Sequences within the cytoplasmic domain of Gp180/carboxypeptidase D mediate localization to the trans-Golgi network

Molecular Biology of the Cell

Volumn 10, Issue 1, 1999, Pages 35-46

  Eng, Francis J ^a   Varlamov, Oleg ^a   Fricker, Lloyd D ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE D; GLYCOPROTEIN; MEMBRANE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CELL TRANSPORT; DELETION MUTANT; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TRANSPORT;

ANAS SP.; ANIMALIA; DUCK HEPATITIS B VIRUS; HEPATITIS B VIRUS; MAMMALIA;

EID: 0032953879     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.10.1.35     Document Type: Article

References (39)

1. Bock, J.B., Klumperman, J., Davanger, S., and Scheller, R.H. (1997). Syntaxin 6 functions in trans-Golgi network vesicle trafficking. Mol. Biol. Cell 8, 1261-1271.
2. Bos, K., Wraight, C., and Stanley, K.K. (1993). TGN38 is maintained in the trans-Golgi network by a tyrosine-containing motif in the cytoplasmic domain. EMBO J. 12, 2219-2228.
3. Bosshart, H., Humphrey, J., Deignan, E., Davidson, J., Drazba, J., Yuan, L., Oorschot, V., Peters, P.J., and Bonifacino, J.S. (1994). The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system. J. Cell Biol. 126, 1157-1166.
4. Breiner, K.M., Urban, S., and Schaller, H. (1998). Carboxypeptidase D (gp180), a Golgi-resident protein, functions in the attachment and entry of avian hepatitis B virus. J. Virol. 72, 8098-8104.
5. Davis, L.G., Dibner, M.D., and Battey, J.F. (1986). Basic Methods in Molecular Biology, Amsterdam: Elsevier.
6. Dittie, A.S., Thomas, L., Thomas, G., and Tooze, S.A. (1997). Interaction of furin in immature secretory granules from neuroendocrine cells with the AP-1 adaptor complex is modulated by casein kinase II phosphorylation. EMBO J. 16, 4859-4870.
7. Eng, F.J., Novikova, E.G., Kuroki, K., Ganem, D., and Fricker, L.D. (1998). gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity. J. Biol. Chem. 273, 8382-8388.
8. Feng, Y., Broder, C.C., Kennedy, P.E., and Berger, E.A. (1996). HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G-protein-coupled receptor. Science 272, 872-877.
9. Fricker L.D. (1988). Carboxypeptidase E. Annu. Rev. Physiol. 50, 309-321.
10. Fricker L.D. (1991). Peptide processing exopeptidases: amino-and carboxypeptidases involved with peptide biosynthesis. In: Peptide Biosynthesis and Processing, ed. L.D. Fricker, Boca Raton: CRC Press, 199-230.
11. Fujiwara, T., Oda, K., Yokota, S., Takatsuki, A., and Ikehara, Y. (1988). Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J. Biol. Chem. 263, 18545-18552.
12. Fukuda, M. (1991). Lysosomal membrane glycoproteins. J. Biol. Chem. 266, 21327-21330.
13. Ganem, D., and Varmus, H.E. (1987). The molecular biology of the hepatitis B viruses. Annu. Rev. Biochem. 56, 651-694.
14. Humphrey, J.S., Peters, P.J., Yuan, L.C., and Bonifacino, J.S. (1993). Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence. J. Cell Biol. 120, 1123-1135.
15. Jones, B.G., Thomas, L., Molloy, S.S., Thulin, C.D., Fry, M.D., Walsh, K.A., and Thomas, G. (1995). Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail. EMBO J. 14, 5869-5883.
16. Kock, J., Borst, E.M., and Schlicht, H.J. (1996). Uptake of duck hepatitis B virus into hepatocytes occurs by endocytosis but does not require passage of the virus through an acidic intracellular compartment. J. Virol. 70, 5827-5831.
17. Kuroki, K., Cheung, R., Marion, P.L., and Ganem, D. (1994). A cell surface protein that binds avian hepatitis B virus particles. J. Virol. 68, 2091-2096.
18. Kuroki, K., Eng, F., Ishikawa, T., Turck, C., Harada, F., and Ganem, D. (1995). gp180, a host cell glycoprotein that binds duck hepatitis B virus particles, is encoded by a member of the carboxypeptidase gene family. J. Biol. Chem. 270, 15022-15028.
19. Lippincott-Schwartz, J., Yuan, L.C., Bonifacino, J.S., and Klausner, R.D. (1989). Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell 56, 801-813.
20. Luzio, J.P., Brake, B., Banting, G., Howell, K.E., Braghetta, P., and Stanley, K.K. (1990). Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38). Biochem. J. 270, 97-102.
21. Marks, M.S., Ohno, H., Kirchhausen, T., and Bonifacino, J.S. (1997). Protein sorting by tyrosine-based signals: adapting to the Ys and wherefores. Trends Cell Biol. 7, 124-128.
22. Matsuuchi, L., and Kelly, R.B. (1991). Constitutive and basal secretion from the endocrine cell line, AtT-20. J. Cell Biol. 112, 843-852.
23. Milgram, S.L., Mains, R.E., and Eipper, B.A. (1996). Identification of routing determinants in the cytoplasmic domain of a secretory granule-associated integral membrane protein. J. Biol. Chem. 271, 17526-17535.
24. Molloy, S.S., Thomas, L., VanSlyke, J.K., Stenberg, P.E., and Thomas, G. (1994). Intracellular trafficking and activation of the furin pro-protein convertase: localization to the TGN and recycling from the cell surface. EMBO J. 13, 18-23.
25. Naggert, J.K., Fricker, L.D., Varlamov, O, Nishina, P.M., Rouille, Y., Steiner, D.F., Carroll, R.J., Paigen, B.J., and Leiter, E.H. (1995). Hyperproinsulinemia in obese fat/fat mice associated with a point mutation in the carboxypeptidase E gene and reduced carboxypeptidase E activity in the pancreatic islets. Nat. Genet. 10, 135-142.
26. Reaves, B., and Banting, G. (1992). Perturbation of the morphology of the trans-Golgi network following brefeldin A treatment: redistribution of a TGN-specific integral membrane protein, TGN38. J. Cell Biol. 116, 85-94.
27. Sandoval, I.V., and Bakke, O. (1994). Targeting of membrane proteins to endosomes and lysosomes. Trends Cell Biol. 4, 292-297.
28. Schafer, W., Stroh, A., Berghofer, S., Seiler, J., Vey, M., Kruse, M.L., Kern, H.F., Klenk, H.D., and Garten, W. (1995). Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin. EMBO J. 14, 2424-2435.
29. Settle, S.H.J., Green, M.M., and Burtis, K.C. (1995). The silver gene of Drosophila melanogaster encodes multiple carboxypeptidases similar to mammalian prohormone-processing enzymes. Proc. Natl. Acad. Sci. USA 92, 9470-9474.
30. Song, L., and Fricker, L.D. (1995). Purification and characterization of carboxypeptidase D, a novel carboxypeptidase E-like enzyme, from bovine pituitary. J. Biol. Chem. 270, 25007-25013.
31. Song, L., and Fricker, L.D. (1996). Tissue distribution and characterization of soluble and membrane-bound forms of metallocarboxypeptidase D. J. Biol. Chem. 271, 28884-28889.
32. Song, L., and Fricker, L.D. (1997). The pro region is not required for the expression or intracellular routing of carboxypeptidase E. Biochem. J. 323, 265-271.
33. Tan, F., Rehli, M., Krause, S.W., and Skidgel, R.A. (1997). Sequence of human carboxypeptidase D reveals it to be a member of the regulatory carboxypeptidase family with three tandem active site domains. Biochem. J. 327, 81-87.
34. Tausk, F.A., Milgram, S.L., Mains, R.E., and Eipper, B.A. (1992). Expression of a peptide processing enzyme in cultured cells: truncation mutants reveal a routing domain. Mol. Endocrinol. 6, 2185-2196.
35. Varlamov, O., and Fricker, L.D. (1998). Intracellular trafficking of metallocarboxypeptidase D in AtT-20 cells: localization to the Golgi and recycling from the cell surface. J. Cell Sci. 111, 877-885.
36. Voorhees, P., Deignan, E., van Donselaar, E., Humphrey, J., Marks, M.S., Peters, P.J., and Bonifacino, J.S. (1995). An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface. EMBO J. 14, 4961-4975.
37. Wan, L., Molloy, S.S., Thomas, L., Liu, G., Xiang, Y., Rybak, S.L., and Thomas, G. (1998). PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization. Cell 94, 205-216.
38. Wong, S.H., and Hong, W. (1993). The SXYQRL sequence in the cytoplasmic domain of TGN38 plays a major role in trans-Golgi network localization. J. Biol. Chem. 268, 22853-22862.
39. Xin, X., Varlamov, O., Day, R., Dong, W., Bridgett, M.M., Leiter, E.H., and Fricker, L.D. (1997). Cloning and sequence analysis of cDNA encoding rat carboxypeptidase D. DNA Cell Biol. 16, 897-909.