-
1
-
-
69149083668
-
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
-
Stamatatos L, Morris L, Burton DR, Mascola JR, (2009) Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine? Nat Med 15: 866-870.
-
(2009)
Nat Med
, vol.15
, pp. 866-870
-
-
Stamatatos, L.1
Morris, L.2
Burton, D.R.3
Mascola, J.R.4
-
2
-
-
53349160053
-
Challenges in the development of an HIV-1 vaccine
-
Barouch DH, (2008) Challenges in the development of an HIV-1 vaccine. Nature 455: 613-619.
-
(2008)
Nature
, vol.455
, pp. 613-619
-
-
Barouch, D.H.1
-
3
-
-
38349081511
-
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus
-
Karlsson Hedestam GB, Fouchier RA, Phogat S, Burton DR, Sodroski J, et al. (2008) The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus. Nat Rev Microbiol 6: 143-155.
-
(2008)
Nat Rev Microbiol
, vol.6
, pp. 143-155
-
-
Karlsson Hedestam, G.B.1
Fouchier, R.A.2
Phogat, S.3
Burton, D.R.4
Sodroski, J.5
-
4
-
-
38949204965
-
HIV-1 neutralization: mechanisms and relevance to vaccine design
-
Zwick MB, Burton DR, (2007) HIV-1 neutralization: mechanisms and relevance to vaccine design. Curr HIV Res 5: 608-624.
-
(2007)
Curr HIV Res
, vol.5
, pp. 608-624
-
-
Zwick, M.B.1
Burton, D.R.2
-
5
-
-
0030897825
-
Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex
-
Fouts TR, Binley JM, Trkola A, Robinson JE, Moore JP, (1997) Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex. J Virol 71: 2779-2785.
-
(1997)
J Virol
, vol.71
, pp. 2779-2785
-
-
Fouts, T.R.1
Binley, J.M.2
Trkola, A.3
Robinson, J.E.4
Moore, J.P.5
-
6
-
-
0035155850
-
Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers
-
Yang X, Wyatt R, Sodroski J, (2001) Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers. J Virol 75: 1165-1171.
-
(2001)
J Virol
, vol.75
, pp. 1165-1171
-
-
Yang, X.1
Wyatt, R.2
Sodroski, J.3
-
7
-
-
0028999803
-
Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer
-
Sattentau QJ, Moore JP, (1995) Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer. J Exp Med 182: 185-196.
-
(1995)
J Exp Med
, vol.182
, pp. 185-196
-
-
Sattentau, Q.J.1
Moore, J.P.2
-
8
-
-
0037213278
-
Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies
-
Poignard P, Moulard M, Golez E, Vivona V, Franti M, et al. (2003) Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies. J Virol 77: 353-365.
-
(2003)
J Virol
, vol.77
, pp. 353-365
-
-
Poignard, P.1
Moulard, M.2
Golez, E.3
Vivona, V.4
Franti, M.5
-
9
-
-
33144486096
-
Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1
-
Moore PL, Crooks ET, Porter L, Zhu P, Cayanan CS, et al. (2006) Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1. J Virol 80: 2515-2528.
-
(2006)
J Virol
, vol.80
, pp. 2515-2528
-
-
Moore, P.L.1
Crooks, E.T.2
Porter, L.3
Zhu, P.4
Cayanan, C.S.5
-
10
-
-
77949378988
-
In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type-1
-
Leaman DP, Kinkead H, Zwick MB, (2010) In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type-1. J Virol 84: 3382-3395.
-
(2010)
J Virol
, vol.84
, pp. 3382-3395
-
-
Leaman, D.P.1
Kinkead, H.2
Zwick, M.B.3
-
11
-
-
0023921610
-
Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus
-
McCune JM, Rabin LB, Feinberg MB, Lieberman M, Kosek JC, et al. (1988) Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus. Cell 53: 55-67.
-
(1988)
Cell
, vol.53
, pp. 55-67
-
-
McCune, J.M.1
Rabin, L.B.2
Feinberg, M.B.3
Lieberman, M.4
Kosek, J.C.5
-
12
-
-
0025292252
-
Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells
-
Leonard CK, Spellman MW, Riddle L, Harris RJ, Thomas JN, et al. (1990) Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. J Biol Chem 265: 10373-10382.
-
(1990)
J Biol Chem
, vol.265
, pp. 10373-10382
-
-
Leonard, C.K.1
Spellman, M.W.2
Riddle, L.3
Harris, R.J.4
Thomas, J.N.5
-
13
-
-
72849117137
-
Roles of the interactions between Env and Gag proteins in the HIV-1 replication cycle
-
Murakami T, (2008) Roles of the interactions between Env and Gag proteins in the HIV-1 replication cycle. Microbiol Immunol 52: 287-295.
-
(2008)
Microbiol Immunol
, vol.52
, pp. 287-295
-
-
Murakami, T.1
-
14
-
-
0021720872
-
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
-
Klatzmann D, Champagne E, Chamaret S, Gruest J, Guetard D, et al. (1984) T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature 312: 767-768.
-
(1984)
Nature
, vol.312
, pp. 767-768
-
-
Klatzmann, D.1
Champagne, E.2
Chamaret, S.3
Gruest, J.4
Guetard, D.5
-
15
-
-
0021751840
-
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
-
Dalgleish AG, Beverley PC, Clapham PR, Crawford DH, Greaves MF, et al. (1984) The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature 312: 763-767.
-
(1984)
Nature
, vol.312
, pp. 763-767
-
-
Dalgleish, A.G.1
Beverley, P.C.2
Clapham, P.R.3
Crawford, D.H.4
Greaves, M.F.5
-
16
-
-
32544446940
-
HIV and the chemokine system: 10 years later
-
Lusso P, (2006) HIV and the chemokine system: 10 years later. EMBO J 25: 447-456.
-
(2006)
EMBO J
, vol.25
, pp. 447-456
-
-
Lusso, P.1
-
17
-
-
0037769964
-
The HIV Env-mediated fusion reaction
-
Gallo SA, Finnegan CM, Viard M, Raviv Y, Dimitrov A, et al. (2003) The HIV Env-mediated fusion reaction. Biochim Biophys Acta 1614: 36-50.
-
(2003)
Biochim Biophys Acta
, vol.1614
, pp. 36-50
-
-
Gallo, S.A.1
Finnegan, C.M.2
Viard, M.3
Raviv, Y.4
Dimitrov, A.5
-
18
-
-
0025572710
-
Dissociation of gp120 from HIV-1 virions induced by soluble CD4
-
Moore JP, McKeating JA, Weiss RA, Sattentau QJ, (1990) Dissociation of gp120 from HIV-1 virions induced by soluble CD4. Science 250: 1139-1142.
-
(1990)
Science
, vol.250
, pp. 1139-1142
-
-
Moore, J.P.1
McKeating, J.A.2
Weiss, R.A.3
Sattentau, Q.J.4
-
19
-
-
0027399209
-
Two mechanisms of soluble CD4 (sCD4)-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) infectivity and their relation to primary HIV-1 isolates with reduced sensitivity to sCD4
-
Orloff SL, Kennedy MS, Belperron AA, Maddon PJ, McDougal JS, (1993) Two mechanisms of soluble CD4 (sCD4)-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) infectivity and their relation to primary HIV-1 isolates with reduced sensitivity to sCD4. J Virol 67: 1461-1471.
-
(1993)
J Virol
, vol.67
, pp. 1461-1471
-
-
Orloff, S.L.1
Kennedy, M.S.2
Belperron, A.A.3
Maddon, P.J.4
McDougal, J.S.5
-
20
-
-
0027173841
-
Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120
-
Fu YK, Hart TK, Jonak ZL, Bugelski PJ, (1993) Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120. J Virol 67: 3818-3825.
-
(1993)
J Virol
, vol.67
, pp. 3818-3825
-
-
Fu, Y.K.1
Hart, T.K.2
Jonak, Z.L.3
Bugelski, P.J.4
-
21
-
-
0026601827
-
Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates
-
Moore JP, McKeating JA, Huang YX, Ashkenazi A, Ho DD, (1992) Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates. J Virol 66: 235-243.
-
(1992)
J Virol
, vol.66
, pp. 235-243
-
-
Moore, J.P.1
McKeating, J.A.2
Huang, Y.X.3
Ashkenazi, A.4
Ho, D.D.5
-
22
-
-
66349110542
-
Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state
-
Haim H, Si Z, Madani N, Wang L, Courter JR, et al. (2009) Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. PLoS Pathog 5: e1000360.
-
(2009)
PLoS Pathog
, vol.5
-
-
Haim, H.1
Si, Z.2
Madani, N.3
Wang, L.4
Courter, J.R.5
-
23
-
-
0036091692
-
Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus
-
Chertova E, Bess JW Jr, Crise BJ, Sowder IR, Schaden TM, et al. (2002) Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus. J Virol 76: 5315-5325.
-
(2002)
J Virol
, vol.76
, pp. 5315-5325
-
-
Chertova, E.1
Bess Jr., J.W.2
Crise, B.J.3
Sowder, I.R.4
Schaden, T.M.5
-
24
-
-
0037223708
-
Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site
-
Herrera C, Spenlehauer C, Fung MS, Burton DR, Beddows S, et al. (2003) Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site. J Virol 77: 1084-1091.
-
(2003)
J Virol
, vol.77
, pp. 1084-1091
-
-
Herrera, C.1
Spenlehauer, C.2
Fung, M.S.3
Burton, D.R.4
Beddows, S.5
-
25
-
-
13544252604
-
Neutralizing as well as non-neutralizing polyclonal immunoglobulin (Ig)G from infected patients capture HIV-1 via antibodies directed against the principal immunodominant domain of gp41
-
Burrer R, Haessig-Einius S, Aubertin AM, Moog C, (2005) Neutralizing as well as non-neutralizing polyclonal immunoglobulin (Ig)G from infected patients capture HIV-1 via antibodies directed against the principal immunodominant domain of gp41. Virology 333: 102-113.
-
(2005)
Virology
, vol.333
, pp. 102-113
-
-
Burrer, R.1
Haessig-Einius, S.2
Aubertin, A.M.3
Moog, C.4
-
26
-
-
12344251568
-
Inter-subunit disulfide bonds in soluble HIV-1 envelope glycoprotein trimers
-
Yuan W, Craig S, Yang X, Sodroski J, (2005) Inter-subunit disulfide bonds in soluble HIV-1 envelope glycoprotein trimers. Virology 332: 369-383.
-
(2005)
Virology
, vol.332
, pp. 369-383
-
-
Yuan, W.1
Craig, S.2
Yang, X.3
Sodroski, J.4
-
27
-
-
12344264596
-
Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage
-
Pancera M, Wyatt R, (2005) Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage. Virology 332: 145-156.
-
(2005)
Virology
, vol.332
, pp. 145-156
-
-
Pancera, M.1
Wyatt, R.2
-
28
-
-
38949090023
-
N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus
-
Dey AK, David KB, Ray N, Ketas TJ, Klasse PJ, et al. (2008) N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus. Virology 372: 187-200.
-
(2008)
Virology
, vol.372
, pp. 187-200
-
-
Dey, A.K.1
David, K.B.2
Ray, N.3
Ketas, T.J.4
Klasse, P.J.5
-
29
-
-
20644433322
-
The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles
-
Herrera C, Klasse PJ, Michael E, Kake S, Barnes K, et al. (2005) The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles. Virology 338: 154-172.
-
(2005)
Virology
, vol.338
, pp. 154-172
-
-
Herrera, C.1
Klasse, P.J.2
Michael, E.3
Kake, S.4
Barnes, K.5
-
30
-
-
0027985431
-
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
-
Burton DR, Pyati J, Koduri R, Sharp SJ, Thornton GB, et al. (1994) Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 266: 1024-1027.
-
(1994)
Science
, vol.266
, pp. 1024-1027
-
-
Burton, D.R.1
Pyati, J.2
Koduri, R.3
Sharp, S.J.4
Thornton, G.B.5
-
31
-
-
9044241681
-
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
-
Trkola A, Purtscher M, Muster T, Ballaun C, Buchacher A, et al. (1996) Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1. J Virol 70: 1100-1108.
-
(1996)
J Virol
, vol.70
, pp. 1100-1108
-
-
Trkola, A.1
Purtscher, M.2
Muster, T.3
Ballaun, C.4
Buchacher, A.5
-
32
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker LM, Phogat SK, Chan-Hui PY, Wagner D, Phung P, et al. (2009) Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326: 285-289.
-
(2009)
Science
, vol.326
, pp. 285-289
-
-
Walker, L.M.1
Phogat, S.K.2
Chan-Hui, P.Y.3
Wagner, D.4
Phung, P.5
-
33
-
-
0027378573
-
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
-
Muster T, Steindl F, Purtscher M, Trkola A, Klima A, et al. (1993) A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J Virol 67: 6642-6647.
-
(1993)
J Virol
, vol.67
, pp. 6642-6647
-
-
Muster, T.1
Steindl, F.2
Purtscher, M.3
Trkola, A.4
Klima, A.5
-
34
-
-
0034759882
-
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
-
Zwick MB, Labrijn AF, Wang M, Spenlehauer C, Saphire EO, et al. (2001) Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J Virol 75: 10892-10905.
-
(2001)
J Virol
, vol.75
, pp. 10892-10905
-
-
Zwick, M.B.1
Labrijn, A.F.2
Wang, M.3
Spenlehauer, C.4
Saphire, E.O.5
-
35
-
-
77954920017
-
Rational design of envelope surface identifies broadly neutralizing human monoclonal antibodies to HIV-1
-
Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, et al. (2010) Rational design of envelope surface identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science 329: 856-861.
-
(2010)
Science
, vol.329
, pp. 856-861
-
-
Wu, X.1
Yang, Z.Y.2
Li, Y.3
Hogerkorp, C.M.4
Schief, W.R.5
-
36
-
-
33748038359
-
Cryo-Electron Tomographic Structure of an Immunodeficiency Virus Envelope Complex In Situ
-
Zanetti G, Briggs JA, Grunewald K, Sattentau QJ, Fuller SD, (2006) Cryo-Electron Tomographic Structure of an Immunodeficiency Virus Envelope Complex In Situ. PLoS Pathog 2: e83.
-
(2006)
PLoS Pathog
, vol.2
-
-
Zanetti, G.1
Briggs, J.A.2
Grunewald, K.3
Sattentau, Q.J.4
Fuller, S.D.5
-
37
-
-
57149107577
-
Cryoelectron tomography of HIV-1 envelope spikes: further evidence for tripod-like legs
-
Zhu P, Winkler H, Chertova E, Taylor KA, Roux KH, (2008) Cryoelectron tomography of HIV-1 envelope spikes: further evidence for tripod-like legs. PLoS Pathog 4: e1000203.
-
(2008)
PLoS Pathog
, vol.4
-
-
Zhu, P.1
Winkler, H.2
Chertova, E.3
Taylor, K.A.4
Roux, K.H.5
-
38
-
-
51349162563
-
Molecular architecture of native HIV-1 gp120 trimers
-
Liu J, Bartesaghi A, Borgnia MJ, Sapiro G, Subramaniam S, (2008) Molecular architecture of native HIV-1 gp120 trimers. Nature 455: 109-113.
-
(2008)
Nature
, vol.455
, pp. 109-113
-
-
Liu, J.1
Bartesaghi, A.2
Borgnia, M.J.3
Sapiro, G.4
Subramaniam, S.5
-
39
-
-
78650426126
-
Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure
-
Wu SR, Loving R, Lindqvist B, Hebert H, Koeck PJ, et al. (2010) Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure. Proc Natl Acad Sci U S A 107: 18844-18849.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 18844-18849
-
-
Wu, S.R.1
Loving, R.2
Lindqvist, B.3
Hebert, H.4
Koeck, P.J.5
-
40
-
-
65249185539
-
Structure of the HIV-1 gp41 membrane-proximal ectodomain region in a putative prefusion conformation
-
Liu J, Deng Y, Dey AK, Moore JP, Lu M, (2009) Structure of the HIV-1 gp41 membrane-proximal ectodomain region in a putative prefusion conformation. Biochemistry 48: 2915-2923.
-
(2009)
Biochemistry
, vol.48
, pp. 2915-2923
-
-
Liu, J.1
Deng, Y.2
Dey, A.K.3
Moore, J.P.4
Lu, M.5
-
41
-
-
37849000389
-
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
-
Sun ZY, Oh KJ, Kim M, Yu J, Brusic V, et al. (2008) HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane. Immunity 28: 52-63.
-
(2008)
Immunity
, vol.28
, pp. 52-63
-
-
Sun, Z.Y.1
Oh, K.J.2
Kim, M.3
Yu, J.4
Brusic, V.5
-
42
-
-
0032543555
-
The antigenic structure of the HIV gp120 envelope glycoprotein
-
Wyatt R, Kwong PD, Desjardins E, Sweet RW, Robinson J, et al. (1998) The antigenic structure of the HIV gp120 envelope glycoprotein. Nature 393: 705-711.
-
(1998)
Nature
, vol.393
, pp. 705-711
-
-
Wyatt, R.1
Kwong, P.D.2
Desjardins, E.3
Sweet, R.W.4
Robinson, J.5
-
43
-
-
0033919404
-
Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus
-
Kwong PD, Wyatt R, Sattentau QJ, Sodroski J, Hendrickson WA, (2000) Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus. J Virol 74: 1961-1972.
-
(2000)
J Virol
, vol.74
, pp. 1961-1972
-
-
Kwong, P.D.1
Wyatt, R.2
Sattentau, Q.J.3
Sodroski, J.4
Hendrickson, W.A.5
-
44
-
-
0026069632
-
Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein
-
Helseth E, Olshevsky U, Furman C, Sodroski J, (1991) Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein. J Virol 65: 2119-2123.
-
(1991)
J Virol
, vol.65
, pp. 2119-2123
-
-
Helseth, E.1
Olshevsky, U.2
Furman, C.3
Sodroski, J.4
-
45
-
-
0037213299
-
Concordant modulation of neutralization resistance and high infectivity of the primary human immunodeficiency virus type 1 MN strain and definition of a potential gp41 binding site in gp120
-
Leavitt M, Park EJ, Sidorov IA, Dimitrov DS, Quinnan GV Jr, (2003) Concordant modulation of neutralization resistance and high infectivity of the primary human immunodeficiency virus type 1 MN strain and definition of a potential gp41 binding site in gp120. J Virol 77: 560-570.
-
(2003)
J Virol
, vol.77
, pp. 560-570
-
-
Leavitt, M.1
Park, E.J.2
Sidorov, I.A.3
Dimitrov, D.S.4
Quinnan Jr., G.V.5
-
46
-
-
0033985999
-
A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure
-
Binley JM, Sanders RW, Clas B, Schuelke N, Master A, et al. (2000) A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure. J Virol 74: 627-643.
-
(2000)
J Virol
, vol.74
, pp. 627-643
-
-
Binley, J.M.1
Sanders, R.W.2
Clas, B.3
Schuelke, N.4
Master, A.5
-
47
-
-
13844302894
-
Structure of an unliganded simian immunodeficiency virus gp120 core
-
Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, et al. (2005) Structure of an unliganded simian immunodeficiency virus gp120 core. Nature 433: 834-841.
-
(2005)
Nature
, vol.433
, pp. 834-841
-
-
Chen, B.1
Vogan, E.M.2
Gong, H.3
Skehel, J.J.4
Wiley, D.C.5
-
48
-
-
0030730243
-
Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein
-
Wyatt R, Desjardin E, Olshevsky U, Nixon C, Binley J, et al. (1997) Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein. J Virol 71: 9722-9731.
-
(1997)
J Virol
, vol.71
, pp. 9722-9731
-
-
Wyatt, R.1
Desjardin, E.2
Olshevsky, U.3
Nixon, C.4
Binley, J.5
-
49
-
-
0142211253
-
Functional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41
-
Poumbourios P, Maerz AL, Drummer HE, (2003) Functional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41. J Biol Chem 278: 42149-42160.
-
(2003)
J Biol Chem
, vol.278
, pp. 42149-42160
-
-
Poumbourios, P.1
Maerz, A.L.2
Drummer, H.E.3
-
50
-
-
22844441184
-
Alanine scanning mutants of the HIV gp41 loop
-
Jacobs A, Sen J, Rong L, Caffrey M, (2005) Alanine scanning mutants of the HIV gp41 loop. J Biol Chem 280: 27284-27288.
-
(2005)
J Biol Chem
, vol.280
, pp. 27284-27288
-
-
Jacobs, A.1
Sen, J.2
Rong, L.3
Caffrey, M.4
-
51
-
-
0036090585
-
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
-
Wei X, Decker JM, Liu H, Zhang Z, Arani RB, et al. (2002) Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrob Agents Chemother 46: 1896-1905.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1896-1905
-
-
Wei, X.1
Decker, J.M.2
Liu, H.3
Zhang, Z.4
Arani, R.B.5
-
52
-
-
0028842207
-
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
-
Connor RI, Chen BK, Choe S, Landau NR, (1995) Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology 206: 935-944.
-
(1995)
Virology
, vol.206
, pp. 935-944
-
-
Connor, R.I.1
Chen, B.K.2
Choe, S.3
Landau, N.R.4
-
53
-
-
33947600590
-
Cloning and characterization of functional subtype A HIV-1 envelope variants transmitted through breastfeeding
-
Rainwater SM, Wu X, Nduati R, Nedellec R, Mosier D, et al. (2007) Cloning and characterization of functional subtype A HIV-1 envelope variants transmitted through breastfeeding. Curr HIV Res 5: 189-197.
-
(2007)
Curr HIV Res
, vol.5
, pp. 189-197
-
-
Rainwater, S.M.1
Wu, X.2
Nduati, R.3
Nedellec, R.4
Mosier, D.5
-
54
-
-
0025268873
-
Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants
-
Helseth E, Kowalski M, Gabuzda D, Olshevsky U, Haseltine W, et al. (1990) Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants. J Virol 64: 2416-2420.
-
(1990)
J Virol
, vol.64
, pp. 2416-2420
-
-
Helseth, E.1
Kowalski, M.2
Gabuzda, D.3
Olshevsky, U.4
Haseltine, W.5
-
55
-
-
0035202616
-
Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies
-
Zwick MB, Wang M, Poignard P, Stiegler G, Katinger H, et al. (2001) Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies. J Virol 75: 12198-12208.
-
(2001)
J Virol
, vol.75
, pp. 12198-12208
-
-
Zwick, M.B.1
Wang, M.2
Poignard, P.3
Stiegler, G.4
Katinger, H.5
-
56
-
-
11144227042
-
Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1
-
Zwick MB, Jensen R, Church S, Wang M, Stiegler G, et al. (2005) Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1. J Virol 79: 1252-1261.
-
(2005)
J Virol
, vol.79
, pp. 1252-1261
-
-
Zwick, M.B.1
Jensen, R.2
Church, S.3
Wang, M.4
Stiegler, G.5
-
57
-
-
23244434512
-
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies
-
Li M, Gao F, Mascola JR, Stamatatos L, Polonis VR, et al. (2005) Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies. J Virol 79: 10108-10125.
-
(2005)
J Virol
, vol.79
, pp. 10108-10125
-
-
Li, M.1
Gao, F.2
Mascola, J.R.3
Stamatatos, L.4
Polonis, V.R.5
-
58
-
-
0037456827
-
Antibody neutralization and escape by HIV-1
-
Wei X, Decker JM, Wang S, Hui H, Kappes JC, et al. (2003) Antibody neutralization and escape by HIV-1. Nature 422: 307-312.
-
(2003)
Nature
, vol.422
, pp. 307-312
-
-
Wei, X.1
Decker, J.M.2
Wang, S.3
Hui, H.4
Kappes, J.C.5
-
59
-
-
0036260635
-
HIV type 1 variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virus
-
Long EM, Rainwater SM, Lavreys L, Mandaliya K, Overbaugh J, (2002) HIV type 1 variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virus. AIDS Res Hum Retroviruses 18: 567-576.
-
(2002)
AIDS Res Hum Retroviruses
, vol.18
, pp. 567-576
-
-
Long, E.M.1
Rainwater, S.M.2
Lavreys, L.3
Mandaliya, K.4
Overbaugh, J.5
-
60
-
-
45049083040
-
Relationship of HIV-1 and SIV envelope glycoprotein trimer occupation and neutralization
-
Crooks ET, Jiang P, Franti M, Wong S, Zwick MB, et al. (2008) Relationship of HIV-1 and SIV envelope glycoprotein trimer occupation and neutralization. Virology 377: 364-378.
-
(2008)
Virology
, vol.377
, pp. 364-378
-
-
Crooks, E.T.1
Jiang, P.2
Franti, M.3
Wong, S.4
Zwick, M.B.5
-
61
-
-
0029957230
-
Efficient infection of a human T-cell line and of human primary peripheral blood leukocytes with a pseudotyped retrovirus vector
-
Sharma S, Cantwell M, Kipps TJ, Friedmann T, (1996) Efficient infection of a human T-cell line and of human primary peripheral blood leukocytes with a pseudotyped retrovirus vector. Proc Natl Acad Sci U S A 93: 11842-11847.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 11842-11847
-
-
Sharma, S.1
Cantwell, M.2
Kipps, T.J.3
Friedmann, T.4
-
62
-
-
0028155283
-
Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization
-
Buchacher A, Predl R, Strutzenberger K, Steinfellner W, Trkola A, et al. (1994) Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization. AIDS Res Hum Retroviruses 10: 359-369.
-
(1994)
AIDS Res Hum Retroviruses
, vol.10
, pp. 359-369
-
-
Buchacher, A.1
Predl, R.2
Strutzenberger, K.3
Steinfellner, W.4
Trkola, A.5
-
63
-
-
34247106331
-
An Affinity-Enhanced Neutralizing Antibody against the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 Recognizes an Epitope between Those of 2F5 and 4E10
-
Nelson JD, Brunel FM, Jensen R, Crooks ET, Cardoso RM, et al. (2007) An Affinity-Enhanced Neutralizing Antibody against the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 Recognizes an Epitope between Those of 2F5 and 4E10. J Virol 81: 4033-4043.
-
(2007)
J Virol
, vol.81
, pp. 4033-4043
-
-
Nelson, J.D.1
Brunel, F.M.2
Jensen, R.3
Crooks, E.T.4
Cardoso, R.M.5
-
64
-
-
0037471318
-
Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base
-
Cavacini L, Duval M, Song L, Sangster R, Xiang SH, et al. (2003) Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base. Aids 17: 685-689.
-
(2003)
Aids
, vol.17
, pp. 685-689
-
-
Cavacini, L.1
Duval, M.2
Song, L.3
Sangster, R.4
Xiang, S.H.5
-
65
-
-
0026318224
-
Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI
-
Peden K, Emerman M, Montagnier L, (1991) Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI. Virology 185: 661-672.
-
(1991)
Virology
, vol.185
, pp. 661-672
-
-
Peden, K.1
Emerman, M.2
Montagnier, L.3
-
66
-
-
0037311452
-
Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTES
-
Pastore C, Picchio GR, Galimi F, Fish R, Hartley O, et al. (2003) Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTES. Antimicrob Agents Chemother 47: 509-517.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 509-517
-
-
Pastore, C.1
Picchio, G.R.2
Galimi, F.3
Fish, R.4
Hartley, O.5
-
67
-
-
33646867165
-
The production of cleaved, trimeric human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein vaccine antigens and infectious pseudoviruses using linear polyethylenimine as a transfection reagent
-
Kirschner M, Monrose V, Paluch M, Techodamrongsin N, Rethwilm A, et al. (2006) The production of cleaved, trimeric human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein vaccine antigens and infectious pseudoviruses using linear polyethylenimine as a transfection reagent. Protein Expr Purif 48: 61-68.
-
(2006)
Protein Expr Purif
, vol.48
, pp. 61-68
-
-
Kirschner, M.1
Monrose, V.2
Paluch, M.3
Techodamrongsin, N.4
Rethwilm, A.5
-
68
-
-
0032992212
-
Variants from the diverse virus population identified at seroconversion of a clade A human immunodeficiency virus type 1-infected woman have distinct biological properties
-
Poss M, Overbaugh J, (1999) Variants from the diverse virus population identified at seroconversion of a clade A human immunodeficiency virus type 1-infected woman have distinct biological properties. J Virol 73: 5255-5264.
-
(1999)
J Virol
, vol.73
, pp. 5255-5264
-
-
Poss, M.1
Overbaugh, J.2
-
69
-
-
0029655514
-
Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions
-
Freed EO, Martin MA, (1996) Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions. J Virol 70: 341-351.
-
(1996)
J Virol
, vol.70
, pp. 341-351
-
-
Freed, E.O.1
Martin, M.A.2
-
70
-
-
0028214450
-
Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis
-
Schagger H, Cramer WA, von Jagow G, (1994) Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis. Anal Biochem 217: 220-230.
-
(1994)
Anal Biochem
, vol.217
, pp. 220-230
-
-
Schagger, H.1
Cramer, W.A.2
von Jagow, G.3
-
71
-
-
0036315133
-
Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein
-
Schulke N, Vesanen MS, Sanders RW, Zhu P, Lu M, et al. (2002) Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein. J Virol 76: 7760-7776.
-
(2002)
J Virol
, vol.76
, pp. 7760-7776
-
-
Schulke, N.1
Vesanen, M.S.2
Sanders, R.W.3
Zhu, P.4
Lu, M.5
-
72
-
-
79958086672
-
Enzyme Digests Eliminate Non-Functional Env from HIV-1 Particle Surfaces Leaving Native Env Trimers Intact and Viral Infectivity Unaffected
-
In Press
-
Crooks ET, Tong T, Osawa K, Binley JM, (2011) Enzyme Digests Eliminate Non-Functional Env from HIV-1 Particle Surfaces Leaving Native Env Trimers Intact and Viral Infectivity Unaffected. J Virol In Press.
-
(2011)
J Virol
-
-
Crooks, E.T.1
Tong, T.2
Osawa, K.3
Binley, J.M.4
-
73
-
-
0041823452
-
Lipid rafts and HIV pathogenesis: virion-associated cholesterol is required for fusion and infection of susceptible cells
-
Liao Z, Graham DR, Hildreth JE, (2003) Lipid rafts and HIV pathogenesis: virion-associated cholesterol is required for fusion and infection of susceptible cells. AIDS Res Hum Retroviruses 19: 675-687.
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, pp. 675-687
-
-
Liao, Z.1
Graham, D.R.2
Hildreth, J.E.3
-
74
-
-
0026356172
-
Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes
-
Westervelt P, Gendelman HE, Ratner L, (1991) Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes. Proc Natl Acad Sci U S A 88: 3097-3101.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 3097-3101
-
-
Westervelt, P.1
Gendelman, H.E.2
Ratner, L.3
-
75
-
-
0023898273
-
Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes
-
Gendelman HE, Orenstein JM, Martin MA, Ferrua C, Mitra R, et al. (1988) Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes. J Exp Med 167: 1428-1441.
-
(1988)
J Exp Med
, vol.167
, pp. 1428-1441
-
-
Gendelman, H.E.1
Orenstein, J.M.2
Martin, M.A.3
Ferrua, C.4
Mitra, R.5
-
76
-
-
0023214674
-
Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms
-
Koyanagi Y, Miles S, Mitsuyasu RT, Merrill JE, Vinters HV, et al. (1987) Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236: 819-822.
-
(1987)
Science
, vol.236
, pp. 819-822
-
-
Koyanagi, Y.1
Miles, S.2
Mitsuyasu, R.T.3
Merrill, J.E.4
Vinters, H.V.5
-
77
-
-
0032980413
-
A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity
-
Salzwedel K, West JT, Hunter E, (1999) A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity. J Virol 73: 2469-2480.
-
(1999)
J Virol
, vol.73
, pp. 2469-2480
-
-
Salzwedel, K.1
West, J.T.2
Hunter, E.3
-
78
-
-
0029836434
-
Increased envelope spike density and stability are not required for the neutralization resistance of primary human immunodeficiency viruses
-
Karlsson GB, Gao F, Robinson J, Hahn B, Sodroski J, (1996) Increased envelope spike density and stability are not required for the neutralization resistance of primary human immunodeficiency viruses. J Virol 70: 6136-6142.
-
(1996)
J Virol
, vol.70
, pp. 6136-6142
-
-
Karlsson, G.B.1
Gao, F.2
Robinson, J.3
Hahn, B.4
Sodroski, J.5
-
79
-
-
70350320690
-
Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachment
-
Wu X, Zhou T, O'Dell S, Wyatt RT, Kwong PD, et al. (2009) Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachment. J Virol 83: 10892-10907.
-
(2009)
J Virol
, vol.83
, pp. 10892-10907
-
-
Wu, X.1
Zhou, T.2
O'Dell, S.3
Wyatt, R.T.4
Kwong, P.D.5
-
80
-
-
0038076112
-
Redox-triggered infection by disulfide-shackled human immunodeficiency virus type 1 pseudovirions
-
Binley JM, Cayanan CS, Wiley C, Schulke N, Olson WC, et al. (2003) Redox-triggered infection by disulfide-shackled human immunodeficiency virus type 1 pseudovirions. J Virol 77: 5678-5684.
-
(2003)
J Virol
, vol.77
, pp. 5678-5684
-
-
Binley, J.M.1
Cayanan, C.S.2
Wiley, C.3
Schulke, N.4
Olson, W.C.5
-
81
-
-
66149136375
-
Identification of a human immunodeficiency virus type 1 envelope glycoprotein variant resistant to cold inactivation
-
Kassa A, Finzi A, Pancera M, Courter JR, Smith AB 3rd, et al. (2009) Identification of a human immunodeficiency virus type 1 envelope glycoprotein variant resistant to cold inactivation. J Virol 83: 4476-4488.
-
(2009)
J Virol
, vol.83
, pp. 4476-4488
-
-
Kassa, A.1
Finzi, A.2
Pancera, M.3
Courter, J.R.4
Smith III, A.B.5
-
82
-
-
69749111210
-
Increased thermostability and fidelity of DNA synthesis of wild-type and mutant HIV-1 group O reverse transcriptases
-
Alvarez M, Matamoros T, Menendez-Arias L, (2009) Increased thermostability and fidelity of DNA synthesis of wild-type and mutant HIV-1 group O reverse transcriptases. J Mol Biol 392: 872-884.
-
(2009)
J Mol Biol
, vol.392
, pp. 872-884
-
-
Alvarez, M.1
Matamoros, T.2
Menendez-Arias, L.3
-
83
-
-
0025989856
-
Blocking of human immunodeficiency virus infection depends on cell density and viral stock age
-
Layne SP, Merges MJ, Spouge JL, Dembo M, Nara PL, (1991) Blocking of human immunodeficiency virus infection depends on cell density and viral stock age. J Virol 65: 3293-3300.
-
(1991)
J Virol
, vol.65
, pp. 3293-3300
-
-
Layne, S.P.1
Merges, M.J.2
Spouge, J.L.3
Dembo, M.4
Nara, P.L.5
-
84
-
-
59749083598
-
Estimating the stoichiometry of human immunodeficiency virus entry
-
Magnus C, Rusert P, Bonhoeffer S, Trkola A, Regoes RR, (2009) Estimating the stoichiometry of human immunodeficiency virus entry. J Virol 83: 1523-1531.
-
(2009)
J Virol
, vol.83
, pp. 1523-1531
-
-
Magnus, C.1
Rusert, P.2
Bonhoeffer, S.3
Trkola, A.4
Regoes, R.R.5
-
85
-
-
0026755629
-
Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virus
-
Layne SP, Merges MJ, Dembo M, Spouge JL, Conley SR, et al. (1992) Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virus. Virology 189: 695-714.
-
(1992)
Virology
, vol.189
, pp. 695-714
-
-
Layne, S.P.1
Merges, M.J.2
Dembo, M.3
Spouge, J.L.4
Conley, S.R.5
-
86
-
-
51649128064
-
Thermostability of model protocell membranes
-
Mansy SS, Szostak JW, (2008) Thermostability of model protocell membranes. Proc Natl Acad Sci U S A 105: 13351-13355.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13351-13355
-
-
Mansy, S.S.1
Szostak, J.W.2
-
87
-
-
49049109812
-
Suboptimal inhibition of protease activity in human immunodeficiency virus type 1: effects on virion morphogenesis and RNA maturation
-
Moore MD, Fu W, Soheilian F, Nagashima K, Ptak RG, et al. (2008) Suboptimal inhibition of protease activity in human immunodeficiency virus type 1: effects on virion morphogenesis and RNA maturation. Virology 379: 152-160.
-
(2008)
Virology
, vol.379
, pp. 152-160
-
-
Moore, M.D.1
Fu, W.2
Soheilian, F.3
Nagashima, K.4
Ptak, R.G.5
-
88
-
-
52049093876
-
Moloney murine leukemia virus decay mediated by retroviral reverse transcriptase degradation of genomic RNA
-
Casali M, Zambonelli C, Goldwasser J, Vu HN, Yarmush ML, (2008) Moloney murine leukemia virus decay mediated by retroviral reverse transcriptase degradation of genomic RNA. Virology 380: 91-98.
-
(2008)
Virology
, vol.380
, pp. 91-98
-
-
Casali, M.1
Zambonelli, C.2
Goldwasser, J.3
Vu, H.N.4
Yarmush, M.L.5
-
89
-
-
73549091727
-
Asymmetric deactivation of HIV-1 gp41 following fusion inhibitor binding
-
Kahle KM, Steger HK, Root MJ, (2009) Asymmetric deactivation of HIV-1 gp41 following fusion inhibitor binding. PLoS Pathog 5: e1000674.
-
(2009)
PLoS Pathog
, vol.5
-
-
Kahle, K.M.1
Steger, H.K.2
Root, M.J.3
-
90
-
-
14644390952
-
Construction of stabilized proteins by combinatorial consensus mutagenesis
-
Amin N, Liu AD, Ramer S, Aehle W, Meijer D, et al. (2004) Construction of stabilized proteins by combinatorial consensus mutagenesis. Protein Eng Des Sel 17: 787-793.
-
(2004)
Protein Eng Des Sel
, vol.17
, pp. 787-793
-
-
Amin, N.1
Liu, A.D.2
Ramer, S.3
Aehle, W.4
Meijer, D.5
-
91
-
-
0031280508
-
Thermophilic proteins: stability and function in aqueous and organic solvents
-
Cowan DA, (1997) Thermophilic proteins: stability and function in aqueous and organic solvents. Comp Biochem Physiol A Physiol 118: 429-438.
-
(1997)
Comp Biochem Physiol A Physiol
, vol.118
, pp. 429-438
-
-
Cowan, D.A.1
-
92
-
-
0042823437
-
Regional heterogeneity of cellular prion protein isoforms in the mouse brain
-
Beringue V, Mallinson G, Kaisar M, Tayebi M, Sattar Z, et al. (2003) Regional heterogeneity of cellular prion protein isoforms in the mouse brain. Brain 126: 2065-2073.
-
(2003)
Brain
, vol.126
, pp. 2065-2073
-
-
Beringue, V.1
Mallinson, G.2
Kaisar, M.3
Tayebi, M.4
Sattar, Z.5
-
93
-
-
79952732800
-
MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1
-
Ruprecht CR, Krarup A, Reynell L, Mann AM, Brandenberg OF, et al. (2011) MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1. J Exp Med 208: 439-454.
-
(2011)
J Exp Med
, vol.208
, pp. 439-454
-
-
Ruprecht, C.R.1
Krarup, A.2
Reynell, L.3
Mann, A.M.4
Brandenberg, O.F.5
-
94
-
-
0042389489
-
Role of the gp120 inner domain beta-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits
-
Yang X, Mahony E, Holm GH, Kassa A, Sodroski J, (2003) Role of the gp120 inner domain beta-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits. Virology 313: 117-125.
-
(2003)
Virology
, vol.313
, pp. 117-125
-
-
Yang, X.1
Mahony, E.2
Holm, G.H.3
Kassa, A.4
Sodroski, J.5
-
95
-
-
0027499917
-
Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein
-
Cao J, Bergeron L, Helseth E, Thali M, Repke H, et al. (1993) Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein. J Virol 67: 2747-2755.
-
(1993)
J Virol
, vol.67
, pp. 2747-2755
-
-
Cao, J.1
Bergeron, L.2
Helseth, E.3
Thali, M.4
Repke, H.5
-
96
-
-
4544373403
-
Role of hydrophobic residues in the central ectodomain of gp41 in maintaining the association between human immunodeficiency virus type 1 envelope glycoprotein subunits gp120 and gp41
-
York J, Nunberg JH, (2004) Role of hydrophobic residues in the central ectodomain of gp41 in maintaining the association between human immunodeficiency virus type 1 envelope glycoprotein subunits gp120 and gp41. J Virol 78: 4921-4926.
-
(2004)
J Virol
, vol.78
, pp. 4921-4926
-
-
York, J.1
Nunberg, J.H.2
-
97
-
-
33845266437
-
Structural analysis and assembly of the HIV-1 Gp41 amino-terminal fusion peptide and the pretransmembrane amphipathic-at-interface sequence
-
Lorizate M, de la Arada I, Huarte N, Sanchez-Martinez S, de la Torre BG, et al. (2006) Structural analysis and assembly of the HIV-1 Gp41 amino-terminal fusion peptide and the pretransmembrane amphipathic-at-interface sequence. Biochemistry 45: 14337-14346.
-
(2006)
Biochemistry
, vol.45
, pp. 14337-14346
-
-
Lorizate, M.1
de la Arada, I.2
Huarte, N.3
Sanchez-Martinez, S.4
de la Torre, B.G.5
-
98
-
-
79959616682
-
Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules
-
In Press
-
Gach JS, Leaman DP, Zwick M, (2011) Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules. Curr Top Med Chem In Press.
-
(2011)
Curr Top Med Chem
-
-
Gach, J.S.1
Leaman, D.P.2
Zwick, M.3
-
99
-
-
0346220015
-
Peptide-induced formation of cholesterol-rich domains
-
Epand RM, Sayer BG, Epand RF, (2003) Peptide-induced formation of cholesterol-rich domains. Biochemistry 42: 14677-14689.
-
(2003)
Biochemistry
, vol.42
, pp. 14677-14689
-
-
Epand, R.M.1
Sayer, B.G.2
Epand, R.F.3
-
100
-
-
69249202492
-
Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain
-
Kassa A, Madani N, Schon A, Haim H, Finzi A, et al. (2009) Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain. J Virol 83: 8364-8378.
-
(2009)
J Virol
, vol.83
, pp. 8364-8378
-
-
Kassa, A.1
Madani, N.2
Schon, A.3
Haim, H.4
Finzi, A.5
-
101
-
-
77749329921
-
Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions
-
Finzi A, Xiang SH, Pacheco B, Wang L, Haight J, et al. (2010) Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions. Mol Cell 37: 656-667.
-
(2010)
Mol Cell
, vol.37
, pp. 656-667
-
-
Finzi, A.1
Xiang, S.H.2
Pacheco, B.3
Wang, L.4
Haight, J.5
-
102
-
-
19444376783
-
Neutralization sensitivity of HIV-1 Env-pseudotyped virus clones is determined by co-operativity between mutations which modulate the CD4-binding site and those that affect gp120-gp41 stability
-
Beddows S, Zheng NN, Herrera C, Michael E, Barnes K, et al. (2005) Neutralization sensitivity of HIV-1 Env-pseudotyped virus clones is determined by co-operativity between mutations which modulate the CD4-binding site and those that affect gp120-gp41 stability. Virology 337: 136-148.
-
(2005)
Virology
, vol.337
, pp. 136-148
-
-
Beddows, S.1
Zheng, N.N.2
Herrera, C.3
Michael, E.4
Barnes, K.5
-
103
-
-
41149099165
-
Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors
-
Peters PJ, Duenas-Decamp MJ, Sullivan WM, Brown R, Ankghuambom C, et al. (2008) Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors. Retrovirology 5: 5.
-
(2008)
Retrovirology
, vol.5
, pp. 5
-
-
Peters, P.J.1
Duenas-Decamp, M.J.2
Sullivan, W.M.3
Brown, R.4
Ankghuambom, C.5
-
104
-
-
0037059049
-
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
-
Reeves JD, Gallo SA, Ahmad N, Miamidian JL, Harvey PE, et al. (2002) Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proc Natl Acad Sci U S A 99: 16249-16254.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 16249-16254
-
-
Reeves, J.D.1
Gallo, S.A.2
Ahmad, N.3
Miamidian, J.L.4
Harvey, P.E.5
-
105
-
-
0030023304
-
Neutralizing antibodies to human immunodeficiency virus type-1 gp120 induce envelope glycoprotein subunit dissociation
-
Poignard P, Fouts T, Naniche D, Moore JP, Sattentau QJ, (1996) Neutralizing antibodies to human immunodeficiency virus type-1 gp120 induce envelope glycoprotein subunit dissociation. J Exp Med 183: 473-484.
-
(1996)
J Exp Med
, vol.183
, pp. 473-484
-
-
Poignard, P.1
Fouts, T.2
Naniche, D.3
Moore, J.P.4
Sattentau, Q.J.5
-
106
-
-
26844552845
-
Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy
-
Popovic M, Tenner-Racz K, Pelser C, Stellbrink HJ, van Lunzen J, et al. (2005) Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy. Proc Natl Acad Sci U S A 102: 14807-14812.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14807-14812
-
-
Popovic, M.1
Tenner-Racz, K.2
Pelser, C.3
Stellbrink, H.J.4
van Lunzen, J.5
-
107
-
-
70349326548
-
HIV-1 envelope protein gp120 is present at high concentrations in secondary lymphoid organs of individuals with chronic HIV-1 infection
-
Santosuosso M, Righi E, Lindstrom V, Leblanc PR, Poznansky MC, (2009) HIV-1 envelope protein gp120 is present at high concentrations in secondary lymphoid organs of individuals with chronic HIV-1 infection. J Infect Dis 200: 1050-1053.
-
(2009)
J Infect Dis
, vol.200
, pp. 1050-1053
-
-
Santosuosso, M.1
Righi, E.2
Lindstrom, V.3
Leblanc, P.R.4
Poznansky, M.C.5
-
108
-
-
77954042425
-
Few and far between: how HIV may be evading antibody avidity
-
Klein JS, Bjorkman PJ, (2010) Few and far between: how HIV may be evading antibody avidity. PLoS Pathog 6: e1000908.
-
(2010)
PLoS Pathog
, vol.6
-
-
Klein, J.S.1
Bjorkman, P.J.2
-
109
-
-
33745203490
-
Distribution and three-dimensional structure of AIDS virus envelope spikes
-
Zhu P, Liu J, Bess J Jr, Chertova E, Lifson JD, et al. (2006) Distribution and three-dimensional structure of AIDS virus envelope spikes. Nature 441: 847-852.
-
(2006)
Nature
, vol.441
, pp. 847-852
-
-
Zhu, P.1
Liu, J.2
Bess Jr., J.3
Chertova, E.4
Lifson, J.D.5
-
110
-
-
33947212334
-
Recirculation of germinal center B cells: a multilevel selection strategy for antibody maturation
-
Or-Guil M, Wittenbrink N, Weiser AA, Schuchhardt J, (2007) Recirculation of germinal center B cells: a multilevel selection strategy for antibody maturation. Immunol Rev 216: 130-141.
-
(2007)
Immunol Rev
, vol.216
, pp. 130-141
-
-
Or-Guil, M.1
Wittenbrink, N.2
Weiser, A.A.3
Schuchhardt, J.4
-
111
-
-
0032905728
-
Human immunodeficiency virus type 1 neutralizing antibodies accelerate clearance of cell-free virions from blood plasma
-
Igarashi T, Brown C, Azadegan A, Haigwood N, Dimitrov D, et al. (1999) Human immunodeficiency virus type 1 neutralizing antibodies accelerate clearance of cell-free virions from blood plasma. Nat Med 5: 211-216.
-
(1999)
Nat Med
, vol.5
, pp. 211-216
-
-
Igarashi, T.1
Brown, C.2
Azadegan, A.3
Haigwood, N.4
Dimitrov, D.5
-
112
-
-
33845288582
-
Complement lysis activity in autologous plasma is associated with lower viral loads during the acute phase of HIV-1 infection
-
Huber M, Fischer M, Misselwitz B, Manrique A, Kuster H, et al. (2006) Complement lysis activity in autologous plasma is associated with lower viral loads during the acute phase of HIV-1 infection. PLoS Med 3: e441.
-
(2006)
PLoS Med
, vol.3
-
-
Huber, M.1
Fischer, M.2
Misselwitz, B.3
Manrique, A.4
Kuster, H.5
|