Variants from the diverse virus population identified at seroconversion of a clade A human immunodeficiency virus type 1-infected woman have distinct biological properties

Journal of Virology

Volumn 73, Issue 7, 1999, Pages 5255-5264

  Poss, Mary ^a,b   Overbaugh, Julie ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF MONTANA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CHIMERIC PROTEIN; TETANUS TOXOID; VIRUS ENVELOPE PROTEIN;

ANTIGEN EXPRESSION; ARTICLE; CELL PROLIFERATION; CLINICAL FEATURE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE COURSE; FEMALE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOLECULAR CLONING; MONONUCLEAR CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEROCONVERSION; SEX DIFFERENCE; STRAIN DIFFERENCE; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSMISSION;

EID: 0032992212     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.7.5255-5264.1999     Document Type: Article

References (76)

1. Adema, G. J., F. Hartgers, R. Verstraten, E. de Vries, G. Marland, S. Menon, J. Foster, Y. Xu, P. Nooyen, T. McClanahan, K. B. Bacon, and C. G. Figdor. 1997. A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 387:713-717.
2. Ager, A. 1997. Trafficking. Biochem. Soc. Trans. 25:421-428.
3. Bjellqvist, B., G. J. Hughes, C. Pasquali, N. Paquet, F. Ravier, J.-C. Sanchez, S. Frutiger, and D. F. Hochstrasser. 1993. The focusing positions of polypeptides in immobilized pH gradients can be predicted from their amino acid sequences. Electrophoresis 14:1023-1031.
4. Borthwick, N. J., M. Bofill, W. M. Gombert, A. N. Akbar, E. Medina, K. Sagawa, M. C. Lipman, M. A. Johnson, and G. Janossy. 1994. Lymphocyte activation in HIV-1 infection. II. Functional defects of CD 28- T cells. AIDS 8:431-441.
5. Brendel, V., P. Bucher, I. Nourbakhsh, B. E. Blaisdell, and S. Karlin. 1992. Methods and algorithms for statistical analysis of protein sequences. Proc. Natl. Acad. Sci. USA 89:2002-2006.
6. Bruunsgaard, H., C. Pedersen, E. Scheibel, and B. K. Pedersen. 1995. Increase in percentage of CD45RO+/CD8+ cells is associated with previous severe primary HIV infection. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 10:107-114.
7. Cameron, P. U., P. S. Freudenthal, J. M. Barker, S. Gezelter, K. Inaba, and R. M. Steinman. 1992. Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells. Science 257:383-387.
8. Cayota, A., F. Vuillier, D. Scott-Algara, V. Feuillie, and G. Dighiero. 1993. Differential requirements for HIV-1 replication in naive and memory CD4 T cells from asymptomatic HIV-1 seropositive carriers and AIDS patients. Clin. Exp. Immunol. 91:241-248.
9. Chackerian, B., L. M. Rudensey, and J. Overbaugh. 1997. Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies. J. Virol. 71:7719-7727.
10. Cimarelli, A., G. Zambruno, A. Marconi, G. Girolomoni, U. Bertazzoni, and A. Giannetti. 1994. Quantitation by competitive PCR of HIV-1 proviral DNA in epidermal Langerhans cells of HIV-infected patients. J. Acquired Immune Defic. Syndr. 7:230-235.
11. Clerici, M., N. I. Stocks, R. A. Zajac, R. N. Boswell, D. R. Lucey, C. S. Via, and G. M. Shearer. 1989. Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. J. Clin. Invest. 84:1892-1899.
12. Coffin, J. M. 1995. HIV pathogenesis. Lines drawn in epitope wars. Nature 375:534-535.
13. Croft, M., D. D. Duncan, and S. L. Swain. 1992. Response of naive antigenspecific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements. J. Exp. Med. 176:1431-1437.
14. Delwart, E. L., H. Pan, H. W. Sheppard, D. Wolpert, A. U. Neumann, and J. I. Mullins. 1997. Slower evolution of human immunodeficiency virus type 1 quasispecies during progression to AIDS. J. Virol. 71:7498-7508.
15. Delwart, E. L., H. W. Sheppard, B. D. Walker, J. Goudsmit, and J. I. Mullins. 1994. Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays. J. Virol. 68:6672-6683.
16. Delwart, E. L., E. G. Shpaer, J. Louwagie, F. E. McCutchan, M. Grez, H. Rubsamen-Waigmann, and J. I. Mullins. 1993. Genetic relationships determined by a DNA heteroduplex mobility assay: analysis of HIV-1 env genes. Science 262:1257-1261.
17. Dolan, M. J., M. Clerici, S. P. Blatt, C. W. Hendrix, G. P. Melcher, R. N. Boswell, T. M. Reeman, W. Ward, R. Hensley, and G. M. Shearer. 1995. In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus. J. Infect. Dis. 172:79-87.
18. Dubey, C., M. Croft, and S. L. Swain. 1996. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J. Immunol. 157:3280-3289.
19. Embretson, J., M. Zupancic, J. L. Ribas, A. Burke, P. Racz, K. Tenner-Racz, and A. T. Haase. 1993. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 362: 359-362.
20. Fern, J., and M. F. Good. 1992. Promiscuous malaria peptide epitope stimulates CD45Ra T cells from blood of nonexposed donors. J. Immunol. 148:907-913.
21. Finzi, D., M. Hermankova, T. Pierson, L. M. Carruth, C. Buck, R. E. Chaisson, T. C. Quinn, K. Chadwick, J. Margolick, R. Brookmeyer, J. Gallant, M. Markowitz, D. D. Ho, D. D. Richman, and R. F. Siliciano. 1997. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278:1295-1300.
22. Flechner, E. R., P. S. Freudenthal, G. Kaplan, and R. M. Steinman. 1988. Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed leukocyte reaction. Cell. Immunol. 111:183-195.
23. Frankel, S. S., B. M. Wenig, A. P. Burke, P. Mannan, L. D. R. Thompson, S. L. Abbondanzo, A. M. Nelson, M. Pope, and R. M. Steinman. 1996. Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of the adenoid. Science 272:115-117.
24. Gause, W. C., V. Mitro, C. Via, P. Linsley, J. F. Urban, Jr., and R. J. Greenwald. 1997. Do effector and memory T helper cells also need B7 ligand costimulatory signals? J. Immunol. 159:1055-1058.
25. Ginaldi, L., M. De Martinis, A. D'Ostilio, L. Marini, V. Profeta, and D. Quaglino. 1997. Activated naive and memory CD4+ and CD8- subsets in different stages of HIV infection. Pathobiology 65:91-99.
26. Groux, H., G. Torpier, D. Monté, Y. Mouton, A. Capron, and J. C. Ameisen. 1992. Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals. J. Exp. Med. 175:331-340.
27. Hansen, L. J., and S. B. Sandmeyer. 1990. Characterization of a transpositionally active Ty3 element and identification of the Ty3 integrase protein. J. Virol. 64:2599-2607.
28. Inaba, K., N. Romani, and R. M. Steinman. 1989. An antigen-independent contact mechanism as an early step in T cell-proliferative responses to dendritic cells. J. Exp. Med. 170:527-542.
29. Inaba, K., and R. M. Steinman. 1986. Accessory cell-T lymphocyte interactions: antigen-dependent and -independent clustering. J. Exp. Med. 163:247-261.
30. John, G. C., R. W. Nduati, D. Mbori-Ngacha, J. Overbaugh, M. Welch, B. A. Richardson, J. Ndinya-Achola, J. Bwayo, J. Krieger, F. Onyango, and J. K. Kreiss. 1997. Genital shedding of human immunodeficiency virus type 1 DNA during pregnancy: association with immunosuppression, abnormal cervical or vaginal discharge, and severe vitamin A deficiency. J. Infect. Dis. 175:57-62.
31. Kampinga, G. A., A. Simonon, P. Van de Perre, E. Karita, P. Msellati, and J. Goudsmit. 1997. Primary infections with HIV-1 of women and their offspring in Rwanda: findings of heterogeneity at seroconversion, coinfection, and recombinants of HIV-1 subtypes A and C. Virology 227:63-76.
32. Kanitakis, J., S. Escaich, C. Trepo, and J. Thivolet. 1991. Detection of human immunodeficiency virus-DNA and RNA in the skin of HIV-infected patients using the polymerase chain reaction. J. Investig. Dermatol. 97:91-96.
33. Kaplan, G., A. Nusrat, M. D. Witmer, I. Nath, and Z. A. Cohn. 1987. Distribution and turnover of Langerhans cells during delayed immune responses in human skin. J. Exp. Med. 165:763-776.
34. Kumar, S., K. Tamura, and M. Nei. 1994. Molecular evolutionary genetics analysis software for microcomputers. Comput. Appl. Biosci. 10:189-191.
35. Langhoff, E., E. F. Terwilliger, H. J. Bos, K. H. Kalland, M. C. Poznansky, O. M. Bacon, and W. A. Haseltine. 1991. Replication of human immunodeficiency virus type 1 in primary dendritic cell cultures. Proc. Natl. Acad. Sci. USA 88:7998-8002.
36. Leroux, C., C. J. Issel, and R. C. Montelaro. 1997. Novel and dynamic evolution of equine infectious anemia virus genomic quasispecies associated with sequential disease cycles in an experimentally infected pony. J. Virol. 71:9627-9639.
37. Levine, B. L., J. D. Mosca, J. L. Riley, R. G. Carroll, M. T. Vahey, L. L. Jagodzinski, K. F. Wagner, D. L. Mayers, D. S. Burke, O. S. Weislow, D. C. St. Louis, and C. H. June. 1996. Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation. Science 272:1939-1943.
38. Macatonia, S. E., R. Lau, S. Patterson, A. J. Pinching, and S. C. Knight. 1990. Dendritic cell infection, depletion and dysfunction in HIV-infected individuals. Immunology 71:38-45.
39. Mackay, C. R., W. Marston, and L. Dudler. 1992. Altered patterns of T cell migration through lymph nodes and skin following antigen challenge. Eur. J. Immunol. 22:2205-2210.
40. Mackay, C. R., W. L. Marston, L. Dudler, O. Spertini, T. F. Tedder, and W. R. Hein. 1992. Tissue-specific migration pathways by phenotypically distinct subpopulations of memory T cells. Eur. J. Immunol. 22:887-895.
41. Mahalingam, M., A. Pozniak, T. J. McManus, G. Senaldi, D. Vergani, and M. Peakman. 1996. Abnormalities of CD45 isoform expression in HIV infection. Clin. Immunol. Immunopathol. 81:210-214.
42. McNearney, T., Z. Hornickova, R. Markham, A. Birdwell, M. Arens, A. Saah, and L. Ratner, 1992. Relationship of human immunodeficiency virus type 1 sequence heterogeneity to stage of disease. Proc. Natl. Acad. Sci. USA 89:10247-10251.
43. Mehta, D. A., S. Markowicz, and E. G. Engleman. 1995. Generation of antigen-specific CD4+ T cell lines from naive precursors. Eur. J. Immunol. 25:1206-1211.
44. Miller, C. J., N. J. Alexander, S. Sutjipto, A. A. Lackner, A. Gettie, A. G. Hendrickx, L. J. Lowenstine, M. Jennings, and P. A. Marx. 1989. Genital mucosal transmission of simian immunodeficiency virus: animal model for heterosexual transmission of human immunodeficiency virus. J. Virol. 63: 4277-4284.
45. Miller, C. J., P. Vogel, N. J. Alexander, S. Sutjipto, A. G. Hendrickx, and P. A. Marx. 1992. Localization of SIV in the genital tract of chronically infected female rhesus macaques. Am. J. Pathol. 141:655-660.
46. Novella, I. S., E. A. Duarte, S. F. Elena, A. Moya, E. Domingo, and J. J. Holland. 1995. Exponential increases of RNA virus fitness during large population transmissions. Proc. Natl. Acad. Sci. USA 92:5841-5844.
47. Ostrowski, M. A., S. K. Stanley, J. S. Justement, K. Gantt, D. Goletti, and A. S. Fauci. 1997. Increased in vitro tetanus-induced production of HIV type 1 following in vivo immunization of HIV type 1-infected individuals with tetanus toxoid. AIDS Res. Hum. Retroviruses 13:473-480.
48. Pantaleo, G., C. Graziosi, J. F. Demarest, L. Butini, M. Montroni, C. H. Fox, J. M. Orenstein, D. P. Kotler, and A. S. Fauci. 1993. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 362:355-358.
49. Pinchuk, L. M., P. S. Polacino, M. B. Agy, S. J. Klaus, and E. A. Clark. 1994. The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection. Immunity 1:317-325.
50. Pope, M., M. G. H. Betjes, N. Romani, H. Hirmand, P. U. Cameron, L. Hoffman, S. Gezelter, G. Schuler, and R. M. Steinman. 1994. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell 78:389-398.
51. Poss, M., J. Gosink, E. Thomas, J. K. Kreiss, J. Ndinya-Achola, K. Mandaliya, J. Bwayo, and J. Overbaugh. 1997. Phylogenetic evaluation of Kenyan HIV-1 isolates. AIDS Res. Hum. Retroviruses 13:493-499.
52. Poss, M., H. Martin, J. Kreiss, P. Nyange, K. Mandaliya, B. Chohan, and J. Overbaugh. 1995. Diversity in virus populations from genital mucosa and peripheral blood in women recently infected with human immunodeficiency virus. J. Virol. 69:8118-8122.
53. Poss, M., A. G. Rodrigo, J. J. Gosink, G. H. Learn, D. D. Panteleeff, H. L. Martin Jr., J. Bwayo, J. K. Kreiss, and J. Overbaugh. 1998. Evolution of envelope sequences from the genital tract and peripheral blood of women infected with clade A human immunodeficiency virus type 1. J. Virol. 72: 8240-8251.
54. Roederer, M., P. A. Raju, D. K. Mitra, L. A. Herzenberg, and L. A. Herzenberg. 1997. HIV does not replicate in naive CD4 T cells stimulated with CD3/CD28. J. Clin. Investig. 99:1555-1564.
55. Romani, N., S. Gruner, D. Brang, E. Kampgen, A. Lenz, B. Trockenbacher, G. Konwalinka, P. O. Fritsch, R. M. Steinman, and G. Schuler. 1994. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180:83-93.
56. Roos, M. T., J. M. Lange, R. E. de Goede, R. A. Coutinho, P. T. Schellekens, F. Miedema, and M. Tersmette. 1992. Viral phenotype and immune response in primary human immunodeficiency virus type 1 infection. J. Infect. Dis. 165:427-432.
57. Schnittman, S. M., H. C. Lane, J. Greenhouse, J. S. Justement, M. Baseler, and A. S. Fauci. 1990. Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc. Natl. Acad. Sci. USA 87:6058-6062.
58. Schuitemaker, H., M. Koot, N. A. Kootstra, M. W. Dercksen, R. E. de Goede, R. P. van Steenwijk, J. M. Lange, J. K. M. Eeftink Schattenkerk, F. Miedema, and M. Tersmette. 1992. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population. J. Virol. 66:1354-1360.
59. Schuitemaker, H., N. A. Kootstra, R. E. de Goudl, F. de Wolf, F. Miedema, and M. Tersmette. 1991. Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture. J. Virol. 65:356-363.
60. Sleasman, J. W., L. F. Aleixo, A. Morton, S. Skoda-Smith, and M. M. Goodenow. 1996. CD4+ memory T cells are the predominant population of HIV-1-infected lymphocytes in neonates and children. AIDS 10:1477-1484.
61. Spina, C. A., J. C. Guatelli, and D. D. Richman. 1995. Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro. J. Virol. 69:2977-2988.
62. Spira, A. I., P. A. Marx, B. K. Patterson, J. Mahoney, R. A. Koup, S. M. Wokinsky, and D. D. Ho. 1996. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J. Exp. Med. 183:215-225.
63. Stanley, S. K., M. A. Ostrowski, J. S. Justement, K. Gantt, S. Hedayati, M. Mannix, K. Roche, D. J. Schwartzentruber, C. H. Fox, and A. S. Fauci. 1996. Effect of immunization with a common recall antigen on viral expression in patients infected with human immunodeficiency virus type 1. N. Engl. J. Med. 334:1222-1230.
64. Steinman, R. M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9:271-296.
65. Tersmette, M., R. E. Y. de Goede, B. J. M. Al, I. N. Winkel, R. A. Gruters, H. T. Cuypers, H. G. Huisman, and F. Miedema. 1988. Differential syncytium-inducing capacity of human immunodeficiency virus isolate: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. J. Virol. 62:2026-2032.
66. Tersmette, M., R. A. Gruters, F. de Wolf, R. E. Y. de Goede, J. M. A. Lange, P. T. A. Schellekens, J. Goudsmit, H. G. Huisman, and F. Miedema. 1989. Evidence for a role of virulent human immunodeficiency virus (HIV) in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates. J. Virol. 63:2118-2125.
67. van Noesel, C. J. M., R. A. Gruters, F. G. Terpstra, P. T. A. Schellekens, R. A. W. van Lier, and F. Miedema. 1990. Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus-infected men. J. Clin. Investig. 86:293-299.
68. van'T Wout, A. B., N. A. Kootstra, G. A. Mulder-Kampinga, N. Albrecht-van Lent, H. J. Scherpbier, J. Veenstra, K. Boer, R. A. Coutinho, F. Miedema, and H. Schuitemaker. 1994. Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral and vertical transmission. J. Clin. Investig. 94:2060-2067.
69. Weissman, D., J. Daucher, T. Barker, J. Adelsberger, M. Baseler, and A. S. Fauci. 1996. Cytokine regulation of HIV replication induced by dendritic cell-CD4-positive T cell interactions. AIDS Res. Hum. Retroviruses 12:759-767.
70. Weissman, D., Y. Li, J. M. Orenstein, and A. S. Fauci. 1995. Both a precursor and a mature population of dendritic cells can bind HIV. J. Immunol. 155:4111-4117.
71. Wolfs, T. F., G. Zwart, M. Bakker, and J. Goudsmit. 1992. HIV-1 genomic RNA diversification following sexual and parenteral virus transmission. Virology 189:103-110.
72. Wolinsky, S. M., B. T. M. Korber, A. U. Neumann, M. Daniels, K. J. Kunstman, A. J. Whetsell, M. R. Furtado, Y. Cao, D. D. Ho, J. T. Safrit, and R. A. Koup. 1996. Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection. Science 272:537-542.
73. Wong, J. K., M. Hezareh, H. F. Gunthard, D. V. Havlir, C. C. Ignacio, C. A. Spina, and D. D. Richman. 1997. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 278:1291-1295.
74. Woods, T. C., B. D. Roberts, S. T. Butera, and T. M. Folks. 1997. Loss of inducible virus in CD45RA naive cells after human immunodeficiency virus-1 entry accounts for preferential viral replication in CD45RO memory cells. Blood 89:1635-1641.
75. Zhang, L. Q., P. MacKenzie, A. Cleland, E. C. Holmes, A. J. Leigh Brown, and P. Simmonds. 1993. Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection. J. Virol. 67:3345-3356.
76. Zhu, T., H. Mo, N. Wang, D. S. Nam, Y. Cao, R. A. Koup, and D. D. Ho. 1993. Genotypic and phenotypic characterization of HIV-1 in patients with primary infection. Science 261:1179-1181.