Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes

Journal of Biological Chemistry

Volumn 282, Issue 2, 2007, Pages 1152-1160

  Ito, Takashi ^a   Fujio, Yasushi ^a   Takahashi, Kyoko ^a   Azuma, Junichi ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC MYOCYTES; HYPEROSMOTIC STRESS; IMMUNOPRECIPITATION; TRANSCRIPTIONAL REGULATORS;

BIOASSAY; BIOLOGICAL ORGANS; CELLS; CYTOTOXICITY; DEGRADATION; IMMUNOLOGY; RNA;

TRANSCRIPTION FACTORS;

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CREATINE KINASE; DOXORUBICIN; INOSITOL; MESSENGER RNA; PROTEASOME INHIBITOR; SMALL INTERFERING RNA; TAURINE TRANSPORTER; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT5; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; NFAT5 PROTEIN, RAT; PROTEASOME; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARDIOTOXICITY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DOWN REGULATION; GENE INDUCTION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; HEART PROTECTION; IMMUNOPRECIPITATION; MUSCLE CELL; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; TRANSCRIPTION REGULATION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENETICS; METABOLISM; OSMOTIC PRESSURE; PHYSIOLOGY; WISTAR KYOTO RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; DOXORUBICIN; MYOCYTES, CARDIAC; OSMOTIC PRESSURE; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, INBRED WKY; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 33847753121     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M609547200     Document Type: Article

References (58)

1. Minotti, G., Menna, P., Salvatorelli, E., Cairo, G., and Gianni, L. (2004) Pharmacol. Rev. 56, 185-229
2. Singal, P. K., and Iliskovic, N. (1998) N. Engl. J. Med. 339, 900-905
3. Arai, M., Tomaru, K., Takizawa, T., Sekiguchi, K., Yokoyama, T., Suzuki, T., and Nagai, R. (1998) J. Mol. Cell. Cardiol. 30, 243-254
4. Ito, H., Miller, S. C., Billingham, M. E., Akimoto, H., Torti, S. V., Wade, R., Gahlmann, R., Lyons, G., Kedes, L., and Torti, F. M. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 4275-4279
5. Poizat, C., Sartorelli, V., Chung, G., Kloner, R. A., and Kedes, L. (2000) Mol. Cell. Biol. 20, 8643-8654
6. Kumarapeli, A. R., Horak, K. M., Glasford, J. W., Li, J., Chen, Q., Liu, J., Zheng, H., and Wang, X. (2005) FASEB J. 19, 2051-2053
7. Ho, S. N. (2003) Arch. Biochem. Biophys. 413, 151-157
8. Woo, S. K., Lee, S. D., and Kwon, H. M. (2002) Pflugers Arch. Eur. J. Physiol. Pfluegers Arch. Gesamte Physiol. Menschen Tiere 444, 579-585
9. Ko, B. C., Turck, C. W., Lee, K. W., Yang, Y., and Chung, S. S. (2000) Biochem. Biophys. Res. Commun. 270, 52-61
10. Ito, T., Fujio, Y., Hirata, M., Takatani, T., Matsuda, T., Muraoka, S., Takahashi, K., and Azuma, J. (2004) Biochem. J. 382, 177-182
11. Miyakawa, H., Woo, S. K., Dahl, S. C., Handler, J. S., and Kwon, H. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2538-2542
12. Bosman, D. K., Deutz, N. E., Maas, M. A., van Eijk, H. M., Smit, J. J., de Haan, J. G., and Chamuleau, R. A. (1992) J. Neurochem. 59, 591-599
13. Rim, J. S., Atta, M. G., Dahl, S. C., Berry, G. T., Handler, J. S., and Kwon, H. M. (1998) J. Biol. Chem. 273, 20615-20621
14. Woo, S. K., Lee, S. D., Na, K. Y., Park, W. K., and Kwon, H. M. (2002) Mol. Cell. Biol. 22, 5753-5760
15. Kojima, R., Randall, J. D., Ito, E., Manshio, H., Suzuki, Y., and Gullans, S. R. (2004) Biochem. J. 380, 783-794
16. Trama, J., Go, W. Y., and Ho, S. N. (2002) J. Immunol. 169, 5477-5488
17. Trama, J., Lu, Q., Hawley, R. G., and Ho, S. N. (2000) J. Immunol. 165, 4884-4894
18. Maouyo, D., Kim, J. Y., Lee, S. D., Wu, Y., Woo, S. K., and Kwon, H. M. (2002) Am. J. Physiol. 282, F802-F809
19. Lopez-Rodriguez, C., Antos, C. L., Shelton, J. M., Richardson, J. A., Lin, F., Novobrantseva, T. I., Bronson, R. T., Igarashi, P., Rao, A., and Olson, E. N. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 2392-2397
20. Wang, Y., Ko, B. C., Yang, J. Y., Lam, T. T., Jiang, Z., Zhang, J., Chung, S. K., and Chung, S. S. (2005) J. Biol. Chem. 280, 19986-19991
21. Fujio, Y., Matsuda, T., Oshima, Y., Maeda, M., Mohri, T., Ito, T., Takatani, T., Hirata, M., Nakaoka, Y., Kimura, R., Kishimoto, T., and Azuma, J. (2004) FEBS Lett. 573, 202-206
22. Sadoshima, J., Jahn, L., Takahashi, T., Kulik, T. J., and Izumo, S. (1992) J. Biol. Chem. 267, 10551-10560
23. Matsuda, T., Fujio, Y., Nariai, T., Ito, T., Yamane, M., Takatani, T., Takahashi, K., and Azuma, J. (2006) J. Mol. Cell. Cardiol. 40, 495-502
24. Uozumi, Y., Ito, T., Hoshino, Y., Mohri, T., Maeda, M., Takahashi, K., Fujio, Y., and Azuma, J. (2006) Biochem. J. 394, 699-706
25. Lopez-Rodriguez, C., Aramburu, J., Rakeman, A. S., and Rao, A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7214-7219
26. Gomez-Foix, A. M., Coats, W. S., Baque, S., Alam, T., Gerard, R. D., and Newgard, C. B. (1992) J. Biol. Chem. 267, 25129-25134
27. Takahashi, K., Ohyabu, Y., Solodushko, V., Takatani, T., Itoh, T., Schaffer, S. W., and Azuma, J. (2003) J. Cardiovasc. Pharmacol. 41, 726-733
28. Zhang, Z., Ferraris, J. D., Brooks, H. L., Brisc, I., and Burg, M. B. (2003) Am. J. Physiol. 285, F688-F693
29. Poizat, C., Puri, P. L., Bai, Y., and Kedes, L. (2005) Mol. Cell. Biol. 25, 2673-2687
30. Lou, H., Danelisen, I., and Singal, P. K. (2005) Am. J. Physiol. 288, H1925-H1930
31. Spallarossa, P., Altieri, P., Garibaldi, S., Ghigliotti, G., Barisione, C., Manca, V., Fabbi, P., Ballestrero, A., Brunelli, C., and Barsotti, A. (2006) Cardiovasc. Res. 69, 736-745
32. Irarrazabal, C. E., Liu, J. C., Burg, M. B., and Ferraris, J. D. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 8809-8814
33. Ko, B. C., Lam, A. K., Kapus, A., Fan, L., Chung, S. K., and Chung, S. S. (2002) J. Biol. Chem. 277, 46085-46092
34. Ferraris, J. D., Persaud, P., Williams, C. K., Chen, Y., and Burg, M. B. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 16800-16805
35. Hochstrasser, M. (1996) Annu. Rev. Genet. 30, 405-439
36. Murakami, Y., Matsufuji, S., Kameji, T., Hayashi, S., Igarashi, K., Tamura, T., Tanaka, K., and Ichihara, A. (1992) Nature 360, 597-599
37. Li, X., Lonard, D. M., Jung, S. Y., Malovannaya, A., Feng, Q., Qin, J., Tsai, S. Y., Tsai, M. J., and O'Malley, B. W. (2006) Cell 124, 381-392
38. Sheaff, R. J., Singer, J. D., Swanger, J., Smitherman, M., Roberts, J. M., and Clurman, B. E. (2000) Mol. Cell 5, 403-410
39. Asher, G., Bercovich, Z., Tsvetkov, P., Shaul, Y., and Kahana, C. (2005) Mol. Cell 17, 645-655
40. Anwar, A., Dehn, D., Siegel, D., Kepa, J. K., Tang, L. J., Pietenpol, J. A., and Ross, D. (2003) J. Biol. Chem. 278, 10368-10373
41. Dahl, S. C., Handler, J. S., and Kwon, H. M. (2001) Am. J. Physiol. 280, C248-C253
42. Lee, S. D., Woo, S. K., and Kwon, H. M. (2002) Biochem. Biophys. Res. Commun. 294, 968-975
43. Aihara, Y., Kurabayashi, M., Tanaka, T., Takeda, S. I., Tomaru, K., Sekiguchi, K. I., Ohyama, Y., and Nagai, R. (2000) J. Mol. Cell. Cardiol. 32, 1401-1414
44. Kalivendi, S. V., Konorev, E. A., Cunningham, S., Vanamala, S. K., Kaji, E. H., Joseph, J., and Kalyanaraman, B. (2005) Biochem. J. 389, 527-539
45. Wang, S., Kotamraju, S., Konorev, E., Kalivendi, S., Joseph, J., and Kalyanaraman, B. (2002) Biochem. J. 367, 729-740
46. Chesney, R. W. (1985) Adv. Pediatr. 32, 1-42
47. Huxtable, R. J. (1992) Physiol. Rev. 72, 101-163
48. Hamaguchi, T., Azuma, J., Harada, H., Takahashi, K., Kishimoto, S., and Schaffer, S. W. (1989) Pharmacol. Res. 21, 729-734
49. Hamaguchi, T., Azuma, J., Awata, N., Ohta, H., Takihara, K., Harada, H., Kishimoto, S., and Sperelakis, N. (1988) Res. Commun. Chem. Pathol. Pharmacol. 59, 21-30
50. Takatani, T., Takahashi, K., Uozumi, Y., Matsuda, T., Ito, T., Schaffer, S. W., Fujio, Y., and Azuma, J. (2004) Biochem. Biophys. Res. Commun. 316, 484-489
51. Azuma, J., Hasegawa, H., Sawamura, A., Awata, N., Harada, H., Ogura, K., and Kishimoto, S. (1982) Int. J. Cardiol. 2, 303-304
52. Takihara, K., Azuma, J., Awata, N., Ohta, H., Hamaguchi, T., Sawamura, A., Tanaka, Y., Kishimoto, S., and Sperelakis, N. (1986) Am. Heart J. 112, 1278-1284
53. Kitamura, H., Yamauchi, A., Sugiura, T., Matsuoka, Y., Horio, M., Tohyama, M., Shimada, S., Imai, E., and Hori, M. (1998) Kidney Int. 53, 146-153
54. Craig, S. A. (2004) Am. J. Clin. Nutr. 80, 539-549
55. Latchman, D. S. (2001) Cardiovasc. Res. 51, 637-646
56. Soti, C., Nagy, E., Giricz, Z., Vigh, L., Csermely, P., and Ferdinandy, P. (2005) Br. J. Pharmacol. 146, 769-780
57. Ito, H., Shimojo, T., Fujisaki, H., Tamamori, M., Ishiyama, S., Adachi, S., Abe, S., Marumo, F., and Hiroe, M. (1999) Life Sci. 64, 755-761
58. Kukan, M. (2004) J. Physiol. Pharmacol. 55, 3-15