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Volumn 664, Issue , 2010, Pages 165-183

Mitochondrial decay and impairment of antioxidant defenses in aging RPE cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; EXTRACELLULAR SUPEROXIDE DISMUTASE; HEAT SHOCK PROTEIN 70; UNCOUPLING PROTEIN 2;

EID: 79959593126     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-1399-9_20     Document Type: Conference Paper
Times cited : (42)

References (86)
  • 1
    • 0037331669 scopus 로고    scopus 로고
    • Flow cytometric measurement of reactive oxygen species production by normal and thalassaemic red blood cells
    • DOI 10.1034/j.1600-0609.2003.00011.x
    • Amer J, Goldfarb A, Fibach E (2003) Flow cytometric measurement of reactive oxygen species production by normal and thalassaemic red blood cells. Eur J Haematol 70:84-90 (Pubitemid 36269554)
    • (2003) European Journal of Haematology , vol.70 , Issue.2 , pp. 84-90
    • Amer, J.1    Goldfarb, A.2    Fibach, E.3
  • 2
    • 33645420460 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization: The sine qua non for cell death
    • Armstrong JS (2006) Mitochondrial membrane permeabilization: The sine qua non for cell death. Bioessays 28:253-260
    • (2006) Bioessays , vol.28 , pp. 253-260
    • Armstrong, J.S.1
  • 3
    • 4544322045 scopus 로고    scopus 로고
    • Free radicals and aging
    • DOI 10.1016/j.tins.2004.07.005, PII S0166223604002334
    • Barja G (2004) Free radicals and aging. Trends Neurosci 27:595-600 (Pubitemid 39221395)
    • (2004) Trends in Neurosciences , vol.27 , Issue.10 , pp. 595-600
    • Barja, G.1
  • 4
    • 0032504710 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases
    • DOI 10.1016/S0005-2728(98)00114-5, PII S0005272898001145
    • Beal MF (1998) Mitochondrial dysfunction in neurodegenerative diseases. Biochim Biophys Acta 1366:211-223 (Pubitemid 28467033)
    • (1998) Biochimica et Biophysica Acta - Bioenergetics , vol.1366 , Issue.1-2 , pp. 211-223
    • Beal, M.F.1
  • 5
    • 38449118776 scopus 로고    scopus 로고
    • Mitochondria and neurodegeneration
    • discussion 192-196
    • Beal MF (2007) Mitochondria and neurodegeneration. Novartis Found Symp 287:183-192 discussion 192-196
    • (2007) Novartis Found Symp , vol.287 , pp. 183-192
    • Beal, M.F.1
  • 6
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • Beatty S, Koh H, Phil M et al (2000) The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 45:115-134
    • (2000) Surv Ophthalmol , vol.45 , pp. 115-134
    • Beatty, S.1    Koh, H.2    Phil, M.3
  • 8
    • 0028047262 scopus 로고
    • Dynamics of mitochondria in living cells: Shape changes, dislocations, fusion, and fission of mitochondria
    • Bereiter-Hahn J, Vöth M (1994) Dynamics of mitochondria in living cells: Shape changes, dislocations, fusion, and fission of mitochondria. Microsc Res Tech 27:198-219 (Pubitemid 24062014)
    • (1994) Microscopy Research and Technique , vol.27 , Issue.3 , pp. 198-219
    • Bereiter-Hahn, J.1    Voth, M.2
  • 11
    • 0035181847 scopus 로고    scopus 로고
    • Quantitative cytochemical mapping of mitochondrial enzymes in rat cerebella
    • DOI 10.1016/S0968-4328(00)00015-9, PII S0968432800000159
    • Bertoni-Freddari C, Fattoretti P, Casoli T et al (2001) Quantitative cytochemical mapping of mitochondrial enzymes in rat cerebella. Micron 32:405-410 (Pubitemid 32062529)
    • (2001) Micron , vol.32 , Issue.4 , pp. 405-410
    • Bertoni-Freddari, C.1    Fattoretti, P.2    Casoli, T.3    Di Stefano, G.4    Solazzi, M.5    Meier-Ruge, W.6
  • 13
    • 0037292417 scopus 로고    scopus 로고
    • Inverse correlation between mitochondrial size and metabolic competence: A quantitative cytochemical study of cytochrome oxidase activity
    • Bertoni-Freddari C, Fattoretti P, Paoloni R et al (2003) Inverse correlation between mitochondrial size and metabolic competence: A quantitative cytochemical study of cytochrome oxidase activity. Naturwissenschaften 90:68-71 (Pubitemid 36286902)
    • (2003) Naturwissenschaften , vol.90 , Issue.2 , pp. 68-71
    • Bertoni-Freddari, C.1    Fattoretti, P.2    Paoloni, R.3    Caselli, U.4    Giorgetti, B.5    Solazzi, M.6
  • 14
    • 38049059966 scopus 로고    scopus 로고
    • DNA damage, cellular senescence and organismal ageing: Causal or correlative?
    • Chen JH, Hales CN, Ozanne SE (2007) DNA damage, cellular senescence and organismal ageing: Causal or correlative? Nucleic Acids Res 35:7417-7428
    • (2007) Nucleic Acids Res , vol.35 , pp. 7417-7428
    • Chen, J.H.1    Hales, C.N.2    Ozanne, S.E.3
  • 15
    • 33846051882 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and Alzheimer's disease
    • DOI 10.2174/156720506779025215
    • Chen X, Stern D, Yan SD (2006) Mitochondrial dysfunction and Alzheimer's disease. Curr Alzheimer Res 3:515-520 (Pubitemid 46066427)
    • (2006) Current Alzheimer Research , vol.3 , Issue.5 , pp. 515-520
    • Chen, X.1    Stern, D.2    Shi, D.Y.3
  • 16
    • 36048981446 scopus 로고    scopus 로고
    • Role of mitochondria in reactive oxygen species generation and removal; relevance to signaling and programmed cell death
    • Czarna M, Jarmuszkiewicz W (2006) Role of mitochondria in reactive oxygen species generation and removal; relevance to signaling and programmed cell death. Postepy Biochem 52: 145-156
    • (2006) Postepy Biochem , vol.52 , pp. 145-156
    • Czarna, M.1    Jarmuszkiewicz, W.2
  • 17
    • 33645244135 scopus 로고    scopus 로고
    • Combined modulation of the mitochondrial ATPdependent potassium channel and the permeability transition pore causes prolongation of the biphasic calcium dynamics
    • Dahlem YA, Wolf G, Siemen D et al (2006) Combined modulation of the mitochondrial ATPdependent potassium channel and the permeability transition pore causes prolongation of the biphasic calcium dynamics. Cell Calcium 39:387-400
    • (2006) Cell Calcium , vol.39 , pp. 387-400
    • Dahlem, Y.A.1    Wolf, G.2    Siemen, D.3
  • 19
    • 0036024976 scopus 로고    scopus 로고
    • Measuring mitochondrial reactive oxygen species
    • DOI 10.1016/S1046-2023(02)00039-7, PII S1046202302000397
    • Degli Esposti M (2002) Measuring mitochondrial reactive oxygen species. Methods 26:335-340 (Pubitemid 34971573)
    • (2002) Methods , vol.26 , Issue.4 , pp. 335-340
    • Degli Esposti, M.1
  • 20
    • 33645831566 scopus 로고    scopus 로고
    • The apoptotic effect of brucine from the seed of Strychnos nux-vomica on human hepatoma cells is mediated via Bcl-2 and Ca2+ involved mitochondrial pathway
    • Deng X, Yin F, Lu X et al (2006) The apoptotic effect of brucine from the seed of Strychnos nux-vomica on human hepatoma cells is mediated via Bcl-2 and Ca2+ involved mitochondrial pathway. Toxicol Sci 91:59-69
    • (2006) Toxicol Sci , vol.91 , pp. 59-69
    • Deng, X.1    Yin, F.2    Lu, X.3
  • 22
    • 0033118649 scopus 로고    scopus 로고
    • Contributions of mitochondria to animal physiology: From homeostatic sensor to calcium signalling and cell death
    • Duchen MR (1999) Contributions of mitochondria to animal physiology: From homeostatic sensor to calcium signaling and cell death. J Physiol 16:1-17 (Pubitemid 29163987)
    • (1999) Journal of Physiology , vol.516 , Issue.1 , pp. 1-17
    • Duchen, M.R.1
  • 25
    • 33746406453 scopus 로고    scopus 로고
    • Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration
    • DOI 10.1016/j.neurobiolaging.2005.05.012, PII S0197458005001545
    • Feher J, Kovacs I, Artico M et al (2006) Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration. Neurobiol Aging 27:983-993 (Pubitemid 44262273)
    • (2006) Neurobiology of Aging , vol.27 , Issue.7 , pp. 983-993
    • Feher, J.1    Kovacs, I.2    Artico, M.3    Cavallotti, C.4    Papale, A.5    Balacco Gabrieli, C.6
  • 26
    • 34250833548 scopus 로고    scopus 로고
    • Genetic, pathogenetic, and phenotypic implications of the mitochondrial A3243G tRNALeu(UUR) mutation
    • DOI 10.1111/j.1600-0404.2007.00836.x
    • Finsterer J (2007) Genetic, pathogenetic, and phenotypic implications of the mitochondrial A3243G tRNALeu (UUR) mutation. Acta Neurol Scand 116:1-14 (Pubitemid 46976273)
    • (2007) Acta Neurologica Scandinavica , vol.116 , Issue.1 , pp. 1-14
    • Finsterer, J.1
  • 27
    • 0033757463 scopus 로고    scopus 로고
    • Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa
    • Gal A, Li Y, Thompson DA (2000) Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat Genet 26:270-271
    • (2000) Nat Genet , vol.26 , pp. 270-271
    • Gal, A.1    Li, Y.2    Thompson, D.A.3
  • 28
    • 3042591096 scopus 로고    scopus 로고
    • Cross-linking ATP synthase complexes in vivo eliminates mitochondrial cristae
    • DOI 10.1242/jcs.01074
    • Gavin PD, Prescott M, Luff SE et al (2004) Cross-linking ATP synthase complexes in vivo eliminates mitochondrial cristae. J Cell Sci 117:2333-2343 (Pubitemid 38807500)
    • (2004) Journal of Cell Science , vol.117 , Issue.11 , pp. 2333-2343
    • Gavin, P.D.1    Prescott, M.2    Luff, S.E.3    Devenish, R.J.4
  • 29
    • 0027452475 scopus 로고
    • Age-related macular degeneration histopathologic studies: The 1992 Lorenz E. Zimmerman lecture
    • Green WR, Enger C (1993) Age-related macular degeneration histopathologic studies. The 1992 Lorenz E. Zimmerman Lecture. Ophthalmology 100:1519-1535 (Pubitemid 23292863)
    • (1993) Ophthalmology , vol.100 , Issue.10 , pp. 1519-1535
    • Green, W.R.1    Enger, C.2
  • 30
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • DOI 10.1126/science.1099320
    • Green DR, Kroemer G (2004) The pathophysiology of mitochondrial cell death. Science 305: 626-629 (Pubitemid 39006738)
    • (2004) Science , vol.305 , Issue.5684 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 31
    • 0021856681 scopus 로고
    • Pathologic features of senile macular degeneration
    • Green WR, McDonnell PJ, Yeo JH (1985) Pathologic features of senile macular degeneration. Ophthalmology 92:615-627 (Pubitemid 15060973)
    • (1985) Ophthalmology , vol.92 , Issue.5 , pp. 615-627
    • Green, W.R.1    McDonnell, P.J.2    Yeo, J.H.3
  • 32
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
    • DOI 10.1016/S1350-9462(01)00010-6, PII S1350946201000106
    • Hageman GS, Luthert PJ, Victor Chong NH et al (2001) An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age related macular degeneration. Prog Retin Eye Res 20:705-732 (Pubitemid 32918285)
    • (2001) Progress in Retinal and Eye Research , vol.20 , Issue.6 , pp. 705-732
    • Hageman, G.S.1    Luthert, P.J.2    Victor Chong, N.H.3    Johnson, L.V.4    Anderson, D.H.5    Mullins, R.F.6
  • 33
    • 69249211284 scopus 로고    scopus 로고
    • Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice
    • Hauptmann S, Scherping I, Dröse S et al (2008) Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice. Neurobiol Aging Feb 21 30(10):1574-1586
    • (2008) Neurobiol Aging Feb 21 , vol.30 , Issue.10 , pp. 1574-1586
    • Hauptmann, S.1    Scherping, I.2    Dröse, S.3
  • 34
    • 52149102270 scopus 로고    scopus 로고
    • Age-related alterations of oxidative stress markers in campal CA1 sector
    • Hayakawa N, Yokoyama H, Kato H et al (2008) Age-related alterations of oxidative stress markers in campal CA1 sector. Exp Mol Pathol May 20
    • (2008) Exp Mol Pathol May 20
    • Hayakawa, N.1    Yokoyama, H.2    Kato, H.3
  • 35
    • 56149101802 scopus 로고    scopus 로고
    • Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells
    • He Y, Ge J, Tombran-Tink J (2008b) Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells. Invest Ophthalmol Vis Sci 49:4912-4922
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4912-4922
    • He, Y.1    Ge, J.2    Tombran-Tink, J.3
  • 36
    • 45549087104 scopus 로고    scopus 로고
    • Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: Protection by antioxidants
    • He Y, Tombran-Tink J, Ge J et al (2008a) Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: Protection by antioxidants. Invest Ophthalmol Vis Sci 49:1447-1458
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1447-1458
    • He, Y.1    Tombran-Tink, J.2    Ge, J.3
  • 39
    • 33748557463 scopus 로고    scopus 로고
    • 2+-release in rat sensory neurons
    • DOI 10.1152/jn.00283.2006
    • Jackson JG, Thayer SA (2006) Mitochondrial modulation of Ca2+-induced Ca2+-release in rat sensory neurons. J Neurophysiol 96:1093-1104 (Pubitemid 44371505)
    • (2006) Journal of Neurophysiology , vol.96 , Issue.3 , pp. 1093-1104
    • Jackson, J.G.1    Thayer, S.A.2
  • 40
    • 25844520458 scopus 로고    scopus 로고
    • Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism
    • DOI 10.1016/j.biocel.2005.05.013, PII S1357272505001998
    • Jezek P, Hlavatá L (2005) Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Int J Biochem Cell Biol 37:2478-2503 (Pubitemid 41400319)
    • (2005) International Journal of Biochemistry and Cell Biology , vol.37 , Issue.12 , pp. 2478-2503
    • Jezek, P.1    Hlavata, L.2
  • 41
    • 0036247932 scopus 로고    scopus 로고
    • Rod outer segments mediate mitochondrial DNA damage and apoptosis in human retinal pigment epithelium
    • DOI 10.1076/ceyr.23.1.11.5423
    • Jin GF, Hurst JS, Godley BF (2001) Rod outer segments mediate mitochondrial DNA damage and apoptosis in human retinal pigment epithelium. Curr Eye Res 23:11-19 (Pubitemid 34494009)
    • (2001) Current Eye Research , vol.23 , Issue.1 , pp. 11-19
    • Jin, G.-F.1    Hurst, J.S.2    Godley, B.F.3
  • 44
    • 34247171756 scopus 로고    scopus 로고
    • Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in Caenorhabditis elegans
    • DOI 10.1074/jbc.M609025200
    • Kimura K, Tanaka N, Nakamura N et al (2007) Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans. J Biol Chem 282:5910-5918 (Pubitemid 47093797)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.8 , pp. 5910-5918
    • Kimura, K.1    Tanaka, N.2    Nakamura, N.3    Takano, S.4    Ohkuma, S.5
  • 45
    • 13944262937 scopus 로고    scopus 로고
    • Understanding the odd science of aging
    • DOI 10.1016/j.cell.2005.01.027
    • Kirkwood TB (2005) Understanding the odd science of aging. Cell 120:437-447 (Pubitemid 40269759)
    • (2005) Cell , vol.120 , Issue.4 , pp. 437-447
    • Kirkwood, T.B.L.1
  • 46
    • 33747160762 scopus 로고    scopus 로고
    • Heteroplasmy as a common state of mitochondrial genetic information in plants and animals
    • DOI 10.1007/s00294-006-0082-1
    • Kmiec B, Woloszynska M, Janska H (2006) Heteroplasmy as a common state of mitochondrial genetic information in plants and animals. Curr Genet 50:149-159 (Pubitemid 44227695)
    • (2006) Current Genetics , vol.50 , Issue.3 , pp. 149-159
    • Kmiec, B.1    Woloszynska, M.2    Janska, H.3
  • 48
    • 0037809232 scopus 로고    scopus 로고
    • i and ADP/ATP
    • DOI 10.1074/jbc.C200703200
    • Ko YH, Delannoy M, Hullihen J et al (2003) Mitochondrial ATP synthasome. Cristaeenriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP. J Biol Chem 278: 12305-12309 (Pubitemid 36800213)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.14 , pp. 12305-12309
    • Ko, Y.H.1    Delannoy, M.2    Hullihen, J.3    Chiu, W.4    Pedersen, P.L.5
  • 50
    • 0037025256 scopus 로고    scopus 로고
    • Mitochondria, Ca2+ and neurodegenerative disease
    • Krieger C, Duchen MR (2002) Mitochondria, Ca2+ and neurodegenerative disease. Eur J Pharm. 447:177-188
    • (2002) Eur J Pharm. , vol.447 , pp. 177-188
    • Krieger, C.1    Duchen, M.R.2
  • 51
    • 37249087334 scopus 로고    scopus 로고
    • The mitochondrial respiratory chain is a modulator of apoptosis
    • DOI 10.1083/jcb.200704059
    • Kwong JQ, Henning MS, Starkov AA et al (2007) The mitochondrial respiratory chain is a modulator of apoptosis. J Cell Biol 179:1163-1177 (Pubitemid 350277736)
    • (2007) Journal of Cell Biology , vol.179 , Issue.6 , pp. 1163-1177
    • Kwong, J.Q.1    Henning, M.S.2    Starkov, A.A.3    Manfredi, G.4
  • 52
    • 0015020475 scopus 로고
    • Morphometric study of myocardial mitochondria in the rat
    • Laguens R (1971) Morphometric study of myocardial mitochondria in the rat. J Cell Biol 48: 673-676
    • (1971) J Cell Biol , vol.48 , pp. 673-676
    • Laguens, R.1
  • 53
    • 33645460107 scopus 로고    scopus 로고
    • Mitochondrial disease: Powerhouse of disease
    • Lane N (2006) Mitochondrial disease: Powerhouse of disease. Nature 440:600-602
    • (2006) Nature , vol.440 , pp. 600-602
    • Lane, N.1
  • 54
    • 0037375044 scopus 로고    scopus 로고
    • Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: A possible mechanism for RPE aging and age-related macular degeneration
    • DOI 10.1016/S0014-4835(03)00023-X
    • Liang FQ, Godley BF (2003) Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: A possible mechanism for RPE aging and age-related macular degeneration. Exp Eye Res 76:397-403 (Pubitemid 36299052)
    • (2003) Experimental Eye Research , vol.76 , Issue.4 , pp. 397-403
    • Liang, F.-Q.1    Godley, B.F.2
  • 55
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • DOI 10.1038/nature05292, PII NATURE05292
    • Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443:787-795 (Pubitemid 44622683)
    • (2006) Nature , vol.443 , Issue.7113 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 57
    • 0028321636 scopus 로고
    • Separation of phenotypically distinct subpopulations of cultured human retinal pigment epithelial cells
    • DOI 10.1006/excr.1994.1176
    • McKay BS, Burke JM (1994) Separation of phenotypically distinct subpopulations of cultured human retinal pigment epithelial cells. Exp Cell Res 213:85-92 (Pubitemid 24227386)
    • (1994) Experimental Cell Research , vol.213 , Issue.1 , pp. 85-92
    • Mckay, B.S.1    Burke, J.M.2
  • 58
    • 4544307465 scopus 로고    scopus 로고
    • Modeling mitochondrial function in aging neurons
    • DOI 10.1016/j.tins.2004.08.004, PII S0166223604002619
    • Melov S (2004) Modeling mitochondrial function in aging neurons. Trends Neurosci 27:601-606 (Pubitemid 39221396)
    • (2004) Trends in Neurosciences , vol.27 , Issue.10 , pp. 601-606
    • Melov, S.1
  • 59
    • 12844273565 scopus 로고    scopus 로고
    • 2+ release
    • DOI 10.1074/jbc.M409819200
    • Mironov SL, Ivannikov MV, Johansson M (2005) [Ca2+]i signaling between mitochondria and endoplasmic reticulum in neurons is regulated by microtubules. From mitochondrial permeability transition pore to Ca2+-induced Ca2+ release. J Biol Chem 280:715-721 (Pubitemid 40165039)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.1 , pp. 715-721
    • Mironov, S.L.1    Ivannikov, M.V.2    Johansson, M.3
  • 60
    • 48249104648 scopus 로고    scopus 로고
    • Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration
    • Nordgaard CL, Karunadharma PP, Feng X et al (2008) Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci 49:2848-2855
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 2848-2855
    • Nordgaard, C.L.1    Karunadharma, P.P.2    Feng, X.3
  • 61
    • 0036236733 scopus 로고    scopus 로고
    • Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: A homeoviscous-longevity adaptation?
    • Pamplona R, Barja G, Portero-OtínM(2002) Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: A homeoviscous-longevity adaptation? Ann N Y Acad Sci 959:475-490 (Pubitemid 34457587)
    • (2002) Annals of the New York Academy of Sciences , vol.959 , pp. 475-490
    • Pamplona, R.1    Barja, G.2    Portero-Otin, M.3
  • 62
    • 38049057905 scopus 로고    scopus 로고
    • DNA damage in telomeres and mitochondria during cellular senescence: Is there a connection?
    • Passos JF, Saretzki G, von Zglinicki T (2007) DNA damage in telomeres and mitochondria during cellular senescence: Is there a connection? Nucleic Acids Res 35:7505-7513
    • (2007) Nucleic Acids Res , vol.35 , pp. 7505-7513
    • Passos, J.F.1    Saretzki, G.2    Von Zglinicki, T.3
  • 65
    • 38149079945 scopus 로고    scopus 로고
    • Leber hereditary optic neuropathy mutations in the ND6 subunit of mitochondrial complex I affect ubiquinone reduction kinetics in a bacterial model of the enzyme
    • Pätsi J, Kervinen M, Finel M et al (2008) Leber hereditary optic neuropathy mutations in the ND6 subunit of mitochondrial complex I affect ubiquinone reduction kinetics in a bacterial model of the enzyme. Biochem J 409:129-137
    • (2008) Biochem J , vol.409 , pp. 129-137
    • Pätsi, J.1    Kervinen, M.2    Finel, M.3
  • 66
    • 48949119268 scopus 로고    scopus 로고
    • Age related mitochondrial degenerative disorders in humans
    • Reeve AK, Krishnan KJ, Turnbull DM (2008) Age related mitochondrial degenerative disorders in humans. Biotechnol J 3:750-756
    • (2008) Biotechnol J , vol.3 , pp. 750-756
    • Reeve, A.K.1    Krishnan, K.J.2    Turnbull, D.M.3
  • 67
    • 47349098337 scopus 로고    scopus 로고
    • Age-related increase of superoxide generation in the brains of mammals and birds
    • DOI 10.1111/j.1474-9726.2008.00394.x
    • Sasaki T, Unno K, Tahara S et al (2008) Age-related increase of superoxide generation in the brains of mammals and birds. Aging Cell 7:459-469 (Pubitemid 351998606)
    • (2008) Aging Cell , vol.7 , Issue.4 , pp. 459-469
    • Sasaki, T.1    Unno, K.2    Tahara, S.3    Shimada, A.4    Chiba, Y.5    Hoshino, M.6    Kaneko, T.7
  • 69
    • 0032820457 scopus 로고    scopus 로고
    • Mitochondria in the aetiology and pathogenesis of Parkinson's disease
    • DOI 10.1016/S1353-8020(99)00029-2, PII S1353802099000292
    • Schapira AH (1999) Mitochondria in the aetiology and pathogenesis of Parkinson's disease. Parkinsonism Relat Disord 5:139-143 (Pubitemid 29408667)
    • (1999) Parkinsonism and Related Disorders , vol.5 , Issue.4 , pp. 139-143
    • Schapira, A.H.V.1
  • 70
    • 0036710886 scopus 로고    scopus 로고
    • Mechanisms of aging: An appraisal of the oxidative stress hypothesis
    • DOI 10.1016/S0891-5849(02)00886-9, PII S0891584902008869
    • Sohal RS, Mockett RJ, Orr WC (2002) Mechanisms of aging: An appraisal of the oxidative stress hypothesis. Free Radic Biol Med 33:575-586 (Pubitemid 35245829)
    • (2002) Free Radical Biology and Medicine , vol.33 , Issue.5 , pp. 575-586
    • Sohal, R.S.1    Mockett, R.J.2    Orr, W.C.3
  • 72
    • 1542617769 scopus 로고    scopus 로고
    • Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP
    • DOI 10.1016/S0014-4886(03)00342-X, PII S001448860300342X
    • Song DD, Shults CW, Sisk A et al (2004) Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP. Exp Neurol 186:158-172 (Pubitemid 38333191)
    • (2004) Experimental Neurology , vol.186 , Issue.2 , pp. 158-172
    • Song, D.D.1    Shults, C.W.2    Sisk, A.3    Rockenstein, E.4    Masliah, E.5
  • 73
    • 33644992894 scopus 로고    scopus 로고
    • Mitochondrial DNA maintenance and bioenergetics
    • Stuart JA, Brown MF (2006) Mitochondrial DNA maintenance and bioenergetics. Biochim Biophys Acta 1757:79-89
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 79-89
    • Stuart, J.A.1    Brown, M.F.2
  • 74
    • 0034671726 scopus 로고    scopus 로고
    • Age-related macular degeneration: The lipofuscin component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells
    • DOI 10.1074/jbc.M007049200
    • Suter M, Remé C, Grimm C et al (2000) Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells. J Biol Chem 275:39625-39630 (Pubitemid 32058989)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 39625-39630
    • Suter, M.1    Reme, C.2    Grimm, C.3    Wenzel, A.4    Jaattela, M.5    Esser, P.6    Kociok, N.7    Leist, M.8    Richter, C.9
  • 76
    • 4544262624 scopus 로고    scopus 로고
    • 2+ regulation and gene expression in normal brain aging
    • DOI 10.1016/j.tins.2004.07.010, PII S0166223604002383
    • Toescu EC, Verkhratsky A, Landfield PW (2004) Ca2+ regulation and gene expression in normal brain aging. Trends Neurosci Oct 27(10):614-620 (Pubitemid 39221398)
    • (2004) Trends in Neurosciences , vol.27 , Issue.10 , pp. 614-620
    • Toescu, E.C.1    Verkhratsky, A.2    Landfield, P.W.3
  • 78
    • 33750737290 scopus 로고    scopus 로고
    • Role of mitochondrial oxidative stress to explain the different longevity between genders. Protective effect of estrogens
    • DOI 10.1080/10715760600952851, PII R7511T4612277244, Free Radicals in the Aging Process - The 'Free Radical Theory of Aging' 50 years after -
    • Viña J, Sastre J, Pallardó FV et al (2006) Role of mitochondrial oxidative stress to explain the different longevity between genders: Protective effect of estrogens. Free Radic Res 40: 1359-1365 (Pubitemid 44698285)
    • (2006) Free Radical Research , vol.40 , Issue.12 , pp. 1359-1365
    • Vina, J.1    Sastre, J.2    Pallardo, F.V.3    Gambini, J.4    Borras, C.5
  • 79
    • 0037686243 scopus 로고    scopus 로고
    • Megamitochondria formation - physiology and pathology
    • Wakabayashi T (2002) Megamitochondria formation - physiology and pathology. J Cell Mol Med 6:497-538
    • (2002) J Cell Mol Med , vol.6 , pp. 497-538
    • Wakabayashi, T.1
  • 80
    • 41949092130 scopus 로고    scopus 로고
    • Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid
    • Wang AL, Lukas TJ, Yuan M et al (2008) Increased mitochondrial DNA damage and downregulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid. Mol Vis 14:644-651 (Pubitemid 351513456)
    • (2008) Molecular Vision , vol.14 , pp. 644-651
    • Wang, A.L.1    Lukas, T.J.2    Yuan, M.3    Neufeld, A.H.4
  • 81
    • 0002716267 scopus 로고
    • Phototoxic changes in the retina
    • In: Miller, D (ed), Springer-Verlag, New York
    • Weiter JJ (1987) Phototoxic changes in the retina. In: Miller, D (ed) Clinical light damage to the eye. Springer-Verlag, New York
    • (1987) Clinical Light Damage to the Eye
    • Weiter, J.J.1
  • 82
    • 54149096363 scopus 로고    scopus 로고
    • Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction
    • Wenzel P, Schuhmacher S, Kienhöfer J et al (2008) Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. Cardiovasc Res July 22 80:280-289
    • (2008) Cardiovasc Res July , vol.22 , Issue.80 , pp. 280-289
    • Wenzel, P.1    Schuhmacher, S.2    Kienhöfer, J.3
  • 83
    • 0033520640 scopus 로고    scopus 로고
    • Oxidative damage and age-related macular degeneration
    • Winkler BS, Boulton ME, Gottsch JD et al (1999) Oxidative damage and age-related macular degeneration. Mol Vis 5:32
    • (1999) Mol Vis , vol.5 , pp. 32
    • Winkler, B.S.1    Boulton, M.E.2    Gottsch, J.D.3
  • 84
    • 0023224438 scopus 로고
    • Pathophysiology of age-related macular degeneration
    • DOI 10.1016/0039-6257(87)90115-9
    • Young RW (1987) Pathophysiology of age-related macular degeneration. Surv Ophthalmol 31:291-306 (Pubitemid 17076515)
    • (1987) Survey of Ophthalmology , vol.31 , Issue.5 , pp. 291-306
    • Young, R.W.1
  • 85
    • 33846889518 scopus 로고    scopus 로고
    • Naltrexone accelerates healing without compromise of adhesion complexes in normal and diabetic corneal epithelium
    • DOI 10.1016/j.brainresbull.2006.12.007, PII S0361923006003807
    • Zagon IS, Sassani JW, Myers RL et al (2007) Naltrexone accelerates healing without compromise of adhesion complexes in normal and diabetic corneal epithelium. Brain Res Bull 72:18-24 (Pubitemid 46227741)
    • (2007) Brain Research Bulletin , vol.72 , Issue.1 , pp. 18-24
    • Zagon, I.S.1    Sassani, J.W.2    Myers, R.L.3    McLaughlin, P.J.4
  • 86
    • 28744435638 scopus 로고    scopus 로고
    • Oxidative stress in ARPE-19 cultures: Do melanosomes confer cytoprotection?
    • DOI 10.1016/j.freeradbiomed.2005.08.015, PII S0891584905004612
    • Zareba M, Raciti MW, Henry MM (2006) Oxidative stress in ARPE-19 cultures: Do melanosomes confer cytoprotection? Free Radic Biol Med 40:87-100 (Pubitemid 41759406)
    • (2006) Free Radical Biology and Medicine , vol.40 , Issue.1 , pp. 87-100
    • Zareba, M.1    Raciti, M.W.2    Henry, M.M.3    Sarna, T.4    Burke, J.M.5


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