Chaperone displacement from mutant cystic fibrosis transmembrane conductance regulator restores its function in human airway epithelia

FASEB Journal

Volumn 22, Issue 9, 2008, Pages 3255-3263

  Sun, Fei ^a   Mi, Zhibao ^a   Condliffe, Steven B ^a,b   Bertrand, Carol A ^a   Gong, Xiaoyan ^a,c   Lu, Xiaoli ^a   Zhang, Ruilin ^a   Latoche, Joseph D ^a   Pilewski, Joseph M ^a   Robbins, Paul D ^a   Frizzell, Raymond A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aha1; CFTR; PTD; Rescue

Indexed keywords

ANION; ANION CHANNEL; CHAPERONE; CYCLIC AMP; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; PHENYLALANINE; PROTEASOME; TRANSMEMBRANE CONDUCTANCE REGULATOR; UBIQUITIN;

ARTICLE; CELL ISOLATION; CYSTIC FIBROSIS; DOSE RESPONSE; ENDOPLASMIC RETICULUM; EPITHELIUM CELL; GENE MUTATION; HOMOZYGOSITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; RESPIRATORY MUCOSA; TRANSDUCTION, GENETIC;

EID: 51349113842     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-105338     Document Type: Article

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