
, vol.15
, Issue.1
, pp. 17-27
-
-
Fairweather, D.1
Frisancho-Kiss, S.2
Rose, N.R.3
-
55
-
-
77955277971
-
Recombinant human interleukin-1 receptor antagonist protects mice against acute doxorubicin-induced cardiotoxicity
-
Zhu J, Zhang J, Xiang D et al (2010) Recombinant human interleukin-1 receptor antagonist protects mice against acute doxorubicin-induced cardiotoxicity. Eur J Pharmacol 643:247-253
-
(2010)
Eur J Pharmacol
, vol.643
, pp. 247-253
-
-
Zhu, J.1
Zhang, J.2
Xiang, D.3
-
56
-
-
0035895913
-
Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes
-
Frantz S, Kelly RA, Bourcier T (2001) Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes. J Biol Chem 276:5197-5203
-
(2001)
J Biol Chem
, vol.276
, pp. 5197-5203
-
-
Frantz, S.1
Kelly, R.A.2
Bourcier, T.3
-
57
-
-
0036845841
-
Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: The role of hydrogen peroxide
-
DOI 10.1042/BJ20020752
-
Wang S, Kotamraju S, Konorev E et al (2002) Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide. Biochem J 367:729-740 (Pubitemid 35305712)
-
(2002)
Biochemical Journal
, vol.367
, Issue.3
, pp. 729-740
-
-
Wang, S.1
Kotamraju, S.2
Konorev, E.3
Kalivendi, S.4
Joseph, J.5
Kalyanaraman, B.6
-
58
-
-
41149165830
-
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction
-
DOI 10.1161/CIRCRESAHA.107.158220
-
Timmers L, Sluijter JP, Keulen JK van et al (2008) Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Circ Res 102:257-264 (Pubitemid 351674064)
-
(2008)
Circulation Research
, vol.102
, Issue.2
, pp. 257-264
-
-
Timmers, L.1
Sluijter, J.P.G.2
Van Keulen, J.K.3
Hoefer, I.E.4
Nederhoff, M.G.J.5
Goumans, M.-J.6
Doevendans, P.A.7
Van Echteld, C.J.A.8
Joles, J.A.9
Quax, P.H.10
Piek, J.J.11
Pasterkamp, G.12
De Kleijn, D.P.V.13
-
59
-
-
0037465251
-
The interleukin-1 receptor/toll-like receptor superfamily: Signal transduction during inflammation and host defense
-
Dunne A, O'Neill LA (2003) The interleukin-1 receptor/toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci STKE 2003:re3
-
(2003)
Sci STKE
, vol.2003
-
-
Dunne, A.1
O'Neill, L.A.2
-
60
-
-
35348847091
-
Persistent alterations to the gene expression profile of the heart subsequent to chronic doxorubicin treatment
-
DOI 10.1007/s12012-007-0026-0
-
Berthiaume JM, Wallace KB (2007) Persistent alterations to the gene expression profile of the heart subsequent to chronic Doxorubicin treatment. Cardiovasc Toxicol 7:178-191 (Pubitemid 47575003)
-
(2007)
Cardiovascular Toxicology
, vol.7
, Issue.3
, pp. 178-191
-
-
Berthiaume, J.M.1
Wallace, K.B.2
-
61
-
-
0031974196
-
Use of cardiac troponin T levels as an indicator of doxorubicin-induced cardiotoxicity
-
Herman EH, Lipshultz SE, Rifai N et al (1998) Use of cardiac troponin T levels as an indicator of doxorubicin-induced cardiotoxicity. Cancer Res 58:195-197 (Pubitemid 28047052)
-
(1998)
Cancer Research
, vol.58
, Issue.2
, pp. 195-197
-
-
Herman, E.H.1
Lipshultz, S.E.2
Rifai, N.3
Zhang, J.4
Papoian, T.5
Yu, Z.-X.6
Takeda, K.7
Ferrans, V.J.8
-
62
-
-
0032895183
-
TAFII250 Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin
-
Saadane N, Alpert L, Chalifour LE (1999) TAFII250, egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin. Am J Physiol 276:H803-H814 (Pubitemid 29157451)
-
(1999)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.276
, Issue.3
-
-
Saadane, N.1
Alpert, L.2
Chalifour, L.E.3
-
63
-
-
0030931797
-
A novel cardiac-restricted target for doxorubicin. CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes
-
DOI 10.1074/jbc.272.36.22800
-
Jeyaseelan R, Poizat C, Baker RK et al (1997) A novel cardiac-restricted target for doxorubicin. CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes. J Biol Chem 272:22800-22808 (Pubitemid 27386100)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.36
, pp. 22800-22808
-
-
Jeyaseelan, R.1
Poizat, C.2
Baker, R.K.3
Abdishoo, S.4
Isterabadi, L.B.5
Lyons, G.E.6
Kedes, L.7
-
64
-
-
70449529313
-
Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats
-
Zordoky BN, Anwar-Mohamed A, Aboutabl ME, El-Kadi AO (2010) Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats. Toxicol Appl Pharmacol 242:38-46
-
(2010)
Toxicol Appl Pharmacol
, vol.242
, pp. 38-46
-
-
Zordoky, B.N.1
Anwar-Mohamed, A.2
Aboutabl, M.E.3
El-Kadi, A.O.4
-
65
-
-
77953806921
-
Inhibition of gene expression of heart fatty acid binding protein and organic cation/carnitine transporter in doxorubicin cardiomyopathic rat model
-
Sayed-Ahmed MM, Al-Shabanah OA, Hafez MM et al (2010) Inhibition of gene expression of heart fatty acid binding protein and organic cation/carnitine transporter in doxorubicin cardiomyopathic rat model. Eur J Pharmacol 640:143-149
-
(2010)
Eur J Pharmacol
, vol.640
, pp. 143-149
-
-
Sayed-Ahmed, M.M.1
Al-Shabanah, O.A.2
Hafez, M.M.3
-
66
-
-
77958601786
-
Doxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activation
-
Pointon AV, Walker TM, Phillips KM et al (2010) Doxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activation. PLoS One 5:e12733
-
(2010)
PLoS One
, vol.5
-
-
Pointon, A.V.1
Walker, T.M.2
Phillips, K.M.3
-
67
-
-
0031845978
-
Doxorubicin cardiotoxicity: Diastolic cardiac myocyte dysfunction as a result of impaired calcium handling in isolated cardiac myocytes
-
Maeda A, Honda M, Kuramochi T, Takabatake T (1998) Doxorubicin cardiotoxicity: diastolic cardiac myocyte dysfunction as a result of impaired calcium handling in isolated cardiac myocytes. Jpn Circ J 62:505-511
-
(1998)
Jpn Circ J
, vol.62
, pp. 505-511
-
-
Maeda, A.1
Honda, M.2
Kuramochi, T.3
Takabatake, T.4
-
68
-
-
0031047983
-
Molecular mechanisms of doxorubicin-induced cardiomyopathy. Selective suppression of Reiske iron-sulfur protein, ADP/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes
-
DOI 10.1074/jbc.272.9.5828
-
Jeyaseelan R, Poizat C, Wu HY, Kedes L (1997) Molecular mechanisms of doxorubicin-induced cardiomyopathy. Selective suppression of reiske iron-sulfur protein, ADP/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes. J Biol Chem 272:5828-5832 (Pubitemid 27102415)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.9
, pp. 5828-5832
-
-
Jeyaseelan, R.1
Poizat, C.2
Wu, H.-Y.3
Kedes, L.4
-
69
-
-
0032005833
-
Sarcoplasmic reticulum genes are selectively down-regulated in cardiomyopathy produced by doxorubicin in rabbits
-
DOI 10.1006/jmcc.1997.0588
-
Arai M, Tomaru K, Takizawa T et al (1998) Sarcoplasmic reticulum genes are selectively down-regulated in cardiomyopathy produced by doxorubicin in rabbits. J Mol Cell Cardiol 30:243-254 (Pubitemid 28116304)
-
(1998)
Journal of Molecular and Cellular Cardiology
, vol.30
, Issue.2
, pp. 243-254
-
-
Arai, M.1
Tomaru, K.2
Takizawa, T.3
Sekiguchi, K.4
Yokoyama, T.5
Suzuki, T.6
Nagai, R.7
-
70
-
-
40549128682
-
Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage
-
DOI 10.1111/j.1474-9726.2007.00358.x
-
Maejima Y, Adachi S, Ito H et al (2008) Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage. Aging Cell 7:125-136 (Pubitemid 351359646)
-
(2008)
Aging Cell
, vol.7
, Issue.2
, pp. 125-136
-
-
Maejima, Y.1
Adachi, S.2
Ito, H.3
Hirao, K.4
Isobe, M.5
-
71
-
-
33947680221
-
The telomere-telomerase axis and the heart
-
Kajstura J, Rota M, Urbanek K et al (2006) The telomere-telomerase axis and the heart. Antioxid Redox Signal 8:2125-2141 (Pubitemid 46489636)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.11-12
, pp. 2125-2141
-
-
Kajstura, J.1
Rota, M.2
Urbanek, K.3
Hosoda, T.4
Bearzi, C.5
Anversa, P.6
Bolli, R.7
Leri, A.8
-
72
-
-
43249122323
-
The aging cardiomyocyte: A mini-review
-
DOI 10.1159/000113503
-
Bernhard D, Laufer G (2008) The aging cardiomyocyte: a mini-review. Gerontology 54:24-31 (Pubitemid 351650654)
-
(2008)
Gerontology
, vol.54
, Issue.1
, pp. 24-31
-
-
Bernhard, D.1
Laufer, G.2
-
73
-
-
45549108538
-
Protein quality control and degradation in cardiomyocytes
-
Wang X, Su H, Ranek MJ (2008) Protein quality control and degradation in cardiomyocytes. J Mol Cell Cardiol 45:11-27
-
(2008)
J Mol Cell Cardiol
, vol.45
, pp. 11-27
-
-
Wang, X.1
Su, H.2
Ranek, M.J.3
-
74
-
-
72549092827
-
Activation of the ubiquitin-proteasome system in doxorubicin cardiomyopathy
-
Ranek MJ, Wang X (2009) Activation of the ubiquitin-proteasome system in doxorubicin cardiomyopathy. Curr Hypertens Rep 11:389-395
-
(2009)
Curr Hypertens Rep
, vol.11
, pp. 389-395
-
-
Ranek, M.J.1
Wang, X.2
-
75
-
-
33845638625
-
Heart failure and protein quality control
-
DOI 10.1161/01.RES.0000252342.61447.a2, PII 0000301220061222000007
-
Wang X, Robbins J (2006) Heart failure and protein quality control. Circ Res 99:1315-1328 (Pubitemid 44949667)
-
(2006)
Circulation Research
, vol.99
, Issue.12
, pp. 1315-1328
-
-
Wang, X.1
Robbins, J.2
-
76
-
-
34147131267
-
The bitter end: The ubiquitin-proteasome system and cardiac dysfunction
-
DOI 10.1161/CIRCULATIONAHA.106.649863, PII 0000301720070320000019
-
Patterson C, Ike C, Willis PWT et al (2007) The bitter end: the ubiquitin-proteasome system and cardiac dysfunction. Circulation 115:1456-1463 (Pubitemid 46648383)
-
(2007)
Circulation
, vol.115
, Issue.11
, pp. 1456-1463
-
-
Patterson, C.1
Ike, C.2
Willis IV, P.W.3
Stouffer, G.A.4
Willis, M.S.5
-
77
-
-
35649014889
-
Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p
-
DOI 10.1073/pnas.0701369104
-
Tu D, Li W, Ye Y, Brunger AT (2007) Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p. Proc Natl Acad Sci U S A 104:15599-15606 (Pubitemid 350035351)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.40
, pp. 15599-15606
-
-
Tu, D.1
Li, W.2
Ye, Y.3
Brunger, A.T.4
-
78
-
-
33745726659
-
The ubiquitin-proteasome system in cardiac physiology and pathology
-
Powell SR (2006) The ubiquitin-proteasome system in cardiac physiology and pathology. Am J Physiol Heart Circ Physiol 291:H1-H19
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Powell, S.R.1
-
79
-
-
0035072229
-
Degradation of oxidized proteins by the 20S proteasome
-
Davies KJ (2001) Degradation of oxidized proteins by the 20S proteasome. Biochimie 83:301-310
-
(2001)
Biochimie
, vol.83
, pp. 301-310
-
-
Davies, K.J.1
-
80
-
-
57349171307
-
A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome
-
Liu J, Zheng H, Tang M et al (2008) A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome. Am J Physiol Heart Circ Physiol 295:H2541-2550
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Liu, J.1
Zheng, H.2
Tang, M.3
-
81
-
-
37849029183
-
P53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC
-
Li YZ, Lu DY, Tan WQ et al (2008) p53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC. Mol Cell Biol 28:564-574
-
(2008)
Mol Cell Biol
, vol.28
, pp. 564-574
-
-
Li, Y.Z.1
Lu, D.Y.2
Tan, W.Q.3
-
82
-
-
34247094793
-
The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: Identification of a degradation-resistant mutant
-
DOI 10.1074/jbc.M609186200
-
Nam YJ, Mani K, Wu L et al (2007) The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: identification of a degradation-resistant mutant. J Biol Chem 282:5522-5528 (Pubitemid 47093727)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.8
, pp. 5522-5528
-
-
Nam, Y.-J.1
Mani, K.2
Wu, L.3
Peng, C.-F.4
Calvert, J.W.5
Foo, R.S.-Y.6
Krishnamurthy, B.7
Miao, W.8
Ashton, A.W.9
Lefer, D.J.10
Kitsis, R.N.11
-
83
-
-
0035797846
-
Length dependence of tension generation in rat skinned cardiac muscle: Role of titin in the Frank-Starling mechanism of the heart
-
Fukuda N, Sasaki D, Ishiwata S, Kurihara S (2001) Length dependence of tension generation in rat skinned cardiac muscle: role of titin in the frank-starling mechanism of the heart. Circulation 104:1639-1645 (Pubitemid 32947527)
-
(2001)
Circulation
, vol.104
, Issue.14
, pp. 1639-1645
-
-
Fukuda, N.1
Sasaki, D.2
Ishiwata, S.3
Kurihara, S.4
-
84
-
-
1542349778
-
Anthracyclines Induce Calpain-dependent Titin Proteolysis and Necrosis in Cardiomyocytes
-
DOI 10.1074/jbc.M308033200
-
Lim CC, Zuppinger C, Guo X et al (2004) Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes. J Biol Chem 279:8290-8299 (Pubitemid 38294721)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.9
, pp. 8290-8299
-
-
Lim, C.C.1
Zuppinger, C.2
Guo, X.3
Kuster, G.M.4
Helmes, M.5
Eppenberger, H.M.6
Suter, T.M.7
Liao, R.8
Sawyer, D.B.9
-
85
-
-
0037446892
-
Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth
-
DOI 10.1073/pnas.0835895100
-
Haq S, Michael A, Andreucci M et al (2003) Stabilization of beta-catenin by a wnt-independent mechanism regulates cardiomyocyte growth. Proc Natl Acad Sci U S A 100:4610-4615 (Pubitemid 36457778)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.8
, pp. 4610-4615
-
-
Haq, S.1
Michael, A.2
Andreucci, M.3
Bhattacharya, K.4
Dotto, P.5
Walters, B.6
Woodgett, J.7
Kilter, H.8
Force, T.9
-
86
-
-
0034460132
-
Proteasome-mediated degradation of the coactivator p300 impairs cardiac transcription
-
DOI 10.1128/MCB.20.23.8643-8654.2000
-
Poizat C, Sartorelli V, Chung G et al (2000) Proteasome-mediated degradation of the coactivator p300 impairs cardiac transcription. Mol Cell Biol 20:8643-8654 (Pubitemid 32245898)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.23
, pp. 8643-8654
-
-
Poizat, C.1
Sartorelli, V.2
Chung, G.3
Kloner, R.A.4
Kedes, L.5
-
87
-
-
0034936463
-
GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex
-
Li Q, Sanlioglu S, Li S et al (2001) GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex. Antioxid Redox Signal 3:415-432 (Pubitemid 32646033)
-
(2001)
Antioxidants and Redox Signaling
, vol.3
, Issue.3
, pp. 415-432
-
-
Li, Q.1
Sanlioglu, S.2
Li, S.3
Ritchie, T.4
Oberley, L.5
Engelhardt, J.F.6
-
88
-
-
45849106068
-
Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes
-
DOI 10.1093/cvr/cvn076
-
Yamamoto Y, Hoshino Y, Ito T et al (2008) Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes. Cardiovasc Res 79:89-96 (Pubitemid 351881941)
-
(2008)
Cardiovascular Research
, vol.79
, Issue.1
, pp. 89-96
-
-
Yamamoto, Y.1
Hoshino, Y.2
Ito, T.3
Nariai, T.4
Mohri, T.5
Obana, M.6
Hayata, N.7
Uozumi, Y.8
Maeda, M.9
Fujio, Y.10
Azuma, J.11
-
89
-
-
65549097264
-
Atrogin-1/MAFbx enhances simulated ischemia/reperfusion-induced apoptosis in cardiomyocytes through degradation of MAPK phosphatase-1 and sustained JNK activation
-
Xie P, Guo S, Fan Y et al (2009) Atrogin-1/MAFbx enhances simulated ischemia/reperfusion-induced apoptosis in cardiomyocytes through degradation of MAPK phosphatase-1 and sustained JNK activation. J Biol Chem 284:5488-5496
-
(2009)
J Biol Chem
, vol.284
, pp. 5488-5496
-
-
Xie, P.1
Guo, S.2
Fan, Y.3
-
90
-
-
0035807969
-
Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy
-
DOI 10.1073/pnas.251541198
-
Gomes MD, Lecker SH, Jagoe RT et al (2001) Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy. Proc Natl Acad Sci U S A 98:14440-14445 (Pubitemid 33121410)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.25
, pp. 14440-14445
-
-
Gomes, M.D.1
Lecker, S.H.2
Jagoe, R.T.3
Navon, A.4
Goldberg, A.L.5
-
91
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
DOI 10.1016/S1097-2765(04)00211-4, PII S1097276504002114
-
Stitt TN, Drujan D, Clarke BA et al (2004) The IGF-1/PI3 K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 14:395-403 (Pubitemid 38591410)
-
(2004)
Molecular Cell
, vol.14
, Issue.3
, pp. 395-403
-
-
Stitt, T.N.1
Drujan, D.2
Clarke, B.A.3
Panaro, F.4
Timofeyva, Y.5
Kline, W.O.6
Gonzalez, M.7
Yancopoulos, G.D.8
Glass, D.J.9
-
92
-
-
33344473389
-
Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart
-
DOI 10.1016/j.bbrc.2006.01.163, PII S0006291X06002580
-
Razeghi P, Baskin KK, Sharma S et al (2006) Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart. Biochem Biophys Res Commun 342:361-364 (Pubitemid 43289002)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.342
, Issue.2
, pp. 361-364
-
-
Razeghi, P.1
Baskin, K.K.2
Sharma, S.3
Young, M.E.4
Stepkowski, S.5
Faadiel, E.M.6
Taegtmeyer, H.7
-
93
-
-
33845638292
-
Hypertrophy and atrophy of the heart: The other side of remodeling
-
DOI 10.1196/annals.1380.011, Interactive and Integrative Cardiology
-
Razeghi P, Taegtmeyer H (2006) Hypertrophy and atrophy of the heart: the other side of remodeling. Ann N Y Acad Sci 1080:110-119 (Pubitemid 44955417)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1080
, pp. 110-119
-
-
Razeghi, P.1
Taegtmeyer, H.2
-
94
-
-
9644270401
-
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex
-
DOI 10.1172/JCI200422220
-
Li HH, Kedar V, Zhang C et al (2004) Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex. J Clin Invest 114:1058-1071 (Pubitemid 39578695)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.8
, pp. 1058-1071
-
-
Li, H.-H.1
Kedar, V.2
Zhang, C.3
McDonough, H.4
Arya, R.5
Wang, D.-Z.6
Patterson, C.7
-
95
-
-
0035941020
-
Identification of ubiquitin ligases required for skeletal Muscle Atrophy
-
DOI 10.1126/science.1065874
-
Bodine SC, Latres E, Baumhueter S et al (2001) Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294:1704-1708 (Pubitemid 33104839)
-
(2001)
Science
, vol.294
, Issue.5547
, pp. 1704-1708
-
-
Bodine, S.C.1
Latres, E.2
Baumhueter, S.3
Lai, V.K.-M.4
Nunez, L.5
Clarke, B.A.6
Poueymirou, W.T.7
Panaro, F.J.8
Erqian, N.9
Dharmarajan, K.10
Pan, Z.-Q.11
Valenzuela, D.M.12
Dechiara, T.M.13
Stitt, T.N.14
Yancopoulos, G.D.15
Glass, D.J.16
-
96
-
-
56449095862
-
The involvement of the ubiquitin proteasome system in human skeletal muscle remodelling and atrophy
-
Murton AJ, Constantin D, Greenhaff PL (2008) The involvement of the ubiquitin proteasome system in human skeletal muscle remodelling and atrophy. Biochim Biophys Acta 1782:730-743
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 730-743
-
-
Murton, A.J.1
Constantin, D.2
Greenhaff, P.L.3
-
97
-
-
22544466964
-
Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: Role of mitochondrial reactive oxygen species and calcium
-
DOI 10.1042/BJ20050285
-
Kalivendi SV, Konorev EA, Cunningham S et al (2005) Doxorubicin activates nuclear factor of activated T-lymphocytes and fas ligand transcription: role of mitochondrial reactive oxygen species and calcium. Biochem J 389:527-539 (Pubitemid 41021156)
-
(2005)
Biochemical Journal
, vol.389
, Issue.2
, pp. 527-539
-
-
Kalivendi, S.V.1
Konorev, E.A.2
Cunningham, S.3
Vanamala, S.K.4
Kaji, E.H.5
Joseph, J.6
Kalyanaraman, B.7
-
98
-
-
33847753121
-
Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes
-
DOI 10.1074/jbc.M609547200
-
Ito T, Fujio Y, Takahashi K, Azuma J (2007) Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes. J Biol Chem 282:1152-1160 (Pubitemid 47076570)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.2
, pp. 1152-1160
-
-
Ito, T.1
Fujio, Y.2
Takahashi, K.3
Azuma, J.4
-
99
-
-
63149192309
-
Involvement of transcriptional factor TonEBP in the regulation of the taurine transporter in the cardiomyocyte
-
Ito T, Fujio Y, Schaffer SW, Azuma J (2009) Involvement of transcriptional factor TonEBP in the regulation of the taurine transporter in the cardiomyocyte. Adv Exp Med Biol 643:523-532
-
(2009)
Adv Exp Med Biol
, vol.643
, pp. 523-532
-
-
Ito, T.1
Fujio, Y.2
Schaffer, S.W.3
Azuma, J.4
-
100
-
-
53149091626
-
A phase I pharmacodynamic trial of bortezomib in combination with doxorubicin in patients with advanced cancer
-
LoConte NK, Thomas JP, Alberti D et al (2008) A phase I pharmacodynamic trial of bortezomib in combination with doxorubicin in patients with advanced cancer. Cancer Chemother Pharmacol 63:109-115
-
(2008)
Cancer Chemother Pharmacol
, vol.63
, pp. 109-115
-
-
LoConte, N.K.1
Thomas, J.P.2
Alberti, D.3
-
101
-
-
0030919509
-
Neuregulins and their receptors: A versatile signaling module in organogenesis and oncogenesis
-
DOI 10.1016/S0896-6273(00)80324-4
-
Burden S, Yarden Y (1997) Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis. Neuron 18:847-855 (Pubitemid 27274603)
-
(1997)
Neuron
, vol.18
, Issue.6
, pp. 847-855
-
-
Burden, S.1
Yarden, Y.2
-
102
-
-
42349100068
-
Constitutive activation of c-jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas
-
Li JY, Wang H, May S et al (2008) Constitutive activation of c-jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas. J Neurooncol 88:11-17
-
(2008)
J Neurooncol
, vol.88
, pp. 11-17
-
-
Li, J.Y.1
Wang, H.2
May, S.3
-
103
-
-
7644236012
-
Multiple novel transcription initiation sites for NRG1
-
DOI 10.1016/j.gene.2004.07.029, PII S037811190400472X
-
Steinthorsdottir V, Stefansson H, Ghosh S et al (2004) Multiple novel transcription initiation sites for NRG1. Gene 342:97-105 (Pubitemid 39457182)
-
(2004)
Gene
, vol.342
, Issue.1
, pp. 97-105
-
-
Steinthorsdottir, V.1
Stefansson, H.2
Ghosh, S.3
Birgisdottir, B.4
Bjornsdottir, S.5
Fasquel, A.C.6
Olafsson, O.7
Stefansson, K.8
Gulcher, J.R.9
-
104
-
-
33847718214
-
The EGF receptor family: spearheading a merger of signaling and therapeutics
-
DOI 10.1016/j.ceb.2007.02.008, PII S0955067407000221
-
Bublil EM, Yarden Y (2007) The EGF receptor family: spearheading a merger of signaling and therapeutics. Curr Opin Cell Biol 19:124-134 (Pubitemid 46386405)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.2
, pp. 124-134
-
-
Bublil, E.M.1
Yarden, Y.2
-
105
-
-
77955891306
-
Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway
-
Horie T, Ono K, Nishi H et al (2010) Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway. Cardiovasc Res 87:656-664
-
(2010)
Cardiovasc Res
, vol.87
, pp. 656-664
-
-
Horie, T.1
Ono, K.2
Nishi, H.3
-
106
-
-
0032562770
-
Neuregulins promote survival and growth of cardiac myocytes: Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
-
DOI 10.1074/jbc.273.17.10261
-
Zhao YY, Sawyer DR, Baliga RR et al (1998) Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem 273:10261-10269 (Pubitemid 28227629)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.17
, pp. 10261-10269
-
-
Zhao, Y.-Y.1
Sawyer, D.R.2
Baliga, R.R.3
Opel, D.J.4
Han, X.5
Marchionni, M.A.6
Kelly, R.A.7
-
107
-
-
73349085919
-
Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancer
-
Spector NL, Blackwell KL (2009) Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol 27:5838-5847
-
(2009)
J Clin Oncol
, vol.27
, pp. 5838-5847
-
-
Spector, N.L.1
Blackwell, K.L.2
-
108
-
-
18644370411
-
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha
-
DOI 10.1016/S0092-8674(02)00940-6
-
Garrett TP, McKern NM, Lou M et al (2002) Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell 110:763-773 (Pubitemid 35283965)
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 763-773
-
-
Garrett, T.P.J.1
McKern, N.M.2
Lou, M.3
Elleman, T.C.4
Adams, T.E.5
Lovrecz, G.O.6
Zhu, H.-J.7
Walker, F.8
Frenkel, M.J.9
Hoyne, P.A.10
Jorissen, R.N.11
Nice, E.C.12
Burgess, A.W.13
Ward, C.W.14
-
109
-
-
34548132413
-
Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: Implications for therapy of heart failure
-
DOI 10.1161/CIRCULATIONAHA.107.690487, PII 0000301720070821000013
-
Lemmens K, Doggen K, De Keulenaer GW (2007) Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failure. Circulation 116:954-960 (Pubitemid 47300920)
-
(2007)
Circulation
, vol.116
, Issue.8
, pp. 954-960
-
-
Lemmens, K.1
Doggen, K.2
De Keulenaer, G.W.3
-
110
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
DOI 10.1126/science.1141478
-
Engelman JA, Zejnullahu K, Mitsudomi T et al (2007) MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316:1039-1043 (Pubitemid 46799492)
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Joon, O.P.6
Lindeman, N.7
Gale, C.-M.8
Zhao, X.9
Christensen, J.10
Kosaka, T.11
Holmes, A.J.12
Rogers, A.M.13
Cappuzzo, F.14
Mok, T.15
Lee, C.16
Johnson, B.E.17
Cantley, L.C.18
Janne, P.A.19
-
111
-
-
33751328082
-
ErbB receptors: new insights on mechanisms and biology
-
DOI 10.1016/j.tcb.2006.10.008, PII S0962892406002959
-
Linggi B, Carpenter G (2006) ErbB receptors: new insights on mechanisms and biology. Trends Cell Biol 16:649-656 (Pubitemid 44809890)
-
(2006)
Trends in Cell Biology
, vol.16
, Issue.12
, pp. 649-656
-
-
Linggi, B.1
Carpenter, G.2
-
113
-
-
0037172982
-
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
-
DOI 10.1073/pnas.122249299
-
Ozcelik C, Erdmann B, Pilz B et al (2002) Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci U S A 99:8880-8885 (Pubitemid 34693652)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8880-8885
-
-
Ozcelik, C.1
Erdmann, B.2
Pilz, B.3
Wettschureck, N.4
Britsch, S.5
Hubner, N.6
Chien, K.R.7
Birchmeier, C.8
Garratt, A.N.9
-
114
-
-
0036099675
-
ErbB2 is essential in the prevention of dilated cardiomyopathy
-
DOI 10.1038/nm0502-459
-
Crone SA, Zhao YY, Fan L et al (2002) ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med 8:459-465 (Pubitemid 34546747)
-
(2002)
Nature Medicine
, vol.8
, Issue.5
, pp. 459-465
-
-
Crone, S.A.1
Zhao, Y.-Y.2
Fan, L.3
Gu, Y.4
Minamisawa, S.5
Liu, Y.6
Peterson, K.L.7
Chen, J.8
Kahn, R.9
Condorelli, G.10
Ross Jr., J.11
Chien, K.R.12
Lee, K.-F.13
-
115
-
-
0037007076
-
Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: Potential mechanism for trastuzumab-induced cardiotoxicity
-
DOI 10.1161/01.CIR.0000013839.41224.1C
-
Sawyer DB, Zuppinger C, Miller TA et al (2002) Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity. Circulation 105:1551-1554 (Pubitemid 34297631)
-
(2002)
Circulation
, vol.105
, Issue.13
, pp. 1551-1554
-
-
Sawyer, D.B.1
Zuppinger, C.2
Miller, T.A.3
Eppenberger, H.M.4
Suter, T.M.5
-
116
-
-
63049089461
-
Inhibition of ErbB2 by receptor tyrosine kinase inhibitors causes myofibrillar structural damage without cell death in adult rat cardiomyocytes
-
Pentassuglia L, Graf M, Lane H et al (2009) Inhibition of ErbB2 by receptor tyrosine kinase inhibitors causes myofibrillar structural damage without cell death in adult rat cardiomyocytes. Exp Cell Res 315:1302-1312
-
(2009)
Exp Cell Res
, vol.315
, pp. 1302-1312
-
-
Pentassuglia, L.1
Graf, M.2
Lane, H.3
-
117
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against her2 for metastatic breast cancer that overexpresses HER2
-
DOI 10.1056/NEJM200103153441101
-
Slamon DJ, Leyland-Jones B, Shak S et al (2001) Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344:783-792 (Pubitemid 32222155)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
118
-
-
61349090481
-
Trastuzumab combined with pegylated liposomal doxorubicin in patients with metastatic breast cancer. Phase II Study of the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation
-
Christodoulou C, Kostopoulos I, Kalofonos HP et al (2009) Trastuzumab combined with pegylated liposomal doxorubicin in patients with metastatic breast cancer. phase II Study of the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation. the International Society for Cellular 76:275-285
-
(2009)
The International Society for Cellular
, vol.76
, pp. 275-285
-
-
Christodoulou, C.1
Kostopoulos, I.2
Kalofonos, H.P.3
-
119
-
-
50849096058
-
Anthracycline-trastuzumab regimens for HER2/neu-overexpressing breast cancer: Current experience and future strategies
-
Rayson D, Richel D, Chia S et al (2008) Anthracycline-trastuzumab regimens for HER2/neu-overexpressing breast cancer: current experience and future strategies. Ann Oncol 19:1530-1539
-
(2008)
Ann Oncol
, vol.19
, pp. 1530-1539
-
-
Rayson, D.1
Richel, D.2
Chia, S.3
-
120
-
-
32144448027
-
Reversibility of trastuzumab-related cardiotoxicity: New insights based on clinical course and response to medical treatment
-
DOI 10.1200/JCO.2005.13.300
-
Ewer MS, Vooletich MT, Durand JB et al (2005) Reversibility of trastuzumab-related cardiotoxicity: new insights based on clinical course and response to medical treatment. J Clin Oncol 23:7820-7826 (Pubitemid 46657379)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.31
, pp. 7820-7826
-
-
Ewer, M.S.1
Vooletich, M.T.2
Durand, J.-B.3
Woods, M.L.4
Davis, J.R.5
Valero, V.6
Lenihan, D.J.7
-
121
-
-
22544475191
-
Heterozygous knockout of neuregulin-1 gene in mice exacerbates doxorubicin-induced heart failure
-
DOI 10.1152/ajpheart.00268.2005
-
Liu FF, Stone JR, Schuldt AJ et al (2005) Heterozygous knockout of neuregulin-1 gene in mice exacerbates doxorubicin-induced heart failure. Am J Physiol Heart Circ Physiol 289:H660-H666 (Pubitemid 41129381)
-
(2005)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.289
, Issue.2
-
-
Liu, F.-F.1
Stone, J.R.2
Schuldt, A.J.T.3
Okoshi, K.4
Okoshi, M.P.5
Nakayama, M.6
Ho, K.K.L.7
Manning, W.J.8
Marchionni, M.A.9
Lorell, B.H.10
Morgan, J.P.11
Yan, X.12
-
122
-
-
72249094133
-
Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins
-
Bian Y, Sun M, Silver M et al (2009) Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins. Am J Physiol Heart Circ Physiol 297:H1974-H1983
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Bian, Y.1
Sun, M.2
Silver, M.3
-
125
-
-
74949138296
-
Anthracycline cardiomyopathy is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell function
-
De Angelis A, Piegari E, Cappetta D et al (2010) Anthracycline cardiomyopathy is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell function. Circulation 121:276-292
-
(2010)
Circulation
, vol.121
, pp. 276-292
-
-
De Angelis, A.1
Piegari, E.2
Cappetta, D.3
-
126
-
-
76649144813
-
Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice
-
Huang C, Zhang X, Ramil JM et al (2010) Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice. Circulation 121:675-683
-
(2010)
Circulation
, vol.121
, pp. 675-683
-
-
Huang, C.1
Zhang, X.2
Ramil, J.M.3
-
127
-
-
77950555289
-
Adriamycin nephropathy: A failure of endothelial progenitor cell-induced repair
-
Yasuda K, Park HC, Ratliff B et al (2010) Adriamycin nephropathy: a failure of endothelial progenitor cell-induced repair. Am J Pathol 176:1685-1695
-
(2010)
Am J Pathol
, vol.176
, pp. 1685-1695
-
-
Yasuda, K.1
Park, H.C.2
Ratliff, B.3
-
128
-
-
12344334433
-
Angiopoietin-1 inhibits doxorubicin-induced human umbilical vein endothelial cell death by modulating fas expression and via the P13K/Akt pathway
-
DOI 10.1080/10623320490904115
-
Yin D, Li C, Kao RL et al (2004) Angiopoietin-1 inhibits doxorubicin-induced human umbilical vein endothelial cell death by modulating fas expression and via the PI3 K/Akt pathway. Endothelium 11:247-252 (Pubitemid 40123392)
-
(2004)
Endothelium: Journal of Endothelial Cell Research
, vol.11
, Issue.5-6
, pp. 247-252
-
-
Yin, D.1
Li, C.2
Kao, R.L.3
Ha, T.4
Krishnaswamy, G.5
Fitzgerald, M.6
Stuart, C.A.7
-
129
-
-
77957306355
-
Cardiotoxicity of anticancer treatments: What the cardiologist needs to know
-
Ewer MS, Ewer SM (2010) Cardiotoxicity of anticancer treatments: what the cardiologist needs to know. Nat Rev Cardiol 7:564-575
-
(2010)
Nat Rev Cardiol
, vol.7
, pp. 564-575
-
-
Ewer, M.S.1
Ewer, S.M.2
-
130
-
-
33847096349
-
Doxorubicin-Induced Cardiomyopathy. From the Cardiotoxic Mechanisms to Management
-
DOI 10.1016/j.pcad.2006.10.002, PII S0033062006001204
-
Takemura G, Fujiwara H (2007) Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management. Prog Cardiovasc Dis 49:330-352 (Pubitemid 46295436)
-
(2007)
Progress in Cardiovascular Diseases
, vol.49
, Issue.5
, pp. 330-352
-
-
Takemura, G.1
Fujiwara, H.2
-
131
-
-
41149115636
-
Anthracycline associated cardiotoxicity in survivors of childhood cancer
-
DOI 10.1136/hrt.2007.136093
-
Lipshultz SE, Alvarez JA, Scully RE (2008) Anthracycline associated cardiotoxicity in survivors of childhood cancer. Heart 94:525-533 (Pubitemid 351441417)
-
(2008)
Heart
, vol.94
, Issue.4
, pp. 525-533
-
-
Lipshultz, S.E.1
Alvarez, J.A.2
Scully, R.E.3
-
132
-
-
4544228968
-
Carvedilol prevents doxorubicin-induced free radical release and apoptosis in cardiomyocytes in vitro
-
DOI 10.1016/j.yjmcc.2004.05.024, PII S0022282804001658
-
Spallarossa P, Garibaldi S, Altieri P et al (2004) Carvedilol prevents doxorubicin-induced free radical release and apoptosis in cardiomyocytes in vitro. J Mol Cell Cardiol 37:837-846 (Pubitemid 39222076)
-
(2004)
Journal of Molecular and Cellular Cardiology
, vol.37
, Issue.4
, pp. 837-846
-
-
Spallarossa, P.1
Garibaldi, S.2
Altieri, P.3
Fabbi, P.4
Manca, V.5
Nasti, S.6
Rossettin, P.7
Ghigliotti, G.8
Ballestrero, A.9
Patrone, F.10
Barsotti, A.11
Brunelli, C.12
-
133
-
-
40749147609
-
Canadian Cardiovascular Society Consensus conference guidelines on heart failure - 2008 update: Best practices for the transition of care of heart failure patients, and the recognition, investigation and treatment of cardiomyopathies
-
Malcom J, Arnold O, Howlett JG et al (2008) Canadian Cardiovascular Society Consensus Conference guidelines on heart failure-2008 update: best practices for the transition of care of heart failure patients, and the recognition, investigation and treatment of cardiomyopathies. Can J Cardiol 24:21-40 (Pubitemid 351385400)
-
(2008)
Canadian Journal of Cardiology
, vol.24
, Issue.1
, pp. 21-40
-
-
Arnold, J.M.O.1
Howlett, J.G.2
Ducharme, A.3
Ezekowitz, J.A.4
Gardner, M.J.5
Giannetti, N.6
Haddad, H.7
Heckman, G.A.8
Isaac, D.9
Jong, P.10
Liu, P.11
Mann, E.12
McKelvie, R.S.13
Moe, G.W.14
Svendsen, A.M.15
Tsuyuki, R.T.16
O'Halloran, K.17
Ross, H.J.18
Sequeira, E.J.19
White, M.20
more..
-
134
-
-
0028831937
-
Efficacy and safety of metoprolol in the treatment of doxorubicin-induced cardiomyopathy in pediatric patients
-
Shaddy RE, Olsen SL, Bristow MR et al (1995) Efficacy and safety of metoprolol in the treatment of doxorubicin-induced cardiomyopathy in pediatric patients. Am Heart J 129:197-199
-
Am Heart J
, vol.129
, pp. 197-199
-
-
Shaddy, R.E.1
Olsen, S.L.2
Bristow, M.R.3
-
135
-
-
79960394760
-
Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function
-
Hiona A, Lee AS, Nagendran J et al (2010) Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function. J Thorac Cardiovasc Surg
-
(2010)
J Thorac Cardiovasc Surg
-
-
Hiona, A.1
Lee, A.S.2
Nagendran, J.3
-
136
-
-
61449181080
-
ACE inhibition and protection from doxorubicin-induced cardiotoxicity in the rat
-
Sacco G, Mario B, Lopez G et al (2009) ACE inhibition and protection from doxorubicin-induced cardiotoxicity in the rat. Vascul Pharmacol 50:166-170
-
(2009)
Vascul Pharmacol
, vol.50
, pp. 166-170
-
-
Sacco, G.1
Mario, B.2
Lopez, G.3
-
137
-
-
58149335531
-
American Society of Clinical Oncology 2008 clinical practice guideline update: Use of chemotherapy and radiation therapy protectants
-
Hensley ML, Hagerty KL, Kewalramani T et al (2009) American Society of Clinical Oncology 2008 clinical practice guideline update: use of chemotherapy and radiation therapy protectants. J Clin Oncol 27:127-145
-
(2009)
J Clin Oncol
, vol.27
, pp. 127-145
-
-
Hensley, M.L.1
Hagerty, K.L.2
Kewalramani, T.3
-
138
-
-
77957355941
-
Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: Long-term follow-up of a prospective, randomised, multicentre trial
-
Lipshultz SE, Scully RE, Lipsitz SR et al (2010) Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial. Lancet Oncol 11:950-961
-
(2010)
Lancet Oncol
, vol.11
, pp. 950-961
-
-
Lipshultz, S.E.1
Scully, R.E.2
Lipsitz, S.R.3
-
139
-
-
34447573788
-
Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats
-
DOI 10.1038/sj.bjp.0707294, PII 0707294
-
Lebrecht D, Geist A, Ketelsen UP et al (2007) Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats. Br J Pharmacol 151:771-778 (Pubitemid 47075325)
-
(2007)
British Journal of Pharmacology
, vol.151
, Issue.6
, pp. 771-778
-
-
Lebrecht, D.1
Geist, A.2
Ketelsen, U.-P.3
Haberstroh, J.4
Setzer, B.5
Walker, U.A.6
-
140
-
-
33845402341
-
Prevention of high-dose chemotherapy-induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibition
-
DOI 10.1161/CIRCULATIONAHA.106.635144, PII 0000301720061205000010
-
Cardinale D, Colombo A, Sandri MT et al (2006) Prevention of high-dose chemotherapy-induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibition. Circulation 114:2474-2481 (Pubitemid 44901520)
-
(2006)
Circulation
, vol.114
, Issue.23
, pp. 2474-2481
-
-
Cardinale, D.1
Colombo, A.2
Sandri, M.T.3
Lamantia, G.4
Colombo, N.5
Civelli, M.6
Martinelli, G.7
Veglia, F.8
Fiorentini, C.9
Cipolla, C.M.10
-
141
-
-
33845206791
-
Protective Effects of Carvedilol Against Anthracycline-Induced Cardiomyopathy
-
DOI 10.1016/j.jacc.2006.07.052, PII S0735109706022005
-
Kalay N, Basar E, Ozdogru I et al (2006) Protective effects of carvedilol against anthracycline-induced cardiomyopathy. J Am Coll Cardiol 48:2258-2262 (Pubitemid 44855419)
-
(2006)
Journal of the American College of Cardiology
, vol.48
, Issue.11
, pp. 2258-2262
-
-
Kalay, N.1
Basar, E.2
Ozdogru, I.3
Er, O.4
Cetinkaya, Y.5
Dogan, A.6
Inanc, T.7
Oguzhan, A.8
Eryol, N.K.9
Topsakal, R.10
Ergin, A.11
-
142
-
-
77955906955
-
Mechanisms of anthracycline cardiac injury: Can we identify strategies for cardioprotection?
-
Sawyer DB, Peng X, Chen B et al (2010) Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection? Prog Cardiovasc Dis 53:105-113
-
(2010)
Prog Cardiovasc Dis
, vol.53
, pp. 105-113
-
-
Sawyer, D.B.1
Peng, X.2
Chen, B.3
-
143
-
-
65449119946
-
N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes
-
Shi R, Huang CC, Aronstam RS et al (2009) N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes. BMC Pharmacol 9:7
-
(2009)
BMC Pharmacol
, vol.9
, pp. 7
-
-
Shi, R.1
Huang, C.C.2
Aronstam, R.S.3
-
145
-
-
63149139041
-
Beneficial effect of taurine treatment against doxorubicin-induced cardiotoxicity in mice
-
Ito T, Muraoka S, Takahashi K et al (2009) Beneficial effect of taurine treatment against doxorubicin-induced cardiotoxicity in mice. Adv Exp Med Biol 643:65-74
-
(2009)
Adv Exp Med Biol
, vol.643
, pp. 65-74
-
-
Ito, T.1
Muraoka, S.2
Takahashi, K.3
-
146
-
-
27144450968
-
Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction
-
DOI 10.1385/CT:5:3:257
-
Berthiaume JM, Oliveira PJ, Fariss MW, Wallace KB (2005) Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction. Cardiovasc Toxicol 5:257-267 (Pubitemid 41506867)
-
(2005)
Cardiovascular Toxicology
, vol.5
, Issue.3
, pp. 257-267
-
-
Berthiaume, J.M.1
Oliveira, P.J.2
Fariss, M.W.3
Wallace, K.B.4
-
147
-
-
34248591511
-
Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury
-
Daosukho C, Chen Y, Noel T et al (2007) Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury. Free Radic Biol Med 42:1818-1825
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 1818-1825
-
-
Daosukho, C.1
Chen, Y.2
Noel, T.3
-
148
-
-
34247593860
-
Zinc inhibits doxorubicin-activated calcineurin signal transduction pathway in H9c2 embryonic rat cardiac cells
-
Merten KE, Jiang Y, Kang YJ (2007) Zinc inhibits doxorubicin-activated calcineurin signal transduction pathway in H9c2 embryonic rat cardiac cells. Exp Biol Med (Maywood) 232:682-689 (Pubitemid 46683394)
-
(2007)
Experimental Biology and Medicine
, vol.232
, Issue.5
, pp. 682-689
-
-
Merten, K.E.1
Jiang, Y.2
Kang, Y.J.3
-
150
-
-
78751554136
-
Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation
-
Konishi M, Haraguchi G, Ohigashi H et al (2011) Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation. Cardiovasc Res 89:309-319
-
(2011)
Cardiovasc Res
, vol.89
, pp. 309-319
-
-
Konishi, M.1
Haraguchi, G.2
Ohigashi, H.3
-
151
-
-
78651429337
-
L-carnitine reduces doxorubicin-induced apoptosis through a prostacyclin-mediated pathway in neonatal rat cardiomyocytes
-
Chao HH, Liu JC, Hong HJ et al (2011) L-carnitine reduces doxorubicin-induced apoptosis through a prostacyclin-mediated pathway in neonatal rat cardiomyocytes. Int J Cardiol 146:145-152
-
(2011)
Int J Cardiol
, vol.146
, pp. 145-152
-
-
Chao, H.H.1
Liu, J.C.2
Hong, H.J.3
-
152
-
-
69949120824
-
Critical role of nuclear calcium/calmodulin-dependent protein kinase IIdeltaB in cardiomyocyte survival in cardiomyopathy
-
Little GH, Saw A, Bai Y et al (2009) Critical role of nuclear calcium/calmodulin-dependent protein kinase IIdeltaB in cardiomyocyte survival in cardiomyopathy. J Biol Chem 284:24857-24868
-
(2009)
J Biol Chem
, vol.284
, pp. 24857-24868
-
-
Little, G.H.1
Saw, A.2
Bai, Y.3
-
153
-
-
77956233231
-
Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect
-
Koka S, Das A, Zhu SG et al (2010) Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect. J Pharmacol Exp Ther 334:1023-1030
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 1023-1030
-
-
Koka, S.1
Das, A.2
Zhu, S.G.3
|