Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity

Annals of the New York Academy of Sciences

Volumn 966, Issue , 2002, Pages 290-303

  Elenkov, Ilia J ^a,b   Chrousos, George P ^b  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Autoimmunity; Catecholamines; Glucocorticoids; Inflammation; Interleukin 10, Th1 cells, Th2 cells, rheumatoid arthritis; Interleukin 12; Multiple sclerosis; Stress

Indexed keywords

CYTOKINE; GLUCOCORTICOID; INTERLEUKIN 10; INTERLEUKIN 12; TUMOR NECROSIS FACTOR ALPHA;

AUTOIMMUNITY; CATECHOLAMINE RELEASE; CONFERENCE PAPER; DISEASE ACTIVITY; HORMONAL REGULATION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOCOMPETENT CELL; MULTIPLE SCLEROSIS; NEGATIVE FEEDBACK; NONHUMAN; RHEUMATOID ARTHRITIS; STRESS; TISSUE INJURY;

EID: 0036307544     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04229.x     Document Type: Conference Paper

References (74)

1. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
2. The sympathetic nerve - An integrative interface between two supersystems: The brain and the immune system
3. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones
4. Differential dependence of ACTH secretion induced by various cytokines on the integrity of the paraventricular nucleus
5. The expanding universe of T-cell subsets: Th1, Th2 and more
6. The instructive role of innate immunity in the acquired immune response
7. Stress hormones, Th1/Th2 patterns, Pro/Antiinflammatory cytokines and susceptibility to disease
8. Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
9. Control of cachectin (tumor necrosis factor) synthesis: Mechanisms of endotoxin resistance
10. Glucocorticoid therapy for immune-mediated diseases: Basic and clinical correlates
11. Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: Clinical implications
12. 4+ lymphocytes
13. 4+ lymphocytes by inhibiting IL-12 production
14. Prostaglandin E2 and dexamethasone inhibit IL-12 receptor expression and IL-12 responsiveness
15. Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia - A clinical research center study
16. 4+ T cells in vitro
17. Corticosteroids increase blood interleukin-10 levels during cardiopulmonary bypass in men
18. Glucocorticoids increase IL-10 expression in multiple sclerosis patients with acute relapse
19. Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12
20. Stimulation of beta-adrenoceptors inhibits endotoxin-induced IL-12 production in normal and IL-10 deficient mice
21. Differential expression of the beta2-adrenergic receptor by Th1 and Th2 clones: Implications for cytokine production and B cell help
22. Beta-adrenoceptor-mediated inhibition of IFN-gamma, IL-3, and GM-CSF mRNA accumulation in activated human T lymphocytes is solely mediated by the beta2-adrenoceptor subtype
23. Differential effect of selective block of alpha 2-adrenoreceptors on plasma levels of tumour necrosis factor-alpha, interleukin-6 and corticosterone induced by bacterial lipopolysaccharide in mice
24. Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury
25. Modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by selective alpha- and beta-adrenergic drugs in mice
26. An immunopharmacological analysis of adrenaline-induced suppression of human natural killer cell cytotoxicity
27. Stress-induced immune suppression: Role of brain corticotropin releasing hormone and autonomic nervous system mechanisms
28. Differential regulation of transforming growth factor beta-1 gene expression by glucocorticoids in human T and glial cells
29. Stimulation of α-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor
30. Hemorrhage increases cytokine expression in lung mononuclear cells in mice: Involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression
31. Loss of response to beta-adrenoceptor agonists during the maturation of human monocytes to macrophages in vitro
32. Dose- and time-dependent activation of rat alveolar macrophages by glucocorticoids
33. Effects of stress on alveolar macrophages: A role for the sympathetic nervous system
34. Beta 2-Adrenergic activation enhances interleukin-8 production by human monocytes
35. Increased interleukin-8 release by beta-adrenoceptor activation in human transformed bronchial epithelial cells
36. Substance P and calcitonin gene-related peptide: Effects on mast cells and in human skin
37. Interaction of neuropeptides with human mast cells
38. Stress-induced intracranial mast cell degranulation: A corticotropin-releasing hormone-mediated effect
39. Corticotropin-releasing hormone induces skin mast cell degranulation and increased vascular permeability, a possible explanation for its proinflammatory effects
40. Autocrine or paracrine inflammatory actions of corticotropin-releasing hormone in vivo
41. Enhancing effect of corticotropin-releasing neurohormone on the production of interleukin-1 and interleukin-2
42. Stimulation of interleukin-6 production by corticotropin-releasing factor
43. Effect of neuropeptides on production of inflammatory cytokines by human monocytes
44. Substance P-induced IL-12 production by murine macrophages
45. Substance P C-terminal octapeptide analogues augment tumor necrosis factor-alpha release by human blood monocytes and macrophages
46. Involvement of the hypothalamic-pituitary-adrenal/gonadal axis and the peripheral nervous system in rheumatoid arthritis: Viewpoint based on a systemic pathogenetic role
47. An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease
48. Neuroendocrine-immune system interactions and autoimmunity
49. Hormonal regulation of tumor necrosis factor-alpha, interleukin-12 and interleukin-10 production by activated macrophages. A disease-modifying mechanism in rheumatoid arthritis and systemic lupus erythematosus?
50. Sympathetic skin responses are decreased and lymphocyte beta-adrenergic receptors are increased in progressive multiple sclerosis
51. Blood lymphocyte beta-adrenergic receptors in multiple sclerosis
52. Increased high affinity beta-adrenergic receptor densities and cyclic AMP responses of CD8 cells in multiple sclerosis
53. Changes in lymphocyte β-adrenergic receptor density and noradrenaline content of the spleen are early indicators of immune reactivity in acute experimental allergic encephalomyelitis in the Lewis rat
54. Immunoregulation in rapidly progressive multiple sclerosis
55. The beta-adrenergic agonist isoproterenol suppresses experimental allergic encephalomyelitis in Lewis rats
56. Beta-adrenergic agonists suppress chronic/relapsing experimental allergic encephalomyelitis (CREAE) in Lewis rats
57. Application of 6-hydroxydopamine into the fatpads surrounding the draining lymph nodes exacerbates adjuvant-induced arthritis
58. Noradrenergic and peptidergic innervation of secondary lymphoid organs: Role in experimental rheumatoid arthritis
59. The beta2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: Mechanisms of action
60. Diminished autonomic nervous system responsiveness in rheumatoid arthritis of recent onset
61. The loss of sympathetic nerve fibers in the synovial tissue of patients with rheumatoid arthritis is accompanied by increased norepinephrine release from synovial macrophages
62. Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis
63. The effects of pregnancy on autoimmune diseases
64. The effects of pregnancy on autoimmune diseases
65. Rate of pregnancy-related relapse in multiple sclerosis. Pregnancy in Multiple Sclerosis Group
66. Identification of four new quantitative trait loci regulating arthritis severity and one new quantitative trait locus regulating autoantibody production in rats with collagen-induced arthritis
67. Systemic lupus erythematosus flares during pregnancy
68. Hopkins Lupus Pregnancy Center: 1987 to 1996
69. Frequency of lupus flare in pregnancy. The Hopkins Lupus Pregnancy Center experience
70. Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy
71. Interleukin-10 messenger ribonucleic acid in human placenta: Implications of a role for interleukin-10 in fetal allograft protection
72. Amniotic fluid interleukin-10 concentrations increase through pregnancy and are elevated in patients with preterm labor associated with intrauterine infection
73. IL-12, TNF-alpha, and hormonal changes during late pregnancy and early postpartum: Implications for autoimmune disease activity during these times
74. Does differential neuroendocrine control of cytokine production govern the expression of autoimmune diseases in pregnancy and the postpartum period?