Distribution of α(2C)-adrenergic receptor-like immunoreactivity in the rat central nervous system

Journal of Comparative Neurology

Volumn 372, Issue 1, 1996, Pages 135-165

  Rosin, Diane L ^a   Talley, Edmund M ^a   Lee, Amy ^a   Stornetta, Ruth L ^a   Gaylinn, Bruce D ^a   Guyenet, Patrice G ^a   Lynch, Kevin R ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

adrenoceptors; antibody; epinephrine; immunohistochemistry; norepinephrine

Indexed keywords

ALPHA 2C ADRENERGIC RECEPTOR; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; MESSENGER RNA; POLYCLONAL ANTIBODY; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; GLOBUS PALLIDUS; GOAT; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; OLFACTORY NUCLEUS; PERIKARYON; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT; RECEPTOR DENSITY; SEPTUM PELLUCIDUM; SPINAL CORD;

ANIMALS; ANTIBODY SPECIFICITY; BRAIN CHEMISTRY; CEREBELLUM; DIENCEPHALON; IMMUNOHISTOCHEMISTRY; MALE; MESENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; RHOMBENCEPHALON; SPINAL CORD; TELENCEPHALON;

EID: 0029847017     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19960812)372:1<135::AID-CNE9>3.3.CO;2-B     Document Type: Article

References (62)

1. Alheid, G.F., J.S. de Olmos, and C.A. Beltramino (1995) Amygdala and extended amygdala. In G. Paxinos (ed): The Rat Nervous System. San Diego: Academic Press, pp. 495-578.
2. Amaral, D.G., and M.P. Witter (1995) Hippocampel formation. In G. Paxinos (ed): The Rat Nervous System. San Diego: Academic Press, pp. 443-494.
3. Aoki, C., BA. Zemcik, C.D. Strader, and V.M. Pickel (1989) Cytoplasmic loop of β-adrenergic receptors: Synaptic and intracellular localization and relation to catecholaminergic neurons in the nuclei of the solitary tracts. Brain Res. 493:331-347.
4. 2A-adrenergic receptor-like immunoreactivity. Brain Res. 650:181-204.
5. Bieger, D., and D. A. Hopkins (1987) Viscerotopic representation of the upper alimentary tract in the medulla oblongata in the rat: the nucleus ambiguus. J. Comp. Neurol. 262:546-562.
6. 3H]idazoxan in rat brain. J. Pharmacol. Exp. Ther. 241:1079-1091.
7. Breier, A. (1994) Clozapine and noradrenergic function: Support for a novel hypothesis for superior efficacy. J. Clin. Psychiatr. 55(Suppl B): 122-125.
8. Breier, A., R.W. Buchanan, R.W. Waltrip, S. Listwak, C. Holmes, and D.S. Goldstein (1994) The effect of clozapine on plasma norepinephrine: Relationship to clinical efficacy. Neuropsychopharmacology 10:1-7.
9. Brennen, P., H. Kaba, and E.B. Keverne (1990) Olfactory recognition: A simple memory system. Science 250:1223-1226.
10. Briley, M., and M. Marien (1994) Noradrenergic Mechanisms in Parkinson's Disease. Boca Raton, FL: CRC Press, Inc.
11. Bylund, D.B. (1992) Subtypes of alpha 1- and alpha 2-adrenergic receptors. FASEB J. 6:832-839.
12. Cohen, L.J. (1994) Risperidone. Pharmacotherapy 14:253-265.
13. Faxe, K., and L.F. Agnati (1991) Advances in Neuroscience, Vol. 1, Volume Transmission in the Brain: Novel Mechanisms for Neural Transmission. New York: Raven.
14. Guan, K.L., and J.E. Dixon (1991) Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 192: 262-267.
15. 2A-adrenergic receptors are present in lower brainstem catecholaminergic and serotonergic neurons innervating spinal cord. Brain Res. 635:285-294.
16. +, and amiloride analogs. J. Biol. Chem. 265:17307-17317.
17. 2-adrenergic receptors. Mol. Pharmacol. 40:407-412.
18. Heimer, L., D.S. Zahm, and G.F. Alheid (1995) Basal ganglia. In G. Paxinos (ed): The Rat Nervous System. San Diego: Academic Press, pp. 579-628.
19. Herkenham, M. (1987) Mismatches between neurotransmitter and receptor localizations in brain: Observations and implications. Neuroscience 23:1-38.
20. Jones, B.E. (1991) Noradrenergic locus coeruleus neurons: their distant connections and their relationship to neighboring (including cholinergic and GABAergic) neurons of the central gray and reticular formation. Progr. Brain Res. 88:15-30.
21. Joyce, J.N. (1993) The dopamine hypothesis of schizophrenia: Limbic interactions with serotonin and norepinephrine. Psychopharmacology 112:S16-S34.
22. Kahn, R.S., and M. Davidson (1993) Serotonin, dopamine and their interactions in schizophrenia [editorial]. Psychopharmacology 112:S1-S4.
23. 2-adrenergic receptor. Science 238:650-656.
24. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 227:680-685.
25. 2-adrenergic receptor using a radioiodinated arylazide derivative of rauwolscine: Identification of the hormone-binding subunit. Proc. Natl. Acad. Sci. USA 83:9358-9362.
26. 2-adrenergic receptors. J. Biol. Chem. 263:14491-14496.
27. 2-adrenergic receptor. Identification of a unique receptor subtype. J. Biol. Chem. 266:10470-10478.
28. 2A adrenergic receptors in a neuronal cell line. Neuroendocrinology 62:215-225.
29. Levey, A.I., C.A. Kitt, W.F. Simonds, D.L. Price, and M.R. Brann (1991) Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies. J Neurosci 11:3218-3226.
30. 2 dopamine receptors in brain with subtype-specific antibodies. Proc. Natl. Acad. Sci. USA 90:8861-8865.
31. Link, R., D. Daunt, G. Barsh, A. Chruscinski, and B. Kobilka (1992) Cloning of two mouse genes encoding alpha 2-adrenergic receptor subtypes and identification of a single amino acid in the mouse alpha 2-C10 homolog responsible for an interspecies variation in antagonist binding. Mol. Pharmacol. 42:16-27.
32. 2-adrenergic receptor subtype, the gene for which is located on chromosome 2. Proc. Natl. Acad. Sci. USA 87:5094-5098.
33. Lomasney, J.W., S. Cotecchia, R.J. Lefkowitz, and M.G. Caron (1991) Molecular biology of alpha-adrenergic receptors: Implications for receptor classification and for structure-function relationships. Biochim. Biophys. Acta 1095:127-139.
34. Lynch, K.R., J.K. Harrison, and W.R. Pearson (1995) Classification of adrenergic receptors: Molecular biological approaches. Neuroprotocols 4:14-19.
35. McCune, S.K., M.M. Voigt, and J.M. Hill (1993) Expression of multiple alpha adrenergic receptor subtype messenger RNAs in the adult rat brain. Neuroscience 57:143-151.
36. Meltzer, H.Y. (1994) An overview of the mechanism of action of clozapine. J. Clin. Psychiatr. 55(Suppl B):47-52.
37. Moore, R.Y., and P. Card (1984) Noradrenaline-containing neuron systems. In A. Bjorklund and T. Hokfelt (eds): Handbook of Chemical Neuroanatomy, Vol. 2: Classical Transmitters in the CNS, Part I. Amsterdam: Elsevier, pp. 123-156.
38. Nakaya, Y., T. Kaneko, R. Shigemoto, S. Nakanishi, and N. Mizuno (1994) Immunohistochemical localization of substance P receptor in the central nervous system of the adult rat. J. Comp. Neurol. 347:249-274.
39. Nicholas, A.P., V. Pieribone, and T. Hokfelt (1993a) Distributions of mRNAs for alpha-2 adrenergic receptor subtypes in rat brain: an in situ hybridization study. J. Comp. Neurol. 328:575-594.
40. Nicholas, A.P., V.A. Pieribone, and T. Hokfelt (1993b) Cellular localization of messenger RNA for beta-1 and beta-2 adrenergic receptors in rat brain: An in situ hybridization study. Neuroscience 56:1023-1039.
41. Okusa, M.D., K.R. Lynch, D.L. Rosin, L. Huang, and Y.Y. Wei (1994) Apical membrane and intracellular distribution of endogenous alpha 2A-adrenergic receptors in MDCK cells. Am. J. Physiol. 267:F347-F353.
42. Parkis, M.A., D.A. Bayliss, and A.J. Berger (1995) Actions of norepinephrine on rat hypoglossal motoneurons. J. Neurophysiol. 74:1911-1919.
43. Paxinos, G., and C. Watson (1986) The Rat Brain in Stereotaxic Coordinates. San Diego: Academic Press.
44. Pearson, W.R. (1995) Comparison of methods for searching protein sequence databases. Protein Sci. 4:1145-1160.
45. 2-adrenergic receptor subtype. Proc. Natl. Acad. Sci. USA 85:6301-6305.
46. 2-adrenergic receptor from porcine brain using a yohimbine-agarose affinity matrix. J. Biol. Chem. 262:12381-12386.
47. 2A-adrenergic receptors in catecholaminergic and other brainstem neurons in the rat. Neuroscience. 56:139-155.
48. 2A-adrenergic receptors in rat forebrain: Light and electron microscopy. Soc. Neurosci. Abstr. 21:1622.
49. Ruffolo, R.R., Jr., A.J. Nichols, J.M. Stadel, and J.P. Hieble (1991) Structure and function of alpha-adrenoceptors. Pharmacol. Rev. 43:475-505.
50. Ruggiero, D.A., S.L. Cravo, V. Arango, and D.J. Reis (1989) Central control of the circulation by the rostral ventrolateral reticular nucleus: anatomical substrates. In J. Ciriello, M.M. Caverson, and C. Polosa (eds): Progr. Brain Res. Vol. 81: The Central Neural Organization of Cardiovascular Control. Amsterdam: Elsevier, pp. 49-79.
51. Scheinin, M., J.W. Lomasney, D.M. Hayden-Hixson, U.B. Schambra, M.G. Caron, R.J. Lefkowitz, and R.T. Fremeau, Jr. (1994) Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain. Mol. Brain Res. 27:133-149.
52. 2 receptor-like immunoreactivity in midbrain dopamine neurons and their striatal targets. J. Neurosci. 14:88-106.
53. Shipley, M.T., J.H. McLean, and M. Ennis (1995) Olfactory system. In G. Paxinos (ed): The Rat Nervous System. San Diego: Academic Press, pp. 899-928.
54. Simerly, R.B. (1995) Anatomical substrates of hypothalamic integration. In G. Paxinos (ed): The Rat Nervous System. San Diego: Academic Press, pp. 353-376.
55. Smith, D.B., and K.S. Johnson (1988) Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
56. 2A-adrenergic receptor-like immunoreactivity in the rat central nervous system. J. Comp. Neurol. 372:111-134.
57. Trombley, P.Q., and G.M. Shepherd (1992) Noradrenergic inhibition of synaptic transmission between mitral and granule cells in mammalian olfactory bulb cultures. J. Neurosci. 12:3985-3991.
58. 2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents. Brain Res. 319:69-101.
59. 2-adrenergic receptor subtypes in brain. Pharmacol. Biochem. Behav. 41:267-273.
60. 2-adrenergic receptor mRNAs in the rat CNS. Mol. Brain Res. 10:219-225.
61. 2B-adrenergic receptor. Proc. Natl. Acad. Sci. USA 87:3102-3106.
62. Zilles, K., M. Qu, and A. Schleicher (1993) Regional distribution and heterogeneity of alpha-adrenoceptors in the rat and human central nervous system. J. Hirnforschung. 34:123-132.