메뉴 건너뛰기




Volumn 211, Issue 1, 2005, Pages 47-53

What can we learn from animal models of alopecia areata?

Author keywords

Animal models; Autoimmune diseases; Hair loss; Inflammation

Indexed keywords

ALOPECIA AREATA; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BIOCHEMISTRY; CELL TYPE; GENETICS; HAIR FOLLICLE; HAIR GROWTH; HAIR LOSS; IMMUNE SYSTEM; MELANOCYTE; NONHUMAN; PATHOGENESIS; PATHOGENICITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; T LYMPHOCYTE;

EID: 21344468115     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000085580     Document Type: Review
Times cited : (34)

References (67)
  • 2
    • 0000642469 scopus 로고
    • Alopecia areata: An evaluation of 736 patients
    • Muller SA, Winkelmann RK: Alopecia areata: An evaluation of 736 patients. Arch Dermatol 1963;88:290-297.
    • (1963) Arch Dermatol , vol.88 , pp. 290-297
    • Muller, S.A.1    Winkelmann, R.K.2
  • 5
    • 21344452850 scopus 로고
    • Case of area Celsi (porrigo decalvans), in which the parts were examined after death
    • Duckworth D: Case of area Celsi (porrigo decalvans), in which the parts were examined after death. Trans Pathol Soc 1882;33:386-392.
    • (1882) Trans Pathol Soc , vol.33 , pp. 386-392
    • Duckworth, D.1
  • 6
    • 0007723682 scopus 로고
    • Recherches sur l'histologic pathologique de la pelade
    • Giovannini S: Recherches sur l'histologic pathologique de la pelade. Ann Dermatol Syphiligr 1891;3:921-957.
    • (1891) Ann Dermatol Syphiligr , vol.3 , pp. 921-957
    • Giovannini, S.1
  • 7
    • 70449206855 scopus 로고
    • Morphologic changes in pilosebaceous units and anagen hairs in alopecia areata
    • Van Scott EJ: Morphologic changes in pilosebaceous units and anagen hairs in alopecia areata. J Invest Dermatol 1958;31:35-43.
    • (1958) J Invest Dermatol , vol.31 , pp. 35-43
    • Van Scott, E.J.1
  • 8
    • 0035830294 scopus 로고    scopus 로고
    • Is alopecia areata an autoimmune disease?
    • Randall VA: Is alopecia areata an autoimmune disease? Lancet 2001;358:1922-1924.
    • (2001) Lancet , vol.358 , pp. 1922-1924
    • Randall, V.A.1
  • 11
    • 0027704964 scopus 로고
    • Is alopecia areata an autoimmune response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?
    • Paus R, Slominski A, Czarnetzki BM: Is alopecia areata an autoimmune response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb? Yale J Biol Med 1993;66:541-554.
    • (1993) Yale J Biol Med , vol.66 , pp. 541-554
    • Paus, R.1    Slominski, A.2    Czarnetzki, B.M.3
  • 12
    • 43949162155 scopus 로고
    • Defining criteria for autoimmune diseases (Witebsky's postulates revisited)
    • Rose NR, Bona C: Defining criteria for autoimmune diseases (Witebsky's postulates revisited). Immunol Today 1993;14:426-430.
    • (1993) Immunol Today , vol.14 , pp. 426-430
    • Rose, N.R.1    Bona, C.2
  • 13
    • 0021348285 scopus 로고
    • Immunohistochemical analysis of T-cell subsets in the peribulbar and intrabulbar infiltrates of alopecia areata
    • Perret C, Wiesner-Menzel L, Happle R: Immunohistochemical analysis of T-cell subsets in the peribulbar and intrabulbar infiltrates of alopecia areata. Acta Derm Venereol 1984;64:26-30.
    • (1984) Acta Derm Venereol , vol.64 , pp. 26-30
    • Perret, C.1    Wiesner-Menzel, L.2    Happle, R.3
  • 14
    • 0021279565 scopus 로고
    • Immunohistochemical and electron microscopic characterization of the cellular infiltrate in alopecia (areata, totalis, and universalis)
    • Ranki A, Kianto U, Kanerva L, Tolvanen E, Johansson E: Immunohistochemical and electron microscopic characterization of the cellular infiltrate in alopecia (areata, totalis, and universalis). J Invest Dermatol 1984;83:7-11.
    • (1984) J Invest Dermatol , vol.83 , pp. 7-11
    • Ranki, A.1    Kianto, U.2    Kanerva, L.3    Tolvanen, E.4    Johansson, E.5
  • 15
    • 0021186186 scopus 로고
    • Intrabulbar and peribulbar accumulation of dendritic OKT 6-positive cells in alopecia areata
    • Wiesner-Menzel L, Happle R: Intrabulbar and peribulbar accumulation of dendritic OKT 6-positive cells in alopecia areata. Arch Dermatol Res 1984;276:333-334.
    • (1984) Arch Dermatol Res , vol.276 , pp. 333-334
    • Wiesner-Menzel, L.1    Happle, R.2
  • 17
    • 0037337092 scopus 로고    scopus 로고
    • Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes
    • Tang L, Cao L, Bernardo O, Chen Y, Sundberg JP, Lui H, Chung S, Shapiro J: Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes. J Invest Dermatol 2003;120:400-406.
    • (2003) J Invest Dermatol , vol.120 , pp. 400-406
    • Tang, L.1    Cao, L.2    Bernardo, O.3    Chen, Y.4    Sundberg, J.P.5    Lui, H.6    Chung, S.7    Shapiro, J.8
  • 18
    • 0842264834 scopus 로고    scopus 로고
    • Restoration of hair growth in mice with an alopecia areata-like disease using topical anthralin
    • Tang L, Cao L, Sundberg JP, Lui H, Shapiro J: Restoration of hair growth in mice with an alopecia areata-like disease using topical anthralin. Exp Dermatol 2004;13:5-10.
    • (2004) Exp Dermatol , vol.13 , pp. 5-10
    • Tang, L.1    Cao, L.2    Sundberg, J.P.3    Lui, H.4    Shapiro, J.5
  • 20
    • 0027436068 scopus 로고
    • HLA and ICAM-1 expression in alopecia areata in vivo and in vitro: The role of cytokines
    • Mcdonagh AJ, Snowden JA, Stierle C, Elliott K, Messenger AG: HLA and ICAM-1 expression in alopecia areata in vivo and in vitro: The role of cytokines. Br J Dermatol 1993;129:250-256.
    • (1993) Br J Dermatol , vol.129 , pp. 250-256
    • Mcdonagh, A.J.1    Snowden, J.A.2    Stierle, C.3    Elliott, K.4    Messenger, A.G.5
  • 22
    • 0033370140 scopus 로고    scopus 로고
    • The genetic basis of alopecia areata: HLA associations with patchy alopecia areata versus alopecia totalis and alopecia universalis
    • Colombe BW, Lou CD, Price VH: The genetic basis of alopecia areata: HLA associations with patchy alopecia areata versus alopecia totalis and alopecia universalis. J Invest Dermatol Symp Proc 1999;4:216-219.
    • (1999) J Invest Dermatol Symp Proc , vol.4 , pp. 216-219
    • Colombe, B.W.1    Lou, C.D.2    Price, V.H.3
  • 23
    • 0344430158 scopus 로고    scopus 로고
    • Alopecia areata after allogeneic bone marrow transplantation from an affected, human leukocyte antigen-matched sibling
    • Barahmani N, Whaley K, Duvic M: Alopecia areata after allogeneic bone marrow transplantation from an affected, human leukocyte antigen-matched sibling. J Am Acad Dermatol 2003;49:1192.
    • (2003) J Am Acad Dermatol , vol.49 , pp. 1192
    • Barahmani, N.1    Whaley, K.2    Duvic, M.3
  • 24
    • 0842329049 scopus 로고    scopus 로고
    • Simultaneous onset of chronic graft versus host disease and alopecia areata following allogeneic haematopoietic cell transplantation
    • Sanli H, Kusak F, Arat M, Ekmekci P, Ilhan O: Simultaneous onset of chronic graft versus host disease and alopecia areata following allogeneic haematopoietic cell transplantation. Acta Derm Venereol 2004;84:86-87.
    • (2004) Acta Derm Venereol , vol.84 , pp. 86-87
    • Sanli, H.1    Kusak, F.2    Arat, M.3    Ekmekci, P.4    Ilhan, O.5
  • 25
    • 19344370236 scopus 로고    scopus 로고
    • Mouse models of human autoimmune diseases: Essential tools that require the proper controls
    • Morel L: Mouse models of human autoimmune diseases: Essential tools that require the proper controls. Plos Biol 2004;2:E241.
    • (2004) Plos Biol , vol.2
    • Morel, L.1
  • 26
    • 0023259914 scopus 로고
    • Hair growth in scalp grafts from patients with alopecia areata and alopecia universalis grafted onto nude mice
    • Gilhar A, Krueger GG: Hair growth in scalp grafts from patients with alopecia areata and alopecia universalis grafted onto nude mice. Arch Dermatol 1987;123:44-50.
    • (1987) Arch Dermatol , vol.123 , pp. 44-50
    • Gilhar, A.1    Krueger, G.G.2
  • 27
    • 0031974909 scopus 로고    scopus 로고
    • Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice
    • Gilhar A, Ullmann Y, Berkutzki T, Assy B, Kalish RS: Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice. J Clin Invest 1998;101:62-67.
    • (1998) J Clin Invest , vol.101 , pp. 62-67
    • Gilhar, A.1    Ullmann, Y.2    Berkutzki, T.3    Assy, B.4    Kalish, R.S.5
  • 29
    • 0031789151 scopus 로고    scopus 로고
    • Equine alopecia areata autoantibodies target multiple hair follicle antigens and may alter hair growth: A preliminary study
    • Tobin DJ, Alhaidari Z, Olivry T: Equine alopecia areata autoantibodies target multiple hair follicle antigens and may alter hair growth: A preliminary study. Exp Dermatol 1998;7:289-297.
    • (1998) Exp Dermatol , vol.7 , pp. 289-297
    • Tobin, D.J.1    Alhaidari, Z.2    Olivry, T.3
  • 32
    • 0033390153 scopus 로고    scopus 로고
    • Alopecia areata and universalis in the Smyth chicken model for spontaneous autoimmune vitiligo
    • Smyth JR Jr, McNeil M: Alopecia areata and universalis in the Smyth chicken model for spontaneous autoimmune vitiligo. J Invest Dermatol Symp Proc 1999;4:211-215.
    • (1999) J Invest Dermatol Symp Proc , vol.4 , pp. 211-215
    • Smyth Jr., J.R.1    McNeil, M.2
  • 35
    • 0028277447 scopus 로고
    • Immunohistological study of the development of the cellular infiltrate in the pelage follicles of the DEBR model for alopecia areata
    • Zhang JG, Oliver RF: Immunohistological study of the development of the cellular infiltrate in the pelage follicles of the DEBR model for alopecia areata. Br J Dermatol 1994;130:405-414.
    • (1994) Br J Dermatol , vol.130 , pp. 405-414
    • Zhang, J.G.1    Oliver, R.F.2
  • 36
    • 0030028886 scopus 로고    scopus 로고
    • The DEBR rat, alopecia areata and autoantibodies to the hair follicle
    • McElwee KJ, Pickett P, Oliver RF: The DEBR rat, alopecia areata and autoantibodies to the hair follicle. Br J Dermatol 1996;134:55-63.
    • (1996) Br J Dermatol , vol.134 , pp. 55-63
    • McElwee, K.J.1    Pickett, P.2    Oliver, R.F.3
  • 38
    • 1542706083 scopus 로고    scopus 로고
    • Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss
    • McElwee KJ, Silva K, Boggess D, Bechtold L, King LE Jr, Sundberg JP: Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss. Vet Pathol 2003;40:643-650.
    • (2003) Vet Pathol , vol.40 , pp. 643-650
    • McElwee, K.J.1    Silva, K.2    Boggess, D.3    Bechtold, L.4    King Jr., L.E.5    Sundberg, J.P.6
  • 39
    • 0031738760 scopus 로고    scopus 로고
    • Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts
    • McElwee KJ, Boggess D, King LE Jr, Sundberg JP: Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts. J Invest Dermatol 1998;111:797-803.
    • (1998) J Invest Dermatol , vol.111 , pp. 797-803
    • McElwee, K.J.1    Boggess, D.2    King Jr., L.E.3    Sundberg, J.P.4
  • 40
    • 0036038262 scopus 로고    scopus 로고
    • Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans
    • Carroll JM, McElwee KJ, King LE, Byrne MC, Sundberg JP: Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans. J Invest Dermatol 2002;119:392-402.
    • (2002) J Invest Dermatol , vol.119 , pp. 392-402
    • Carroll, J.M.1    McElwee, K.J.2    King, L.E.3    Byrne, M.C.4    Sundberg, J.P.5
  • 41
    • 0036911686 scopus 로고    scopus 로고
    • Resistance to alopecia areata in C3H/HeJ mice is associated with increased expression of regulatory cytokines and a failure to recruit CD4+ and CD8+ cells
    • McElwee KJ, Hoffmann R, Freyschmidt-Paul P, Wenzel E, Kissling S, Sundberg JP, Zöller M: Resistance to alopecia areata in C3H/HeJ mice is associated with increased expression of regulatory cytokines and a failure to recruit CD4+ and CD8+ cells. J Invest Dermatol 2002;119:1426-1433.
    • (2002) J Invest Dermatol , vol.119 , pp. 1426-1433
    • McElwee, K.J.1    Hoffmann, R.2    Freyschmidt-Paul, P.3    Wenzel, E.4    Kissling, S.5    Sundberg, J.P.6    Zöller, M.7
  • 42
    • 0036277647 scopus 로고    scopus 로고
    • Transient CD44 variant isoform expression and reduction in CD4(+)/CD25(+) regulatory T cells in C3H/HeJ mice with alopecia areata
    • Zöller M, McElwee KJ, Engel P, Hoffmann R: Transient CD44 variant isoform expression and reduction in CD4(+)/CD25(+) regulatory T cells in C3H/HeJ mice with alopecia areata. J Invest Dermatol 2002;118:983-992.
    • (2002) J Invest Dermatol , vol.118 , pp. 983-992
    • Zöller, M.1    McElwee, K.J.2    Engel, P.3    Hoffmann, R.4
  • 43
    • 0030003391 scopus 로고    scopus 로고
    • In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata
    • McElwee KJ, Spiers EM, Oliver RF: In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata. Br J Dermatol 1996;135:211-217.
    • (1996) Br J Dermatol , vol.135 , pp. 211-217
    • McElwee, K.J.1    Spiers, E.M.2    Oliver, R.F.3
  • 44
    • 0032912467 scopus 로고    scopus 로고
    • Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T cells
    • McElwee KJ, Spiers EM, Oliver RF: Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T cells. Br J Dermatol 1999;140:432-437.
    • (1999) Br J Dermatol , vol.140 , pp. 432-437
    • McElwee, K.J.1    Spiers, E.M.2    Oliver, R.F.3
  • 46
    • 18244400239 scopus 로고    scopus 로고
    • Transfer of CD8 cells induces localized hair loss whereas CD4/CD25 cells promote systemic alopecia areata and CD4/CD25 cells blockade disease onset in the C3H/HeJ mouse model
    • McElwee KJ, Freyschmidt-Paul P, Hoffmann R, Kissling S, Hummel S, Vitacolonna M, Zöller M: Transfer of CD8 cells induces localized hair loss whereas CD4/CD25 cells promote systemic alopecia areata and CD4/CD25 cells blockade disease onset in the C3H/HeJ mouse model. J Invest Dermatol 2005;124:947-957.
    • (2005) J Invest Dermatol , vol.124 , pp. 947-957
    • McElwee, K.J.1    Freyschmidt-Paul, P.2    Hoffmann, R.3    Kissling, S.4    Hummel, S.5    Vitacolonna, M.6    Zöller, M.7
  • 49
    • 14244250952 scopus 로고    scopus 로고
    • Apoptosis resistance in peripheral blood lymphocytes of alopecia areata patients
    • Zöller M, McElwee KJ, Vitacolonna M, Hoffmann R: Apoptosis resistance in peripheral blood lymphocytes of alopecia areata patients. J Autoimmun 2004;23:241-256.
    • (2004) J Autoimmun , vol.23 , pp. 241-256
    • Zöller, M.1    McElwee, K.J.2    Vitacolonna, M.3    Hoffmann, R.4
  • 50
    • 4043145727 scopus 로고    scopus 로고
    • The progressive state, in contrast to the stable or regressive state of alopecia areata, is reflected in peripheral blood mononuclear cells
    • Zöller M, McElwee KJ, Vitacolonna M, Hoffmann R: The progressive state, in contrast to the stable or regressive state of alopecia areata, is reflected in peripheral blood mononuclear cells. Exp Dermatol 2004;13:435-444.
    • (2004) Exp Dermatol , vol.13 , pp. 435-444
    • Zöller, M.1    McElwee, K.J.2    Vitacolonna, M.3    Hoffmann, R.4
  • 53
    • 15244354491 scopus 로고    scopus 로고
    • De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- Cells
    • Walker MR, Carson BD, Nepom GT, Ziegler SF, Buckner JH: De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells. Proc Natl Acad Sci USA 2005;102:4103-4108.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4103-4108
    • Walker, M.R.1    Carson, B.D.2    Nepom, G.T.3    Ziegler, S.F.4    Buckner, J.H.5
  • 54
    • 0041868060 scopus 로고    scopus 로고
    • Fas-deficient C3.MRL-Tnfrsf6(lpr) mice and Fas ligand-deficient C3H/HeJ-Tnfsf6(gld) mice are relatively resistant to the induction of alopecia areata by grafting of alopecia areata-affected skin from C3H/HeJ mice
    • Freyschmidt-Paul P, McElwee KJ, Botchkarev V, Kissling S, Wenzel E, Sundberg JP, Happle R, Hoffmann R: Fas-deficient C3.MRL-Tnfrsf6(lpr) mice and Fas ligand-deficient C3H/HeJ-Tnfsf6(gld) mice are relatively resistant to the induction of alopecia areata by grafting of alopecia areata-affected skin from C3H/HeJ mice. J Invest Dermatol Symp Proc 2003;8:104-108.
    • (2003) J Invest Dermatol Symp Proc , vol.8 , pp. 104-108
    • Freyschmidt-Paul, P.1    McElwee, K.J.2    Botchkarev, V.3    Kissling, S.4    Wenzel, E.5    Sundberg, J.P.6    Happle, R.7    Hoffmann, R.8
  • 57
  • 60
    • 0028201732 scopus 로고
    • Tolerance, danger and the extended family
    • Matzinger P: Tolerance, danger and the extended family. Annu Rev Immunol 1994;12:991-1045.
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 61
    • 0028869486 scopus 로고
    • The basis of autoimmunity. I. Mechanisms of aberrant self-recognition
    • Theofilopoulos AN: The basis of autoimmunity. I. Mechanisms of aberrant self-recognition. Immunol Today 1995;16:90-98.
    • (1995) Immunol Today , vol.16 , pp. 90-98
    • Theofilopoulos, A.N.1
  • 62
    • 0028919313 scopus 로고
    • The basis of autoimmunity. II. Genetic predisposition
    • Theofilopoulos AN: The basis of autoimmunity. II. Genetic predisposition. Immunol Today 1995;16:150-159.
    • (1995) Immunol Today , vol.16 , pp. 150-159
    • Theofilopoulos, A.N.1
  • 63
    • 0034773019 scopus 로고    scopus 로고
    • Mechanisms for the induction of autoimmunity by infectious agents
    • Wucherpfennig KW: Mechanisms for the induction of autoimmunity by infectious agents. J Clin Invest 2001;108:1097-1104.
    • (2001) J Clin Invest , vol.108 , pp. 1097-1104
    • Wucherpfennig, K.W.1
  • 64
    • 0036595050 scopus 로고    scopus 로고
    • T-cell signalling and autoimmunity: Molecular mechanisms of disease
    • Ohashi PS: T-cell signalling and autoimmunity: Molecular mechanisms of disease. Nat Rev Immunol 2002;2:427-438.
    • (2002) Nat Rev Immunol , vol.2 , pp. 427-438
    • Ohashi, P.S.1
  • 66
    • 0346243854 scopus 로고    scopus 로고
    • Histopathologic features of alopecia areata: A new look
    • Whiting DA: Histopathologic features of alopecia areata: A new look. Arch Dermatol 2003;139:1555-1559.
    • (2003) Arch Dermatol , vol.139 , pp. 1555-1559
    • Whiting, D.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.