Model equations for the kinetics of covalent irreversible enzyme inhibition and spontaneous reactivation: Esterases and organophosphorus compounds

Critical Reviews in Toxicology

Volumn 39, Issue 5, 2009, Pages 427-448

  Estevez, Jorge ^a   Vilanova, Eugenio ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

Acetylcholinesterase; Aging reaction; Carbamates; Dephosphorylation; Esterases; Inhibition; Kinetic; Model equation; Neuropathy target esterase; Ongoing inhibition; Organophosphorus; Phosphorylation; Reactivation

Indexed keywords

ACETYLCHOLINESTERASE; ESTERASE; NEUROTOXIC ESTERASE; ORGANOPHOSPHORUS COMPOUND; SERINE PEPTIDASE; UNCLASSIFIED DRUG; CHOLINESTERASE REACTIVATOR; ENZYME INHIBITOR;

CARBAMOYLATION; CATALYSIS; COVALENT BOND; DEALKYLATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; HYDROLYSIS; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; PROTEIN CLEAVAGE; PROTEIN DEPHOSPHORYLATION; REACTION TIME; REVIEW; ANIMAL; BIOLOGICAL MODEL; KINETICS; METABOLISM;

ANIMALS; CHOLINESTERASE REACTIVATORS; ENZYME INHIBITORS; ESTERASES; KINETICS; MODELS, BIOLOGICAL; ORGANOPHOSPHORUS COMPOUNDS;

EID: 68849112180     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.1080/10408440802412309     Document Type: Review

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