Adiponectin activation of AMPK disrupts leptin-mediated hepatic fibrosis via Suppressors of Cytokine Signaling (SOCS-3)

Journal of Cellular Biochemistry

Volumn 110, Issue 5, 2010, Pages 1195-1207

  Handy, Jeffrey A ^a,b   Saxena, Neeraj K ^a   Fu, Pingping ^a   Lin, Songbai ^a   Mells, Jamie E ^a,c   Gupta, Nitika A ^a   Anania, Frank A ^a,c  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

Adipocytokines; AMPK; Fibrosis; Jak Stat; Stellate cells

Indexed keywords

ADENOSINE PHOSPHATE; ADIPONECTIN; CARBON TETRACHLORIDE; COLLAGEN; INTERSTITIAL COLLAGENASE; JANUS KINASE; LEPTIN; MESSENGER RNA; RECOMBINANT ADIPONECTIN; RECOMBINANT LEPTIN; RECOMBINANT PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL LYSATE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FLUOROMETRY; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INFLAMMATION; KNOCKOUT MOUSE; LIVER FIBROSIS; LIVER INJURY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STELLATE CELL; WILD TYPE;

ADIPONECTIN; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BLOTTING, WESTERN; CARBON TETRACHLORIDE; CELLS, CULTURED; FEMALE; HEPATIC STELLATE CELLS; HUMANS; LEPTIN; LIVER CIRRHOSIS; MALE; MATRIX METALLOPROTEINASE 1; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFECTION;

MUS;

EID: 77954908071     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22634     Document Type: Article

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