Expression of neuropeptide-degrading enzymes in alopecia areata: An immunohistochemical study

British Journal of Dermatology

Volumn 144, Issue 1, 2001, Pages 46-54

  Toyoda, M ^a   Makino, T ^a   Kagoura, M ^a   Morohashi, M ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Alopecia areata; Angiotensin converting enzyme; Immunohistochemistry; Mast cells; Neutral endopeptidase; Substance P

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; MEMBRANE METALLOENDOPEPTIDASE; NEUROPEPTIDE; SUBSTANCE P;

ADULT; ALOPECIA AREATA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HAIR FOLLICLE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MALE; MAST CELL DEGRANULATION; MENTAL STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCALP; SKIN BIOPSY;

ADULT; ALOPECIA AREATA; E-SELECTIN; ENDOTHELIUM, VASCULAR; FEMALE; HAIR FOLLICLE; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MAST CELLS; NEPRILYSIN; NERVE FIBERS; NEUROPEPTIDES; PEPTIDYL-DIPEPTIDASE A; SCALP; SUBSTANCE P;

EID: 0035125256     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2001.03951.x     Document Type: Article

References (35)

1. Alopecia areata: A clinical study
2. Alopecia areata - A psychiatric survey
3. Alopecia areata: An evaluation of 736 patients
4. Emotionally triggered disease in a dermatologic practice
5. Alopecia areata and increased prevalence of psychiatric disorders
6. Stress and alopecia areata: A psychodermatologic study
7. Neurogenic inflammation
8. Neuropeptides and skin inflammation
9. Stress, symmetry and psoriasis: Possible role of neuropeptides
10. Substance P levels are decreased in lesional skin of atopic dermatitis
11. Substance P is diminished and vasoactive intestinal peptide is augmented in psoriatic lesions and these peptides exert disparate effects on the proliferation of cultured human keratinocytes
12. Quantification of cutaneous sensory nerves and their substance P content in psoriasis
13. The alterations of cutaneous innervation and neuropeptide expression by cyclosporin A treatment in atopic dermatitis: An immunohistochemical study
14. Acute immobilization stress triggers skin mast cell degranulation via corticotropin releasing hormone, neurotensin, and substance P, a link to neurogenic skin disorders
15. Neuropeptides in the skin: Interactions between the neuroendocrine and the skin immune system
16. Substance P induces the expression of an endothelial-leukocyte adhesion molecule by microvascular endothelium
17. Possible involvement of neuropeptidergic sensory nerves in alopecia areata
18. Innervation and vasculature of the normal human and alopecia areata (AA) hair follicle: An immunohistochemical, laser scanning confocal microscopic study
19. Morphological alteration of epidermal melanocytes in photoageing: An ultrastructural and cytomorphometrical study
20. Neutral metalloendopeptidase in human lung tissue and cultured cells
21. Angiotensin-converting enzyme: Characteristics in human fibroblasts
22. Effects of smokeless tobacco on chemically transformed hamster oral keratinocytes: Role of angiotensin I-converting enzyme
23. Neutral endopeptidase expression and distribution in human skin and wounds
24. Peribulbar innervation and substance P expression following nonpermanent injury to the human scalp hair follicle
25. Morphological assessment of the effects of cyclosporin A on mast cell-nerve relationship in atopic dermatitis
26. Angiotensin-converting enzyme: Vascular endothelial localization
27. Inhibitors of neprilysin: Design, pharmacological and clinical applications
28. Effects of angiotensin converting enzyme and neutral endopeptidase inhibitors: Influence of bradykinin
29. Hair growth induction by substance P
30. Substance P selectively activates TNF-alpha gene expression in murine mast cells
31. Interactions between neutral endopeptidase (EC 3.4.24.1.1) and the substance P (NK1) receptor expressed in mammalian cells
32. Can alopecia areata be triggered by emotional stress? An uncontrolled evaluation of 178 patients with extensive hair loss
33. Alopecia areata. A follow-up investigation of outpatient material
34. Life events and alopecia areata
35. Alopecia areata: A clinical study