Clusters of perifollicular macrophages in normal murine skin: Physiological degeneration of selected hair follicles by programmed organ deletion

Journal of Histochemistry and Cytochemistry

Volumn 46, Issue 3, 1998, Pages 361-370

  Eichmüller, Stefan ^a   Van Der Veen, Carina ^a   Moll, Ingrid ^b   Hermes, Barbara ^a   Hofmann, Udo ^a   Müller Röver, Sven ^a   Paus, Ralf ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Alopecia; Apoptosis; Hair cycle; ICAM 1; Inflammation; Lymphocyte; Macrophage; MHC Class II

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BASEMENT MEMBRANE; CONTROLLED STUDY; FEMALE; HAIR FOLLICLE; IMMUNOPHENOTYPING; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; KERATINOCYTE; MACROPHAGE MIGRATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN INFLAMMATION;

ANIMALIA; MURINAE; MYCOBACTERIUM AVIUM COMPLEX (MAC);

EID: 0031883889     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549804600310     Document Type: Article

References (39)

1. Argyris TS (1967) Hair growth induced by damage. Adv Biol Skin 9:339-345
2. Bos JD, ed. (1997) The Skin Immune System. Boca Raton, FL, CRC Press
3. Cotsarelis G, Sun TT, Lavker RM (1990) Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61:1329-1337
4. Eichmüller S, Paus R, Behne E, Czarnetzki BM, Hofmann U (1994) Hair cycle-associated changes of the skin immune status: MHC class II- and NLDC145-immunoreactivity in murine skin. J Invest Dermatol 103:446a
5. Eichmüller S, Stevenson PA, Paus R (1996) A new method for double immunolabelling with primary antibodies from identical species. J Immunol Methods 190:255-265
6. Eichmüller S, van der Veen C, Moll I, Hermes B, Hofmann U, Müller-Röver S, Paus R (1997) Perifollicular macrophage clusters in normal murine skin as indicators of physiological, programmed hair follicle degeneration? Arch Dermatol Res 289 (suppl):A14
7. Elston DM, Bergfield WF (1994) Cicatricial alopecia (and other causes of permanent alopecia). In Olsen EA, ed. Disorders of Hair Growth. New York, McGraw-Hill, 285-314
8. Gilbert SF (1994) Developmental Biology. 4th ed. Sunderland, MA, Sinauer Associates
9. Hermes B, Paus R (in press) Vernarbende Alopezie: Anmerkungen zur Klassifikation, Differentialdiagnose, und Pathobiologie. Hautarzt
10. Hofmann U, Tokura Y, Nishijima T, Takigawa M, Paus R (1996) Hair cycle dependent changes in skin immune functions: Anagen associated depression of sensitization for contact hypersensitivity in mice. J Invest Dermatol 106:589-604
11. Jaworsky C, Kligman AM, Murphy GF (1992) Characterization of inflammatory infiltrates in male pattern alopecia: implications for pathogenesis. Br J Dermatol 127:239-246
12. Lattand A, Johnson J (1975) Male pattern alopecia: a histopathological and histochemical study. J Cutan Pathol 2:58-70
13. Lavker RM, Miller S, Wilson C, Cotsarelis G, Wei Z-G, Yang J-S, Sun T-T (1993) Hair follicle stem cells: their location, role in hair cycle, and involvement in skin tumor formation. J Invest Dermatol 101(suppl):16S-26S
14. Lindner G, Botchkarev VA, Botchkareva NV, Gao L, van der Veen C, Paus R (1997) Analysis of apoptosis during hair follicle regression (catagen). Am J Pathol, in press
15. Mann SJ (1969) The tylotrich hair follicle as a marker system in the skin. In Montagna W, Dobson RL, eds. Hair Growth. Oxford, Pergamon Press, 399-415
16. Maurer M, Foitzik K, Eichmüller S, Handjiski B, Czarnetzki BM, Paus R (1995) IL-1 receptor, TGF-β receptor, and alkaline phosphatase activity are markers of early murine hair follicle development. J Invest Dermatol 105:494a
17. Moll I, Paus R, Moll R (1996) Merkel cells in mouse skin: intermediate filament pattern, localization, and hair cycle-dependent density. J Invest Dermatol 106:281-286
18. Müller WF (1997) Developmental Biology. New York, Springer-Verlag
19. Murphy GF (1995) Dermatopathology. Philadelphia, WB Saunders
20. Murphy GF, Lavker RM, Whitaker D, Korngold R (1991) Cytotoxic folliculitis in GvHD. Evidence of follicular stem cell injury and recovery. J Cutan Pathol 18:309-314
21. Olsen EA, ed. (1994) Disorders of Hair Growth: Diagnosis and Treatment. New York, McGraw-Hill
22. Parakkal PF (1969) Role of macrophages in collagen resorption during hair growth cycle. J Ultrastruct Res 29:210-217
23. Paus R (1996) Control of the hair cycle and hair diseases as cycling disorders. Curr Opin Dermatol 3:248-258
24. Paus R (1997) Immunology of the hair follicle. In Bos JD, ed. The Skin Immune System. Boca Raton, FL, CRC Press, 337-398
25. Paus R, Eichmüller S, Hofmann U, Czarnetzki BM (1994a) Expression of classical and non-classical MHC class I antigens in murine hair follicles. Br J Dermatol 131:177-183
26. Paus R, Handjiski B, Czarnetzki BM, Eichmüller S (1994b) A murine model for inducing and manipulating hair follicle regression (catagen): effects of dexamethasone and cyclosporin A. J Invest Dermatol 103:143-147
27. Paus R, Hofmann U, Eichmüller S, Czarnetzki BM (1994c) Distribution and changing density of gamma-delta T cells in murine skin during the induced hair cycle. Br J Dermatol 130:281-289
28. Paus R, Krejci-Papa N, Li L, Czarnetzki BM, Hoffman RM (1994d) Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages. J Dermatol Sci 7:202-209
29. Paus R, Stenn KS, Link RE (1989) The induction of anagen hair growth in telogen mouse skin by cyclosporin A administration. Lab Invest 60:365-369
30. Romeis B (1989) Mikroskopische Technik. 17th ed. München, Urban & Schwarzenberg
31. Rook A, Dawber R, eds. (1991) Diseases of the Hair and Scalp. 2nd ed. London, Blackwell Scientific
32. Sachs L (1992) Angewandte Statistik. 4th ed. Berlin, Springer-Verlag
33. Stenn KS, Combates NJ, Eilertsen KJ, Gordon JS, Pardinas JR, Parimo S, Prouty SM (1996) Hair follicle growth controls. Dermatol Clin 14:543-558
34. Sundberg JP (1994) Handbook of Mouse Mutations with Skin and Hair Abnormalities. Boca Raton, FL, CRC Press
35. Templeton SF, Solomon AR (1994) Scarring alopecia: a classification based on microscopic criteria. J Cutan Pathol 21:97-109
36. Vlassara H, Brownlee M, Manogue KR, Dinarello CA, Pasagian A (1988) Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling. Science 240:1546-1548
37. Weedon D, Strutton G (1981) Apoptosis as the mechanism of the involution of hair follicles in catagen transformation. Acta Dermatol Venereol 61:335-339
38. Westgate GE, Craggs RI, Gibson WT (1991) Changes in the histology and distribution of immune cell types during the hair growth cycle in hairless rat skin. Ann NY Acad Sci 642:493-495
39. Zhang JG, Oliver RF (1994) Immunohistological study of the development of the cellular infiltrate in the pelage follicles of the DEBR model for alopecia areata. Br J Dermatol 130:405-414