-
1
-
-
0037586498
-
AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
-
Anand, S., S. Penrhyn-Lowe, and A.R. Venkitaraman. 2003. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell. 3:51-62.
-
(2003)
Cancer Cell
, vol.3
, pp. 51-62
-
-
Anand, S.1
Penrhyn-Lowe, S.2
Venkitaraman, A.R.3
-
3
-
-
58849164887
-
Cystic kidney diseases and planar cell polarity signaling
-
Bacallao, R.L., and H. McNeill. 2009. Cystic kidney diseases and planar cell polarity signaling. Clin. Genet. 75:107-117.
-
(2009)
Clin. Genet.
, vol.75
, pp. 107-117
-
-
Bacallao, R.L.1
McNeill, H.2
-
4
-
-
50849100989
-
Loss of polycystin-1 causes centrosome amplification and genomic instability
-
Battini, L., S. Macip, E. Fedorova, S. Dikman, S. Somlo, C. Montagna, and G.L. Gusella. 2008. Loss of polycystin-1 causes centrosome amplification and genomic instability. Hum. Mol. Genet. 17:2819-2833.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 2819-2833
-
-
Battini, L.1
Macip, S.2
Fedorova, E.3
Dikman, S.4
Somlo, S.5
Montagna, C.6
Gusella, G.L.7
-
5
-
-
0242330123
-
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
-
Bayliss, R., T. Sardon, I. Vernos, and E. Conti. 2003. Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol. Cell. 12:851-862.
-
(2003)
Mol. Cell.
, vol.12
, pp. 851-862
-
-
Bayliss, R.1
Sardon, T.2
Vernos, I.3
Conti, E.4
-
6
-
-
33646778485
-
Cilium-generated signaling: a cellular GPS?
-
Benzing, T., and G. Walz. 2006. Cilium-generated signaling: a cellular GPS? Curr. Opin. Nephrol. Hypertens. 15:245-249.
-
(2006)
Curr. Opin. Nephrol. Hypertens.
, vol.15
, pp. 245-249
-
-
Benzing, T.1
Walz, G.2
-
7
-
-
0032100685
-
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
-
Bischoff, J.R., L. Anderson, Y. Zhu, K. Mossie, L. Ng, B. Souza, B. Schryver, P. Flanagan, F. Clairvoyant, C. Ginther, et al. 1998. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J. 17:3052-3065.
-
(1998)
EMBO J
, vol.17
, pp. 3052-3065
-
-
Bischoff, J.R.1
Anderson, L.2
Zhu, Y.3
Mossie, K.4
Ng, L.5
Souza, B.6
Schryver, B.7
Flanagan, P.8
Clairvoyant, F.9
Ginther, C.10
-
8
-
-
52949115290
-
Centrosome overduplication and mitotic instability in PKD2 transgenic lines
-
Burtey, S., M. Riera, E. Ribe, P. Pennenkamp, R. Rance, J. Luciani, B. Dworniczak, M.G. Mattei, and M. Fontés. 2008. Centrosome overduplication and mitotic instability in PKD2 transgenic lines. Cell Biol. Int. 32:1193-1198.
-
(2008)
Cell Biol. Int.
, vol.32
, pp. 1193-1198
-
-
Burtey, S.1
Riera, M.2
Ribe, E.3
Pennenkamp, P.4
Rance, R.5
Luciani, J.6
Dworniczak, B.7
Mattei, M.G.8
Fontés, M.9
-
9
-
-
0033214702
-
Identification and characterization of polycystin-2, the PKD2 gene product
-
Cai, Y., Y. Maeda, A. Cedzich, V.E. Torres, G. Wu, T. Hayashi, T. Mochizuki, J.H. Park, R. Witzgall, and S. Somlo. 1999. Identification and characterization of polycystin-2, the PKD2 gene product. J. Biol. Chem. 274:28557- 28565.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28557-28565
-
-
Cai, Y.1
Maeda, Y.2
Cedzich, A.3
Torres, V.E.4
Wu, G.5
Hayashi, T.6
Mochizuki, T.7
Park, J.H.8
Witzgall, R.9
Somlo, S.10
-
10
-
-
2442605494
-
Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812
-
Cai, Y., G. Anyatonwu, D. Okuhara, K.B. Lee, Z. Yu, T. Onoe, C.L. Mei, Q. Qian, L. Geng, R. Wiztgall, et al. 2004. Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812. J. Biol. Chem. 279:19987-19995.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 19987-19995
-
-
Cai, Y.1
Anyatonwu, G.2
Okuhara, D.3
Lee, K.B.4
Yu, Z.5
Onoe, T.6
Mei, C.L.7
Qian, Q.8
Geng, L.9
Wiztgall, R.10
-
11
-
-
0037047280
-
Calmodulin binds RalA and RalB and is required for the thrombin-induced activation of Ral in human platelets
-
Clough, R.R., R.S. Sidhu, and R.P. Bhullar. 2002. Calmodulin binds RalA and RalB and is required for the thrombin-induced activation of Ral in human platelets. J. Biol. Chem. 277:28972-28980.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28972-28980
-
-
Clough, R.R.1
Sidhu, R.S.2
Bhullar, R.P.3
-
12
-
-
76249102361
-
Experimental and computational studies indicate specific binding of pVHL protein to Aurora-A kinase
-
Ferchichi, I., N. Stambouli, R. Marrackchi, Y. Arlot, C. Prigent, A. Fadiel, K. Odunsi, A. Ben Ammar Elgaaied, and A. Hamza. 2010. Experimental and computational studies indicate specific binding of pVHL protein to Aurora-A kinase. J. Phys. Chem. B. 114:1486-1497.
-
(2010)
J. Phys. Chem. B.
, vol.114
, pp. 1486-1497
-
-
Ferchichi, I.1
Stambouli, N.2
Marrackchi, R.3
Arlot, Y.4
Prigent, C.5
Fadiel, A.6
Odunsi, K.7
Ben Ammar Elgaaied, A.8
Hamza, A.9
-
13
-
-
23944500328
-
Aurora-A site specificity: a study with synthetic peptide substrates
-
Ferrari, S., O. Marin, M.A. Pagano, F. Meggio, D. Hess, M. El-Shemerly, A. Krystyniak, and L.A. Pinna. 2005. Aurora-A site specificity: a study with synthetic peptide substrates. Biochem. J. 390:293-302.
-
(2005)
Biochem. J.
, vol.390
, pp. 293-302
-
-
Ferrari, S.1
Marin, O.2
Pagano, M.A.3
Meggio, F.4
Hess, D.5
El-Shemerly, M.6
Krystyniak, A.7
Pinna, L.A.8
-
14
-
-
29444450890
-
Defective planar cell polarity in polycystic kidney disease
-
Fischer, E., E. Legue, A. Doyen, F. Nato, J.F. Nicolas, V. Torres, M. Yaniv, and M. Pontoglio. 2006. Defective planar cell polarity in polycystic kidney disease. Nat. Genet. 38:21-23.
-
(2006)
Nat. Genet.
, vol.38
, pp. 21-23
-
-
Fischer, E.1
Legue, E.2
Doyen, A.3
Nato, F.4
Nicolas, J.F.5
Torres, V.6
Yaniv, M.7
Pontoglio, M.8
-
15
-
-
0034095229
-
Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene
-
Foggensteiner, L., A.P. Bevan, R. Thomas, N. Coleman, C. Boulter, J. Bradley, O. Ibraghimov-Beskrovnaya, K. Klinger, and R. Sandford. 2000. Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene. J. Am. Soc. Nephrol. 11:814-827.
-
(2000)
J. Am. Soc. Nephrol.
, vol.11
, pp. 814-827
-
-
Foggensteiner, L.1
Bevan, A.P.2
Thomas, R.3
Coleman, N.4
Boulter, C.5
Bradley, J.6
Ibraghimov-Beskrovnaya, O.7
Klinger, K.8
Sandford, R.9
-
16
-
-
67649687029
-
Calcimimetic inhibits late-stage cyst growth in ADPKD
-
Gattone, V.H. II, N.X. Chen, R.M. Sinders, M.F. Seifert, D. Duan, D. Martin, C. Henley, and S.M. Moe. 2009. Calcimimetic inhibits late-stage cyst growth in ADPKD. J. Am. Soc. Nephrol. 20:1527-1532.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 1527-1532
-
-
Gattone II., V.H.1
Chen, N.X.2
Sinders, R.M.3
Seifert, M.F.4
Duan, D.5
Martin, D.6
Henley, C.7
Moe, S.M.8
-
17
-
-
41549122837
-
Aurora kinases as anticancer drug targets
-
Gautschi, O., J. Heighway, P.C. Mack, P.R. Purnell, P.N. Lara Jr., and D.R. Gandara. 2008. Aurora kinases as anticancer drug targets. Clin. Cancer Res. 14:1639-1648.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 1639-1648
-
-
Gautschi, O.1
Heighway, J.2
Mack, P.C.3
Purnell, P.R.4
Lara Jr., P.N.5
Gandara, D.R.6
-
18
-
-
0034672628
-
Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation
-
Geng, L., C.R. Burrow, H.P. Li, and P.D. Wilson. 2000. Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation. Biochim. Biophys. Acta. 1535:21-35.
-
(2000)
Biochim. Biophys. Acta.
, vol.1535
, pp. 21-35
-
-
Geng, L.1
Burrow, C.R.2
Li, H.P.3
Wilson, P.D.4
-
19
-
-
57349156171
-
Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2
-
Geng, L., W. Boehmerle, Y. Maeda, D.Y. Okuhara, X. Tian, Z. Yu, C.U. Choe, G.I. Anyatonwu, B.E. Ehrlich, and S. Somlo. 2008. Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2. Proc. Natl. Acad. Sci. USA. 105:15920-15925.
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 15920-15925
-
-
Geng, L.1
Boehmerle, W.2
Maeda, Y.3
Okuhara, D.Y.4
Tian, X.5
Yu, Z.6
Choe, C.U.7
Anyatonwu, G.I.8
Ehrlich, B.E.9
Somlo, S.10
-
20
-
-
33747769976
-
The versatile nature of the calcium-permeable cation channel TRPP2
-
Giamarchi, A., F. Padilla, B. Coste, M. Raoux, M. Crest, E. Honoré, and P. Delmas. 2006. The versatile nature of the calcium-permeable cation channel TRPP2. EMBO Rep. 7:787-793.
-
(2006)
EMBO Rep
, vol.7
, pp. 787-793
-
-
Giamarchi, A.1
Padilla, F.2
Coste, B.3
Raoux, M.4
Crest, M.5
Honoré, E.6
Delmas, P.7
-
21
-
-
0037099531
-
Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis
-
Goepfert, T.M., Y.E. Adigun, L. Zhong, J. Gay, D. Medina, and W.R. Brinkley. 2002. Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis. Cancer Res. 62:4115-4122.
-
(2002)
Cancer Res
, vol.62
, pp. 4115-4122
-
-
Goepfert, T.M.1
Adigun, Y.E.2
Zhong, L.3
Gay, J.4
Medina, D.5
Brinkley, W.R.6
-
22
-
-
0141703576
-
Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells
-
Grimm, D.H., Y. Cai, V. Chauvet, V. Rajendran, R. Zeltner, L. Geng, E.D. Avner, W. Sweeney, S. Somlo, and M.J. Caplan. 2003. Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. J. Biol. Chem. 278:36786-36793.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36786-36793
-
-
Grimm, D.H.1
Cai, Y.2
Chauvet, V.3
Rajendran, V.4
Zeltner, R.5
Geng, L.6
Avner, E.D.7
Sweeney, W.8
Somlo, S.9
Caplan, M.J.10
-
23
-
-
0034700483
-
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
-
Hanaoka, K., F. Qian, A. Boletta, A.K. Bhunia, K. Piontek, L. Tsiokas, V.P. Sukhatme, W.B. Guggino, and G.G. Germino. 2000. Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents. Nature. 408:990-994.
-
(2000)
Nature
, vol.408
, pp. 990-994
-
-
Hanaoka, K.1
Qian, F.2
Boletta, A.3
Bhunia, A.K.4
Piontek, K.5
Tsiokas, L.6
Sukhatme, V.P.7
Guggino, W.B.8
Germino, G.G.9
-
24
-
-
77649215024
-
Chapter 2
-
F. E. Harrell Jr., editor. Springer, New York
-
Harrell, F.E., Jr. 2001. Chapter 2. In Regression Modeling Strategies: with applications to linear models, logistic regression, and survival analysis. F.E. Harrell Jr., editor. Springer, New York. 11-40.
-
(2001)
Regression Modeling Strategies: with applications to linear models, logistic regression, and survival analysis
, pp. 11-40
-
-
Harrell Jr., F.E.1
-
26
-
-
33746544622
-
Mitotic activation of the kinase Aurora-A requires its binding partner Bora
-
Hutterer, A., D. Berdnik, F. Wirtz-Peitz, M. Zigman, A. Schleiffer, and J.A. Knoblich. 2006. Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Dev. Cell. 11:147-157.
-
(2006)
Dev. Cell.
, vol.11
, pp. 147-157
-
-
Hutterer, A.1
Berdnik, D.2
Wirtz-Peitz, F.3
Zigman, M.4
Schleiffer, A.5
Knoblich, J.A.6
-
27
-
-
20144383835
-
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation
-
Köttgen, M., T. Benzing, T. Simmen, R. Tauber, B. Buchholz, S. Feliciangeli, T.B. Huber, B. Schermer, A. Kramer-Zucker, K. Höpker, et al. 2005. Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation. EMBO J. 24:705-716.
-
(2005)
EMBO J
, vol.24
, pp. 705-716
-
-
Köttgen, M.1
Benzing, T.2
Simmen, T.3
Tauber, R.4
Buchholz, B.5
Feliciangeli, S.6
Huber, T.B.7
Schermer, B.8
Kramer-Zucker, A.9
Höpker, K.10
-
28
-
-
0036122434
-
Polycystin-2 is an intracellular calcium release channel
-
Koulen, P., Y. Cai, L. Geng, Y. Maeda, S. Nishimura, R. Witzgall, B.E. Ehrlich, and S. Somlo. 2002. Polycystin-2 is an intracellular calcium release channel. Nat. Cell Biol. 4:191-197.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 191-197
-
-
Koulen, P.1
Cai, Y.2
Geng, L.3
Maeda, Y.4
Nishimura, S.5
Witzgall, R.6
Ehrlich, B.E.7
Somlo, S.8
-
29
-
-
33847414410
-
Significance of Aurora-A expression in renal cell carcinoma
-
Kurahashi, T., H. Miyake, I. Hara, and M. Fujisawa. 2007. Significance of Aurora-A expression in renal cell carcinoma. Urol. Oncol. 25:128-133.
-
(2007)
Urol. Oncol.
, vol.25
, pp. 128-133
-
-
Kurahashi, T.1
Miyake, H.2
Hara, I.3
Fujisawa, M.4
-
30
-
-
0029891787
-
Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae
-
Law, S.F., J. Estojak, B. Wang, T. Mysliwiec, G.D. Kruh, and E.A. Golemis. 1996. Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:3327-3337.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3327-3337
-
-
Law, S.F.1
Estojak, J.2
Wang, B.3
Mysliwiec, T.4
Kruh, G.D.5
Golemis, E.A.6
-
31
-
-
0031813880
-
Cell cycleregulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments
-
Law, S.F., Y.-Z. Zhang, A.J. Klein-Szanto, and E.A. Golemis. 1998. Cell cycleregulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments. Mol. Cell. Biol. 18: 3540-3551.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3540-3551
-
-
Law, S.F.1
Zhang, Y.-Z.2
Klein-Szanto, A.J.3
Golemis, E.A.4
-
32
-
-
0033544003
-
Dimerization of the docking/adaptor protein HEF1 via a carboxyterminal helix-loop-helix domain
-
Law, S.F., Y.-Z. Zhang, S.J. Fashena, G. Toby, J. Estojak, and E.A. Golemis. 1999. Dimerization of the docking/adaptor protein HEF1 via a carboxyterminal helix-loop-helix domain. Exp. Cell Res. 252:224-235.
-
(1999)
Exp. Cell Res.
, vol.252
, pp. 224-235
-
-
Law, S.F.1
Zhang, Y.-Z.2
Fashena, S.J.3
Toby, G.4
Estojak, J.5
Golemis, E.A.6
-
33
-
-
28544433252
-
Polycystin-1 and polycystin-2 regulate the cell cycle through the helixloop-helix inhibitor Id2
-
Li, X., Y. Luo, P.G. Starremans, C.A. McNamara, Y. Pei, and J. Zhou. 2005. Polycystin-1 and polycystin-2 regulate the cell cycle through the helixloop-helix inhibitor Id2. Nat. Cell Biol. 7:1202-1212.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 1202-1212
-
-
Li, X.1
Luo, Y.2
Starremans, P.G.3
McNamara, C.A.4
Pei, Y.5
Zhou, J.6
-
34
-
-
0041965735
-
Immortalized epithelial cells from human autosomal dominant polycystic kidney cysts
-
Loghman-Adham, M., S.M. Nauli, C.E. Soto, B. Kariuki, and J. Zhou. 2003. Immortalized epithelial cells from human autosomal dominant polycystic kidney cysts. Am. J. Physiol. Renal Physiol. 285:F397-F412.
-
(2003)
Am. J. Physiol. Renal Physiol.
, vol.285
-
-
Loghman-Adham, M.1
Nauli, S.M.2
Soto, C.E.3
Kariuki, B.4
Zhou, J.5
-
36
-
-
0037084163
-
Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells
-
Meraldi, P., R. Honda, and E.A. Nigg. 2002. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J. 21:483-492.
-
(2002)
EMBO J
, vol.21
, pp. 483-492
-
-
Meraldi, P.1
Honda, R.2
Nigg, E.A.3
-
37
-
-
69949167012
-
An essential role of the aPKCAurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics
-
Mori, D., M. Yamada, Y. Mimori-Kiyosue, Y. Shirai, A. Suzuki, S. Ohno, H. Saya, A. Wynshaw-Boris, and S. Hirotsune. 2009. An essential role of the aPKCAurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics. Nat. Cell Biol. 11:1057-1068.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1057-1068
-
-
Mori, D.1
Yamada, M.2
Mimori-Kiyosue, Y.3
Shirai, Y.4
Suzuki, A.5
Ohno, S.6
Saya, H.7
Wynshaw-Boris, A.8
Hirotsune, S.9
-
38
-
-
0037317302
-
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
-
Nauli, S.M., F.J. Alenghat, Y. Luo, E. Williams, P. Vassilev, X. Li, A.E. Elia, W. Lu, E.M. Brown, S.J. Quinn, et al. 2003. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat. Genet. 33:129-137.
-
(2003)
Nat. Genet.
, vol.33
, pp. 129-137
-
-
Nauli, S.M.1
Alenghat, F.J.2
Luo, Y.3
Williams, E.4
Vassilev, P.5
Li, X.6
Elia, A.E.7
Lu, W.8
Brown, E.M.9
Quinn, S.J.10
-
39
-
-
70350418719
-
Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions
-
Ogawa, H., N. Ohta, W. Moon, and F. Matsuzaki. 2009. Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions. J. Cell Sci. 122:3242-3249.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 3242-3249
-
-
Ogawa, H.1
Ohta, N.2
Moon, W.3
Matsuzaki, F.4
-
40
-
-
0034959232
-
Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics
-
O'Neill, G.M., and E.A. Golemis. 2001. Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Mol. Cell. Biol. 21:5094- 5108.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5094-5108
-
-
O'Neill, G.M.1
Golemis, E.A.2
-
41
-
-
1642406286
-
An aurora kinase is essential for flagellar disassembly in Chlamydomonas
-
Pan, J., Q. Wang, and W.J. Snell. 2004. An aurora kinase is essential for flagellar disassembly in Chlamydomonas. Dev. Cell. 6:445-451.
-
(2004)
Dev. Cell.
, vol.6
, pp. 445-451
-
-
Pan, J.1
Wang, Q.2
Snell, W.J.3
-
42
-
-
17144377111
-
Cilium-generated signaling and cilia-related disorders
-
Pan, J., Q. Wang, and W.J. Snell. 2005. Cilium-generated signaling and cilia-related disorders. Lab. Invest. 85:452-463.
-
(2005)
Lab. Invest.
, vol.85
, pp. 452-463
-
-
Pan, J.1
Wang, Q.2
Snell, W.J.3
-
43
-
-
78650077660
-
Rapid calcium-dependent activation of Aurora-A kinase
-
Plotnikova, O.V., E.N. Pugacheva, R.L. Dunbrack, and E.A. Golemis. 2010. Rapid calcium-dependent activation of Aurora-A kinase. Nat Commun. 1:64.
-
(2010)
Nat Commun
, vol.1
, pp. 64
-
-
Plotnikova, O.V.1
Pugacheva, E.N.2
Dunbrack, R.L.3
Golemis, E.A.4
-
44
-
-
27144495462
-
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
-
Pugacheva, E.N., and E.A. Golemis. 2005. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat. Cell Biol. 7:937-946.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 937-946
-
-
Pugacheva, E.N.1
Golemis, E.A.2
-
45
-
-
33645220356
-
HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks
-
Pugacheva, E.N., and E.A. Golemis. 2006. HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks. Cell Cycle. 5:384-391.
-
(2006)
Cell Cycle
, vol.5
, pp. 384-391
-
-
Pugacheva, E.N.1
Golemis, E.A.2
-
46
-
-
34250758641
-
HEF1-dependent Aurora A activation induces disassembly of the primary cilium
-
Pugacheva, E.N., S.A. Jablonski, T.R. Hartman, E.P. Henske, and E.A. Golemis. 2007. HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell. 129:1351-1363.
-
(2007)
Cell
, vol.129
, pp. 1351-1363
-
-
Pugacheva, E.N.1
Jablonski, S.A.2
Hartman, T.R.3
Henske, E.P.4
Golemis, E.A.5
-
47
-
-
0043133391
-
Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells
-
Qian, Q., L.W. Hunter, M. Li, M. Marin-Padilla, Y.S. Prakash, S. Somlo, P.C. Harris, V.E. Torres, and G.C. Sieck. 2003. Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells. Hum. Mol. Genet. 12:1875-1880.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1875-1880
-
-
Qian, Q.1
Hunter, L.W.2
Li, M.3
Marin-Padilla, M.4
Prakash, Y.S.5
Somlo, S.6
Harris, P.C.7
Torres, V.E.8
Sieck, G.C.9
-
49
-
-
0028010818
-
HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney
-
Ryan, M.J., G. Johnson, J. Kirk, S.M. Fuerstenberg, R.A. Zager, and B. Torok-Storb. 1994. HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney. Kidney Int. 45:48-57.
-
(1994)
Kidney Int
, vol.45
, pp. 48-57
-
-
Ryan, M.J.1
Johnson, G.2
Kirk, J.3
Fuerstenberg, S.M.4
Zager, R.A.5
Torok-Storb, B.6
-
50
-
-
34548357152
-
Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle
-
Singh, M., L. Cowell, S. Seo, G. O'Neill, and E. Golemis. 2007. Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle. Cell Biochem. Biophys. 48:54-72.
-
(2007)
Cell Biochem. Biophys.
, vol.48
, pp. 54-72
-
-
Singh, M.1
Cowell, L.2
Seo, S.3
O'Neill, G.4
Golemis, E.5
-
51
-
-
44949179470
-
A novel Cas family member, HEPL, regulates FAK and cell spreading
-
Singh, M.K., D. Dadke, E. Nicolas, I.G. Serebriiskii, S. Apostolou, A. Canutescu, B.L. Egleston, and E.A. Golemis. 2008. A novel Cas family member, HEPL, regulates FAK and cell spreading. Mol. Biol. Cell. 19:1627-1636.
-
(2008)
Mol. Biol. Cell.
, vol.19
, pp. 1627-1636
-
-
Singh, M.K.1
Dadke, D.2
Nicolas, E.3
Serebriiskii, I.G.4
Apostolou, S.5
Canutescu, A.6
Egleston, B.L.7
Golemis, E.A.8
-
52
-
-
34147122159
-
In vitro and in vivo synergy of MCP compounds with mitogen-activated protein kinase pathway- and microtubule-targeting inhibitors
-
Skobeleva, N., S. Menon, L. Weber, E.A. Golemis, and V. Khazak. 2007. In vitro and in vivo synergy of MCP compounds with mitogen-activated protein kinase pathway- and microtubule-targeting inhibitors. Mol. Cancer Ther. 6:898-906.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 898-906
-
-
Skobeleva, N.1
Menon, S.2
Weber, L.3
Golemis, E.A.4
Khazak, V.5
-
54
-
-
33746080016
-
PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity
-
Soncini, C., P. Carpinelli, L. Gianellini, D. Fancelli, P. Vianello, L. Rusconi, P. Storici, P. Zugnoni, E. Pesenti, V. Croci, et al. 2006. PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity. Clin. Cancer Res. 12:4080-4089.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 4080-4089
-
-
Soncini, C.1
Carpinelli, P.2
Gianellini, L.3
Fancelli, D.4
Vianello, P.5
Rusconi, L.6
Storici, P.7
Zugnoni, P.8
Pesenti, E.9
Croci, V.10
-
55
-
-
33646155954
-
Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro
-
Streets, A.J., D.J. Moon, M.E. Kane, T. Obara, and A.C. Ong. 2006. Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro. Hum. Mol. Genet. 15:1465-1473.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1465-1473
-
-
Streets, A.J.1
Moon, D.J.2
Kane, M.E.3
Obara, T.4
Ong, A.C.5
-
56
-
-
78649637949
-
Protein kinase D-mediated phosphorylation of polycystin-2 (TRPP2) is essential for its effects on cell growth and calcium channel activity
-
Streets, A.J., A.J. Needham, S.K. Gill, and A.C. Ong. 2010. Protein kinase D-mediated phosphorylation of polycystin-2 (TRPP2) is essential for its effects on cell growth and calcium channel activity. Mol. Biol. Cell. 21:3853-3865.
-
(2010)
Mol. Biol. Cell.
, vol.21
, pp. 3853-3865
-
-
Streets, A.J.1
Needham, A.J.2
Gill, S.K.3
Ong, A.C.4
-
57
-
-
48149104099
-
Src inhibition ameliorates polycystic kidney disease
-
Sweeney, W.E. Jr., R.O. von Vigier, P. Frost, and E.D. Avner. 2008. Src inhibition ameliorates polycystic kidney disease. J. Am. Soc. Nephrol. 19:1331- 1341.
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 1331-1341
-
-
Sweeney Jr., W.E.1
von Vigier, R.O.2
Frost, P.3
Avner, E.D.4
-
58
-
-
0033135640
-
Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast
-
Tanaka, T., M. Kimura, K. Matsunaga, D. Fukada, H. Mori, and Y. Okano. 1999. Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast. Cancer Res. 59:2041-2044.
-
(1999)
Cancer Res
, vol.59
, pp. 2041-2044
-
-
Tanaka, T.1
Kimura, M.2
Matsunaga, K.3
Fukada, D.4
Mori, H.5
Okano, Y.6
-
59
-
-
0034025874
-
Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer
-
Tanner, M.M., S. Grenman, A. Koul, O. Johannsson, P. Meltzer, T. Pejovic, A. Borg, and J.J. Isola. 2000. Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer. Clin. Cancer Res. 6:1833-1839.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1833-1839
-
-
Tanner, M.M.1
Grenman, S.2
Koul, A.3
Johannsson, O.4
Meltzer, P.5
Pejovic, T.6
Borg, A.7
Isola, J.J.8
-
60
-
-
0032213515
-
Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells
-
Tatsuka, M., H. Katayama, T. Ota, T. Tanaka, S. Odashima, F. Suzuki, and Y. Terada. 1998. Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res. 58:4811-4816.
-
(1998)
Cancer Res
, vol.58
, pp. 4811-4816
-
-
Tatsuka, M.1
Katayama, H.2
Ota, T.3
Tanaka, T.4
Odashima, S.5
Suzuki, F.6
Terada, Y.7
-
61
-
-
0347357836
-
Polycystic kidney disease
-
Wilson, P.D. 2004. Polycystic kidney disease. N. Engl. J. Med. 350:151-164.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 151-164
-
-
Wilson, P.D.1
-
62
-
-
69949136621
-
Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis
-
Wong, S.Y., A.D. Seol, P.L. So, A.N. Ermilov, C.K. Bichakjian, E.H. Epstein Jr., A.A. Dlugosz, and J.F. Reiter. 2009. Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat. Med. 15:1055-1061.
-
(2009)
Nat. Med.
, vol.15
, pp. 1055-1061
-
-
Wong, S.Y.1
Seol, A.D.2
So, P.L.3
Ermilov, A.N.4
Bichakjian, C.K.5
Epstein Jr., E.H.6
Dlugosz, A.A.7
Reiter, J.F.8
-
63
-
-
20144373746
-
Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening
-
Wu, J.C., T.Y. Chen, C.T. Yu, S.J. Tsai, J.M. Hsu, M.J. Tang, C.K. Chou, W.J. Lin, C.J. Yuan, and C.Y. Huang. 2005. Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening. J. Biol. Chem. 280:9013-9022.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9013-9022
-
-
Wu, J.C.1
Chen, T.Y.2
Yu, C.T.3
Tsai, S.J.4
Hsu, J.M.5
Tang, M.J.6
Chou, C.K.7
Lin, W.J.8
Yuan, C.J.9
Huang, C.Y.10
-
64
-
-
78649865940
-
VHL inactivation induces HEF1 and Aurora kinase A
-
Xu, J., H. Li, B. Wang, Y. Xu, J. Yang, X. Zhang, S.K. Harten, D. Shukla, P.H. Maxwell, D. Pei, and M.A. Esteban. 2010. VHL inactivation induces HEF1 and Aurora kinase A. J. Am. Soc. Nephrol. 21:2041-2046.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 2041-2046
-
-
Xu, J.1
Li, H.2
Wang, B.3
Xu, Y.4
Yang, J.5
Zhang, X.6
Harten, S.K.7
Shukla, D.8
Maxwell, P.H.9
Pei, D.10
Esteban, M.A.11
-
65
-
-
77953591215
-
The essential role of LIS1, NDEL1 and Aurora-A in polarity formation and microtubule organization during neurogensis
-
Yamada, M., S. Hirotsune, and A. Wynshaw-Boris. 2010. The essential role of LIS1, NDEL1 and Aurora-A in polarity formation and microtubule organization during neurogensis. Cell Adh Migr. 4:180-184.
-
(2010)
Cell Adh Migr
, vol.4
, pp. 180-184
-
-
Yamada, M.1
Hirotsune, S.2
Wynshaw-Boris, A.3
-
66
-
-
9944220985
-
Cre-loxPcontrolled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models
-
Zhang, D., T. Hirota, T. Marumoto, M. Shimizu, N. Kunitoku, T. Sasayama, Y. Arima, L. Feng, M. Suzuki, M. Takeya, and H. Saya. 2004. Cre-loxPcontrolled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models. Oncogene. 23:8720-8730.
-
(2004)
Oncogene
, vol.23
, pp. 8720-8730
-
-
Zhang, D.1
Hirota, T.2
Marumoto, T.3
Shimizu, M.4
Kunitoku, N.5
Sasayama, T.6
Arima, Y.7
Feng, L.8
Suzuki, M.9
Takeya, M.10
Saya, H.11
-
67
-
-
0031714080
-
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
-
Zhou, H., J. Kuang, L. Zhong, W.L. Kuo, J.W. Gray, A. Sahin, B.R. Brinkley, and S. Sen. 1998. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat. Genet. 20:189- 193.
-
(1998)
Nat. Genet.
, vol.20
, pp. 189-193
-
-
Zhou, H.1
Kuang, J.2
Zhong, L.3
Kuo, W.L.4
Gray, J.W.5
Sahin, A.6
Brinkley, B.R.7
Sen, S.8
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