-
1
-
-
1842283729
-
Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype
-
Regan J.W., Kobilka T.S., Yang-Feng T.L., Caron M.G., Lefkowitz R.J., Kobilka B.K. Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. Proc Natl Acad Sci U S A 1988, 85:6301-6305.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 6301-6305
-
-
Regan, J.W.1
Kobilka, T.S.2
Yang-Feng, T.L.3
Caron, M.G.4
Lefkowitz, R.J.5
Kobilka, B.K.6
-
2
-
-
0030693993
-
Molecular cloning, sequencing and functional study of the promoter region of the human alpha2C4-adrenergic receptor gene
-
Schaak S., Devedjian J.C., Cayla C., Sender Y., Paris H. Molecular cloning, sequencing and functional study of the promoter region of the human alpha2C4-adrenergic receptor gene. Biochem J 1997, 328(Pt 2):431-438.
-
(1997)
Biochem J
, vol.328
, Issue.2 PART
, pp. 431-438
-
-
Schaak, S.1
Devedjian, J.C.2
Cayla, C.3
Sender, Y.4
Paris, H.5
-
3
-
-
84878817295
-
-
Last modified on 2010-06-28
-
Bond RA B.D., Eikenburg D.C., Hieble J.P., Hills R., Minneman K.P., Parra S. "Adrenoceptors: α2C-adrenoceptor.", IUPHAR database (IUPHAR-DB) Last modified on 2010-06-28. http://www.iuphar-db.org/DATABASE/ObjectDisplayForwardαobjectId=27.
-
"Adrenoceptors: α2C-adrenoceptor.", IUPHAR database (IUPHAR-DB)
-
-
Bond, R.A.B.D.1
Eikenburg, D.C.2
Hieble, J.P.3
Hills, R.4
Minneman, K.P.5
Parra, S.6
-
4
-
-
33645902491
-
Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment
-
Small K.M., Schwarb M.R., Glinka C., Theiss C.T., Brown K.M., Seman C.A., Liggett S.B. Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment. Biochemistry 2006, 45:4760-4767.
-
(2006)
Biochemistry
, vol.45
, pp. 4760-4767
-
-
Small, K.M.1
Schwarb, M.R.2
Glinka, C.3
Theiss, C.T.4
Brown, K.M.5
Seman, C.A.6
Liggett, S.B.7
-
5
-
-
0033547241
-
Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission
-
Hein L., Altman J.D., Kobilka B.K. Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission. Nature 1999, 402:181-184.
-
(1999)
Nature
, vol.402
, pp. 181-184
-
-
Hein, L.1
Altman, J.D.2
Kobilka, B.K.3
-
6
-
-
0037027480
-
Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure
-
Brede M., Wiesmann F., Jahns R., Hadamek K., Arnolt C., Neubauer S., Lohse M.J., Hein L. Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure. Circulation 2002, 106:2491-2496.
-
(2002)
Circulation
, vol.106
, pp. 2491-2496
-
-
Brede, M.1
Wiesmann, F.2
Jahns, R.3
Hadamek, K.4
Arnolt, C.5
Neubauer, S.6
Lohse, M.J.7
Hein, L.8
-
7
-
-
0034725616
-
A four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectors
-
Small K.M., Forbes S.L., Rahman F.F., Bridges K.M., Liggett S.B. A four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectors. J Biol Chem 2000, 275:23059-23064.
-
(2000)
J Biol Chem
, vol.275
, pp. 23059-23064
-
-
Small, K.M.1
Forbes, S.L.2
Rahman, F.F.3
Bridges, K.M.4
Liggett, S.B.5
-
8
-
-
0037057235
-
Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure
-
Small K.M., Wagoner L.E., Levin A.M., Kardia S.L., Liggett S.B. Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure. N Engl J Med 2002, 347:1135-1142.
-
(2002)
N Engl J Med
, vol.347
, pp. 1135-1142
-
-
Small, K.M.1
Wagoner, L.E.2
Levin, A.M.3
Kardia, S.L.4
Liggett, S.B.5
-
9
-
-
4444293419
-
Polymorphisms of cardiac presynaptic alpha2C adrenergic receptors: diverse intragenic variability with haplotype-specific functional effects
-
Small K.M., Mialet-Perez J., Seman C.A., Theiss C.T., Brown K.M., Liggett S.B. Polymorphisms of cardiac presynaptic alpha2C adrenergic receptors: diverse intragenic variability with haplotype-specific functional effects. Proc Natl Acad Sci U S A 2004, 101:13020-13025.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13020-13025
-
-
Small, K.M.1
Mialet-Perez, J.2
Seman, C.A.3
Theiss, C.T.4
Brown, K.M.5
Liggett, S.B.6
-
10
-
-
0035815077
-
Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target studies in transgenic mouse models
-
Scheinin M., Sallinen J., Haapalinna A. Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target studies in transgenic mouse models. Life Sci 2001, 68:2277-2285.
-
(2001)
Life Sci
, vol.68
, pp. 2277-2285
-
-
Scheinin, M.1
Sallinen, J.2
Haapalinna, A.3
-
11
-
-
0030610424
-
Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo
-
Lakhlani P.P., MacMillan L.B., Guo T.Z., McCool B.A., Lovinger D.M., Maze M., Limbird L.E. Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo. Proc Natl Acad Sci U S A 1997, 94:9950-9955.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 9950-9955
-
-
Lakhlani, P.P.1
MacMillan, L.B.2
Guo, T.Z.3
McCool, B.A.4
Lovinger, D.M.5
Maze, M.6
Limbird, L.E.7
-
12
-
-
0033035023
-
Abnormal regulation of the sympathetic nervous system in alpha2A-adrenergic receptor knockout mice
-
Altman J.D., Trendelenburg A.U., MacMillan L., Bernstein D., Limbird L., Starke K., Kobilka B.K., Hein L. Abnormal regulation of the sympathetic nervous system in alpha2A-adrenergic receptor knockout mice. Mol Pharmacol 1999, 56:154-161.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 154-161
-
-
Altman, J.D.1
Trendelenburg, A.U.2
MacMillan, L.3
Bernstein, D.4
Limbird, L.5
Starke, K.6
Kobilka, B.K.7
Hein, L.8
-
13
-
-
0034999544
-
Vascular adrenoceptors: an update
-
Guimaraes S., Moura D. Vascular adrenoceptors: an update. Pharmacol Rev 2001, 53:319-356.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 319-356
-
-
Guimaraes, S.1
Moura, D.2
-
14
-
-
0022150448
-
Cooling and alpha 1- and alpha 2-adrenergic responses in cutaneous veins: role of receptor reserve
-
Flavahan N.A., Lindblad L.E., Verbeuren T.J., Shepherd J.T., Vanhoutte P.M. Cooling and alpha 1- and alpha 2-adrenergic responses in cutaneous veins: role of receptor reserve. Am J Physiol 1985, 249:H950-H955.
-
(1985)
Am J Physiol
, vol.249
-
-
Flavahan, N.A.1
Lindblad, L.E.2
Verbeuren, T.J.3
Shepherd, J.T.4
Vanhoutte, P.M.5
-
16
-
-
9144263607
-
Regulation of alpha(2)-adrenoceptors in human vascular smooth muscle cells
-
Chotani M.A., Mitra S., Su B.Y., Flavahan S., Eid A.H., Clark K.R., Montague C.R., Paris H., Handy D.E., Flavahan N.A. Regulation of alpha(2)-adrenoceptors in human vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 2004, 286:H59-H67.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
-
-
Chotani, M.A.1
Mitra, S.2
Su, B.Y.3
Flavahan, S.4
Eid, A.H.5
Clark, K.R.6
Montague, C.R.7
Paris, H.8
Handy, D.E.9
Flavahan, N.A.10
-
17
-
-
0030844448
-
Gene targeting-homing in on alpha 2-adrenoceptor-subtype function
-
MacDonald E., Kobilka B.K., Scheinin M. Gene targeting-homing in on alpha 2-adrenoceptor-subtype function. Trends Pharmacol Sci 1997, 18:211-219.
-
(1997)
Trends Pharmacol Sci
, vol.18
, pp. 211-219
-
-
MacDonald, E.1
Kobilka, B.K.2
Scheinin, M.3
-
18
-
-
0029739504
-
Cardiovascular regulation in mice lacking alpha2-adrenergic receptor subtypes b and c
-
Link R.E., Desai K., Hein L., Stevens M.E., Chruscinski A., Bernstein D., Barsh G.S., Kobilka B.K. Cardiovascular regulation in mice lacking alpha2-adrenergic receptor subtypes b and c. Science 1996, 273:803-805.
-
(1996)
Science
, vol.273
, pp. 803-805
-
-
Link, R.E.1
Desai, K.2
Hein, L.3
Stevens, M.E.4
Chruscinski, A.5
Bernstein, D.6
Barsh, G.S.7
Kobilka, B.K.8
-
19
-
-
0029777474
-
Central hypotensive effects of the alpha2a-adrenergic receptor subtype
-
MacMillan L.B., Hein L., Smith M.S., Piascik M.T., Limbird L.E. Central hypotensive effects of the alpha2a-adrenergic receptor subtype. Science 1996, 273:801-803.
-
(1996)
Science
, vol.273
, pp. 801-803
-
-
MacMillan, L.B.1
Hein, L.2
Smith, M.S.3
Piascik, M.T.4
Limbird, L.E.5
-
20
-
-
0034094741
-
Silent alpha(2C)-adrenergic receptors enable cold-induced vasoconstriction in cutaneous arteries
-
Chotani M.A., Flavahan S., Mitra S., Daunt D., Flavahan N.A. Silent alpha(2C)-adrenergic receptors enable cold-induced vasoconstriction in cutaneous arteries. Am J Physiol Heart Circ Physiol 2000, 278:H1075-H1083.
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.278
-
-
Chotani, M.A.1
Flavahan, S.2
Mitra, S.3
Daunt, D.4
Flavahan, N.A.5
-
21
-
-
0001296648
-
Physical factors of regulation
-
Vascular Smooth Muscle American Physiological Society, Bethesda, MD, S.A. Bohr DF, H.V. Sparks (Eds.)
-
Vanhoutte P. Physical factors of regulation. Handbook of Physiology, Section 2: The Cardiovascular System 1980, vol. II:443-474. Vascular Smooth Muscle American Physiological Society, Bethesda, MD. S.A. Bohr DF, H.V. Sparks (Eds.).
-
(1980)
Handbook of Physiology, Section 2: The Cardiovascular System
, vol.2
, pp. 443-474
-
-
Vanhoutte, P.1
-
22
-
-
34548329506
-
Role of alpha2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice
-
Honda M., Suzuki M., Nakayama K., Ishikawa T. Role of alpha2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice. Br J Pharmacol 2007, 152:91-100.
-
(2007)
Br J Pharmacol
, vol.152
, pp. 91-100
-
-
Honda, M.1
Suzuki, M.2
Nakayama, K.3
Ishikawa, T.4
-
24
-
-
11144316015
-
Distinct cAMP signaling pathways differentially regulate alpha2C-adrenoceptor expression: role in serum induction in human arteriolar smooth muscle cells
-
Chotani M.A., Mitra S., Eid A.H., Han S.A., Flavahan N.A. Distinct cAMP signaling pathways differentially regulate alpha2C-adrenoceptor expression: role in serum induction in human arteriolar smooth muscle cells. Am J Physiol Heart Circ Physiol 2005, 288:H69-H76.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
-
-
Chotani, M.A.1
Mitra, S.2
Eid, A.H.3
Han, S.A.4
Flavahan, N.A.5
-
25
-
-
49849106317
-
Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors
-
Eid A.H., Chotani M.A., Mitra S., Miller T.J., Flavahan N.A. Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors. Am J Physiol Heart Circ Physiol 2008, 295:H266-H272.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Eid, A.H.1
Chotani, M.A.2
Mitra, S.3
Miller, T.J.4
Flavahan, N.A.5
-
26
-
-
0038461990
-
The vasculopathy of Raynaud's phenomenon and scleroderma
-
vi
-
Flavahan N.A., Flavahan S., Mitra S., Chotani M.A. The vasculopathy of Raynaud's phenomenon and scleroderma. Rheum Dis Clin North Am 2003, 29:275-291. vi.
-
(2003)
Rheum Dis Clin North Am
, vol.29
, pp. 275-291
-
-
Flavahan, N.A.1
Flavahan, S.2
Mitra, S.3
Chotani, M.A.4
-
27
-
-
0029847017
-
Distribution of alpha 2C-adrenergic receptor-like immunoreactivity in the rat central nervous system
-
Rosin D.L., Talley E.M., Lee A., Stornetta R.L., Gaylinn B.D., Guyenet P.G., Lynch K.R. Distribution of alpha 2C-adrenergic receptor-like immunoreactivity in the rat central nervous system. J Comp Neurol 1996, 372:135-165.
-
(1996)
J Comp Neurol
, vol.372
, pp. 135-165
-
-
Rosin, D.L.1
Talley, E.M.2
Lee, A.3
Stornetta, R.L.4
Gaylinn, B.D.5
Guyenet, P.G.6
Lynch, K.R.7
-
28
-
-
33747032525
-
Differential targeting and function of alpha2A and alpha2C adrenergic receptor subtypes in cultured sympathetic neurons
-
Brum P.C., Hurt C.M., Shcherbakova O.G., Kobilka B., Angelotti T. Differential targeting and function of alpha2A and alpha2C adrenergic receptor subtypes in cultured sympathetic neurons. Neuropharmacology 2006, 51:397-413.
-
(2006)
Neuropharmacology
, vol.51
, pp. 397-413
-
-
Brum, P.C.1
Hurt, C.M.2
Shcherbakova, O.G.3
Kobilka, B.4
Angelotti, T.5
-
29
-
-
0031978653
-
Alpha 2-adrenergic receptors increase cell migration and decrease F-actin labeling in rat aortic smooth muscle cells
-
Richman J.G., Regan J.W. Alpha 2-adrenergic receptors increase cell migration and decrease F-actin labeling in rat aortic smooth muscle cells. Am J Physiol 1998, 274:C654-C662.
-
(1998)
Am J Physiol
, vol.274
-
-
Richman, J.G.1
Regan, J.W.2
-
30
-
-
77951731676
-
Regulation of G-protein coupled receptor traffic by an evolutionary conserved hydrophobic signal
-
Angelotti T., Daunt D., Shcherbakova O.G., Kobilka B., Hurt C.M. Regulation of G-protein coupled receptor traffic by an evolutionary conserved hydrophobic signal. Traffic 2010, 11:560-578.
-
(2010)
Traffic
, vol.11
, pp. 560-578
-
-
Angelotti, T.1
Daunt, D.2
Shcherbakova, O.G.3
Kobilka, B.4
Hurt, C.M.5
-
31
-
-
0030908655
-
Subtype-specific intracellular trafficking of alpha2-adrenergic receptors
-
Daunt D.A., Hurt C., Hein L., Kallio J., Feng F., Kobilka B.K. Subtype-specific intracellular trafficking of alpha2-adrenergic receptors. Mol Pharmacol 1997, 51:711-720.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 711-720
-
-
Daunt, D.A.1
Hurt, C.2
Hein, L.3
Kallio, J.4
Feng, F.5
Kobilka, B.K.6
-
32
-
-
78650943372
-
Modulation of alpha(2C) adrenergic receptor temperature-sensitive trafficking by HSP90
-
Filipeanu C.M., de Vries R., Danser A.H., Kapusta D.R. Modulation of alpha(2C) adrenergic receptor temperature-sensitive trafficking by HSP90. Biochim Biophys Acta 2011, 1813:346-357.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 346-357
-
-
Filipeanu, C.M.1
de Vries, R.2
Danser, A.H.3
Kapusta, D.R.4
-
33
-
-
0034634587
-
Cell-type specific targeting of the alpha 2c-adrenoceptor. Evidence for the organization of receptor microdomains during neuronal differentiation of PC12 cells
-
Hurt C.M., Feng F.Y., Kobilka B. Cell-type specific targeting of the alpha 2c-adrenoceptor. Evidence for the organization of receptor microdomains during neuronal differentiation of PC12 cells. J Biol Chem 2000, 275:35424-35431.
-
(2000)
J Biol Chem
, vol.275
, pp. 35424-35431
-
-
Hurt, C.M.1
Feng, F.Y.2
Kobilka, B.3
-
34
-
-
33747585593
-
Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors
-
Prinster S.C., Holmqvist T.G., Hall R.A. Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors. J Pharmacol Exp Ther 2006, 318:974-981.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 974-981
-
-
Prinster, S.C.1
Holmqvist, T.G.2
Hall, R.A.3
-
35
-
-
0029670035
-
The three alpha 2-adrenergic receptor subtypes achieve basolateral localization in Madin-Darby canine kidney II cells via different targeting mechanisms
-
Wozniak M., Limbird L.E. The three alpha 2-adrenergic receptor subtypes achieve basolateral localization in Madin-Darby canine kidney II cells via different targeting mechanisms. J Biol Chem 1996, 271:5017-5024.
-
(1996)
J Biol Chem
, vol.271
, pp. 5017-5024
-
-
Wozniak, M.1
Limbird, L.E.2
-
36
-
-
0028365270
-
Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes
-
Kurose H., Lefkowitz R.J. Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes. J Biol Chem 1994, 269:10093-10099.
-
(1994)
J Biol Chem
, vol.269
, pp. 10093-10099
-
-
Kurose, H.1
Lefkowitz, R.J.2
-
37
-
-
0027174523
-
Cell type-dependent variations in the subcellular distribution of alpha-mannosidase I and II
-
Velasco A., Hendricks L., Moremen K.W., Tulsiani D.R., Touster O., Farquhar M.G. Cell type-dependent variations in the subcellular distribution of alpha-mannosidase I and II. J Cell Biol 1993, 122:39-51.
-
(1993)
J Cell Biol
, vol.122
, pp. 39-51
-
-
Velasco, A.1
Hendricks, L.2
Moremen, K.W.3
Tulsiani, D.R.4
Touster, O.5
Farquhar, M.G.6
-
38
-
-
0032714568
-
Importance of glycosidases in mammalian glycoprotein biosynthesis
-
Herscovics A. Importance of glycosidases in mammalian glycoprotein biosynthesis. Biochim Biophys Acta 1999, 1473:96-107.
-
(1999)
Biochim Biophys Acta
, vol.1473
, pp. 96-107
-
-
Herscovics, A.1
-
39
-
-
0035206445
-
Cooling evokes redistribution of alpha2C-adrenoceptors from Golgi to plasma membrane in transfected human embryonic kidney 293 cells
-
Jeyaraj S.C., Chotani M.A., Mitra S., Gregg H.E., Flavahan N.A., Morrison K.J. Cooling evokes redistribution of alpha2C-adrenoceptors from Golgi to plasma membrane in transfected human embryonic kidney 293 cells. Mol Pharmacol 2001, 60:1195-1200.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 1195-1200
-
-
Jeyaraj, S.C.1
Chotani, M.A.2
Mitra, S.3
Gregg, H.E.4
Flavahan, N.A.5
Morrison, K.J.6
-
40
-
-
0030154620
-
Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein
-
Brown C.R., Hong-Brown L.Q., Biwersi J., Verkman A.S., Welch W.J. Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein. Cell Stress Chaperones 1996, 1:117-125.
-
(1996)
Cell Stress Chaperones
, vol.1
, pp. 117-125
-
-
Brown, C.R.1
Hong-Brown, L.Q.2
Biwersi, J.3
Verkman, A.S.4
Welch, W.J.5
-
41
-
-
53849149321
-
Chemical and biological folding contribute to temperature-sensitive DeltaF508 CFTR trafficking
-
Wang X., Koulov A.V., Kellner W.A., Riordan J.R., Balch W.E. Chemical and biological folding contribute to temperature-sensitive DeltaF508 CFTR trafficking. Traffic 2008, 9:1878-1893.
-
(2008)
Traffic
, vol.9
, pp. 1878-1893
-
-
Wang, X.1
Koulov, A.V.2
Kellner, W.A.3
Riordan, J.R.4
Balch, W.E.5
-
42
-
-
34249712933
-
Pharmacological chaperones in nephrogenic diabetes insipidus: possibilities for clinical application
-
Robben J.H., Deen P.M. Pharmacological chaperones in nephrogenic diabetes insipidus: possibilities for clinical application. BioDrugs 2007, 21:157-166.
-
(2007)
BioDrugs
, vol.21
, pp. 157-166
-
-
Robben, J.H.1
Deen, P.M.2
-
43
-
-
67749095283
-
Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists
-
Robben J.H., Kortenoeven M.L., Sze M., Yae C., Milligan G., Oorschot V.M., Klumperman J., Knoers N.V., Deen P.M. Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists. Proc Natl Acad Sci U S A 2009, 106:12195-12200.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12195-12200
-
-
Robben, J.H.1
Kortenoeven, M.L.2
Sze, M.3
Yae, C.4
Milligan, G.5
Oorschot, V.M.6
Klumperman, J.7
Knoers, N.V.8
Deen, P.M.9
-
44
-
-
27844457541
-
Cell-surface targeting of alpha2-adrenergic receptors - inhibition by a transport deficient mutant through dimerization
-
Zhou F., Filipeanu C.M., Duvernay M.T., Wu G. Cell-surface targeting of alpha2-adrenergic receptors - inhibition by a transport deficient mutant through dimerization. Cell Signal 2006, 18:318-327.
-
(2006)
Cell Signal
, vol.18
, pp. 318-327
-
-
Zhou, F.1
Filipeanu, C.M.2
Duvernay, M.T.3
Wu, G.4
-
45
-
-
79959355899
-
Temperature-dependent interactions of alpha2C-adrenergic receptor with molecular chaperones
-
Filipeanu C.M. Temperature-dependent interactions of alpha2C-adrenergic receptor with molecular chaperones. Circulation 2008, 118:s514.
-
(2008)
Circulation
, vol.118
-
-
Filipeanu, C.M.1
-
46
-
-
0028979996
-
Characterization of alpha 2A-adrenergic receptors in GT1 neurosecretory cells
-
Lee A., Talley E., Rosin D.L., Lynch K.R. Characterization of alpha 2A-adrenergic receptors in GT1 neurosecretory cells. Neuroendocrinology 1995, 62:215-225.
-
(1995)
Neuroendocrinology
, vol.62
, pp. 215-225
-
-
Lee, A.1
Talley, E.2
Rosin, D.L.3
Lynch, K.R.4
-
47
-
-
0036606360
-
ER transport signals and trafficking of potassium channels and receptors
-
Ma D., Jan L.Y. ER transport signals and trafficking of potassium channels and receptors. Curr Opin Neurobiol 2002, 12:287-292.
-
(2002)
Curr Opin Neurobiol
, vol.12
, pp. 287-292
-
-
Ma, D.1
Jan, L.Y.2
-
48
-
-
0033710346
-
Molecular basis for K(ATP) assembly: transmembrane interactions mediate association of a K+channel with an ABC transporter
-
Schwappach B., Zerangue N., Jan Y.N., Jan L.Y. Molecular basis for K(ATP) assembly: transmembrane interactions mediate association of a K+channel with an ABC transporter. Neuron 2000, 26:155-167.
-
(2000)
Neuron
, vol.26
, pp. 155-167
-
-
Schwappach, B.1
Zerangue, N.2
Jan, Y.N.3
Jan, L.Y.4
-
49
-
-
33744949447
-
Intracellular trafficking of KA2 kainate receptors mediated by interactions with coatomer protein complex I (COPI) and 14-3-3 chaperone systems
-
Vivithanaporn P., Yan S., Swanson G.T. Intracellular trafficking of KA2 kainate receptors mediated by interactions with coatomer protein complex I (COPI) and 14-3-3 chaperone systems. J Biol Chem 2006, 281:15475-15484.
-
(2006)
J Biol Chem
, vol.281
, pp. 15475-15484
-
-
Vivithanaporn, P.1
Yan, S.2
Swanson, G.T.3
-
50
-
-
0037112329
-
Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals
-
O'Kelly I., Butler M.H., Zilberberg N., Goldstein S.A. Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals. Cell 2002, 111:577-588.
-
(2002)
Cell
, vol.111
, pp. 577-588
-
-
O'Kelly, I.1
Butler, M.H.2
Zilberberg, N.3
Goldstein, S.A.4
-
51
-
-
0342858831
-
Receptor subtype-induced targeting and subtype-specific internalization of human alpha(2)-adrenoceptors in PC12 cells
-
Olli-Lahdesmaki T., Kallio J., Scheinin M. Receptor subtype-induced targeting and subtype-specific internalization of human alpha(2)-adrenoceptors in PC12 cells. J Neurosci 1999, 19:9281-9288.
-
(1999)
J Neurosci
, vol.19
, pp. 9281-9288
-
-
Olli-Lahdesmaki, T.1
Kallio, J.2
Scheinin, M.3
-
52
-
-
0028585884
-
Post-translational modifications distinguish cell surface from Golgi-retained beta 1,4 galactosyltransferase molecules, Golgi localization involves active retention
-
Teasdale R.D., Matheson F., Gleeson P.A. Post-translational modifications distinguish cell surface from Golgi-retained beta 1,4 galactosyltransferase molecules, Golgi localization involves active retention. Glycobiology 1994, 4:917-928.
-
(1994)
Glycobiology
, vol.4
, pp. 917-928
-
-
Teasdale, R.D.1
Matheson, F.2
Gleeson, P.A.3
-
53
-
-
0037446533
-
Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein
-
Wu J., Chalupny N.J., Manley T.J., Riddell S.R., Cosman D., Spies T. Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein. J Immunol 2003, 170:4196-4200.
-
(2003)
J Immunol
, vol.170
, pp. 4196-4200
-
-
Wu, J.1
Chalupny, N.J.2
Manley, T.J.3
Riddell, S.R.4
Cosman, D.5
Spies, T.6
-
54
-
-
0032953879
-
Sequences within the cytoplasmic domain of gp180/carboxypeptidase D mediate localization to the trans-Golgi network
-
Eng F.J., Varlamov O., Fricker L.D. Sequences within the cytoplasmic domain of gp180/carboxypeptidase D mediate localization to the trans-Golgi network. Mol Biol Cell 1999, 10:35-46.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 35-46
-
-
Eng, F.J.1
Varlamov, O.2
Fricker, L.D.3
-
55
-
-
0029029563
-
Trans-Golgi retention of a plasma membrane protein: mutations in the cytoplasmic domain of the asialoglycoprotein receptor subunit H1 result in trans-Golgi retention
-
Wahlberg J.M., Geffen I., Reymond F., Simmen T., Spiess M. Trans-Golgi retention of a plasma membrane protein: mutations in the cytoplasmic domain of the asialoglycoprotein receptor subunit H1 result in trans-Golgi retention. J Cell Biol 1995, 130:285-297.
-
(1995)
J Cell Biol
, vol.130
, pp. 285-297
-
-
Wahlberg, J.M.1
Geffen, I.2
Reymond, F.3
Simmen, T.4
Spiess, M.5
-
56
-
-
0026607683
-
Golgi retention of a trans-Golgi membrane protein, galactosyltransferase, requires cysteine and histidine residues within the membrane-anchoring domain
-
Aoki D., Lee N., Yamaguchi N., Dubois C., Fukuda M.N. Golgi retention of a trans-Golgi membrane protein, galactosyltransferase, requires cysteine and histidine residues within the membrane-anchoring domain. Proc Natl Acad Sci U S A 1992, 89:4319-4323.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 4319-4323
-
-
Aoki, D.1
Lee, N.2
Yamaguchi, N.3
Dubois, C.4
Fukuda, M.N.5
-
57
-
-
0033937217
-
Trafficking of varicella-zoster virus glycoprotein gI: T(338)-dependent retention in the trans-Golgi network, secretion, and mannose 6-phosphate-inhibitable uptake of the ectodomain
-
Wang Z.H., Gershon M.D., Lungu O., Zhu Z., Gershon A.A. Trafficking of varicella-zoster virus glycoprotein gI: T(338)-dependent retention in the trans-Golgi network, secretion, and mannose 6-phosphate-inhibitable uptake of the ectodomain. J Virol 2000, 74:6600-6613.
-
(2000)
J Virol
, vol.74
, pp. 6600-6613
-
-
Wang, Z.H.1
Gershon, M.D.2
Lungu, O.3
Zhu, Z.4
Gershon, A.A.5
-
58
-
-
59449084113
-
Apical targeting and Golgi retention signals reside within a 9-amino acid sequence in the copper-ATPase, ATP7B
-
Braiterman L., Nyasae L., Guo Y., Bustos R., Lutsenko S., Hubbard A. Apical targeting and Golgi retention signals reside within a 9-amino acid sequence in the copper-ATPase, ATP7B. Am J Physiol Gastrointest Liver Physiol 2009, 296:G433-G444.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
-
-
Braiterman, L.1
Nyasae, L.2
Guo, Y.3
Bustos, R.4
Lutsenko, S.5
Hubbard, A.6
-
59
-
-
21644490277
-
Reactive oxygen species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries
-
Bailey S.R., Mitra S., Flavahan S., Flavahan N.A. Reactive oxygen species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries. Am J Physiol Heart Circ Physiol 2005, 289:H243-H250.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Bailey, S.R.1
Mitra, S.2
Flavahan, S.3
Flavahan, N.A.4
-
60
-
-
2642569161
-
Rho kinase mediates cold-induced constriction of cutaneous arteries: role of alpha2C-adrenoceptor translocation
-
Bailey S.R., Eid A.H., Mitra S., Flavahan S., Flavahan N.A. Rho kinase mediates cold-induced constriction of cutaneous arteries: role of alpha2C-adrenoceptor translocation. Circ Res 2004, 94:1367-1374.
-
(2004)
Circ Res
, vol.94
, pp. 1367-1374
-
-
Bailey, S.R.1
Eid, A.H.2
Mitra, S.3
Flavahan, S.4
Flavahan, N.A.5
-
61
-
-
0028053488
-
Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor
-
Hein L., Ishii K., Coughlin S.R., Kobilka B.K. Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor. J Biol Chem 1994, 269:27719-27726.
-
(1994)
J Biol Chem
, vol.269
, pp. 27719-27726
-
-
Hein, L.1
Ishii, K.2
Coughlin, S.R.3
Kobilka, B.K.4
-
62
-
-
0028929733
-
Direct measurement of trans-Golgi pH in living cells and regulation by second messengers
-
Seksek O., Biwersi J., Verkman A.S. Direct measurement of trans-Golgi pH in living cells and regulation by second messengers. J Biol Chem 1995, 270:4967-4970.
-
(1995)
J Biol Chem
, vol.270
, pp. 4967-4970
-
-
Seksek, O.1
Biwersi, J.2
Verkman, A.S.3
-
63
-
-
0035325257
-
Peptide-based targeting of fluorophores to organelles in living cells
-
Pap E.H., Dansen T.B., van Summeren R., Wirtz K.W. Peptide-based targeting of fluorophores to organelles in living cells. Exp Cell Res 2001, 265:288-293.
-
(2001)
Exp Cell Res
, vol.265
, pp. 288-293
-
-
Pap, E.H.1
Dansen, T.B.2
van Summeren, R.3
Wirtz, K.W.4
-
64
-
-
0035041875
-
Agonist-dependent delivery of M(2) muscarinic acetylcholine receptors to the cell surface after pertussis toxin treatment
-
Roseberry A.G., Bunemann M., Elavunkal J., Hosey M.M. Agonist-dependent delivery of M(2) muscarinic acetylcholine receptors to the cell surface after pertussis toxin treatment. Mol Pharmacol 2001, 59:1256-1268.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 1256-1268
-
-
Roseberry, A.G.1
Bunemann, M.2
Elavunkal, J.3
Hosey, M.M.4
-
65
-
-
59849113480
-
VEGFR1 receptor tyrosine kinase localization to the Golgi apparatus is calcium-dependent
-
Mittar S., Ulyatt C., Howell G.J., Bruns A.F., Zachary I., Walker J.H., Ponnambalam S. VEGFR1 receptor tyrosine kinase localization to the Golgi apparatus is calcium-dependent. Exp Cell Res 2009, 315:877-889.
-
(2009)
Exp Cell Res
, vol.315
, pp. 877-889
-
-
Mittar, S.1
Ulyatt, C.2
Howell, G.J.3
Bruns, A.F.4
Zachary, I.5
Walker, J.H.6
Ponnambalam, S.7
-
66
-
-
0037444542
-
Neurotrophin-regulated sorting of opioid receptors in the biosynthetic pathway of neurosecretory cells
-
Kim K.A., von Zastrow M. Neurotrophin-regulated sorting of opioid receptors in the biosynthetic pathway of neurosecretory cells. J Neurosci 2003, 23:2075-2085.
-
(2003)
J Neurosci
, vol.23
, pp. 2075-2085
-
-
Kim, K.A.1
von Zastrow, M.2
-
67
-
-
0029719789
-
-
Desensitization of G protein-coupled receptors, Recent Prog Horm Res 51 (1996) 319-351; discussion 352-313.
-
N.J. Freedman, R.J. Lefkowitz, Desensitization of G protein-coupled receptors, Recent Prog Horm Res 51 (1996) 319-351; discussion 352-313.
-
-
-
Freedman, N.J.1
Lefkowitz, R.J.2
-
68
-
-
0001571429
-
The role of alpha2-adrenoceptors as cutaneous thermosensors
-
Flavahan N.A. The role of alpha2-adrenoceptors as cutaneous thermosensors. News in Physiological Sciences 1991, 6:251-255.
-
(1991)
News in Physiological Sciences
, vol.6
, pp. 251-255
-
-
Flavahan, N.A.1
-
69
-
-
0034999544
-
Vascular adrenoceptors: an update
-
Guimaraes S., Moura D. Vascular adrenoceptors: an update. Pharmacol Rev 2001, 53:319-356.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 319-356
-
-
Guimaraes, S.1
Moura, D.2
-
71
-
-
0024262633
-
Alpha-Adrenoceptors and cold-induced vasoconstriction in human finger skin
-
Ekenvall L., Lindblad L.E., Norbeck O., Etzell B.M. Alpha-Adrenoceptors and cold-induced vasoconstriction in human finger skin. Am J Physiol 1988, 255:H1000-H1003.
-
(1988)
Am J Physiol
, vol.255
-
-
Ekenvall, L.1
Lindblad, L.E.2
Norbeck, O.3
Etzell, B.M.4
-
72
-
-
0023710417
-
Effect of local tissue cooling on microvascular smooth muscle and postjunctional alpha 2-adrenoceptors
-
Faber J.E. Effect of local tissue cooling on microvascular smooth muscle and postjunctional alpha 2-adrenoceptors. Am J Physiol 1988, 255:H121-H130.
-
(1988)
Am J Physiol
, vol.255
-
-
Faber, J.E.1
-
73
-
-
0025874836
-
Cooling augments alpha 2-adrenoceptor-mediated contractions in rat tail artery
-
Harker C.T., Ousley P.J., Bowman C.J., Porter J.M. Cooling augments alpha 2-adrenoceptor-mediated contractions in rat tail artery. Am J Physiol 1991, 260:H1166-H1171.
-
(1991)
Am J Physiol
, vol.260
-
-
Harker, C.T.1
Ousley, P.J.2
Bowman, C.J.3
Porter, J.M.4
-
74
-
-
0025331092
-
The effects of cooling on human saphenous vein reactivity to adrenergic agonists
-
Harker C.T., Ousley P.J., Harris E.J., Edwards J.M., Taylor L.M., Porter J.M. The effects of cooling on human saphenous vein reactivity to adrenergic agonists. J Vasc Surg 1990, 12:45-49.
-
(1990)
J Vasc Surg
, vol.12
, pp. 45-49
-
-
Harker, C.T.1
Ousley, P.J.2
Harris, E.J.3
Edwards, J.M.4
Taylor, L.M.5
Porter, J.M.6
-
75
-
-
0029128890
-
Blockade of vasospastic attacks by alpha 2-adrenergic but not alpha 1- adrenergic antagonists in idiopathic Raynaud's disease
-
Freedman R.R., Baer R.P., Mayes M.D. Blockade of vasospastic attacks by alpha 2-adrenergic but not alpha 1- adrenergic antagonists in idiopathic Raynaud's disease. Circulation 1995, 92:1448-1451.
-
(1995)
Circulation
, vol.92
, pp. 1448-1451
-
-
Freedman, R.R.1
Baer, R.P.2
Mayes, M.D.3
-
76
-
-
85008067124
-
Alpha 2-adrenoceptor inhibition in patients with vibration white fingers
-
Lindblad L.E., Ekenvall L. Alpha 2-adrenoceptor inhibition in patients with vibration white fingers. Kurume Med J 1990, 37(Suppl):S95-S99.
-
(1990)
Kurume Med J
, vol.37
, Issue.SUPPL.
-
-
Lindblad, L.E.1
Ekenvall, L.2
-
77
-
-
15744391937
-
Phenylpropanolamine constricts mouse and human blood vessels by preferentially activating alpha2-adrenoceptors
-
Flavahan N.A. Phenylpropanolamine constricts mouse and human blood vessels by preferentially activating alpha2-adrenoceptors. J Pharmacol Exp Ther 2005, 313:432-439.
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 432-439
-
-
Flavahan, N.A.1
-
78
-
-
0021129748
-
Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein
-
Flavahan N.A., Rimele T.J., Cooke J.P., Vanhoutte P.M. Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein. J Pharmacol Exp Ther 1984, 230:699-705.
-
(1984)
J Pharmacol Exp Ther
, vol.230
, pp. 699-705
-
-
Flavahan, N.A.1
Rimele, T.J.2
Cooke, J.P.3
Vanhoutte, P.M.4
-
79
-
-
0022510759
-
Alpha-1 and alpha-2 adrenoceptor: response coupling in canine saphenous and femoral veins
-
Flavahan N.A., Vanhoutte P.M. Alpha-1 and alpha-2 adrenoceptor: response coupling in canine saphenous and femoral veins. J Pharmacol Exp Ther 1986, 238:131-138.
-
(1986)
J Pharmacol Exp Ther
, vol.238
, pp. 131-138
-
-
Flavahan, N.A.1
Vanhoutte, P.M.2
-
80
-
-
0025757312
-
Influence of angiotensin II on the alpha-adrenoceptors involved in mediating the response to sympathetic nerve stimulation in the rabbit isolated distal saphenous artery
-
Dunn W.R., McGrath J.C., Wilson V.G. Influence of angiotensin II on the alpha-adrenoceptors involved in mediating the response to sympathetic nerve stimulation in the rabbit isolated distal saphenous artery. Br J Pharmacol 1991, 102:10-12.
-
(1991)
Br J Pharmacol
, vol.102
, pp. 10-12
-
-
Dunn, W.R.1
McGrath, J.C.2
Wilson, V.G.3
-
81
-
-
0024322353
-
Evidence for prazosin-resistant, rauwolscine-sensitive alpha-adrenoceptors mediating contractions in the isolated vascular bed of the rat tail
-
Templeton A.G., Macmillan J., McGrath J.C., Storey N.D., Wilson V.G. Evidence for prazosin-resistant, rauwolscine-sensitive alpha-adrenoceptors mediating contractions in the isolated vascular bed of the rat tail. Br J Pharmacol 1989, 97:563-571.
-
(1989)
Br J Pharmacol
, vol.97
, pp. 563-571
-
-
Templeton, A.G.1
Macmillan, J.2
McGrath, J.C.3
Storey, N.D.4
Wilson, V.G.5
-
82
-
-
0025653174
-
Vasoconstrictor responses to the alpha 2-adrenoceptor agonist UK14304 during responses to noradrenaline, phenylephrine, serotonin and vasopressin of the rat tail artery
-
Xiao X.H., Rand M.J. Vasoconstrictor responses to the alpha 2-adrenoceptor agonist UK14304 during responses to noradrenaline, phenylephrine, serotonin and vasopressin of the rat tail artery. Arch Int Pharmacodyn Ther 1990, 308:63-75.
-
(1990)
Arch Int Pharmacodyn Ther
, vol.308
, pp. 63-75
-
-
Xiao, X.H.1
Rand, M.J.2
-
83
-
-
78649980833
-
Postjunctional alpha2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity
-
Jantschak F., Popp A.M., Hofmann R.A., Villalon C.M., Centurion D., Pertz H.H. Postjunctional alpha2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity. Naunyn Schmiedebergs Arch Pharmacol 2010, 382:487-497.
-
(2010)
Naunyn Schmiedebergs Arch Pharmacol
, vol.382
, pp. 487-497
-
-
Jantschak, F.1
Popp, A.M.2
Hofmann, R.A.3
Villalon, C.M.4
Centurion, D.5
Pertz, H.H.6
-
84
-
-
59149095688
-
Increased oxidant activity mediates vascular dysfunction in vibration injury
-
Hughes J.M., Wirth O., Krajnak K., Miller R., Flavahan S., Berkowitz D.E., Welcome D., Flavahan N.A. Increased oxidant activity mediates vascular dysfunction in vibration injury. J Pharmacol Exp Ther 2009, 328:223-230.
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 223-230
-
-
Hughes, J.M.1
Wirth, O.2
Krajnak, K.3
Miller, R.4
Flavahan, S.5
Berkowitz, D.E.6
Welcome, D.7
Flavahan, N.A.8
-
85
-
-
0026781952
-
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
-
Denning G.M., Anderson M.P., Amara J.F., Marshall J., Smith A.E., Welsh M.J. Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive. Nature 1992, 358:761-764.
-
(1992)
Nature
, vol.358
, pp. 761-764
-
-
Denning, G.M.1
Anderson, M.P.2
Amara, J.F.3
Marshall, J.4
Smith, A.E.5
Welsh, M.J.6
-
86
-
-
65449136273
-
A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature
-
Delaunay J.L., Durand-Schneider A.M., Delautier D., Rada A., Gautherot J., Jacquemin E., Ait-Slimane T., Maurice M. A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature. Hepatology 2009, 49:1218-1227.
-
(2009)
Hepatology
, vol.49
, pp. 1218-1227
-
-
Delaunay, J.L.1
Durand-Schneider, A.M.2
Delautier, D.3
Rada, A.4
Gautherot, J.5
Jacquemin, E.6
Ait-Slimane, T.7
Maurice, M.8
-
87
-
-
30044447860
-
Heterodimers of alpha1B- and alpha1D-adrenergic receptors form a single functional entity
-
Hague C., Lee S.E., Chen Z., Prinster S.C., Hall R.A., Minneman K.P. Heterodimers of alpha1B- and alpha1D-adrenergic receptors form a single functional entity. Mol Pharmacol 2006, 69:45-55.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 45-55
-
-
Hague, C.1
Lee, S.E.2
Chen, Z.3
Prinster, S.C.4
Hall, R.A.5
Minneman, K.P.6
-
88
-
-
23944501304
-
Heterodimerization of g protein-coupled receptors: specificity and functional significance
-
Prinster S.C., Hague C., Hall R.A. Heterodimerization of g protein-coupled receptors: specificity and functional significance. Pharmacol Rev 2005, 57:289-298.
-
(2005)
Pharmacol Rev
, vol.57
, pp. 289-298
-
-
Prinster, S.C.1
Hague, C.2
Hall, R.A.3
-
89
-
-
15744405558
-
Heterodimerization with beta2-adrenergic receptors promotes surface expression and functional activity of alpha1D-adrenergic receptors
-
Uberti M.A., Hague C., Oller H., Minneman K.P., Hall R.A. Heterodimerization with beta2-adrenergic receptors promotes surface expression and functional activity of alpha1D-adrenergic receptors. J Pharmacol Exp Ther 2005, 313:16-23.
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 16-23
-
-
Uberti, M.A.1
Hague, C.2
Oller, H.3
Minneman, K.P.4
Hall, R.A.5
-
90
-
-
33750842131
-
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
-
Wang X., Venable J., LaPointe P., Hutt D.M., Koulov A.V., Coppinger J., Gurkan C., Kellner W., Matteson J., Plutner H., Riordan J.R., Kelly J.W., Yates J.R., Balch W.E. Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Cell 2006, 127:803-815.
-
(2006)
Cell
, vol.127
, pp. 803-815
-
-
Wang, X.1
Venable, J.2
LaPointe, P.3
Hutt, D.M.4
Koulov, A.V.5
Coppinger, J.6
Gurkan, C.7
Kellner, W.8
Matteson, J.9
Plutner, H.10
Riordan, J.R.11
Kelly, J.W.12
Yates, J.R.13
Balch, W.E.14
-
91
-
-
51349113842
-
Chaperone displacement from mutant cystic fibrosis transmembrane conductance regulator restores its function in human airway epithelia
-
Sun F., Mi Z., Condliffe S.B., Bertrand C.A., Gong X., Lu X., Zhang R., Latoche J.D., Pilewski J.M., Robbins P.D., Frizzell R.A. Chaperone displacement from mutant cystic fibrosis transmembrane conductance regulator restores its function in human airway epithelia. FASEB J 2008, 22:3255-3263.
-
(2008)
FASEB J
, vol.22
, pp. 3255-3263
-
-
Sun, F.1
Mi, Z.2
Condliffe, S.B.3
Bertrand, C.A.4
Gong, X.5
Lu, X.6
Zhang, R.7
Latoche, J.D.8
Pilewski, J.M.9
Robbins, P.D.10
Frizzell, R.A.11
-
92
-
-
33750700517
-
Increased vascular responsiveness to alpha 2-adrenergic stimulation during NOS inhibition-induced hypertension
-
Kanagy N.L. Increased vascular responsiveness to alpha 2-adrenergic stimulation during NOS inhibition-induced hypertension. Am J Physiol 1997, 273:H2756-H2764.
-
(1997)
Am J Physiol
, vol.273
-
-
Kanagy, N.L.1
-
93
-
-
1342344805
-
Membrane trafficking of G protein-coupled receptors
-
Tan C.M., Brady A.E., Nickols H.H., Wang Q., Limbird L.E. Membrane trafficking of G protein-coupled receptors. Annu Rev Pharmacol Toxicol 2004, 44:559-609.
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 559-609
-
-
Tan, C.M.1
Brady, A.E.2
Nickols, H.H.3
Wang, Q.4
Limbird, L.E.5
-
94
-
-
77952509095
-
Signaling by internalized G-protein-coupled receptors
-
Calebiro D., Nikolaev V.O., Persani L., Lohse M.J. Signaling by internalized G-protein-coupled receptors. Trends Pharmacol Sci 2010, 31:221-228.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 221-228
-
-
Calebiro, D.1
Nikolaev, V.O.2
Persani, L.3
Lohse, M.J.4
-
95
-
-
23044515099
-
Functions and mechanisms of retrograde neurotrophin signalling
-
Zweifel L.S., Kuruvilla R., Ginty D.D. Functions and mechanisms of retrograde neurotrophin signalling. Nat Rev Neurosci 2005, 6:615-625.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 615-625
-
-
Zweifel, L.S.1
Kuruvilla, R.2
Ginty, D.D.3
-
96
-
-
33749054116
-
G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigm
-
Gobeil F., Fortier A., Zhu T., Bossolasco M., Leduc M., Grandbois M., Heveker N., Bkaily G., Chemtob S., Barbaz D. G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigm. Can J Physiol Pharmacol 2006, 84:287-297.
-
(2006)
Can J Physiol Pharmacol
, vol.84
, pp. 287-297
-
-
Gobeil, F.1
Fortier, A.2
Zhu, T.3
Bossolasco, M.4
Leduc, M.5
Grandbois, M.6
Heveker, N.7
Bkaily, G.8
Chemtob, S.9
Barbaz, D.10
-
97
-
-
77957829687
-
Nuclear localization of vasoactive intestinal peptide (VIP) receptors in human breast cancer
-
Valdehita A., Bajo A.M., Fernandez-Martinez A.B., Arenas M.I., Vacas E., Valenzuela P., Ruiz-Villaespesa A., Prieto J.C., Carmena M.J. Nuclear localization of vasoactive intestinal peptide (VIP) receptors in human breast cancer. Peptides 2010, 31:2035-2045.
-
(2010)
Peptides
, vol.31
, pp. 2035-2045
-
-
Valdehita, A.1
Bajo, A.M.2
Fernandez-Martinez, A.B.3
Arenas, M.I.4
Vacas, E.5
Valenzuela, P.6
Ruiz-Villaespesa, A.7
Prieto, J.C.8
Carmena, M.J.9
-
98
-
-
78650654452
-
CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network
-
Escola J.M., Kuenzi G., Gaertner H., Foti M., Hartley O. CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network. J Biol Chem 2010, 285:41772-41780.
-
(2010)
J Biol Chem
, vol.285
, pp. 41772-41780
-
-
Escola, J.M.1
Kuenzi, G.2
Gaertner, H.3
Foti, M.4
Hartley, O.5
-
99
-
-
43749096330
-
Dynamics of somatostatin type 2A receptor cargoes in living hippocampal neurons
-
Lelouvier B., Tamagno G., Kaindl A.M., Roland A., Lelievre V., Le Verche V., Loudes C., Gressens P., Faivre-Baumann A., Lenkei Z., Dournaud P. Dynamics of somatostatin type 2A receptor cargoes in living hippocampal neurons. J Neurosci 2008, 28:4336-4349.
-
(2008)
J Neurosci
, vol.28
, pp. 4336-4349
-
-
Lelouvier, B.1
Tamagno, G.2
Kaindl, A.M.3
Roland, A.4
Lelievre, V.5
Le Verche, V.6
Loudes, C.7
Gressens, P.8
Faivre-Baumann, A.9
Lenkei, Z.10
Dournaud, P.11
-
100
-
-
0030013246
-
G protein-coupled receptor kinase specificity for phosphorylation and desensitization of alpha2-adrenergic receptor subtypes
-
Jewell-Motz E.A., Liggett S.B. G protein-coupled receptor kinase specificity for phosphorylation and desensitization of alpha2-adrenergic receptor subtypes. J Biol Chem 1996, 271:18082-18087.
-
(1996)
J Biol Chem
, vol.271
, pp. 18082-18087
-
-
Jewell-Motz, E.A.1
Liggett, S.B.2
-
101
-
-
0027174770
-
Functional alpha 2-adrenergic receptor-Gs coupling undergoes agonist-promoted desensitization in a subtype-selective manner
-
Eason M.G., Liggett S.B. Functional alpha 2-adrenergic receptor-Gs coupling undergoes agonist-promoted desensitization in a subtype-selective manner. Biochem Biophys Res Commun 1993, 193:318-323.
-
(1993)
Biochem Biophys Res Commun
, vol.193
, pp. 318-323
-
-
Eason, M.G.1
Liggett, S.B.2
-
102
-
-
0026469352
-
Subtype-selective desensitization of alpha 2-adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of alpha 2C10, alpha 2C4, and alpha 2C2
-
Eason M.G., Liggett S.B. Subtype-selective desensitization of alpha 2-adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of alpha 2C10, alpha 2C4, and alpha 2C2. J Biol Chem 1992, 267:25473-25479.
-
(1992)
J Biol Chem
, vol.267
, pp. 25473-25479
-
-
Eason, M.G.1
Liggett, S.B.2
-
103
-
-
33846234212
-
Signalling complexes associated with adenylyl cyclase II are assembled during their biosynthesis
-
Dupre D.J., Baragli A., Rebois R.V., Ethier N., Hebert T.E. Signalling complexes associated with adenylyl cyclase II are assembled during their biosynthesis. Cell Signal 2007, 19:481-489.
-
(2007)
Cell Signal
, vol.19
, pp. 481-489
-
-
Dupre, D.J.1
Baragli, A.2
Rebois, R.V.3
Ethier, N.4
Hebert, T.E.5
-
104
-
-
33845926059
-
Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking
-
Dupre D.J., Robitaille M., Ethier N., Villeneuve L.R., Mamarbachi A.M., Hebert T.E. Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking. J Biol Chem 2006, 281:34561-34573.
-
(2006)
J Biol Chem
, vol.281
, pp. 34561-34573
-
-
Dupre, D.J.1
Robitaille, M.2
Ethier, N.3
Villeneuve, L.R.4
Mamarbachi, A.M.5
Hebert, T.E.6
-
105
-
-
34547206822
-
Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells
-
Joshi M.S., Ferguson T.B., Johnson F.K., Johnson R.A., Parthasarathy S., Lancaster J.R. Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells. Proc Natl Acad Sci U S A 2007, 104:9982-9987.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 9982-9987
-
-
Joshi, M.S.1
Ferguson, T.B.2
Johnson, F.K.3
Johnson, R.A.4
Parthasarathy, S.5
Lancaster, J.R.6
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