메뉴 건너뛰기




Volumn 2011, Issue , 2011, Pages

Myelodysplastic syndrome and histone deacetylase inhibitors: To be or not to be acetylated?

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ARYLBUTYRIC ACID DERIVATIVE; AZACITIDINE; BELINOSTAT; BUTYRIC ACID; CYCLOSPORIN; DEFERASIROX; DEFEROXAMINE; DEPSIPEPTIDE; ENTINOSTAT; ERYTHROPOIETIN; GYRASE INHIBITOR; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE 7; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE INHIBITOR; LENALIDOMIDE; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PANOBINOSTAT; PYROXAMIDE; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RETINOIC ACID; ROMIDEPSIN; TACEDINALINE; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG; VALPROIC ACID; VORINOSTAT; ZEBULARINE; HISTONE DEACETYLASE;

EID: 79959348192     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2011/214143     Document Type: Review
Times cited : (20)

References (154)
  • 1
    • 0019952276 scopus 로고
    • Proposals for the classification of the myelodysplastic syndromes
    • Bennett J. M., Catovsky D., Daniel M. T., Proposals for the classification of the myelodysplastic syndromes British Journal of Haematology 1982 51 2 189 199 (Pubitemid 12073508)
    • (1982) British Journal of Haematology , vol.51 , Issue.2 , pp. 189-199
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3
  • 2
    • 13444269356 scopus 로고    scopus 로고
    • Myelodysplastic syndromescoping with ineffective hematopoiesis
    • Cazzola M., Malcovati L., Myelodysplastic syndromescoping with ineffective hematopoiesis New England Journal of Medicine 2005 352 6 536 538
    • (2005) New England Journal of Medicine , vol.352 , Issue.6 , pp. 536-538
    • Cazzola, M.1    Malcovati, L.2
  • 7
    • 48749111872 scopus 로고    scopus 로고
    • Molecular pathways in myelodysplastic syndromes and acute myeloid leukemia: Relationships and distinctionsa review
    • Bernasconi P., Molecular pathways in myelodysplastic syndromes and acute myeloid leukemia: relationships and distinctionsa review British Journal of Haematology 2008 142 5 695 708
    • (2008) British Journal of Haematology , vol.142 , Issue.5 , pp. 695-708
    • Bernasconi, P.1
  • 8
    • 0021250450 scopus 로고
    • Evidence for a multistep pathogenesis of a myelodysplastic syndrome
    • Raskind W. H., Tirumali N., Jacobson R., Evidence for a multistep pathogenesis of a myelodysplastic syndrome Blood 1984 63 6 1318 1323 (Pubitemid 14120375)
    • (1984) Blood , vol.63 , Issue.6 , pp. 1318-1323
    • Raskind, W.H.1    Tirumali, N.2    Jacobson, R.3
  • 9
    • 0033967640 scopus 로고    scopus 로고
    • A hypothesis for the pathogenesis of myelodysplastic syndromes: Implications for new therapies
    • Rosenfeld C., List A., A hypothesis for the pathogenesis of myelodysplastic syndromes: implications for new therapies Leukemia 2000 14 1 2 8 (Pubitemid 30068366)
    • (2000) Leukemia , vol.14 , Issue.1 , pp. 2-8
    • Rosenfeld, C.1    List, A.2
  • 10
    • 0038470905 scopus 로고    scopus 로고
    • Molecular mechanisms of myelodysplastic syndrome
    • DOI 10.1093/jjco/hyg037
    • Hirai H., Molecular mechanisms of myelodysplastic syndrome Japanese Journal of Clinical Oncology 2003 33 4 153 160 (Pubitemid 43102857)
    • (2003) Japanese Journal of Clinical Oncology , vol.33 , Issue.4 , pp. 153-160
    • Hirai, H.1
  • 11
    • 50849085449 scopus 로고    scopus 로고
    • Myelodysplastic syndromes: Molecular pathogenesis and genomic changes
    • Nolte F., Hofmann W. K., Myelodysplastic syndromes: molecular pathogenesis and genomic changes Annals of Hematology 2008 87 10 777 795
    • (2008) Annals of Hematology , vol.87 , Issue.10 , pp. 777-795
    • Nolte, F.1    Hofmann, W.K.2
  • 13
    • 77954323523 scopus 로고    scopus 로고
    • Current therapeutic approaches for patients with myelodysplastic syndromes
    • Greenberg P. L., Current therapeutic approaches for patients with myelodysplastic syndromes British Journal of Haematology 2010 150 2 131 143
    • (2010) British Journal of Haematology , vol.150 , Issue.2 , pp. 131-143
    • Greenberg, P.L.1
  • 14
    • 67349222049 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors as anti-neoplastic agents
    • Batty N., Malouf G. G., Issa J. P. J., Histone deacetylase inhibitors as anti-neoplastic agents Cancer Letters 2009 280 2 192 200
    • (2009) Cancer Letters , vol.280 , Issue.2 , pp. 192-200
    • Batty, N.1    Malouf, G.G.2    Issa, J.P.J.3
  • 15
    • 37549022694 scopus 로고    scopus 로고
    • DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes
    • Griffiths E. A., Gore S. D., DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes Seminars in Hematology 2008 45 1 23 30
    • (2008) Seminars in Hematology , vol.45 , Issue.1 , pp. 23-30
    • Griffiths, E.A.1    Gore, S.D.2
  • 16
    • 77950529126 scopus 로고    scopus 로고
    • Epigenetic changes in the myelodysplastic syndrome
    • Issa J. P., Epigenetic changes in the myelodysplastic syndrome Hematology/Oncology Clinics of North America 2010 24 2 317 330
    • (2010) Hematology/Oncology Clinics of North America , vol.24 , Issue.2 , pp. 317-330
    • Issa, J.P.1
  • 17
    • 46949098033 scopus 로고    scopus 로고
    • Current status of epigenetic treatment in myelodysplastic syndromes
    • Kuendgen A., Lbbert M., Current status of epigenetic treatment in myelodysplastic syndromes Annals of Hematology 2008 87 8 601 611
    • (2008) Annals of Hematology , vol.87 , Issue.8 , pp. 601-611
    • Kuendgen, A.1    Lbbert, M.2
  • 18
    • 46749151451 scopus 로고    scopus 로고
    • Myelodysplastic syndromes
    • Nimer S. D., Myelodysplastic syndromes Blood 2008 111 10 4841 4851
    • (2008) Blood , vol.111 , Issue.10 , pp. 4841-4851
    • Nimer, S.D.1
  • 19
    • 0031970275 scopus 로고    scopus 로고
    • Diagnosis, classification, and cytogenetics of myelodysplastic syndromes
    • Vallesp T., Imbert M., Mecucci C., Preudhomme C., Fenaux P., Diagnosis, classification, and cytogenetics of myelodysplastic syndromes Haematologica 1998 83 3 258 275 (Pubitemid 28209132)
    • (1998) Haematologica , vol.83 , Issue.3 , pp. 258-275
    • Vallespi, T.1    Imbert, M.2    Mecucci, C.3    Preudhomme, C.4    Fenaux, P.5
  • 20
    • 0033609317 scopus 로고    scopus 로고
    • Myelodysplasia
    • DOI 10.1056/NEJM199905273402107
    • Heaney M. L., Golde D. W., Myelodysplasia New England Journal of Medicine 1999 340 21 1649 1660 (Pubitemid 29249435)
    • (1999) New England Journal of Medicine , vol.340 , Issue.21 , pp. 1649-1660
    • Heaney, M.L.1    Golde, D.W.2
  • 21
    • 0034063502 scopus 로고    scopus 로고
    • Myelodysplastisches syndrom (MDS). Aspekte der hamatopathologischen diagnostik
    • Schmitt-Graeff A., Mattern D., Khler H., Hezel J., Lbbert M., Myelodysplastic syndromes: aspects of hematopathologic diagnosis Pathologe 2000 21 1 1 15 (Pubitemid 30163192)
    • (2000) Pathologe , vol.21 , Issue.1 , pp. 1-15
    • Schmitt-Graeff, A.1    Mattern, D.2    Kohler, H.3    Hezel, J.4    Lubbert, M.5
  • 24
    • 5744243856 scopus 로고    scopus 로고
    • Pathobiology, classification, and diagnosis of myelodysplastic syndrome
    • DOI 10.1016/j.beha.2004.08.007, PII S1521692604000738
    • Mufti G. J., Pathobiology, classification, and diagnosis of myelodysplastic syndrome Best Practice and Research: Clinical Haematology 2004 17 4 543 557 (Pubitemid 39378186)
    • (2004) Best Practice and Research: Clinical Haematology , vol.17 , Issue.4 SPEC.ISS. , pp. 543-557
    • Mufti, G.J.1
  • 25
    • 0034210220 scopus 로고    scopus 로고
    • Therapy-related acute myeloid leukemia and myelodysplasia after high- dose chemotherapy and autologous stem cell transplantation
    • Pedersen-Bjergaard J., Andersen M. K., Christiansen D. H., Therapy-related acute myeloid leukemia and myelodysplasia after high-dose chemotherapy and autologous stem cell transplantation Blood 2000 95 11 3273 3279 (Pubitemid 30428453)
    • (2000) Blood , vol.95 , Issue.11 , pp. 3273-3279
    • Pedersen-Bjergaard, J.1    Andersen, M.K.2    Christiansen, D.H.3
  • 26
    • 0028474547 scopus 로고
    • Secondary myelodysplastic syndromes and leukemias
    • Giles F. J., Koeffler H. P., Secondary myelodysplastic syndromes and leukemias Current Opinion in Hematology 1994 1 4 256 260
    • (1994) Current Opinion in Hematology , vol.1 , Issue.4 , pp. 256-260
    • Giles, F.J.1    Koeffler, H.P.2
  • 27
    • 0037085745 scopus 로고    scopus 로고
    • Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia
    • DOI 10.1182/blood.V99.6.1909
    • Pedersen-Bjergaard J., Andersen M. K., Christiansen D. H., Nerlov C., Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia Blood 2002 99 6 1909 1912 (Pubitemid 34525468)
    • (2002) Blood , vol.99 , Issue.6 , pp. 1909-1912
    • Pedersen-Bjergaard, J.1    Andersen, M.K.2    Christiansen, D.H.3    Nerlov, C.4
  • 28
    • 0031981671 scopus 로고    scopus 로고
    • Increasing incidence of myelodysplastic syndromes: Real or fictitious?
    • DOI 10.1016/S0145-2126(97)00089-1, PII S0145212697000891
    • Aul C., Germing U., Gattermann N., Minning H., Increasing incidence of myelodysplastic syndromes: real or fictitious? Leukemia Research 1998 22 1 93 100 (Pubitemid 28167552)
    • (1998) Leukemia Research , vol.22 , Issue.1 , pp. 93-100
    • Aul, C.1    Germing, U.2    Gattermann, N.3    Minning, H.4
  • 29
    • 0026688084 scopus 로고
    • Age-related incidence and other epidemiological aspects of myelodysplastic syndromes
    • Aul C., Gattermann N., Schneider W., Age-related incidence and other epidemiological aspects of myelodysplastic syndromes British Journal of Haematology 1992 82 2 358 367
    • (1992) British Journal of Haematology , vol.82 , Issue.2 , pp. 358-367
    • Aul, C.1    Gattermann, N.2    Schneider, W.3
  • 33
    • 33846449861 scopus 로고    scopus 로고
    • Cost effectiveness of lenalidomide in the treatment of transfusion- dependent myelodysplastic syndromes in the United States
    • Goss T. F., Szende A., Schaefer C., Totten P. J., Knight R., Jdersten M., Hellstrm-Lindberg E., List A. F., Cost effectiveness of lenalidomide in the treatment of transfusion-dependent myelodysplastic syndromes in the United States Cancer Control 2006 13, supplement 17 25 (Pubitemid 46148106)
    • (2006) Cancer Control , vol.13 , Issue.SUPPL. , pp. 17-25
    • Goss, T.F.1    Szende, A.2    Schaefer, C.3    Totten, P.4    Knight, R.5    Jadersten, M.6    Hellstrom-Lindberg, E.7    List, A.F.8
  • 34
    • 56049091053 scopus 로고    scopus 로고
    • The costs of drugs used to treat myelodysplastic syndromes following national comprehensive cancer network guidelines
    • Greenberg P. L., Cosler L. E., Ferro S. A., Lyman G. H., The costs of drugs used to treat myelodysplastic syndromes following national comprehensive cancer network guidelines Journal of the National Comprehensive Cancer Network 2008 6 9 942 953
    • (2008) Journal of the National Comprehensive Cancer Network , vol.6 , Issue.9 , pp. 942-953
    • Greenberg, P.L.1    Cosler, L.E.2    Ferro, S.A.3    Lyman, G.H.4
  • 35
    • 79959352030 scopus 로고    scopus 로고
    • Incidence and other aspects of myelodysplastic syndrome in the Austrian federal state Salzburg
    • Kemmerling R., Neureiter D., Faber V., Incidence and other aspects of myelodysplastic syndrome in the Austrian federal state Salzburg Pathology Research and Practice 2007 203 5 392 392
    • (2007) Pathology Research and Practice , vol.203 , Issue.5 , pp. 392-392
    • Kemmerling, R.1    Neureiter, D.2    Faber, V.3
  • 36
    • 0031906395 scopus 로고    scopus 로고
    • Pathogenesis, etiology and epidemiology of myelodysplastic syndromes
    • Aul C., Bowen D. T., Yoshida Y., Pathogenesis, etiology and epidemiology of myelodysplastic syndromes Haematologica 1998 83 1 71 86 (Pubitemid 28096504)
    • (1998) Haematologica , vol.83 , Issue.1 , pp. 71-86
    • Aul, C.1    Bowen, D.T.2    Yoshida, Y.3
  • 37
    • 0031782686 scopus 로고    scopus 로고
    • Hypothesis: Myelodysplastic syndromes may have a viral etiology
    • PII S0925571098000516
    • Raza A., Hypothesis: myelodysplastic syndromes may have a viral etiology International Journal of Hematology 1998 68 3 245 256 (Pubitemid 28522550)
    • (1998) International Journal of Hematology , vol.68 , Issue.3 , pp. 245-256
    • Raza, A.1
  • 38
    • 0035200467 scopus 로고    scopus 로고
    • Myelodysplastic syndrome: Review of the cytogenetic and molecular data
    • DOI 10.1016/S1040-8428(01)00101-9, PII S1040842801001019
    • Mhawech P., Saleem A., Myelodysplastic syndrome: review of the cytogenetic and molecular data Critical Reviews in Oncology/Hematology 2001 40 3 229 238 (Pubitemid 33111069)
    • (2001) Critical Reviews in Oncology/Hematology , vol.40 , Issue.3 , pp. 229-238
    • Mhawech, P.1    Saleem, A.2
  • 42
    • 33846389406 scopus 로고    scopus 로고
    • High-Resolution Genomic Arrays Facilitate Detection of Novel Cryptic Chromosomal Lesions in Myelodysplastic Syndromes
    • DOI 10.1016/j.exphem.2006.09.016, PII S0301472X06006370
    • O'Keefe C. L., Tiu R., Gondek L. P., Powers J., Theil K. S., Kalaycio M., Lichtin A., Sekeres M. A., Maciejewski J. P., High-resolution genomic arrays facilitate detection of novel cryptic chromosomal lesions in myelodysplastic syndromes Experimental Hematology 2007 35 2 240 251 (Pubitemid 46135810)
    • (2007) Experimental Hematology , vol.35 , Issue.2 , pp. 240-251
    • O'Keefe, C.L.1    Tiu, R.2    Gondek, L.P.3    Powers, J.4    Theil, K.S.5    Kalaycio, M.6    Lichtin, A.7    Sekeres, M.A.8    Maciejewski, J.P.9
  • 43
    • 0029919109 scopus 로고    scopus 로고
    • Hereditary cancer: Two hits revisited
    • DOI 10.1007/BF01366952
    • Knudson A. G., Hereditary cancer: two hits revisited Journal of Cancer Research and Clinical Oncology 1996 122 3 135 140 (Pubitemid 26076883)
    • (1996) Journal of Cancer Research and Clinical Oncology , vol.122 , Issue.3 , pp. 135-140
    • Knudson, A.G.1
  • 44
    • 0037438508 scopus 로고    scopus 로고
    • Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia
    • DOI 10.1182/blood-2002-04-1010
    • Harada H., Harada Y., Tanaka H., Kimura A., Inaba T., Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia Blood 2003 101 2 673 680 (Pubitemid 36077592)
    • (2003) Blood , vol.101 , Issue.2 , pp. 673-680
    • Harada, H.1    Harada, Y.2    Tanaka, H.3    Kimura, A.4    Inaba, T.5
  • 45
    • 0842322951 scopus 로고    scopus 로고
    • Familial mutations of the transcription factor RUNX1 (AML1, CBFA2) predispose to acute myeloid leukemia
    • DOI 10.1080/1042819031000139611
    • Ganly P., Walker L. C., Morris C. M., Familial mutations of the transcription factor RUNX1 (AML1, CBFA2) predispose to acute myeloid leukemia Leukemia and Lymphoma 2004 45 1 1 10 (Pubitemid 38181387)
    • (2004) Leukemia and Lymphoma , vol.45 , Issue.1 , pp. 1-10
    • Ganly, P.1    Walker, L.C.2    Morris, C.M.3
  • 47
    • 33750326207 scopus 로고    scopus 로고
    • Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia
    • DOI 10.1038/sj.leu.2404381, PII 2404381
    • Pedersen-Bjergaard J., Christiansen D. H., Desta F., Andersen M. K., Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia Leukemia 2006 20 11 1943 1949 (Pubitemid 44614882)
    • (2006) Leukemia , vol.20 , Issue.11 , pp. 1943-1949
    • Pedersen-Bjergaard, J.1    Christiansen, D.H.2    Desta, F.3    Andersen, M.K.4
  • 48
    • 0034490531 scopus 로고    scopus 로고
    • Abnormalities of adherent layers grown from bone marrow of patients with myelodysplasia
    • DOI 10.1046/j.1365-2141.2000.02467.x
    • Tennant G. B., Walsh V., Truran L. N., Edwards P., Mills K. I., Burnett A. K., Abnormalities of adherent layers grown from bone marrow of patients with myelodysplasia British Journal of Haematology 2000 111 3 853 862 (Pubitemid 32098923)
    • (2000) British Journal of Haematology , vol.111 , Issue.3 , pp. 853-862
    • Tennant, G.B.1    Walsh, V.2    Truran, L.N.3    Edwards, P.4    Mills, K.I.5    Burnett, A.K.6
  • 49
    • 0036236034 scopus 로고    scopus 로고
    • In vitro characterization of hematopoietic microenvironment cells from patients with myelodysplastic syndrome
    • DOI 10.1016/S0145-2126(01)00193-X, PII S014521260100193X
    • Flores-Figueroa E., Gutirrez-Espndola G., Montesinos J. J., Arana-Trejo R. M., Mayani H., In vitro characterization of hematopoietic microenvironment cells from patients with myelodysplastic syndrome Leukemia Research 2002 26 7 677 686 (Pubitemid 34465704)
    • (2002) Leukemia Research , vol.26 , Issue.7 , pp. 677-686
    • Flores-Figueroa, E.1    Gutierrez-Espindola, G.2    Montesinos, J.J.3    Arana-Trejo, R.M.4    Mayani, H.5
  • 51
    • 0035283119 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes
    • DOI 10.1182/blood.V97.5.1427
    • Bellamy W. T., Richter L., Sirjani D., Roxas C., Glinsmann-Gibson B., Frutiger Y., Grogan T. M., List A. F., Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes Blood 2001 97 5 1427 1434 (Pubitemid 32183769)
    • (2001) Blood , vol.97 , Issue.5 , pp. 1427-1434
    • Bellamy, W.T.1    Richter, L.2    Sirjani, D.3    Roxas, C.4    Glinsmann-Gibson, B.5    Frutiger, Y.6    Grogan, T.M.7    List, A.F.8
  • 52
    • 39149091719 scopus 로고    scopus 로고
    • Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes
    • DOI 10.1111/j.1600-0609.2007.01012.x
    • Travaglino E., Benatti C., Malcovati L., Porta M. G. D., Gall A., Bonetti E., Rosti V., Cazzola M., Invernizzi R., Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes European Journal of Haematology 2008 80 3 216 226 (Pubitemid 351253461)
    • (2008) European Journal of Haematology , vol.80 , Issue.3 , pp. 216-226
    • Travaglino, E.1    Benatti, C.2    Malcovati, L.3    Porta, M.G.D.4    Galli, A.5    Bonetti, E.6    Rosti, V.7    Cazzola, M.8    Invernizzi, R.9
  • 53
    • 13244290233 scopus 로고    scopus 로고
    • Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes
    • Campioni D., Secchiero P., Corallini F., Melloni E., Capitani S., Lanza F., Zauli G., Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes American Journal of Pathology 2005 166 2 557 563 (Pubitemid 40189051)
    • (2005) American Journal of Pathology , vol.166 , Issue.2 , pp. 557-563
    • Campioni, D.1    Secchiero, P.2    Corallini, F.3    Melloni, E.4    Capitani, S.5    Lanza, F.6    Zauli, G.7
  • 55
    • 28444479122 scopus 로고    scopus 로고
    • NF-κB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs)
    • DOI 10.1182/blood-2005-04-1424
    • Kerbauy D. M. B., Lesnikov V., Abbasi N., Seal S., Scott B., Joachim Deeg H., NF- B and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs) Blood 2005 106 12 3917 3925 (Pubitemid 41739032)
    • (2005) Blood , vol.106 , Issue.12 , pp. 3917-3925
    • Kerbauy, D.M.B.1    Lesnikov, V.2    Abbasi, N.3    Seal, S.4    Scott, B.5    Joachim Deeg, H.6
  • 57
    • 22044450619 scopus 로고    scopus 로고
    • NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia
    • DOI 10.1182/blood-2004-12-4794
    • Lin Y. W., Slape C., Zhang Z., Aplan P. D., NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia Blood 2005 106 1 287 295 (Pubitemid 40967204)
    • (2005) Blood , vol.106 , Issue.1 , pp. 287-295
    • Lin, Y.-W.1    Slape, C.2    Zhang, Z.3    Aplan, P.D.4
  • 58
    • 24344437303 scopus 로고    scopus 로고
    • Role of nucleophosmin in embryonic development and tumorigenesis
    • DOI 10.1038/nature03915, PII N03915
    • Grisendi S., Bernardi R., Rossi M., Cheng KE., Khandker L., Manova K., Pandolfi P. P., Role of nucleophosmin in embryonic development and tumorigenesis Nature 2005 437 7055 147 153 (Pubitemid 41613442)
    • (2005) Nature , vol.437 , Issue.7055 , pp. 147-153
    • Grisendi, S.1    Bernardi, R.2    Rossi, M.3    Cheng, K.4    Khandker, L.5    Manova, K.6    Pandolfi, P.P.7
  • 61
    • 37549066376 scopus 로고    scopus 로고
    • Supportive care and use of hematopoietic growth factors in myelodysplastic syndromes
    • Hellstrm-Lindberg E., Malcovati L., Supportive care and use of hematopoietic growth factors in myelodysplastic syndromes Seminars in Hematology 2008 45 1 14 22
    • (2008) Seminars in Hematology , vol.45 , Issue.1 , pp. 14-22
    • Hellstrm-Lindberg, E.1    Malcovati, L.2
  • 62
    • 0037307728 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors
    • DOI 10.1182/blood-2002-06-1774
    • Tehranchi R., Fadeel B., Forsblom A. M., Christensson B., Samuelsson J., Zhivotovsky B., Hellstrom-Lindberg E., Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors Blood 2003 101 3 1080 1086 (Pubitemid 36139382)
    • (2003) Blood , vol.101 , Issue.3 , pp. 1080-1086
    • Tehranchi, R.1    Fadeel, B.2    Forsblom, A.-M.3    Christensson, B.4    Samuelsson, J.5    Zhivotovsky, B.6    Hellstrom-Lindberg, E.7
  • 63
    • 34248569916 scopus 로고    scopus 로고
    • Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality
    • DOI 10.1111/j.1600-0609.2007.00842.x
    • Takatoku M., Uchiyama T., Okamoto S., Kanakura Y., Sawada K., Tomonaga M., Nakao S., Nakahata T., Harada M., Murate T., Ozawa K., Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality European Journal of Haematology 2007 78 6 487 494 (Pubitemid 46753591)
    • (2007) European Journal of Haematology , vol.78 , Issue.6 , pp. 487-494
    • Takatoku, M.1    Uchiyama, T.2    Okamoto, S.3    Kanakura, Y.4    Sawada, K.5    Tomonaga, M.6    Nakao, S.7    Nakahata, T.8    Harada, M.9    Murate, T.10    Ozawa, K.11
  • 65
    • 23044473715 scopus 로고    scopus 로고
    • Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome
    • DOI 10.1182/blood-2004-05-2017
    • Sloand E. M., Mainwaring L., Fuhrer M., Ramkissoon S., Risitano A. M., Keyvanafar K., Lu J., Basu A., Barrett A. J., Young N. S., Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome Blood 2005 106 3 841 851 (Pubitemid 41076423)
    • (2005) Blood , vol.106 , Issue.3 , pp. 841-851
    • Sloand, E.M.1    Mainwaring, L.2    Fuhrer, M.3    Ramkissoon, S.4    Risitano, A.M.5    Keyvanafar, K.6    Lu, J.7    Basu, A.8    Barrett, A.J.9    Young, N.S.10
  • 66
    • 0036840455 scopus 로고    scopus 로고
    • Effects of cyclosporine on hematopoietic and immune functions in patients with hypoplastic myelodysplasia: In vitro and in vivo studies
    • DOI 10.1002/cncr.10915
    • Selleri C., Maciejewski J. P., Catalano L., Ricci P., Andretta C., Luciano L., Rotoli B., Effects of cyclosporine on hematopoietic and immune functions in patients with hypoplastic myelodysplasia: in vitro and in vivo studies Cancer 2002 95 9 1911 1922 (Pubitemid 35222171)
    • (2002) Cancer , vol.95 , Issue.9 , pp. 1911-1922
    • Selleri, C.1    Maciejewski, J.P.2    Catalano, L.3    Ricci, P.4    Andretta, C.5    Luciano, L.6    Rotoli, B.7
  • 67
    • 30844462355 scopus 로고    scopus 로고
    • The fundamental role of epigenetics in hematopoietic malignancies
    • DOI 10.1016/j.blre.2005.01.006, PII S0268960X0500007X
    • Galm O., Herman J. G., Baylin S. B., The fundamental role of epigenetics in hematopoietic malignancies Blood Reviews 2006 20 1 1 13 (Pubitemid 43106714)
    • (2006) Blood Reviews , vol.20 , Issue.1 , pp. 1-13
    • Galm, O.1    Herman, J.G.2    Baylin, S.B.3
  • 69
    • 34249810897 scopus 로고    scopus 로고
    • Acute myeloid leukemia and myelodysplastic syndromes in older patients
    • DOI 10.1200/JCO.2006.10.2731
    • Estey E., Acute myeloid leukemia and myelodysplastic syndromes in older patients Journal of Clinical Oncology 2007 25 14 1908 1915 (Pubitemid 46854425)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.14 , pp. 1908-1915
    • Estey, E.1
  • 70
    • 0035895052 scopus 로고    scopus 로고
    • Comparison of idarubicin + ara-C-, fludarabine + ara-C-, and topotecan + ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts
    • Estey E. H., Thall P. F., Cortes J. E., Giles F. J., O'Brien S., Pierce S. A., Wang X., Kantarjian H. M., Beran M., Comparison of idarubicin + ara-C-, fludarabine + ara-C-, and topotecan + ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts Blood 2001 98 13 3575 3583
    • (2001) Blood , vol.98 , Issue.13 , pp. 3575-3583
    • Estey, E.H.1    Thall, P.F.2    Cortes, J.E.3    Giles, F.J.4    O'Brien, S.5    Pierce, S.A.6    Wang, X.7    Kantarjian, H.M.8    Beran, M.9
  • 72
    • 3042821845 scopus 로고    scopus 로고
    • Novel therapies for myelodysplastic syndromes
    • DOI 10.1002/cncr.20381
    • Faderl S., Kantarjian H. M., Novel therapies for myelodysplastic syndromes Cancer 2004 101 2 226 241 (Pubitemid 38890824)
    • (2004) Cancer , vol.101 , Issue.2 , pp. 226-241
    • Faderl, S.1    Kantarjian, H.M.2
  • 73
    • 0037444803 scopus 로고    scopus 로고
    • Histone deacetylases (HDACs): Characterization of the classical HDAC family
    • DOI 10.1042/BJ20021321
    • De Ruijter A. J. M., Van Gennip A. H., Caron H. N., Kemp S., Van Kuilenburg A. B. P., Histone deacetylases (HDACs): characterization of the classical HDAC family Biochemical Journal 2003 370 3 737 749 (Pubitemid 36399066)
    • (2003) Biochemical Journal , vol.370 , Issue.3 , pp. 737-749
    • De Ruijter, A.J.M.1    Van Gennip, A.H.2    Caron, H.N.3    Kemp, S.4    Van Kuilenburg, A.B.P.5
  • 74
    • 34547864236 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Molecular mechanisms of action
    • DOI 10.1038/sj.onc.1210620, PII 1210620
    • Xu W. S., Parmigiani R. B., Marks P. A., Histone deacetylase inhibitors: molecular mechanisms of action Oncogene 2007 26 37 5541 5552 (Pubitemid 47255934)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5541-5552
    • Xu, W.S.1    Parmigiani, R.B.2    Marks, P.A.3
  • 75
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R. A., The hallmarks of cancer Cell 2000 100 1 57 70 (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 76
    • 0345357773 scopus 로고    scopus 로고
    • Gene Silencing in Cancer in Association with Promoter Hypermethylation
    • DOI 10.1056/NEJMra023075
    • Herman J. G., Baylin S. B., Gene silencing in cancer in association with promoter hypermethylation New England Journal of Medicine 2003 349 21 2042 2054 (Pubitemid 37448928)
    • (2003) New England Journal of Medicine , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 77
    • 40849139208 scopus 로고    scopus 로고
    • Molecular origins of cancer: Epigenetics in cancer
    • Esteller M., Molecular origins of cancer: epigenetics in cancer New England Journal of Medicine 2008 358 11 1148 1159
    • (2008) New England Journal of Medicine , vol.358 , Issue.11 , pp. 1148-1159
    • Esteller, M.1
  • 78
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P. A., Baylin S. B., The fundamental role of epigenetic events in cancer Nature Reviews Genetics 2002 3 6 415 428 (Pubitemid 34587077)
    • (2002) Nature Reviews Genetics , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 79
    • 27544505676 scopus 로고    scopus 로고
    • Chromatin modifier enzymes, the histone code and cancer
    • DOI 10.1016/j.ejca.2005.08.010, PII S0959804905007100, Transcription Factors in Cancer
    • Santos-Rosa H., Caldas C., Chromatin modifier enzymes, the histone code and cancer European Journal of Cancer 2005 41 16 2381 2402 (Pubitemid 41540617)
    • (2005) European Journal of Cancer , vol.41 , Issue.16 , pp. 2381-2402
    • Santos-Rosa, H.1    Caldas, C.2
  • 81
    • 34547549214 scopus 로고    scopus 로고
    • Epigenetic therapy in cancer: Molecular background and clinical development of histone deacetylase and DNA methyltransferase inhibitors
    • Schneider-Stock R., Ocker M., Epigenetic therapy in cancer: molecular background and clinical development of histone deacetylase and DNA methyltransferase inhibitors The Investigational Drugs Journal 2007 10 8 557 561 (Pubitemid 47186508)
    • (2007) IDrugs , vol.10 , Issue.8 , pp. 557-561
    • Scneider-Stock, R.1    Ocker, M.2
  • 82
    • 30644463203 scopus 로고    scopus 로고
    • Microarray analysis of butyrate regulated genes in colonic epithelial cells
    • DOI 10.1089/dna.2006.25.49
    • Daly K., Shirazi-Beechey S. P., Microarray analysis of butyrate regulated genes in colonic epithelial cells DNA and Cell Biology 2006 25 1 49 62 (Pubitemid 43089752)
    • (2006) DNA and Cell Biology , vol.25 , Issue.1 , pp. 49-62
    • Daly, K.1    Shirazi-Beechey, S.P.2
  • 83
    • 1842830815 scopus 로고    scopus 로고
    • Microarray profiling of the effects of histone deacetylase inhibitors on gene expression in cancer cell lines
    • Gray S. G., Qian C. N., Furge K., Guo X., Teh B. T., Microarray profiling of the effects of histone deacetylase inhibitors on gene expression in cancer cell lines International Journal of Oncology 2004 24 4 773 795
    • (2004) International Journal of Oncology , vol.24 , Issue.4 , pp. 773-795
    • Gray, S.G.1    Qian, C.N.2    Furge, K.3    Guo, X.4    Teh, B.T.5
  • 85
    • 0035313803 scopus 로고    scopus 로고
    • Histone acetyltransferases: Function, structure, and catalysis
    • DOI 10.1016/S0959-437X(00)00173-8
    • Marmorstein R., Roth S. Y., Histone acetyltransferases: function, structure, and catalysis Current Opinion in Genetics and Development 2001 11 2 155 161 (Pubitemid 32209199)
    • (2001) Current Opinion in Genetics and Development , vol.11 , Issue.2 , pp. 155-161
    • Marmorstein, R.1    Roth, S.Y.2
  • 86
    • 61849144810 scopus 로고    scopus 로고
    • HDAC family: What are the cancer relevant targets?
    • Witt O., Deubzer H. E., Milde T., Oehme I., HDAC family: what are the cancer relevant targets? Cancer Letters 2009 277 1 8 21
    • (2009) Cancer Letters , vol.277 , Issue.1 , pp. 8-21
    • Witt, O.1    Deubzer, H.E.2    Milde, T.3    Oehme, I.4
  • 87
    • 79959337199 scopus 로고    scopus 로고
    • Deacetylase inhibitorsfocus on non-histone targets and effects
    • Ocker M., Deacetylase inhibitorsfocus on non-histone targets and effects World Journal of Biological Chemistry 2010 1 5 55 61
    • (2010) World Journal of Biological Chemistry , vol.1 , Issue.5 , pp. 55-61
    • Ocker, M.1
  • 88
    • 0037067696 scopus 로고    scopus 로고
    • Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family
    • DOI 10.1074/jbc.M111871200
    • Gao L., Cueto M. A., Asselbergs F., Atadja P., Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family Journal of Biological Chemistry 2002 277 28 25748 25755 (Pubitemid 34951896)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.28 , pp. 25748-25755
    • Gao, L.1    Cueto, M.A.2    Asselbergs, F.3    Atadja, P.4
  • 90
    • 33947301272 scopus 로고    scopus 로고
    • Epigenetic signatures of stem-cell identity
    • DOI 10.1038/nrg2046, PII NRG2046
    • Spivakov M., Fisher A. G., Epigenetic signatures of stem-cell identity Nature Reviews Genetics 2007 8 4 263 271 (Pubitemid 46439288)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.4 , pp. 263-271
    • Spivakov, M.1    Fisher, A.G.2
  • 95
    • 67650090545 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Potential in cancer therapy
    • Marks P. A., Xu W. S., Histone deacetylase inhibitors: potential in cancer therapy Journal of Cellular Biochemistry 2009 107 4 600 608
    • (2009) Journal of Cellular Biochemistry , vol.107 , Issue.4 , pp. 600-608
    • Marks, P.A.1    Xu, W.S.2
  • 96
    • 33846122993 scopus 로고    scopus 로고
    • Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug
    • DOI 10.1038/nbt1272, PII NBT1272
    • Marks P. A., Breslow R., Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug Nature Biotechnology 2007 25 1 84 90 (Pubitemid 46087907)
    • (2007) Nature Biotechnology , vol.25 , Issue.1 , pp. 84-90
    • Marks, P.A.1    Breslow, R.2
  • 98
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • DOI 10.1038/nrc1779
    • Minucci S., Pelicci P. G., Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer Nature Reviews Cancer 2006 6 1 38 51 (Pubitemid 43054973)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.1 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 104
    • 0041347519 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy: Is transcription the primary target?
    • DOI 10.1016/S1535-6108(03)00165-X
    • Johnstone R. W., Licht J. D., Histone deacetylase inhibitors in cancer therapy: is transcription the primary target? Cancer Cell 2003 4 1 13 18 (Pubitemid 36904157)
    • (2003) Cancer Cell , vol.4 , Issue.1 , pp. 13-18
    • Johnstone, R.W.1    Licht, J.D.2
  • 105
    • 77449116892 scopus 로고    scopus 로고
    • Acetylation goes global: The emergence of acetylation biology
    • Norris K. L., Lee J. Y., Yao T. P., Acetylation goes global: the emergence of acetylation biology Science Signaling 2009 2 97 e76
    • (2009) Science Signaling , vol.2 , Issue.97 , pp. 76
    • Norris, K.L.1    Lee, J.Y.2    Yao, T.P.3
  • 107
  • 109
    • 38649092744 scopus 로고    scopus 로고
    • Regulation of protein turnover by acetyltransferases and deacetylases
    • DOI 10.1016/j.biochi.2007.06.009, PII S030090840700168X
    • Sadoul K., Boyault C., Pabion M., Khochbin S., Regulation of protein turnover by acetyltransferases and deacetylases Biochimie 2008 90 2 306 312 (Pubitemid 351172566)
    • (2008) Biochimie , vol.90 , Issue.2 , pp. 306-312
    • Sadoul, K.1    Boyault, C.2    Pabion, M.3    Khochbin, S.4
  • 111
    • 73949128107 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy
    • Lane A. A., Chabner B. A., Histone deacetylase inhibitors in cancer therapy Journal of Clinical Oncology 2009 27 32 5459 5468
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.32 , pp. 5459-5468
    • Lane, A.A.1    Chabner, B.A.2
  • 118
    • 35048856900 scopus 로고    scopus 로고
    • Depsipeptide (FK228) as a novel histone deacetylase inhibitor: Mechanism of action and anticancer activity
    • DOI 10.2174/138955707782110178
    • Lech-Maranda E., Robak E., Korycka A., Robak T., Depsipeptide (FK228) as a novel histone deacetylase inhibitor: mechanism of action and anticancer activity Mini-Reviews in Medicinal Chemistry 2007 7 10 1062 1069 (Pubitemid 47554775)
    • (2007) Mini-Reviews in Medicinal Chemistry , vol.7 , Issue.10 , pp. 1062-1069
    • Lech-Maranda, E.1    Robak, E.2    Korycka, A.3    Robak, T.4
  • 119
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • DOI 10.1126/science.1063127
    • Jenuwein T., Allis C. D., Translating the histone code Science 2001 293 5532 1074 1080 (Pubitemid 32758077)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 122
    • 65649104706 scopus 로고    scopus 로고
    • Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias
    • Figueroa M. E., Melnick A., Greally J. M., Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias Methods in Molecular Biology 2009 538 395 407
    • (2009) Methods in Molecular Biology , vol.538 , pp. 395-407
    • Figueroa, M.E.1    Melnick, A.2    Greally, J.M.3
  • 125
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • Phiel C. J., Zhang F., Huang E. Y., Guenther M. G., Lazar M. A., Klein P. S., Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen Journal of Biological Chemistry 2001 276 39 36734 36741
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.39 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 126
    • 4444309863 scopus 로고    scopus 로고
    • Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid
    • DOI 10.1182/blood-2003-12-4333
    • Kuendgen A., Strupp C., Aivado M., Bernhardt A., Hildebrandt B., Haas R., Germing U., Gattermann N., Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid Blood 2004 104 5 1266 1269 (Pubitemid 39166498)
    • (2004) Blood , vol.104 , Issue.5 , pp. 1266-1269
    • Kuendgen, A.1    Strupp, C.2    Aivado, M.3    Bernhardt, A.4    Hildebrandt, B.5    Haas, R.6    Germing, U.7    Gattermann, N.8
  • 129
    • 0037082488 scopus 로고    scopus 로고
    • Frequent mutations in the ligand-binding domain of PML-RARα after multiple relapses of acute promyelocytic leukemia: Analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo
    • DOI 10.1182/blood.V99.4.1356
    • Zhou D.-C., Kim S. H., Ding W., Schultz C., Warrell Jr. R. P., Gallagher R. E., Frequent mutations in the ligand-binding domain of PML-RAR after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo Blood 2002 99 4 1356 1363 (Pubitemid 34547092)
    • (2002) Blood , vol.99 , Issue.4 , pp. 1356-1363
    • Zhou, D.-C.1    Kim, S.H.2    Ding, W.3    Schultz, C.4    Warrell Jr., R.P.5    Gallagher, R.E.6
  • 130
    • 38949125341 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor (HDI) depsipeptide has differential activity in core binding factor AML
    • Odenike O. M., Alkan S., Sher D., The histone deacetylase inhibitor (HDI) depsipeptide has differential activity in core binding factor AML Blood 2006 108 11 553A
    • (2006) Blood , vol.108 , Issue.11
    • Odenike, O.M.1    Alkan, S.2    Sher, D.3
  • 133
    • 33751177396 scopus 로고    scopus 로고
    • Final results of a phase i study of the histone deacetylase inhibitor vorinostat (suberoyanilide hydroxamic acid, SAHA), in patients with leukemia and myelodysplastic syndrome
    • Garcia-Manero G., Yang H., Sanchez-Gonzalez B., Final results of a phase I study of the histone deacetylase inhibitor vorinostat (suberoyanilide hydroxamic acid, SAHA), in patients with leukemia and myelodysplastic syndrome Blood 2005 106 11 785A
    • (2005) Blood , vol.106 , Issue.11
    • Garcia-Manero, G.1    Yang, H.2    Sanchez-Gonzalez, B.3
  • 135
    • 0033988813 scopus 로고    scopus 로고
    • DNA methyltransferase Dnmt1 associates with histone deacetylase activity
    • DOI 10.1038/71750
    • Fuks F., Burgers W. A., Brehm A., Hughes-Davies L., Kouzarides T., DNA methyltransferase Dnmt1 associates with histone deacetylase activity Nature Genetics 2000 24 1 88 91 (Pubitemid 30041428)
    • (2000) Nature Genetics , vol.24 , Issue.1 , pp. 88-91
    • Fuks, F.1    Burgers, W.A.2    Brehm, A.3    Hughes-Davies, L.4    Kouzarides, T.5
  • 136
    • 0033945861 scopus 로고    scopus 로고
    • DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
    • DOI 10.1038/77023
    • Rountree M. R., Bachman K. E., Baylin S. B., DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci Nature Genetics 2000 25 3 269 277 (Pubitemid 30437311)
    • (2000) Nature Genetics , vol.25 , Issue.3 , pp. 269-277
    • Rountree, M.R.1    Bachman, K.E.2    Baylin, S.B.3
  • 137
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re- expression of genes silenced in cancer
    • DOI 10.1038/5047
    • Cameron E. E., Bachman K. E., Myhnen S., Herman J. G., Baylin S. B., Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer Nature Genetics 1999 21 1 103 107 (Pubitemid 29036293)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 138
    • 0036040215 scopus 로고    scopus 로고
    • Chromatin modification, leukaemia and implications for therapy
    • DOI 10.1046/j.1365-2141.2002.03586.x
    • Jones L. K., Saha V., Chromatin modification, leukaemia and implications for therapy British Journal of Haematology 2002 118 3 714 727 (Pubitemid 35007375)
    • (2002) British Journal of Haematology , vol.118 , Issue.3 , pp. 714-727
    • Jones, L.K.1    Saha, V.2
  • 139
    • 0037115392 scopus 로고    scopus 로고
    • Dependence of histone modifications and gene expression on DNA hypermethylation in cancer
    • Fahrner J. A., Eguchi S., Herman J. G., Baylin S. B., Dependence of histone modifications and gene expression on DNA hypermethylation in cancer Cancer Research 2002 62 24 7213 7218 (Pubitemid 36025241)
    • (2002) Cancer Research , vol.62 , Issue.24 , pp. 7213-7218
    • Fahrner, J.A.1    Eguchi, S.2    Herman, J.G.3    Baylin, S.B.4
  • 140
    • 0037112369 scopus 로고    scopus 로고
    • Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′- deoxycytidine
    • Nguyen C. T., Weisenberger D. J., Velicescu M., Gonzales F. A., Lin J. C. Y., Liang G., Jones P. A., Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′-deoxycytidine Cancer Research 2002 62 22 6456 6461 (Pubitemid 35364106)
    • (2002) Cancer Research , vol.62 , Issue.22 , pp. 6456-6461
    • Nguyen, C.T.1    Weisenberger, D.J.2    Velicescu, M.3    Gonzales, F.A.4    Lin, J.C.Y.5    Liang6
  • 141
    • 33845943192 scopus 로고    scopus 로고
    • Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models
    • DOI 10.1080/00365520600874198, PII H32M860MJ981H000
    • Neureiter D., Zopf S., Leu T., Dietze O., Hauser-Kronberger C., Hahn E. G., Herold C., Ocker M., Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models Scandinavian Journal of Gastroenterology 2007 42 1 103 116 (Pubitemid 46033053)
    • (2007) Scandinavian Journal of Gastroenterology , vol.42 , Issue.1 , pp. 103-116
    • Neureiter, D.1    Zopf, S.2    Leu, T.3    Dietze, O.4    Hauser-Kronberger, C.5    Hahn, E.G.6    Herold, C.7    Ocker, M.8
  • 147
    • 31444438952 scopus 로고    scopus 로고
    • Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome
    • DOI 10.1038/sj.leu.2404050, PII 2404050
    • Maslak P., Chanel S., Camacho L. H., Soignet S., Pandolfi P. P., Guernah I., Warrell R., Nimer S., Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome Leukemia 2006 20 2 212 217 (Pubitemid 43148657)
    • (2006) Leukemia , vol.20 , Issue.2 , pp. 212-217
    • Maslak, P.1    Chanel, S.2    Camacho, L.H.3    Soignet, S.4    Pandolfi, P.P.5    Guernah, I.6    Warrell, R.7    Nimer, S.8
  • 148
    • 33644814867 scopus 로고    scopus 로고
    • Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: Relevance to mechanism of therapeutic action
    • Zhang C., Richon V., Ni X., Talpur R., Duvic M., Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action Journal of Investigative Dermatology 2005 125 5 1045 1052
    • (2005) Journal of Investigative Dermatology , vol.125 , Issue.5 , pp. 1045-1052
    • Zhang, C.1    Richon, V.2    Ni, X.3    Talpur, R.4    Duvic, M.5
  • 149
    • 50049108874 scopus 로고    scopus 로고
    • Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma
    • Marquard L., Gjerdrum L. M., Christensen I. J., Jensen P. B., Sehested M., Ralfkiaer E., Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma Histopathology 2008 53 3 267 277
    • (2008) Histopathology , vol.53 , Issue.3 , pp. 267-277
    • Marquard, L.1    Gjerdrum, L.M.2    Christensen, I.J.3    Jensen, P.B.4    Sehested, M.5    Ralfkiaer, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.