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Volumn 62, Issue 2, 2010, Pages 177-188

Alopecia areata update. Part I. Clinical picture, histopathology, and pathogenesis

Author keywords

alopecia areata; alopecia totalis; alopecia universalis; nonscarring alopecia; pathogenesis; pathology

Indexed keywords

ALOPECIA AREATA; AUTOIMMUNITY; DEMOGRAPHY; DIAGNOSTIC ERROR; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; ENVIRONMENTAL IMPACT; EPIDERMIS; ETHNICITY; GENETIC SUSCEPTIBILITY; GROUPS BY AGE; HAIR FOLLICLE; HAIR GROWTH; HAIR LOSS; HISTOPATHOLOGY; HUMAN; HYPOTHESIS; LEARNING; LYMPHOCYTIC INFILTRATION; MORBIDITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SEX RATIO; THYROIDITIS; TINEA CAPITIS; TREATMENT RESPONSE; TRICHOTILLOMANIA;

EID: 73649148718     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2009.10.032     Document Type: Review
Times cited : (425)

References (104)
  • 1
    • 0030027082 scopus 로고    scopus 로고
    • Profile of alopecia areata in Northern India
    • Sharma V.K., Dawn G., and Kumar B. Profile of alopecia areata in Northern India. Int J Dermatol 35 (1996) 22-27
    • (1996) Int J Dermatol , vol.35 , pp. 22-27
    • Sharma, V.K.1    Dawn, G.2    Kumar, B.3
  • 2
    • 0036859489 scopus 로고    scopus 로고
    • The pattern and profile of alopecia areata in Singapore-a study of 219 Asians
    • Tan E., Tay Y.K., Goh C.L., and Chin Giam Y. The pattern and profile of alopecia areata in Singapore-a study of 219 Asians. Int J Dermatol 41 (2002) 748-753
    • (2002) Int J Dermatol , vol.41 , pp. 748-753
    • Tan, E.1    Tay, Y.K.2    Goh, C.L.3    Chin Giam, Y.4
  • 3
    • 0026664103 scopus 로고
    • Prevalence of alopecia areata in the First National Health and Nutrition Examination Survey
    • Safavi K. Prevalence of alopecia areata in the First National Health and Nutrition Examination Survey. Arch Dermatol 128 (1992) 702
    • (1992) Arch Dermatol , vol.128 , pp. 702
    • Safavi, K.1
  • 8
    • 0036861512 scopus 로고    scopus 로고
    • Alopecia areata in children: a clinical profile
    • Nanda A., Al-Fouzan A.S., and Al-Hasawi F. Alopecia areata in children: a clinical profile. Pediatr Dermatol 19 (2002) 482-485
    • (2002) Pediatr Dermatol , vol.19 , pp. 482-485
    • Nanda, A.1    Al-Fouzan, A.S.2    Al-Hasawi, F.3
  • 9
    • 0025729312 scopus 로고
    • Alopecia areata: clinical aspects
    • Price V.H. Alopecia areata: clinical aspects. J Invest Dermatol 96 (1991) 68S
    • (1991) J Invest Dermatol , vol.96
    • Price, V.H.1
  • 10
    • 29244447893 scopus 로고    scopus 로고
    • Disorders of hair
    • Burns D.A., Breathnach S.M., Cox N., and Griffiths C.E. (Eds), Wiley-Blackwell, Oxford p. 63.1-63.120
    • de Berker D.A.R., Messenger A.G., and Sinclair R.D. Disorders of hair. In: Burns D.A., Breathnach S.M., Cox N., and Griffiths C.E. (Eds). Rook's textbook of dermatology. 7th ed Vol. 4 (2004), Wiley-Blackwell, Oxford p. 63.1-63.120
    • (2004) Rook's textbook of dermatology. 7th ed , vol.4
    • de Berker, D.A.R.1    Messenger, A.G.2    Sinclair, R.D.3
  • 12
    • 0032972111 scopus 로고    scopus 로고
    • Alopecia areata: diagnosis and management
    • Shapiro J., and Madani S. Alopecia areata: diagnosis and management. Int J Dermatol 38 suppl 1 (1999) 19-24
    • (1999) Int J Dermatol , vol.38 , Issue.SUPPL. 1 , pp. 19-24
    • Shapiro, J.1    Madani, S.2
  • 13
    • 0141595201 scopus 로고    scopus 로고
    • Therapy of alopecia areata: on the cusp and in the future
    • Price V.H. Therapy of alopecia areata: on the cusp and in the future. J Investig Dermatol Symp Proc 8 (2003) 207-211
    • (2003) J Investig Dermatol Symp Proc , vol.8 , pp. 207-211
    • Price, V.H.1
  • 14
    • 0036435812 scopus 로고    scopus 로고
    • Acute diffuse and total alopecia of the female scalp. A new subtype of diffuse alopecia areata that has a favorable prognosis
    • Sato-Kawamura M., Aiba S., and Tagami H. Acute diffuse and total alopecia of the female scalp. A new subtype of diffuse alopecia areata that has a favorable prognosis. Dermatology 205 (2002) 367-373
    • (2002) Dermatology , vol.205 , pp. 367-373
    • Sato-Kawamura, M.1    Aiba, S.2    Tagami, H.3
  • 15
    • 57649156392 scopus 로고    scopus 로고
    • Acute diffuse and total alopecia: a new subtype of alopecia areata with a favorable prognosis
    • Lew B.L., Shin M.K., and Sim W.Y. Acute diffuse and total alopecia: a new subtype of alopecia areata with a favorable prognosis. J Am Acad Dermatol 60 (2009) 85-93
    • (2009) J Am Acad Dermatol , vol.60 , pp. 85-93
    • Lew, B.L.1    Shin, M.K.2    Sim, W.Y.3
  • 17
    • 33749684977 scopus 로고    scopus 로고
    • Videodermoscopy in the evaluation of hair and scalp disorders
    • Ross E.K., Vincenzi C., and Tosti A. Videodermoscopy in the evaluation of hair and scalp disorders. J Am Acad Dermatol 55 (2006) 799-806
    • (2006) J Am Acad Dermatol , vol.55 , pp. 799-806
    • Ross, E.K.1    Vincenzi, C.2    Tosti, A.3
  • 19
    • 0025605293 scopus 로고
    • Ultrastructural study of exclamation-mark hair shafts in alopecia areata
    • Tobin D.J., Fenton D.A., and Kendall M.D. Ultrastructural study of exclamation-mark hair shafts in alopecia areata. J Cutan Pathol 17 (1990) 348-354
    • (1990) J Cutan Pathol , vol.17 , pp. 348-354
    • Tobin, D.J.1    Fenton, D.A.2    Kendall, M.D.3
  • 20
    • 0036097067 scopus 로고    scopus 로고
    • Clinical and molecular diagnostic criteria of congenital atrichia with papular lesions
    • Zlotogorski A., Panteleyev A.A., Aita V.M., and Christiano A.M. Clinical and molecular diagnostic criteria of congenital atrichia with papular lesions. J Invest Dermatol 118 (2002) 887-890
    • (2002) J Invest Dermatol , vol.118 , pp. 887-890
    • Zlotogorski, A.1    Panteleyev, A.A.2    Aita, V.M.3    Christiano, A.M.4
  • 21
    • 33746932869 scopus 로고    scopus 로고
    • Alopecia areata: a long term follow-up study of 191 patients
    • Tosti A., Bellavista S., and Iorizzo M. Alopecia areata: a long term follow-up study of 191 patients. J Am Acad Dermatol 55 (2006) 438-441
    • (2006) J Am Acad Dermatol , vol.55 , pp. 438-441
    • Tosti, A.1    Bellavista, S.2    Iorizzo, M.3
  • 22
    • 0000937788 scopus 로고
    • A statistical study and consideration of endocrine influences
    • Walker S.A., and Rothman S. A statistical study and consideration of endocrine influences. J Invest Dermatol 14 (1950) 403-413
    • (1950) J Invest Dermatol , vol.14 , pp. 403-413
    • Walker, S.A.1    Rothman, S.2
  • 24
    • 58449131292 scopus 로고    scopus 로고
    • Nail changes in alopecia areata: frequency and clinical presentation
    • Kasumagic-Halilovic E., and Prohic A. Nail changes in alopecia areata: frequency and clinical presentation. J Eur Acad Dermatol Venereol 23 (2009) 240-241
    • (2009) J Eur Acad Dermatol Venereol , vol.23 , pp. 240-241
    • Kasumagic-Halilovic, E.1    Prohic, A.2
  • 25
    • 27744471407 scopus 로고    scopus 로고
    • Evaluation of the profile of alopecia areata and the prevalence of thyroid function test abnormalities and serum autoantibodies in Iranian patients
    • Seyrafi H., Akhiani M., Abbasi H., Mirpour S., and Gholamrezanezhad A. Evaluation of the profile of alopecia areata and the prevalence of thyroid function test abnormalities and serum autoantibodies in Iranian patients. BMC Dermatol 5 (2005) 11
    • (2005) BMC Dermatol , vol.5 , pp. 11
    • Seyrafi, H.1    Akhiani, M.2    Abbasi, H.3    Mirpour, S.4    Gholamrezanezhad, A.5
  • 26
    • 51949087626 scopus 로고    scopus 로고
    • Thyroid autoimmunity in patients with alopecia areata
    • Kasumagic-Halilovic E. Thyroid autoimmunity in patients with alopecia areata. Acta Dermatovenerol Croat 16 (2008) 123-125
    • (2008) Acta Dermatovenerol Croat , vol.16 , pp. 123-125
    • Kasumagic-Halilovic, E.1
  • 28
    • 33748894922 scopus 로고    scopus 로고
    • Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history
    • Goh C., Finkel M., Christos P.J., and Sinha A.A. Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history. J Eur Acad Dermatol Venereol 20 (2006) 1055-1060
    • (2006) J Eur Acad Dermatol Venereol , vol.20 , pp. 1055-1060
    • Goh, C.1    Finkel, M.2    Christos, P.J.3    Sinha, A.A.4
  • 29
    • 0028277331 scopus 로고
    • Increased risk for type I (insulin-dependent) diabetes in relatives of patients with alopecia areata (AA)
    • Wang S.J., Shohat T., Vadheim C., Shellow W., Edwards J., and Rotter J.I. Increased risk for type I (insulin-dependent) diabetes in relatives of patients with alopecia areata (AA). Am J Med Genet 51 (1994) 234-239
    • (1994) Am J Med Genet , vol.51 , pp. 234-239
    • Wang, S.J.1    Shohat, T.2    Vadheim, C.3    Shellow, W.4    Edwards, J.5    Rotter, J.I.6
  • 30
  • 33
    • 0022633471 scopus 로고
    • Alopecia areata: alterations in the hair growth cycle and correlation with the follicular pathology
    • Messenger A.G., Slater D.N., and Bleehen S.S. Alopecia areata: alterations in the hair growth cycle and correlation with the follicular pathology. Br J Dermatol 114 (1986) 337-347
    • (1986) Br J Dermatol , vol.114 , pp. 337-347
    • Messenger, A.G.1    Slater, D.N.2    Bleehen, S.S.3
  • 34
    • 84857822572 scopus 로고    scopus 로고
    • Diseases of cutaneous appendages
    • Weedon D. (Ed), Churchill Livingstone, London
    • Weedon D. Diseases of cutaneous appendages. In: Weedon D. (Ed). Weedon's skin pathology (2002), Churchill Livingstone, London
    • (2002) Weedon's skin pathology
    • Weedon, D.1
  • 35
    • 0030743458 scopus 로고    scopus 로고
    • Eosinophils in fibrous tracts and near hair bulbs: a helpful diagnostic feature of alopecia areata
    • Elston D.M., McCollough M.L., Bergfeld W.F., Liranzo M.O., and Heibel M. Eosinophils in fibrous tracts and near hair bulbs: a helpful diagnostic feature of alopecia areata. J Am Acad Dermatol 37 (1997) 101-106
    • (1997) J Am Acad Dermatol , vol.37 , pp. 101-106
    • Elston, D.M.1    McCollough, M.L.2    Bergfeld, W.F.3    Liranzo, M.O.4    Heibel, M.5
  • 36
    • 0033942638 scopus 로고    scopus 로고
    • Eosinophils in fibrous tracts and near hair bulbs: a helpful diagnostic feature of alopecia areata
    • El Darouti M., Marzouk S.A., and Sharawi E. Eosinophils in fibrous tracts and near hair bulbs: a helpful diagnostic feature of alopecia areata. J Am Acad Dermatol 42 (2000) 305-307
    • (2000) J Am Acad Dermatol , vol.42 , pp. 305-307
    • El Darouti, M.1    Marzouk, S.A.2    Sharawi, E.3
  • 38
    • 0346243854 scopus 로고    scopus 로고
    • Histopathologic features of alopecia areata: a new look
    • Whiting D.A. Histopathologic features of alopecia areata: a new look. Arch Dermatol 139 (2003) 1555-1559
    • (2003) Arch Dermatol , vol.139 , pp. 1555-1559
    • Whiting, D.A.1
  • 39
    • 0030764034 scopus 로고    scopus 로고
    • Morphological analysis of hair follicles in alopecia areata
    • Tobin D.J. Morphological analysis of hair follicles in alopecia areata. Microsc Res Tech 38 (1997) 443-451
    • (1997) Microsc Res Tech , vol.38 , pp. 443-451
    • Tobin, D.J.1
  • 41
    • 0025755884 scopus 로고
    • Cell degeneration in alopecia areata. An ultrastructural study
    • Tobin D.J., Fenton D.A., and Kendall M.D. Cell degeneration in alopecia areata. An ultrastructural study. Am J Dermatopathol 13 (1991) 248-256
    • (1991) Am J Dermatopathol , vol.13 , pp. 248-256
    • Tobin, D.J.1    Fenton, D.A.2    Kendall, M.D.3
  • 42
    • 0029008989 scopus 로고
    • Histopathology of alopecia areata in horizontal sections of scalp biopsies
    • 26S-7S
    • Whiting D.A. Histopathology of alopecia areata in horizontal sections of scalp biopsies. J Invest Dermatol 104 suppl 5 (1995) 26S-7S
    • (1995) J Invest Dermatol , vol.104 , Issue.SUPPL. 5
    • Whiting, D.A.1
  • 43
    • 84892357403 scopus 로고    scopus 로고
    • Biology of the hair follicle
    • Whiting D.A., Blume-Peytavi U., and Tosti A. (Eds), Springer, Berlin
    • Vogt A., McElwee K.J., and Blume-Peytavi U. Biology of the hair follicle. In: Whiting D.A., Blume-Peytavi U., and Tosti A. (Eds). Hair growth and disorders (2008), Springer, Berlin 1-22
    • (2008) Hair growth and disorders , pp. 1-22
    • Vogt, A.1    McElwee, K.J.2    Blume-Peytavi, U.3
  • 45
    • 84892335125 scopus 로고    scopus 로고
    • Alopecia areata
    • Whiting D.A., Blume-Peytavi U., and Tosti A. (Eds), Springer, Berlin
    • Freyschmidt-Paul P., McElwee K.J., and Hoffmann R. Alopecia areata. In: Whiting D.A., Blume-Peytavi U., and Tosti A. (Eds). Hair growth and disorders (2008), Springer, Berlin 311-332
    • (2008) Hair growth and disorders , pp. 311-332
    • Freyschmidt-Paul, P.1    McElwee, K.J.2    Hoffmann, R.3
  • 48
    • 0036634504 scopus 로고    scopus 로고
    • Epidemiology and genetics of alopecia areata
    • McDonagh A.J., and Tazi-Ahnini R. Epidemiology and genetics of alopecia areata. Clin Exp Dermatol 27 (2002) 405-409
    • (2002) Clin Exp Dermatol , vol.27 , pp. 405-409
    • McDonagh, A.J.1    Tazi-Ahnini, R.2
  • 49
    • 0027704964 scopus 로고
    • Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?
    • Paus R., Slominski A., and Czarnetzki B.M. Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?. Yale J Biol Med 66 (1993) 541-554
    • (1993) Yale J Biol Med , vol.66 , pp. 541-554
    • Paus, R.1    Slominski, A.2    Czarnetzki, B.M.3
  • 52
    • 73649136243 scopus 로고    scopus 로고
    • Alopecia areata: spontaneous rat model of alopecia areata
    • Chan L.S. (Ed), CRC Press, Boca Raton, FL
    • McElwee K.J. Alopecia areata: spontaneous rat model of alopecia areata. In: Chan L.S. (Ed). Animal models of human inflammatory skin diseases Vol V (2003), CRC Press, Boca Raton, FL 451-468
    • (2003) Animal models of human inflammatory skin diseases , vol.V , pp. 451-468
    • McElwee, K.J.1
  • 54
    • 0028277447 scopus 로고
    • Immunohistological study of the development of the cellular infiltrate in the pelage follicles of the DEBR model for alopecia areata
    • Zhang J.G., and Oliver R.F. Immunohistological study of the development of the cellular infiltrate in the pelage follicles of the DEBR model for alopecia areata. Br J Dermatol 130 (1994) 405-414
    • (1994) Br J Dermatol , vol.130 , pp. 405-414
    • Zhang, J.G.1    Oliver, R.F.2
  • 55
    • 0031738760 scopus 로고    scopus 로고
    • Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts
    • McElwee K.J., Boggess D., King Jr. L.E., and Sundberg J.P. Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts. J Invest Dermatol 111 (1998) 797-803
    • (1998) J Invest Dermatol , vol.111 , pp. 797-803
    • McElwee, K.J.1    Boggess, D.2    King Jr., L.E.3    Sundberg, J.P.4
  • 56
    • 1542706083 scopus 로고    scopus 로고
    • Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss
    • McElwee K.J., Silva K., Boggess D., Bechtold L., King Jr. L.E., and Sundberg J.P. Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss. Vet Pathol 40 (2003) 643-650
    • (2003) Vet Pathol , vol.40 , pp. 643-650
    • McElwee, K.J.1    Silva, K.2    Boggess, D.3    Bechtold, L.4    King Jr., L.E.5    Sundberg, J.P.6
  • 57
    • 0036038262 scopus 로고    scopus 로고
    • Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans
    • Carroll J.M., McElwee K.J., King Jr. L.E., Byrne M.C., and Sundberg J.P. Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans. J Invest Dermatol 119 (2002) 392-402
    • (2002) J Invest Dermatol , vol.119 , pp. 392-402
    • Carroll, J.M.1    McElwee, K.J.2    King Jr., L.E.3    Byrne, M.C.4    Sundberg, J.P.5
  • 58
    • 0033769951 scopus 로고    scopus 로고
    • Treatment with an anti-CD44v10-specific antibody inhibits the onset of alopecia areata in C3H/HeJ mice
    • Freyschmidt-Paul P., Seiter S., Zoller M., Konig A., Ziegler A., Sundberg J.P., et al. Treatment with an anti-CD44v10-specific antibody inhibits the onset of alopecia areata in C3H/HeJ mice. J Invest Dermatol 115 (2000) 653-657
    • (2000) J Invest Dermatol , vol.115 , pp. 653-657
    • Freyschmidt-Paul, P.1    Seiter, S.2    Zoller, M.3    Konig, A.4    Ziegler, A.5    Sundberg, J.P.6
  • 59
    • 0032912467 scopus 로고    scopus 로고
    • Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T cells
    • McElwee K.J., Spiers E.M., and Oliver R.F. Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T cells. Br J Dermatol 140 (1999) 432-437
    • (1999) Br J Dermatol , vol.140 , pp. 432-437
    • McElwee, K.J.1    Spiers, E.M.2    Oliver, R.F.3
  • 60
    • 0030003391 scopus 로고    scopus 로고
    • In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata
    • McElwee K.J., Spiers E.M., and Oliver R.F. In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata. Br J Dermatol 135 (1996) 211-217
    • (1996) Br J Dermatol , vol.135 , pp. 211-217
    • McElwee, K.J.1    Spiers, E.M.2    Oliver, R.F.3
  • 61
    • 18244400239 scopus 로고    scopus 로고
    • Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(-) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model
    • McElwee K.J., Freyschmidt-Paul P., Hoffmann R., Kissling S., Hummel S., Vitacolonna M., et al. Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(-) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model. J Invest Dermatol 124 (2005) 947-957
    • (2005) J Invest Dermatol , vol.124 , pp. 947-957
    • McElwee, K.J.1    Freyschmidt-Paul, P.2    Hoffmann, R.3    Kissling, S.4    Hummel, S.5    Vitacolonna, M.6
  • 62
    • 0036288663 scopus 로고    scopus 로고
    • Mediation of alopecia areata by cooperation between CD4+ and CD8+ T lymphocytes: transfer to human scalp explants on Prkdc(scid) mice
    • Gilhar A., Landau M., Assy B., Shalaginov R., Serafimovich S., and Kalish R.S. Mediation of alopecia areata by cooperation between CD4+ and CD8+ T lymphocytes: transfer to human scalp explants on Prkdc(scid) mice. Arch Dermatol 138 (2002) 916-922
    • (2002) Arch Dermatol , vol.138 , pp. 916-922
    • Gilhar, A.1    Landau, M.2    Assy, B.3    Shalaginov, R.4    Serafimovich, S.5    Kalish, R.S.6
  • 63
    • 51949118037 scopus 로고    scopus 로고
    • The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
    • Sun J., Silva K.A., McElwee K.J., King Jr. L.E., and Sundberg J.P. The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results. Exp Dermatol 17 (2008) 793-805
    • (2008) Exp Dermatol , vol.17 , pp. 793-805
    • Sun, J.1    Silva, K.A.2    McElwee, K.J.3    King Jr., L.E.4    Sundberg, J.P.5
  • 64
    • 34347389899 scopus 로고    scopus 로고
    • Anti-CD44-mediated blockade of leukocyte migration in skin-associated immune diseases
    • Zoller M., Gupta P., Marhaba R., Vitacolonna M., and Freyschmidt-Paul P. Anti-CD44-mediated blockade of leukocyte migration in skin-associated immune diseases. J Leukoc Biol 82 (2007) 57-71
    • (2007) J Leukoc Biol , vol.82 , pp. 57-71
    • Zoller, M.1    Gupta, P.2    Marhaba, R.3    Vitacolonna, M.4    Freyschmidt-Paul, P.5
  • 65
    • 38449108094 scopus 로고    scopus 로고
    • The importance of myeloid-derived suppressor cells in the regulation of autoimmune effector cells by a chronic contact eczema
    • Marhaba R., Vitacolonna M., Hildebrand D., Baniyash M., Freyschmidt-Paul P., and Zoller M. The importance of myeloid-derived suppressor cells in the regulation of autoimmune effector cells by a chronic contact eczema. J Immunol 179 (2007) 5071-5081
    • (2007) J Immunol , vol.179 , pp. 5071-5081
    • Marhaba, R.1    Vitacolonna, M.2    Hildebrand, D.3    Baniyash, M.4    Freyschmidt-Paul, P.5    Zoller, M.6
  • 66
    • 0018793692 scopus 로고
    • Synchronous alopecia areata in two siblings: a possible viral aetiology
    • Stankler L. Synchronous alopecia areata in two siblings: a possible viral aetiology. Lancet 1 (1979) 1303-1304
    • (1979) Lancet , vol.1 , pp. 1303-1304
    • Stankler, L.1
  • 68
  • 69
    • 0036092821 scopus 로고    scopus 로고
    • Antioxidant enzymes and lipid peroxidation in the scalp of patients with alopecia areata
    • Akar A., Arca E., Erbil H., Akay C., Sayal A., and Gur A.R. Antioxidant enzymes and lipid peroxidation in the scalp of patients with alopecia areata. J Dermatol Sci 29 (2002) 85-90
    • (2002) J Dermatol Sci , vol.29 , pp. 85-90
    • Akar, A.1    Arca, E.2    Erbil, H.3    Akay, C.4    Sayal, A.5    Gur, A.R.6
  • 70
    • 3242728308 scopus 로고    scopus 로고
    • Adult-onset alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model
    • Sundberg J.P., Silva K.A., Li R., Cox G.A., and King Jr. L.E. Adult-onset alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model. J Invest Dermatol 123 (2004) 294-297
    • (2004) J Invest Dermatol , vol.123 , pp. 294-297
    • Sundberg, J.P.1    Silva, K.A.2    Li, R.3    Cox, G.A.4    King Jr., L.E.5
  • 71
    • 33846623330 scopus 로고    scopus 로고
    • Genomewide scan for linkage reveals evidence of several susceptibility loci for alopecia areata
    • Martinez-Mir A., Zlotogorski A., Gordon D., Petukhova L., Mo J., Gilliam T.C., et al. Genomewide scan for linkage reveals evidence of several susceptibility loci for alopecia areata. Am J Hum Genet 80 (2007) 316-328
    • (2007) Am J Hum Genet , vol.80 , pp. 316-328
    • Martinez-Mir, A.1    Zlotogorski, A.2    Gordon, D.3    Petukhova, L.4    Mo, J.5    Gilliam, T.C.6
  • 73
    • 45049084949 scopus 로고    scopus 로고
    • Onset of alopecia areata after Epstein-Barr virus infectious mononucleosis
    • Rodriguez T.A., and Duvic M. Onset of alopecia areata after Epstein-Barr virus infectious mononucleosis. J Am Acad Dermatol 59 (2008) 137-139
    • (2008) J Am Acad Dermatol , vol.59 , pp. 137-139
    • Rodriguez, T.A.1    Duvic, M.2
  • 74
    • 0014036223 scopus 로고
    • Produced alopecia areata based on the focal infection theory and mental motive theory
    • Ikeda T. Produced alopecia areata based on the focal infection theory and mental motive theory. Dermatologica 134 (1967) 1-11
    • (1967) Dermatologica , vol.134 , pp. 1-11
    • Ikeda, T.1
  • 76
    • 0030752856 scopus 로고    scopus 로고
    • Stress and alopecia areata: a psychodermatologic study
    • Gupta M.A., Gupta A.K., and Watteel G.N. Stress and alopecia areata: a psychodermatologic study. Acta Derm Venereol 77 (1997) 296-298
    • (1997) Acta Derm Venereol , vol.77 , pp. 296-298
    • Gupta, M.A.1    Gupta, A.K.2    Watteel, G.N.3
  • 78
    • 0942266093 scopus 로고    scopus 로고
    • Roles of stress, stress perception and trait-anxiety in the onset and course of alopecia areata
    • Brajac I., Tkalcic M., Dragojevic D.M., and Gruber F. Roles of stress, stress perception and trait-anxiety in the onset and course of alopecia areata. J Dermatol 30 (2003) 871-878
    • (2003) J Dermatol , vol.30 , pp. 871-878
    • Brajac, I.1    Tkalcic, M.2    Dragojevic, D.M.3    Gruber, F.4
  • 79
    • 2642516609 scopus 로고    scopus 로고
    • The role of psychological factors in alopecia areata and the impact of the disease on the quality of life
    • Gulec A.T., Tanriverdi N., Duru C., Saray Y., and Akcali C. The role of psychological factors in alopecia areata and the impact of the disease on the quality of life. Int J Dermatol 43 (2004) 352-356
    • (2004) Int J Dermatol , vol.43 , pp. 352-356
    • Gulec, A.T.1    Tanriverdi, N.2    Duru, C.3    Saray, Y.4    Akcali, C.5
  • 81
    • 33846953200 scopus 로고    scopus 로고
    • A case series of alopecia areata in children: impact of personal and family history of stress and autoimmunity
    • Kakourou T., Karachristou K., and Chrousos G. A case series of alopecia areata in children: impact of personal and family history of stress and autoimmunity. J Eur Acad Dermatol Venereol 21 (2007) 356-359
    • (2007) J Eur Acad Dermatol Venereol , vol.21 , pp. 356-359
    • Kakourou, T.1    Karachristou, K.2    Chrousos, G.3
  • 83
    • 34248508667 scopus 로고    scopus 로고
    • Substance P as an immunomodulatory neuropeptide in a mouse model for autoimmune hair loss (alopecia areata)
    • Siebenhaar F., Sharov A.A., Peters E.M., Sharova T.Y., Syska W., Mardaryev A.N., et al. Substance P as an immunomodulatory neuropeptide in a mouse model for autoimmune hair loss (alopecia areata). J Invest Dermatol 127 (2007) 1489-1497
    • (2007) J Invest Dermatol , vol.127 , pp. 1489-1497
    • Siebenhaar, F.1    Sharov, A.A.2    Peters, E.M.3    Sharova, T.Y.4    Syska, W.5    Mardaryev, A.N.6
  • 84
    • 0035125256 scopus 로고    scopus 로고
    • Expression of neuropeptide-degrading enzymes in alopecia areata: an immunohistochemical study
    • Toyoda M., Makino T., Kagoura M., and Morohashi M. Expression of neuropeptide-degrading enzymes in alopecia areata: an immunohistochemical study. Br J Dermatol 144 (2001) 46-54
    • (2001) Br J Dermatol , vol.144 , pp. 46-54
    • Toyoda, M.1    Makino, T.2    Kagoura, M.3    Morohashi, M.4
  • 85
    • 66149140289 scopus 로고    scopus 로고
    • Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model
    • Zhang X., Yu M., Yu W., Weinberg J., Shapiro J., and McElwee K.J. Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model. J Invest Dermatol 129 (2009) 1527-1538
    • (2009) J Invest Dermatol , vol.129 , pp. 1527-1538
    • Zhang, X.1    Yu, M.2    Yu, W.3    Weinberg, J.4    Shapiro, J.5    McElwee, K.J.6
  • 86
    • 0028919313 scopus 로고
    • The basis of autoimmunity: part II. Genetic predisposition
    • Theofilopoulos A.N. The basis of autoimmunity: part II. Genetic predisposition. Immunol Today 16 (1995) 150-159
    • (1995) Immunol Today , vol.16 , pp. 150-159
    • Theofilopoulos, A.N.1
  • 87
    • 0028869486 scopus 로고
    • The basis of autoimmunity: part I. Mechanisms of aberrant self-recognition
    • Theofilopoulos A.N. The basis of autoimmunity: part I. Mechanisms of aberrant self-recognition. Immunol Today 16 (1995) 90-98
    • (1995) Immunol Today , vol.16 , pp. 90-98
    • Theofilopoulos, A.N.1
  • 88
    • 20444485767 scopus 로고    scopus 로고
    • Fazekas de St Groth B, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoimmunity
    • Goodnow C.C., and Sprent J. Fazekas de St Groth B, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature 435 (2005) 590-597
    • (2005) Nature , vol.435 , pp. 590-597
    • Goodnow, C.C.1    Sprent, J.2
  • 89
    • 34447098797 scopus 로고    scopus 로고
    • Multistep pathogenesis of autoimmune disease
    • Goodnow C.C. Multistep pathogenesis of autoimmune disease. Cell 130 (2007) 25-35
    • (2007) Cell , vol.130 , pp. 25-35
    • Goodnow, C.C.1
  • 92
    • 1542379709 scopus 로고    scopus 로고
    • Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model
    • Ito T., Ito N., Bettermann A., Tokura Y., Takigawa M., and Paus R. Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model. Am J Pathol 164 (2004) 623-634
    • (2004) Am J Pathol , vol.164 , pp. 623-634
    • Ito, T.1    Ito, N.2    Bettermann, A.3    Tokura, Y.4    Takigawa, M.5    Paus, R.6
  • 94
    • 0019457529 scopus 로고
    • Apoptosis as the mechanism of the involution of hair follicles in catagen transformation
    • Weedon D., and Strutton G. Apoptosis as the mechanism of the involution of hair follicles in catagen transformation. Acta Derm Venereol 61 (1981) 335-339
    • (1981) Acta Derm Venereol , vol.61 , pp. 335-339
    • Weedon, D.1    Strutton, G.2
  • 96
    • 0031883889 scopus 로고    scopus 로고
    • Clusters of perifollicular macrophages in normal murine skin: physiological degeneration of selected hair follicles by programmed organ deletion
    • Eichmuller S., van der Veen C., Moll I., Hermes B., Hofmann U., Muller-Rover S., et al. Clusters of perifollicular macrophages in normal murine skin: physiological degeneration of selected hair follicles by programmed organ deletion. J Histochem Cytochem 46 (1998) 361-370
    • (1998) J Histochem Cytochem , vol.46 , pp. 361-370
    • Eichmuller, S.1    van der Veen, C.2    Moll, I.3    Hermes, B.4    Hofmann, U.5    Muller-Rover, S.6
  • 97
    • 0014601097 scopus 로고
    • Role of macrophages in collagen resorption during hair growth cycle
    • Parakkal P.F. Role of macrophages in collagen resorption during hair growth cycle. J Ultrastruct Res 29 (1969) 210-217
    • (1969) J Ultrastruct Res , vol.29 , pp. 210-217
    • Parakkal, P.F.1
  • 98
    • 0030028886 scopus 로고    scopus 로고
    • The DEBR rat, alopecia areata and autoantibodies to the hair follicle
    • McElwee K.J., Pickett P., and Oliver R.F. The DEBR rat, alopecia areata and autoantibodies to the hair follicle. Br J Dermatol 134 (1996) 55-63
    • (1996) Br J Dermatol , vol.134 , pp. 55-63
    • McElwee, K.J.1    Pickett, P.2    Oliver, R.F.3
  • 99
    • 0030808547 scopus 로고    scopus 로고
    • Autoantibodies to hair follicles in C3H/HeJ mice with alopecia areata-like hair loss
    • Tobin D.J., Sundberg J.P., King Jr. L.E., Boggess D., and Bystryn J.C. Autoantibodies to hair follicles in C3H/HeJ mice with alopecia areata-like hair loss. J Invest Dermatol 109 (1997) 329-333
    • (1997) J Invest Dermatol , vol.109 , pp. 329-333
    • Tobin, D.J.1    Sundberg, J.P.2    King Jr., L.E.3    Boggess, D.4    Bystryn, J.C.5
  • 102
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • Albert M.L., Sauter B., and Bhardwaj N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392 (1998) 86-89
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 103
    • 0037222826 scopus 로고    scopus 로고
    • Dendritic cells under investigation in autoimmune disease
    • Mehling A., and Beissert S. Dendritic cells under investigation in autoimmune disease. Crit Rev Biochem Mol Biol 38 (2003) 1-21
    • (2003) Crit Rev Biochem Mol Biol , vol.38 , pp. 1-21
    • Mehling, A.1    Beissert, S.2
  • 104
    • 0036277647 scopus 로고    scopus 로고
    • Transient CD44 variant isoform expression and reduction in CD4(+)/CD25(+) regulatory T cells in C3H/HeJ mice with alopecia areata
    • Zoller M., McElwee K.J., Engel P., and Hoffmann R. Transient CD44 variant isoform expression and reduction in CD4(+)/CD25(+) regulatory T cells in C3H/HeJ mice with alopecia areata. J Invest Dermatol 118 (2002) 983-992
    • (2002) J Invest Dermatol , vol.118 , pp. 983-992
    • Zoller, M.1    McElwee, K.J.2    Engel, P.3    Hoffmann, R.4


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