Role of α 2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice

British Journal of Pharmacology

Volumn 152, Issue 1, 2007, Pages 91-100

  Honda, M ^a   Suzuki, M ^a   Nakayama, K ^a,b   Ishikawa, T ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Cold induced vasoconstriction; Laser Doppler flowmetry; Rho kinase; Tetrodotoxin; Thermoregulation

Indexed keywords

1,3,4,5',6,6',7,12B OCTAHYDRO 1',3' DIMETHYL 2H SPIRO[BENZO[B]FURO[2,3 A]QUINOLIZINE 2,4' PYRIMIDINE] 2' ONE; 12 ETHYLSULFONYL 5,8,8A,9,10,11,12,12A,13,13A DECAHYDRO 3 METHOXY 6H ISOQUINO[2,1 G][1,6]NAPHTHYRIDINE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACETYLCHOLINE; ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 2C ADRENERGIC RECEPTOR; BRETYLIUM; BUNAZOSIN; CLONIDINE; FASUDIL; GUANETHIDINE; H 1152; OPC 28326; PENTOBARBITAL; PHENTOLAMINE; PHENYLEPHRINE; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RHO KINASE INHIBITOR; TETRODOTOXIN; UNCLASSIFIED DRUG; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 METHYL 1 ((4 METHYL 5 ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; 2-METHYL-1-((4-METHYL-5-ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; ADRENERGIC RECEPTOR ALPHA(2C); ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; AMIDE; DRUG DERIVATIVE; ISOQUINOLINE DERIVATIVE; LOCAL ANESTHETIC AGENT; NAPHTHYRIDINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; PYRIDINE DERIVATIVE; QUINOLIZINE DERIVATIVE; RHO KINASE; RHO-ASSOCIATED KINASE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COOLING; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MOUSE; NONHUMAN; PERFUSION; PRIORITY JOURNAL; SKIN; SKIN BLOOD FLOW; SKIN TEMPERATURE; TACHYCARDIA; THERMOREGULATION; VASOCONSTRICTION; ADRENALECTOMY; ADRENERGIC SYSTEM; ANIMAL; BLOOD FLOW; BLOOD PRESSURE; BLOOD VESSEL; COLD; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HEART RATE; INNERVATION; LASER DOPPLER FLOWMETRY; METABOLISM; PHYSIOLOGY; REFLEX; VASCULARIZATION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ADRENALECTOMY; ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; AMIDES; ANESTHETICS, LOCAL; ANIMALS; BLOOD PRESSURE; BLOOD VESSELS; BODY TEMPERATURE REGULATION; CLONIDINE; COLD; HEART RATE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOQUINOLINES; LASER-DOPPLER FLOWMETRY; MALE; MICE; NAPHTHYRIDINES; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; QUINOLIZINES; RECEPTORS, ADRENERGIC, ALPHA-2; REFLEX; REGIONAL BLOOD FLOW; SKIN; SKIN TEMPERATURE; SYMPATHETIC NERVOUS SYSTEM; TETRODOTOXIN; VASOCONSTRICTION;

EID: 34548329506     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707380     Document Type: Article

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