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Volumn 24, Issue 3, 2011, Pages 337-347

Etiopathogenesis of alopecia areata: Why do our patients get it?

Author keywords

alopecia areata; autoimmune disease; disease pathogenesis

Indexed keywords

AUTOANTIBODY; HEPATITIS B VACCINE; IMMUNOGLOBULIN G; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; SOYBEAN OIL;

EID: 79959558066     PISSN: 13960296     EISSN: 15298019     Source Type: Journal    
DOI: 10.1111/j.1529-8019.2011.01416.x     Document Type: Article
Times cited : (54)

References (127)
  • 1
    • 73649148718 scopus 로고    scopus 로고
    • Alopecia areata update: Part I. Clinical picture, histopathology, and pathogenesis
    • quiz 189-190
    • Alkhalifah A, Alsantali A, Wang E, McElwee KJ, Shapiro J,. Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis. J Am Acad Dermatol 2010: 62: 177-188. quiz 189-190.
    • (2010) J Am Acad Dermatol , vol.62 , pp. 177-188
    • Alkhalifah, A.1    Alsantali, A.2    Wang, E.3    McElwee, K.J.4    Shapiro, J.5
  • 4
    • 68949196138 scopus 로고    scopus 로고
    • An update on alopecia areata
    • Kos L, Conlon J,. An update on alopecia areata. Curr Opin Pediatr 2009: 21: 475-480.
    • (2009) Curr Opin Pediatr , vol.21 , pp. 475-480
    • Kos, L.1    Conlon, J.2
  • 7
    • 28744444550 scopus 로고    scopus 로고
    • Alopecia Areata: A tissue specific autoimmune disease of the hair follicle
    • DOI 10.1016/j.autrev.2005.07.001, PII S1568997205001187
    • Gilhar A, Kalish RS,. Alopecia areata: a tissue specific autoimmune disease of the hair follicle. Autoimmun Rev 2006: 5: 64-69. (Pubitemid 41759444)
    • (2006) Autoimmunity Reviews , vol.5 , Issue.1 , pp. 64-69
    • Gilhar, A.1    Kalish, R.S.2
  • 8
    • 46849083713 scopus 로고    scopus 로고
    • Alopecia areata and autoimmunity: A clinical study
    • Thomas EA, Kadyan RS,. Alopecia areata and autoimmunity: a clinical study. Indian J Dermatol 2008: 53: 70-74.
    • (2008) Indian J Dermatol , vol.53 , pp. 70-74
    • Thomas, E.A.1    Kadyan, R.S.2
  • 9
    • 35348983928 scopus 로고    scopus 로고
    • Hair loss in women
    • DOI 10.1056/NEJMcp072110
    • Shapiro J,. Clinical practice. Hair loss in women. N Engl J Med 2007: 357: 1620-1630. (Pubitemid 47598404)
    • (2007) New England Journal of Medicine , vol.357 , Issue.16 , pp. 1620-1630
    • Shapiro, J.1
  • 12
    • 0028277447 scopus 로고
    • Immunohistological study of the development of the cellular infiltrate in the pelage follicles of the DEBR model for alopecia areata
    • DOI 10.1111/j.1365-2133.1994.tb03371.x
    • Zhang JG, Oliver RF,. Immunohistological study of the development of the cellular infiltrate in the pelage follicles of the DEBR model for alopecia areata. Br J Dermatol 1994: 130: 405-414. (Pubitemid 24204657)
    • (1994) British Journal of Dermatology , vol.130 , Issue.4 , pp. 405-414
    • Zhang, J.-G.1    Oliver, R.F.2
  • 15
    • 0014807516 scopus 로고
    • Number of mast cells (MC) in Alopecia areata
    • Spath U, Steigleder GK,. Number of mast cells (MC) in Alopecia areata. Z Haut Geschlechtskr 1970: 45: 435-436.
    • (1970) Z Haut Geschlechtskr , vol.45 , pp. 435-436
    • Spath, U.1    Steigleder, G.K.2
  • 17
    • 84892335125 scopus 로고    scopus 로고
    • Alopecia areata
    • In: Whiting DAB-PU, Tosti A., Trueb R., eds. Berlin: Springer
    • Freyschmidt-Paul PMK, Hoffmann R,. Alopecia areata. In:, Whiting DAB-PU, Tosti A, Trueb R, eds. Hair growth and disorders. Berlin: Springer, 2008: 311-320.
    • (2008) Hair Growth and Disorders , pp. 311-320
    • Freyschmidt-Paul, P.M.K.1    Hoffmann, R.2
  • 18
    • 0346243854 scopus 로고    scopus 로고
    • Histopathologic Features of Alopecia Areata: A New Look
    • DOI 10.1001/archderm.139.12.1555
    • Whiting DA,. Histopathologic features of alopecia areata: a new look. Arch Dermatol 2003: 139: 1555-1559. (Pubitemid 37523073)
    • (2003) Archives of Dermatology , vol.139 , Issue.12 , pp. 1555-1559
    • Whiting, D.A.1
  • 20
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I- restricted CTLS
    • DOI 10.1038/32183
    • Albert ML, Sauter B, Bhardwaj N,. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 1998: 392: 86-89. (Pubitemid 28150594)
    • (1998) Nature , vol.392 , Issue.6671 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 22
    • 0033769951 scopus 로고    scopus 로고
    • Treatment with an anti-CD44v10-specific antibody inhibits the onset of alopecia areata in C3H/HeJ mice
    • Freyschmidt-Paul P, Seiter S, Zoller M, et al,. Treatment with an anti-CD44v10-specific antibody inhibits the onset of alopecia areata in C3H/HeJ mice. J Invest Dermatol 2000: 115: 653-657.
    • (2000) J Invest Dermatol , vol.115 , pp. 653-657
    • Freyschmidt-Paul, P.1    Seiter, S.2    Zoller, M.3
  • 24
    • 33745202583 scopus 로고    scopus 로고
    • A chronic contact eczema impedes migration of antigen-presenting cells in alopecia areata
    • Gupta P, Freyschmidt-Paul P, Vitacolonna M, et al,. A chronic contact eczema impedes migration of antigen-presenting cells in alopecia areata. J Invest Dermatol 2006: 126: 1559-1573.
    • (2006) J Invest Dermatol , vol.126 , pp. 1559-1573
    • Gupta, P.1    Freyschmidt-Paul, P.2    Vitacolonna, M.3
  • 27
    • 0031738760 scopus 로고    scopus 로고
    • Experimental induction of Alopecia areata-like hair loss in C3H/HeJ mice using a full-thickness skin grafts
    • DOI 10.1046/j.1523-1747.1998.00380.x
    • McElwee KJ, Boggess D, King LE Jr, Sundberg JP,. Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts. J Invest Dermatol 1998: 111: 797-803. (Pubitemid 28509321)
    • (1998) Journal of Investigative Dermatology , vol.111 , Issue.5 , pp. 797-803
    • McElwce, K.J.1    Boggess, D.2    King Jr., L.E.3    Sundberg, J.P.4
  • 28
    • 0032912467 scopus 로고    scopus 로고
    • Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T cells
    • DOI 10.1046/j.1365-2133.1999.02705.x
    • McElwee KJ, Spiers EM, Oliver RF,. Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T cells. Br J Dermatol 1999: 140: 432-437. (Pubitemid 29182873)
    • (1999) British Journal of Dermatology , vol.140 , Issue.3 , pp. 432-437
    • McElwee, K.J.1    Spiers, E.M.2    Oliver, R.F.3
  • 29
    • 0030003391 scopus 로고    scopus 로고
    • + T cells restores hair growth in the DEBR model for alopecia areata
    • McElwee KJ, Spiers EM, Oliver RF,. In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata. Br J Dermatol 1996: 135: 211-217. (Pubitemid 26252968)
    • (1996) British Journal of Dermatology , vol.135 , Issue.2 , pp. 211-217
    • McElwee, K.J.1    Spiers, E.M.2    Oliver, R.F.3
  • 32
    • 0036038262 scopus 로고    scopus 로고
    • Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans
    • DOI 10.1046/j.1523-1747.2002.01811.x
    • Carroll JM, McElwee KJ, E King L, Byrne MC, Sundberg JP,. Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans. J Invest Dermatol 2002: 119: 392-402. (Pubitemid 35001949)
    • (2002) Journal of Investigative Dermatology , vol.119 , Issue.2 , pp. 392-402
    • Carroll, J.M.1    McElwee, K.J.2    King Jr., L.E.3    Byrne, M.C.4    Sundberg, J.P.5
  • 33
    • 0018614032 scopus 로고
    • Direct immunofluorescence studies in alopecia areata and male pattern alopecia
    • Bystryn JC, Orentreich N, Stengel F,. Direct immunofluorescence studies in alopecia areata and male pattern alopecia. J Invest Dermatol 1979: 73: 317-320. (Pubitemid 10165032)
    • (1979) Journal of Investigative Dermatology , vol.73 , Issue.5 , pp. 317-320
    • Bystryn, J.C.1    Orentreich, N.2    Stengel, F.3
  • 34
    • 0036445565 scopus 로고    scopus 로고
    • Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle
    • DOI 10.1046/j.1523-1747.2002.19518.x
    • Bernot KM, Coulombe PA, McGowan KM,. Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol 2002: 119: 1137-1149. (Pubitemid 35430491)
    • (2002) Journal of Investigative Dermatology , vol.119 , Issue.5 , pp. 1137-1149
    • Bernot, K.M.1    Coulombe, P.A.2    McGowan, K.M.3
  • 35
    • 0142103315 scopus 로고    scopus 로고
    • Trichohyalin mechanically strengthens the hair follicle: Multiple cross-bridging roles in the inner root sheath
    • DOI 10.1074/jbc.M302037200
    • Steinert PM, Parry DA, Marekov LN,. Trichohyalin mechanically strengthens the hair follicle: multiple cross-bridging roles in the inner root shealth. J Biol Chem 2003: 278: 41409-41419. (Pubitemid 37280970)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.42 , pp. 41409-41419
    • Steinert, P.M.1    Parry, D.A.D.2    Marekov, L.N.3
  • 36
    • 77957346006 scopus 로고    scopus 로고
    • Trichohyalin is a potential major autoantigen in human alopecia areata
    • Leung MC, Sutton CW, Fenton DA, Tobin DJ,. Trichohyalin is a potential major autoantigen in human alopecia areata. J Proteome Res 2010: 9: 5153-5163.
    • (2010) J Proteome Res , vol.9 , pp. 5153-5163
    • Leung, M.C.1    Sutton, C.W.2    Fenton, D.A.3    Tobin, D.J.4
  • 37
    • 0030028886 scopus 로고    scopus 로고
    • The DEBR rat, alopecia areata and autoantibodies to the hair follicle
    • McElwee KJ, Pickett P, Oliver RF,. The DEBR rat, alopecia areata and autoantibodies to the hair follicle. Br J Dermatol 1996: 134: 55-63. (Pubitemid 26029664)
    • (1996) British Journal of Dermatology , vol.134 , Issue.1 , pp. 55-63
    • McElwee, K.J.1    Pickett, P.2    Oliver, R.F.3
  • 39
    • 0031038583 scopus 로고    scopus 로고
    • Hair follicle structures targeted by antibodies in patients with alopecia areata
    • Tobin DJ, Hann SK, Song MS, Bystryn JC,. Hair follicle structures targeted by antibodies in patients with alopecia areata. Arch Dermatol 1997: 133: 57-61. (Pubitemid 27044306)
    • (1997) Archives of Dermatology , vol.133 , Issue.1 , pp. 57-61
    • Tobin, D.J.1    Hann, S.-K.2    Song, M.-S.3    Bystryn, J.-C.4
  • 40
    • 0141818278 scopus 로고    scopus 로고
    • Characterization of hair follicle antigens targeted by the anti-hair follicle immune response
    • DOI 10.1046/j.1087-0024.2003.00805.x
    • Tobin DJ,. Characterization of hair follicle antigens targeted by the anti-hair follicle immune response. J Investig Dermatol Symp Proc 2003: 8: 176-181. (Pubitemid 37222826)
    • (2003) Journal of Investigative Dermatology Symposium Proceedings , vol.8 , Issue.2 , pp. 176-181
    • Tobin, D.J.1
  • 41
    • 0026530691 scopus 로고
    • Failure of passive transfer of serum from patients with alopecia areata and alopecia universalis to inhibit hair growth in transplants of human scalp skin grafted on to nude mice
    • Gilhar A, Pillar T, Assay B, David M,. Failure of passive transfer of serum from patients with alopecia areata and alopecia universalis to inhibit hair growth in transplants of human scalp skin grafted on to nude mice. Br J Dermatol 1992: 126: 166-171.
    • (1992) Br J Dermatol , vol.126 , pp. 166-171
    • Gilhar, A.1    Pillar, T.2    Assay, B.3    David, M.4
  • 43
    • 0021348285 scopus 로고
    • Immunohistochemical analysis of T-cell subsets in the peribulbar and intrabulbar infiltrates of alopecia areata
    • Perret C, Wiesner-Menzel L, Happle R,. Immunohistochemical analysis of T-cell subsets in the peribulbar and intrabulbar infiltrates of alopecia areata. Acta Derm Venereol 1984: 64: 26-30. (Pubitemid 14179563)
    • (1984) Acta Dermato-Venereologica , vol.64 , Issue.1 , pp. 26-30
    • Perret, C.1    Wiesner Menzel, L.2    Happle, R.3
  • 44
    • 0021279565 scopus 로고
    • Immunohistochemical and electron microscopic characterization of the cellular infiltrate in alopecia (areata, totalis, and universalis)
    • Ranki A, Kianto U, Kanerva L, Tolvanen E, Johansson E,. Immunohistochemical and electron microscopic characterization of the cellular infiltrate in alopecia (areata, totalis, and universalis). J Invest Dermatol 1984: 83: 7-11. (Pubitemid 14080891)
    • (1984) Journal of Investigative Dermatology , vol.83 , Issue.1 , pp. 7-11
    • Ranki, A.1    Kianto, U.2    Kanerva, L.3
  • 47
    • 0036277647 scopus 로고    scopus 로고
    • + regulatory T cells in C3H/HeJ mice with alopecia areata
    • DOI 10.1046/j.1523-1747.2002.01745.x
    • Zoller M, McElwee KJ, Engel P, Hoffmann R,. Transient CD44 variant isoform expression and reduction in CD4(+)/CD25(+) regulatory T cells in C3H/HeJ mice with alopecia areata. J Invest Dermatol 2002: 118: 983-992. (Pubitemid 34639176)
    • (2002) Journal of Investigative Dermatology , vol.118 , Issue.6 , pp. 983-992
    • Zoller, M.1    McElwee, K.J.2    Engel, P.3    Hoffmann, R.4
  • 48
    • 4043145727 scopus 로고    scopus 로고
    • The progressive state, in contrast to the stable or regressive state of alopecia areata, is reflected in peripheral blood mononuclear cells
    • DOI 10.1111/j.0906-6705.2004.00179.x
    • Zoller M, McElwee KJ, Vitacolonna M, Hoffmann R,. The progressive state, in contrast to the stable or regressive state of alopecia areata, is reflected in peripheral blood mononuclear cells. Exp Dermatol 2004: 13: 435-444. (Pubitemid 39077311)
    • (2004) Experimental Dermatology , vol.13 , Issue.7 , pp. 435-444
    • Zoller, M.1    McElwee, K.J.2    Vitacolonna, M.3    Hoffmann, R.4
  • 49
    • 0025755884 scopus 로고
    • Cell degeneration in alopecia areata. An ultrastructural study
    • Tobin DJ, Fenton DA, Kendall MD,. Cell degeneration in alopecia areata. An ultrastructural study. Am J Dermatopathol 1991: 13: 248-256.
    • (1991) Am J Dermatopathol , vol.13 , pp. 248-256
    • Tobin, D.J.1    Fenton, D.A.2    Kendall, M.D.3
  • 50
    • 0030764034 scopus 로고    scopus 로고
    • Morphological analysis of hair follicles in alopecia areata
    • DOI 10.1002/(SICI)1097-0029(19970815)38:4<443::AID-JEMT12>3.0.CO;2- J
    • Tobin DJ,. Morphological analysis of hair follicles in alopecia areata. Microsc Res Tech 1997: 38: 443-451. (Pubitemid 27377656)
    • (1997) Microscopy Research and Technique , vol.38 , Issue.4 , pp. 443-451
    • Tobin, D.J.1
  • 55
    • 1542379709 scopus 로고    scopus 로고
    • Collapse and Restoration of MHC Class-I-Dependent Immune Privilege: Exploiting the Human Hair Follicle as a Model
    • Ito T, Ito N, Bettermann A, Tokura Y, Takigawa M, Paus R,. Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model. Am J Pathol 2004: 164: 623-634. (Pubitemid 38364677)
    • (2004) American Journal of Pathology , vol.164 , Issue.2 , pp. 623-634
    • Ito, T.1    Ito, N.2    Bettermann, A.3    Tokura, Y.4    Takigawa, M.5    Paus, R.6
  • 57
    • 77957934923 scopus 로고    scopus 로고
    • Hair follicles from alopecia areata patients exhibit alterations in immune privilege-associated gene expression in advance of hair loss
    • Kang H, Wu WY, Lo BK, et al,. Hair follicles from alopecia areata patients exhibit alterations in immune privilege-associated gene expression in advance of hair loss. J Invest Dermatol 2010: 130: 2677-2680.
    • (2010) J Invest Dermatol , vol.130 , pp. 2677-2680
    • Kang, H.1    Wu, W.Y.2    Lo, B.K.3
  • 58
    • 0030050999 scopus 로고    scopus 로고
    • Alopecia areata: Immunohistochemistry and ultrastructure of infiltrate and identification of adhesion molecule receptors
    • Ghersetich I, Campanile G, Lotti T,. Alopecia areata: immunohistochemistry and ultrastructure of infiltrate and identification of adhesion molecule receptors. Int J Dermatol 1996: 35: 28-33. (Pubitemid 26037042)
    • (1996) International Journal of Dermatology , vol.35 , Issue.1 , pp. 28-33
    • Ghersetich, I.1    Campanile, G.2    Lotti, T.3
  • 59
    • 77957969907 scopus 로고    scopus 로고
    • Collapse of immune privilege in alopecia areata: Coincidental or substantial?
    • Gilhar A,. Collapse of immune privilege in alopecia areata: coincidental or substantial? J Invest Dermatol 2010: 130: 2535-2537.
    • (2010) J Invest Dermatol , vol.130 , pp. 2535-2537
    • Gilhar, A.1
  • 61
    • 0019457529 scopus 로고
    • Apoptosis as the mechanism of the involution of hair follicles in catagen transformation
    • Weedon D, Strutton G,. Apoptosis as the mechanism of the involution of hair follicles in catagen transformation. Acta Derm Venereol 1981: 61: 335-339. (Pubitemid 11034410)
    • (1981) Acta Dermato-Venereologica , vol.61 , Issue.4 , pp. 335-339
    • Weedon, D.1    Strutton, G.2
  • 64
    • 0014601097 scopus 로고
    • Role of macrophages in collagen resorption during hair growth cycle
    • Parakkal PF,. Role of macrophages in collagen resorption during hair growth cycle. J Ultrastruct Res 1969: 29: 210-217.
    • (1969) J Ultrastruct Res , vol.29 , pp. 210-217
    • Parakkal, P.F.1
  • 69
    • 21344468115 scopus 로고    scopus 로고
    • What can we learn from animal models of alopecia areata?
    • DOI 10.1159/000085580
    • McElwee KJ, Yu M, Park SW, Ross EK, Finner A, Shapiro J,. What can we learn from animal models of alopecia areata? Dermatology 2005: 211: 47-53. (Pubitemid 40911564)
    • (2005) Dermatology , vol.211 , Issue.1 , pp. 47-53
    • McElwee, K.J.1    Yu, M.2    Park, S.-W.3    Ross, E.K.4    Finner, A.5    Shapiro, J.6
  • 70
    • 1542706083 scopus 로고    scopus 로고
    • Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss
    • DOI 10.1354/vp.40-6-643
    • McElwee KJ, Silva K, Boggess D, Bechtold L, King LE Jr, Sundberg JP,. Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss. Vet Pathol 2003: 40: 643-650. (Pubitemid 38393537)
    • (2003) Veterinary Pathology , vol.40 , Issue.6 , pp. 643-650
    • McElwee, K.J.1    Silva, K.2    Boggess, D.3    Bechtold, L.4    King Jr., L.E.5    Sundberg, J.P.6
  • 71
    • 69949124773 scopus 로고    scopus 로고
    • History of atopy or autoimmunity increases risk of alopecia areata
    • Barahmani N, Schabath MB, Duvic M,. History of atopy or autoimmunity increases risk of alopecia areata. J Am Acad Dermatol 2009: 61: 581-591.
    • (2009) J Am Acad Dermatol , vol.61 , pp. 581-591
    • Barahmani, N.1    Schabath, M.B.2    Duvic, M.3
  • 72
    • 0036190728 scopus 로고    scopus 로고
    • k-restricted epitope in the Tax protein of human T-lymphotropic virus type I is enhanced by the proteasome inhibitor lactacystin
    • Lomas M, Hanon E, Tanaka Y, Bangham CR, Gould KG,. Presentation of a new H-2D(k)-restricted epitope in the Tax protein of human T-lymphotropic virus type I is enhanced by the proteasome inhibitor lactacystin. J Gen Virol 2002: 83: 641-650. (Pubitemid 34183009)
    • (2002) Journal of General Virology , vol.83 , Issue.3 , pp. 641-650
    • Lomas, M.1    Hanon, E.2    Tanaka, Y.3    Bangham, C.R.M.4    Gould, K.G.5
  • 73
    • 0013833758 scopus 로고
    • A new classification of alopecia areata
    • Ikeda T,. A new classification of alopecia areata. Dermatologica 1965: 131: 421-445.
    • (1965) Dermatologica , vol.131 , pp. 421-445
    • Ikeda, T.1
  • 74
    • 33645230914 scopus 로고    scopus 로고
    • The epidemiology of childhood alopecia areata in China: A study of 226 patients
    • Xiao FL, Yang S, Liu JB, et al,. The epidemiology of childhood alopecia areata in China: a study of 226 patients. Pediatr Dermatol 2006: 23: 13-18.
    • (2006) Pediatr Dermatol , vol.23 , pp. 13-18
    • Xiao, F.L.1    Yang, S.2    Liu, J.B.3
  • 75
    • 0036861512 scopus 로고    scopus 로고
    • Alopecia areata in children: A clinical profile
    • DOI 10.1046/j.1525-1470.2002.00215.x
    • Nanda A, Al-Fouzan AS, Al-Hasawi F,. Alopecia areata in children: a clinical profile. Pediatr Dermatol 2002: 19: 482-485. (Pubitemid 35425144)
    • (2002) Pediatric Dermatology , vol.19 , Issue.6 , pp. 482-485
    • Nanda, A.1    Al-Fouzan, A.S.2    Al-Hasawi, F.3
  • 76
    • 33748894922 scopus 로고    scopus 로고
    • Profile of 513 patients with alopecia areata: Associations of disease subtypes with atopy, autoimmune disease and positive family history
    • DOI 10.1111/j.1468-3083.2006.01676.x
    • Goh C, Finkel M, Christos PJ, Sinha AA,. Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history. J Eur Acad Dermatol Venereol 2006: 20: 1055-1060. (Pubitemid 44425959)
    • (2006) Journal of the European Academy of Dermatology and Venereology , vol.20 , Issue.9 , pp. 1055-1060
    • Goh, C.1    Finkel, M.2    Christos, P.J.3    Sinha, A.A.4
  • 77
    • 0028277331 scopus 로고
    • Increased risk for type I (insulin-dependent) diabetes in relatives of patients with alopecia areata (AA)
    • DOI 10.1002/ajmg.1320510313
    • Wang SJ, Shohat T, Vadheim C, Shellow W, Edwards J, Rotter JI,. Increased risk for type I (insulin-dependent) diabetes in relatives of patients with alopecia areata (AA). Am J Med Genet 1994: 51: 234-239. (Pubitemid 24184458)
    • (1994) American Journal of Medical Genetics , vol.51 , Issue.3 , pp. 234-239
    • Wang, S.-J.1    Shohat, T.2    Vadheim, C.3    Shellow, W.4    Edwards, J.5    Rotter, J.I.6
  • 78
    • 0036307544 scopus 로고    scopus 로고
    • Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity
    • Elenkov IJ, Chrousos GP,. Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann N Y Acad Sci 2002: 966: 290-303. (Pubitemid 34729188)
    • (2002) Annals of the New York Academy of Sciences , vol.966 , pp. 290-303
    • Elenkov, I.J.1    Chrousos, G.P.2
  • 79
    • 0035187388 scopus 로고    scopus 로고
    • Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata
    • DOI 10.1034/j.1600-0625.2001.100605.x
    • McElwee KJ, Silva K, Beamer WG, King LE Jr, Sundberg JP,. Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata. Exp Dermatol 2001: 10: 420-429. (Pubitemid 33080993)
    • (2001) Experimental Dermatology , vol.10 , Issue.6 , pp. 420-429
    • McElwee, K.J.1    Silva, K.2    Beamer, W.G.3    King Jr., L.E.4    Sundberg, J.P.5
  • 81
    • 45049084949 scopus 로고    scopus 로고
    • Onset of alopecia areata after Epstein-Barr virus infectious mononucleosis
    • Rodriguez TA, Duvic M,. Onset of alopecia areata after Epstein-Barr virus infectious mononucleosis. J Am Acad Dermatol 2008: 59: 137-139.
    • (2008) J Am Acad Dermatol , vol.59 , pp. 137-139
    • Rodriguez, T.A.1    Duvic, M.2
  • 82
    • 0014036223 scopus 로고
    • Produced alopecia areata based on the focal infection theory and mental motive theory
    • Ikeda T,. Produced alopecia areata based on the focal infection theory and mental motive theory. Dermatologica 1967: 134: 1-11.
    • (1967) Dermatologica , vol.134 , pp. 1-11
    • Ikeda, T.1
  • 84
    • 0030752856 scopus 로고    scopus 로고
    • Stress and alopecia areata: A psychodermatologic study
    • Gupta MA, Gupta AK, Watteel GN,. Stress and alopecia areata: a psychodermatologic study. Acta Derm Venereol 1997: 77: 296-298. (Pubitemid 27286464)
    • (1997) Acta Dermato-Venereologica , vol.77 , Issue.4 , pp. 296-298
    • Gupta, M.A.1    Gupta, A.K.2    Watteel, G.N.3
  • 87
    • 0029037126 scopus 로고
    • The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
    • Chrousos GP,. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med 1995: 332: 1351-1362.
    • (1995) N Engl J Med , vol.332 , pp. 1351-1362
    • Chrousos, G.P.1
  • 88
    • 33846953200 scopus 로고    scopus 로고
    • A case series of alopecia areata in children: Impact of personal and family history of stress and autoimmunity
    • Kakourou T, Karachristou K, Chrousos G,. A case series of alopecia areata in children: impact of personal and family history of stress and autoimmunity. J Eur Acad Dermatol Venereol 2007: 21: 356-359.
    • (2007) J Eur Acad Dermatol Venereol , vol.21 , pp. 356-359
    • Kakourou, T.1    Karachristou, K.2    Chrousos, G.3
  • 89
    • 0942266093 scopus 로고    scopus 로고
    • Roles of Stress, Stress Perception and Trait-Anxiety in the Onset and Course of Alopecia Areata
    • Brajac I, Tkalcic M, Dragojevic DM, Gruber F,. Roles of stress, stress perception and trait-anxiety in the onset and course of alopecia areata. J Dermatol 2003: 30: 871-878. (Pubitemid 38139976)
    • (2003) Journal of Dermatology , vol.30 , Issue.12 , pp. 871-878
    • Brajac, I.1    Tkalcic, M.2    Dragojevic, D.M.3    Gruber, F.4
  • 91
    • 0026742365 scopus 로고
    • Can alopecia areata be triggered by emotional stress? An uncontrolled evaluation of 178 patients with extensive hair loss
    • van der Steen P, Boezeman J, Duller P, Happle R,. Can alopecia areata be triggered by emotional stress? An uncontrolled evaluation of 178 patients with extensive hair loss. Acta Derm Venereol 1992: 72: 279-280.
    • (1992) Acta Derm Venereol , vol.72 , pp. 279-280
    • Van Der Steen, P.1    Boezeman, J.2    Duller, P.3    Happle, R.4
  • 92
    • 66149140289 scopus 로고    scopus 로고
    • Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model
    • Zhang X, Yu M, Yu W, Weinberg J, Shapiro J, McElwee KJ,. Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model. J Invest Dermatol 2009: 129: 1527-1538.
    • (2009) J Invest Dermatol , vol.129 , pp. 1527-1538
    • Zhang, X.1    Yu, M.2    Yu, W.3    Weinberg, J.4    Shapiro, J.5    McElwee, K.J.6
  • 93
    • 0035743066 scopus 로고    scopus 로고
    • Alopecia areata and affected skin CRH receptor upregulation induced by acute emotional stress
    • DOI 10.1159/000051732
    • Katsarou-Katsari A, Singh LK, Theoharides TC,. Alopecia areata and affected skin CRH receptor upregulation induced by acute emotional stress. Dermatology 2001: 203: 157-161. (Pubitemid 34701577)
    • (2001) Dermatology , vol.203 , Issue.2 , pp. 157-161
    • Katsarou-Katsari, A.1    Singh, L.K.2    Theoharides, T.C.3
  • 94
    • 0142185337 scopus 로고    scopus 로고
    • Estrogen receptor β in the paraventricular nucleus of hypothalamus regulates the neuroendocrine response to stress and is regulated by corticosterone
    • DOI 10.1016/S0306-4522(03)00561-X
    • Isgor C, Cecchi M, Kabbaj M, Akil H, Watson SJ,. Estrogen receptor beta in the paraventricular nucleus of hypothalamus regulates the neuroendocrine response to stress and is regulated by corticosterone. Neuroscience 2003: 121: 837-845. (Pubitemid 37324582)
    • (2003) Neuroscience , vol.121 , Issue.4 , pp. 837-845
    • Isgor, C.1    Cecchi, M.2    Kabbaj, M.3    Akil, H.4    Watson, S.J.5
  • 95
    • 77949539634 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone stimulates the in situ generation of mast cells from precursors in the human hair follicle mesenchyme
    • Ito N, Sugawara K, Bodo E, et al,. Corticotropin-releasing hormone stimulates the in situ generation of mast cells from precursors in the human hair follicle mesenchyme. J Invest Dermatol 2010: 130: 995-1004.
    • (2010) J Invest Dermatol , vol.130 , pp. 995-1004
    • Ito, N.1    Sugawara, K.2    Bodo, E.3
  • 96
    • 77958504055 scopus 로고    scopus 로고
    • Hair follicle is a target of stress hormone and autoimmune reactions
    • Ito T,. Hair follicle is a target of stress hormone and autoimmune reactions. J Dermatol Sci 2010: 60: 67-73.
    • (2010) J Dermatol Sci , vol.60 , pp. 67-73
    • Ito, T.1
  • 97
    • 0035125256 scopus 로고    scopus 로고
    • Expression of neuropeptide-degrading enzymes in alopecia areata: An immunohistochemical study
    • DOI 10.1046/j.1365-2133.2001.03951.x
    • Toyoda M, Makino T, Kagoura M, Morohashi M,. Expression of neuropeptide-degrading enzymes in alopecia areata: an immunohistochemical study. Br J Dermatol 2001: 144: 46-54. (Pubitemid 32154592)
    • (2001) British Journal of Dermatology , vol.144 , Issue.1 , pp. 46-54
    • Toyoda, M.1    Makino, T.2    Kagoura, M.3    Morohashi, M.4
  • 98
    • 62349131850 scopus 로고    scopus 로고
    • Investigation of the inflammatory mechanisms in alopecia areata
    • Cetin ED, Savk E, Uslu M, Eskin M, Karul A,. Investigation of the inflammatory mechanisms in alopecia areata. Am J Dermatopathol 2009: 31: 53-60.
    • (2009) Am J Dermatopathol , vol.31 , pp. 53-60
    • Cetin, E.D.1    Savk, E.2    Uslu, M.3    Eskin, M.4    Karul, A.5
  • 100
    • 33646090862 scopus 로고    scopus 로고
    • The diagnosis and treatment of iron deficiency and its potential relationship to hair loss
    • Trost LB, Bergfeld WF, Calogeras E,. The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. J Am Acad Dermatol 2006: 54: 824-844.
    • (2006) J Am Acad Dermatol , vol.54 , pp. 824-844
    • Trost, L.B.1    Bergfeld, W.F.2    Calogeras, E.3
  • 101
    • 0028962986 scopus 로고
    • Iron status of patients with alopecia areata
    • Boffa MJ, Wood P, Griffiths CE,. Iron status of patients with alopecia areata. Br J Dermatol 1995: 132: 662-664.
    • (1995) Br J Dermatol , vol.132 , pp. 662-664
    • Boffa, M.J.1    Wood, P.2    Griffiths, C.E.3
  • 102
    • 0028356601 scopus 로고
    • A study of the tissue iron status of patients with alopecia areata [7]
    • White MI, Currie J, Williams MP,. A study of the tissue iron status of patients with alopecia areata. Br J Dermatol 1994: 130: 261-263. (Pubitemid 24204632)
    • (1994) British Journal of Dermatology , vol.130 , Issue.2 , pp. 261-263
    • White, M.I.1    Currie, J.2    Williams, M.P.3
  • 103
    • 77951900264 scopus 로고    scopus 로고
    • Serum vitamin B12, folate, ferritin, and iron levels in Turkish patients with alopecia areata
    • Gonul M, Cakmak SK, Soylu S, Kilic A, Gul U,. Serum vitamin B12, folate, ferritin, and iron levels in Turkish patients with alopecia areata. Indian J Dermatol Venereol Leprol 2009: 75: 552.
    • (2009) Indian J Dermatol Venereol Leprol , vol.75 , pp. 552
    • Gonul, M.1    Cakmak, S.K.2    Soylu, S.3    Kilic, A.4    Gul, U.5
  • 104
    • 0028944947 scopus 로고
    • Antioxidant and antipromotional effects of the soybean isoflavone genistein
    • Wei H, Bowen R, Cai Q, Barnes S, Wang Y,. Antioxidant and antipromotional effects of the soybean isoflavone genistein. Proc Soc Exp Biol Med 1995: 208: 124-130.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 124-130
    • Wei, H.1    Bowen, R.2    Cai, Q.3    Barnes, S.4    Wang, Y.5
  • 105
    • 0041392200 scopus 로고
    • Alopecia areata; Prevalence in Japanese and prognosis after reassurance
    • Arnold HL Jr,. Alopecia areata; prevalence in Japanese and prognosis after reassurance. AMA Arch Derm Syphilol 1952: 66: 191-196.
    • (1952) AMA Arch Derm Syphilol , vol.66 , pp. 191-196
    • Arnold, Jr.H.L.1
  • 107
    • 0029792494 scopus 로고    scopus 로고
    • No correlation between cytomegalovirus and alopecia areata
    • Tosti A, La Placa M, Placucci F, et al,. No correlation between cytomegalovirus and alopecia areata. J Invest Dermatol 1996: 107: 443.
    • (1996) J Invest Dermatol , vol.107 , pp. 443
    • Tosti, A.1    La Placa, M.2    Placucci, F.3
  • 111
    • 77954223152 scopus 로고    scopus 로고
    • Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
    • Petukhova L, Duvic M, Hordinsky M, et al,. Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature 2010: 466: 113-117.
    • (2010) Nature , vol.466 , pp. 113-117
    • Petukhova, L.1    Duvic, M.2    Hordinsky, M.3
  • 113
    • 62449096863 scopus 로고    scopus 로고
    • Recombinant human hepatitis B vaccine initiating alopecia areata: Testing the hypothesis using the C3H/HeJ mouse model
    • Sundberg JP, Silva KA, Zhang W, et al,. Recombinant human hepatitis B vaccine initiating alopecia areata: testing the hypothesis using the C3H/HeJ mouse model. Vet Dermatol 2009: 20: 99-104.
    • (2009) Vet Dermatol , vol.20 , pp. 99-104
    • Sundberg, J.P.1    Silva, K.A.2    Zhang, W.3
  • 114
    • 47549119708 scopus 로고    scopus 로고
    • Etiology of cicatricial alopecias: A basic science point of view
    • DOI 10.1111/j.1529-8019.2008.00202.x
    • McElwee KJ,. Etiology of cicatricial alopecias: a basic science point of view. Dermatol Ther 2008: 21: 212-220. (Pubitemid 352009066)
    • (2008) Dermatologic Therapy , vol.21 , Issue.4 , pp. 212-220
    • McElwee, K.J.1
  • 115
    • 38949192667 scopus 로고    scopus 로고
    • Diagnosis and management of primary cicatricial alopecia: Part i
    • Otberg N, Wu WY, McElwee KJ, Shapiro J,. Diagnosis and management of primary cicatricial alopecia: part I. Skinmed 2008: 7: 19-26.
    • (2008) Skinmed , vol.7 , pp. 19-26
    • Otberg, N.1    Wu, W.Y.2    McElwee, K.J.3    Shapiro, J.4
  • 116
    • 44049099812 scopus 로고    scopus 로고
    • Diagnosis and management of primary cicatricial alopecia: Part II
    • Wu WY, Otberg N, McElwee KJ, Shapiro J,. Diagnosis and management of primary cicatricial alopecia: part II. Skinmed 2008: 7: 78-83.
    • (2008) Skinmed , vol.7 , pp. 78-83
    • Wu, W.Y.1    Otberg, N.2    McElwee, K.J.3    Shapiro, J.4
  • 117
    • 51949118037 scopus 로고    scopus 로고
    • The C3H/HeJ mouse and DEBR rat models for alopecia areata: Review of preclinical drug screening approaches and results
    • Sun J, Silva KA, McElwee KJ, King LE Jr, Sundberg JP,. The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results. Exp Dermatol 2008: 17: 793-805.
    • (2008) Exp Dermatol , vol.17 , pp. 793-805
    • Sun, J.1    Silva, K.A.2    McElwee, K.J.3    King Jr., L.E.4    Sundberg, J.P.5
  • 119
    • 0019478717 scopus 로고
    • Immunofluorescence findings in rapid whitening of scalp hair
    • DOI 10.1001/archderm.117.9.576
    • Guin JD, Kumar V, Petersen BH,. Immunofluorescence findings in rapid whitening of scalp hair. Arch Dermatol 1981: 117: 576-578. (Pubitemid 11049433)
    • (1981) Archives of Dermatology , vol.117 , Issue.9 , pp. 576-578
    • Guin, J.D.1    Kumar, V.2    Petersen, B.H.3
  • 120
    • 0020001325 scopus 로고
    • The graying phenomenon. An unusal manifestation of alopecia areata
    • De Villez RL, Buchanan JM,. The graying phenomenon: an unusual manifestation of alopecia areata. Int J Dermatol 1982: 21: 344-346. (Pubitemid 12039895)
    • (1982) International Journal of Dermatology , vol.21 , Issue.6 , pp. 344-346
    • De Villez, R.L.1    Buchanan, J.M.2
  • 122
    • 16644388783 scopus 로고    scopus 로고
    • Alopecia areata investigational assessment guidelines - Part II. National Alopecia Areata Foundation
    • Olsen EA, Hordinsky MK, Price VH, et al,. Alopecia areata investigational assessment guidelines-Part II. National Alopecia Areata Foundation. J Am Acad Dermatol 2004: 51: 440-447.
    • (2004) J Am Acad Dermatol , vol.51 , pp. 440-447
    • Olsen, E.A.1    Hordinsky, M.K.2    Price, V.H.3
  • 123
    • 77953970947 scopus 로고    scopus 로고
    • Type 1 interferon signature in the scalp lesions of alopecia areata
    • Ghoreishi M, Martinka M, Dutz JP,. Type 1 interferon signature in the scalp lesions of alopecia areata. Br J Dermatol 2010: 163: 57-62.
    • (2010) Br J Dermatol , vol.163 , pp. 57-62
    • Ghoreishi, M.1    Martinka, M.2    Dutz, J.P.3
  • 126
    • 33644815171 scopus 로고    scopus 로고
    • Reduced expression of interleukin-2 decreases the frequency of alopecia areata onset in C3H/HeJ mice
    • Freyschmidt-Paul P, McElwee KJ, Hoffmann R, et al,. Reduced expression of interleukin-2 decreases the frequency of alopecia areata onset in C3H/HeJ mice. J Invest Dermatol 2005: 125: 945-951.
    • (2005) J Invest Dermatol , vol.125 , pp. 945-951
    • Freyschmidt-Paul, P.1    McElwee, K.J.2    Hoffmann, R.3


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