메뉴 건너뛰기




Volumn 5, Issue 3, 2005, Pages 257-267

Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction

Author keywords

tocopherol; Adriamycin; Cardiotoxicity; Doxorubicin; Mitochondria; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; DOXORUBICIN;

EID: 27144450968     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1385/CT:5:3:257     Document Type: Article
Times cited : (85)

References (43)
  • 1
    • 0026016463 scopus 로고
    • Ultrastructural alterations of the myocardium induced by doxorubicin. A scanning electron microscopic study
    • Iwasaki, T. and Suzuki, T. (1991). Ultrastructural alterations of the myocardium induced by doxorubicin. A scanning electron microscopic study. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 60(1):35-39.
    • (1991) Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. , vol.60 , Issue.1 , pp. 35-39
    • Iwasaki, T.1    Suzuki, T.2
  • 2
    • 0018189958 scopus 로고
    • Overview of cardiac pathology in relation to anthracycline cardiotoxicity
    • Ferrans, V.J. (1978). Overview of cardiac pathology in relation to anthracycline cardiotoxicity. Cancer Treat. Rep. 62(6):955-961.
    • (1978) Cancer Treat. Rep. , vol.62 , Issue.6 , pp. 955-961
    • Ferrans, V.J.1
  • 3
    • 0023630851 scopus 로고
    • The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps. A correlative study of cardiac muscle with isolated membrane fractions
    • Boucek, R.J. Jr., Olson, R. D., Brenner, D. E., Ogunbunmi, E. M., Inui, M., and Fleischer, S. (1987). The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps. A correlative study of cardiac muscle with isolated membrane fractions. J. Biol. Chem. 262(33):15,851-15,856.
    • (1987) J. Biol. Chem. , vol.262 , Issue.33
    • Boucek Jr., R.J.1    Olson, R.D.2    Brenner, D.E.3    Ogunbunmi, E.M.4    Inui, M.5    Fleischer, S.6
  • 4
    • 0018757883 scopus 로고
    • Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography
    • Alexander, J., Dainiak, N., Berger, H.J., Goldman, L., Johnstone, D., Reduto, L., et al. (1979). Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography. N. Engl. J. Med. 300(6):278-283.
    • (1979) N. Engl. J. Med. , vol.300 , Issue.6 , pp. 278-283
    • Alexander, J.1    Dainiak, N.2    Berger, H.J.3    Goldman, L.4    Johnstone, D.5    Reduto, L.6
  • 5
    • 0043237846 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiac mitochondrionopathy
    • Wallace, K.B. (2003). Doxorubicin-induced cardiac mitochondrionopathy. Pharmacol. Toxicol. 93(3):105-115.
    • (2003) Pharmacol. Toxicol. , vol.93 , Issue.3 , pp. 105-115
    • Wallace, K.B.1
  • 6
    • 0025677733 scopus 로고
    • Development of mechanisms of protection against oxidative stress in doxorubicin-resistant rat tumoral cells in culture
    • Benchekroun, M.N., Catroux, P., Montaudon, D., and Robert, J. (1990). Development of mechanisms of protection against oxidative stress in doxorubicin-resistant rat tumoral cells in culture. Free Radic. Res. Commun. 11(1-3):137-144.
    • (1990) Free Radic. Res. Commun. , vol.11 , Issue.1-3 , pp. 137-144
    • Benchekroun, M.N.1    Catroux, P.2    Montaudon, D.3    Robert, J.4
  • 7
    • 0027395931 scopus 로고
    • Oxidative stress in mouse heart by antitumoral drugs: A comparative study of doxorubicin and mitoxantrone
    • Lores Arnaiz, S. and Llesuy, S. (1993). Oxidative stress in mouse heart by antitumoral drugs: a comparative study of doxorubicin and mitoxantrone. Toxicology 77(1-2):31-38.
    • (1993) Toxicology , vol.77 , Issue.1-2 , pp. 31-38
    • Lores Arnaiz, S.1    Llesuy, S.2
  • 8
    • 33750688601 scopus 로고    scopus 로고
    • Visualization of doxorubicin-induced oxidative stress in isolated cardiac myocytes
    • Sarvazyan, N. (1996). Visualization of doxorubicin-induced oxidative stress in isolated cardiac myocytes. Am. J. Physiol. 271(5 Pt 2):H2079-H2085.
    • (1996) Am. J. Physiol. , vol.271 , Issue.5 PART 2
    • Sarvazyan, N.1
  • 9
    • 0023936660 scopus 로고
    • Evaluation of tissue indicators of oxidative stress in rats treated chronically with adriamycin
    • Thayer, W.S. (1988). Evaluation of tissue indicators of oxidative stress in rats treated chronically with adriamycin. Biochem. Pharmacol. 37(11):2189-2194.
    • (1988) Biochem. Pharmacol. , vol.37 , Issue.11 , pp. 2189-2194
    • Thayer, W.S.1
  • 10
    • 0019817511 scopus 로고
    • Mechanism of adriamycin cardiotoxicity: Evidence for oxidative stress
    • Olson, R.D., Boerth, R.C., Gerber, J.G., and Nies, A.S. (1981). Mechanism of adriamycin cardiotoxicity: evidence for oxidative stress. Life Sci. 29(14):1393-1401.
    • (1981) Life Sci. , vol.29 , Issue.14 , pp. 1393-1401
    • Olson, R.D.1    Boerth, R.C.2    Gerber, J.G.3    Nies, A.S.4
  • 11
    • 0022967083 scopus 로고
    • Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase
    • Davies, K.J. and Doroshow, J.H. (1986). Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase. J. Biol. Chem. 261(7):3060-3067.
    • (1986) J. Biol. Chem. , vol.261 , Issue.7 , pp. 3060-3067
    • Davies, K.J.1    Doroshow, J.H.2
  • 12
    • 0023028913 scopus 로고
    • Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical
    • Doroshow, J.H. and Davies, K.J. (1986). Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical. J. Biol. Chem. 261(7):3068-3074.
    • (1986) J. Biol. Chem. , vol.261 , Issue.7 , pp. 3068-3074
    • Doroshow, J.H.1    Davies, K.J.2
  • 13
    • 0021994158 scopus 로고
    • Enhancement of reactive oxygen-dependent mitochondrial membrane lipid peroxidation by the anticancer drug adriamycin
    • Mimnaugh, E.G., Trush, M.A., Bhatnagar, M., and Gram, T.E. (1985). Enhancement of reactive oxygen-dependent mitochondrial membrane lipid peroxidation by the anticancer drug adriamycin. Biochem. Pharmacol. 34(6):847-856.
    • (1985) Biochem. Pharmacol. , vol.34 , Issue.6 , pp. 847-856
    • Mimnaugh, E.G.1    Trush, M.A.2    Bhatnagar, M.3    Gram, T.E.4
  • 14
    • 0019518493 scopus 로고
    • Stimulation by adriamycin of rat heart and liver microsomal NADPH-dependent lipid peroxidation
    • Mimnaugh, E.G., Trush, M.A., and Gram, T.E. (1981). Stimulation by adriamycin of rat heart and liver microsomal NADPH-dependent lipid peroxidation. Biochem. Pharmacol. 30(20):2797-2804.
    • (1981) Biochem. Pharmacol. , vol.30 , Issue.20 , pp. 2797-2804
    • Mimnaugh, E.G.1    Trush, M.A.2    Gram, T.E.3
  • 15
    • 0017656527 scopus 로고
    • Adriamycin: The role of lipid peroxidation in cardiac toxicity and tumor response
    • Myers, C.E., McGuire, W.P., Liss, R.H., Ifrim, I., Grotzinger, K., and Young, R.C. (1977). Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response. Science 197(4299):165-167.
    • (1977) Science , vol.197 , Issue.4299 , pp. 165-167
    • Myers, C.E.1    McGuire, W.P.2    Liss, R.H.3    Ifrim, I.4    Grotzinger, K.5    Young, R.C.6
  • 16
    • 0030991136 scopus 로고    scopus 로고
    • Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin
    • Taatjes, D.J., Gaudiano, G., Resing, K., and Koch, T.H. (1997). Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin. J. Med. Chem. 40(8):1276-1286.
    • (1997) J. Med. Chem. , vol.40 , Issue.8 , pp. 1276-1286
    • Taatjes, D.J.1    Gaudiano, G.2    Resing, K.3    Koch, T.H.4
  • 17
    • 0027751822 scopus 로고
    • Dependence of nucleic acid degradation on in situ free-radical production by adriamycin
    • Feinstein, E., Canaani, E., and Weiner, L.M. (1993). Dependence of nucleic acid degradation on in situ free-radical production by adriamycin. Biochemistry 32(48):13,156-13,161.
    • (1993) Biochemistry , vol.32 , Issue.48
    • Feinstein, E.1    Canaani, E.2    Weiner, L.M.3
  • 18
    • 0021263022 scopus 로고
    • Enzymatic activation and binding of adriamycin to nuclear DNA
    • Sinha, B.K., Trush, M.A., Kennedy, K.A., and Mimnaugh, E.G. (1984). Enzymatic activation and binding of adriamycin to nuclear DNA. Cancer Res. 44(7):2892-2896.
    • (1984) Cancer Res. , vol.44 , Issue.7 , pp. 2892-2896
    • Sinha, B.K.1    Trush, M.A.2    Kennedy, K.A.3    Mimnaugh, E.G.4
  • 19
    • 0032961434 scopus 로고    scopus 로고
    • Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration
    • Serrano, J., Palmeira, C.M., Kuehl, D.W., and Wallace, K.B. (1999). Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration. Biochim. Biophys. Acta 1411(1):201-205.
    • (1999) Biochim. Biophys. Acta , vol.1411 , Issue.1 , pp. 201-205
    • Serrano, J.1    Palmeira, C.M.2    Kuehl, D.W.3    Wallace, K.B.4
  • 20
    • 0030880285 scopus 로고    scopus 로고
    • Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin
    • Palmeira, C.M., Serrano, J., Kuehl, D.W., and Wallace, K.B. (1997). Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin. Biochim. Biophys. Acta 1321(2):101-106.
    • (1997) Biochim. Biophys. Acta , vol.1321 , Issue.2 , pp. 101-106
    • Palmeira, C.M.1    Serrano, J.2    Kuehl, D.W.3    Wallace, K.B.4
  • 21
    • 1642542353 scopus 로고    scopus 로고
    • Proteomic signatures for daunomycin and adriamycin in Bacillus subtilis
    • Sender, U., Bandow, J., Engelmann, S., Lindequist, U., and Hecker, M. (2004). Proteomic signatures for daunomycin and adriamycin in Bacillus subtilis. Pharmazie 59(1):65-70.
    • (2004) Pharmazie , vol.59 , Issue.1 , pp. 65-70
    • Sender, U.1    Bandow, J.2    Engelmann, S.3    Lindequist, U.4    Hecker, M.5
  • 23
    • 0346788893 scopus 로고    scopus 로고
    • Using mitochondria-targeted molecules to study mitochondrial radical production and its consequences
    • Smith, R.A., Kelso, G.F., Blaikie, F.H., Porteous, C.M., Ledgerwood, E.C., Hughes, G., et al. (2003). Using mitochondria-targeted molecules to study mitochondrial radical production and its consequences. Biochem. Soc. Trans. 31(Pt 6):1295-1299.
    • (2003) Biochem. Soc. Trans. , vol.31 , Issue.6 PART , pp. 1295-1299
    • Smith, R.A.1    Kelso, G.F.2    Blaikie, F.H.3    Porteous, C.M.4    Ledgerwood, E.C.5    Hughes, G.6
  • 24
    • 4444315545 scopus 로고    scopus 로고
    • Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis
    • Dhanasekaran, A., Kotamraju, S., Kalivendi, S.V., Matsunaga, T., Shang, T., Keszler, A., et al. (2004). Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis. J. Biol. Chem. 279(36):37,575-37,587.
    • (2004) J. Biol. Chem. , vol.279 , Issue.36
    • Dhanasekaran, A.1    Kotamraju, S.2    Kalivendi, S.V.3    Matsunaga, T.4    Shang, T.5    Keszler, A.6
  • 25
    • 4544370680 scopus 로고    scopus 로고
    • Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury
    • Zhao, K., Zhao, G. M., Wu, D., Soong, Y., Birk, A.V., Schiller, P.W., and Szeto H.H. (2004). Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. J. Biol. Chem. 279(33):34,682-34,690.
    • (2004) J. Biol. Chem. , vol.279 , Issue.33
    • Zhao, K.1    Zhao, G.M.2    Wu, D.3    Soong, Y.4    Birk, A.V.5    Schiller, P.W.6    Szeto, H.H.7
  • 27
    • 0025091897 scopus 로고
    • Improved methods to isolate and subfractionate rat liver mitochondria. Lipid composition of the inner and outer membrane
    • Hovius, R., Lambrechts, H., Nicolay, K., and de Kruijff, B. (1990). Improved methods to isolate and subfractionate rat liver mitochondria. Lipid composition of the inner and outer membrane. Biochim. Biophys. Acta 1021(2):217-226.
    • (1990) Biochim. Biophys. Acta , vol.1021 , Issue.2 , pp. 217-226
    • Hovius, R.1    Lambrechts, H.2    Nicolay, K.3    De Kruijff, B.4
  • 28
    • 77957003282 scopus 로고
    • Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios
    • (Estabrook RaP, M.E., ed.), Academic, New York
    • Estabrook, R. (1967). Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios. In: Methods in Enzymology, Vol. 10 (Estabrook RaP, M.E., ed.), Academic, New York: pp. 41-47.
    • (1967) Methods in Enzymology , vol.10 , pp. 41-47
    • Estabrook, R.1
  • 29
    • 0018405675 scopus 로고
    • Measurement of cation transport with metallochromic indicators
    • (Fleischer IaP, L., ed.), Academic, New York
    • Scarpa, A. (1979). Measurement of cation transport with metallochromic indicators. In: Methods in Enzymology, Vol. 56 (Fleischer IaP, L., ed.), Academic, New York: pp. 301-352.
    • (1979) Methods in Enzymology , vol.56 , pp. 301-352
    • Scarpa, A.1
  • 30
    • 0029941234 scopus 로고    scopus 로고
    • Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicin
    • Solem, L.E., Heller, L.J., and Wallace, K.B. (1996). Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicin. J. Mol. Cell Cardiol. 28(5):1023-1032
    • (1996) J. Mol. Cell Cardiol. , vol.28 , Issue.5 , pp. 1023-1032
    • Solem, L.E.1    Heller, L.J.2    Wallace, K.B.3
  • 31
    • 0028291974 scopus 로고
    • Carbonyl assays for determination of oxidatively modified proteins
    • Levine, R.L., Williams, J.A., Stadtman, E.R., and Shacter, E. (1994). Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol. 233:346-357.
    • (1994) Methods Enzymol. , vol.233 , pp. 346-357
    • Levine, R.L.1    Williams, J.A.2    Stadtman, E.R.3    Shacter, E.4
  • 32
    • 0032503053 scopus 로고    scopus 로고
    • Sensitive method for measuring tissue alpha-tocopherol and alpha-tocopheryloxybutyric acid by high-performance liquid chromatography with fluorometric detection
    • Tirmenstein, M.A., Watson, B.W., Haar, N.C., and Fariss, M.W. (1998). Sensitive method for measuring tissue alpha-tocopherol and alpha- tocopheryloxybutyric acid by high-performance liquid chromatography with fluorometric detection. J. Chromatogr. B. Biomed. Sci. Appl. 707(1-2):308-311.
    • (1998) J. Chromatogr. B. Biomed. Sci. Appl. , vol.707 , Issue.1-2 , pp. 308-311
    • Tirmenstein, M.A.1    Watson, B.W.2    Haar, N.C.3    Fariss, M.W.4
  • 33
  • 34
    • 0019413926 scopus 로고
    • Anthracycline-associated cardiac and renal damage in rabbits. Evidence for mediation by vasoactive substances
    • Bristow, M.R., Minobe, W.A., Billingham, M.E., Marmor, J.B., Johnson, G.A., Ishimoto, B.M., et al. (1981). Anthracycline-associated cardiac and renal damage in rabbits. Evidence for mediation by vasoactive substances. Lab. Invest. 45(2):157-168.
    • (1981) Lab. Invest. , vol.45 , Issue.2 , pp. 157-168
    • Bristow, M.R.1    Minobe, W.A.2    Billingham, M.E.3    Marmor, J.B.4    Johnson, G.A.5    Ishimoto, B.M.6
  • 35
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 36
    • 0030855953 scopus 로고    scopus 로고
    • Adriamycin cardiomyopathy: Pathophysiology and prevention
    • Singal, P.K., Iliskovic, N., Li, T., and Kumar, D. (1997). Adriamycin cardiomyopathy: pathophysiology and prevention. FASEB J. 11(12):931-936.
    • (1997) FASEB J. , vol.11 , Issue.12 , pp. 931-936
    • Singal, P.K.1    Iliskovic, N.2    Li, T.3    Kumar, D.4
  • 37
  • 39
    • 0028130476 scopus 로고
    • Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration
    • Solem, L.E., Henry, T.R., and Wallace, K.B. (1994). Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration. Toxicol. Appl. Pharmacol. 129(2):214-222.
    • (1994) Toxicol. Appl. Pharmacol. , vol.129 , Issue.2 , pp. 214-222
    • Solem, L.E.1    Henry, T.R.2    Wallace, K.B.3
  • 40
    • 0035863469 scopus 로고    scopus 로고
    • Cumulative and irreversible cardiac mitochondrial dysfunction induced by doxorubicin
    • Zhou, S., Starkov, A., Froberg, M.K., Leino, R.L., and Wallace, K.B. (2001). Cumulative and irreversible cardiac mitochondrial dysfunction induced by doxorubicin. Cancer Res. 61(2):771-777.
    • (2001) Cancer Res. , vol.61 , Issue.2 , pp. 771-777
    • Zhou, S.1    Starkov, A.2    Froberg, M.K.3    Leino, R.L.4    Wallace, K.B.5
  • 42
    • 4644344464 scopus 로고    scopus 로고
    • Chemopreventive effect of dietary d-alpha-tocopheryl succinate supplementation on precancer colon aberrant crypt formation and vitamin E analogue levels in young and old rats
    • Exon, J.H., South, E.H., Taruscio, T.G., Clifton, G.D., and Fariss, M.W. (2004). Chemopreventive effect of dietary d-alpha-tocopheryl succinate supplementation on precancer colon aberrant crypt formation and vitamin E analogue levels in young and old rats. Nutr. Cancer 49(1):72-80.
    • (2004) Nutr. Cancer , vol.49 , Issue.1 , pp. 72-80
    • Exon, J.H.1    South, E.H.2    Taruscio, T.G.3    Clifton, G.D.4    Fariss, M.W.5
  • 43
    • 0037735348 scopus 로고    scopus 로고
    • Vitamin E therapy in Parkinson's disease
    • Fariss, M.W. and Zhang, J.G. (2003). Vitamin E therapy in Parkinson's disease. Toxicology 189(1-2):129-146.
    • (2003) Toxicology , vol.189 , Issue.1-2 , pp. 129-146
    • Fariss, M.W.1    Zhang, J.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.