-
2
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti, F., and Dobson, C. M. (2006) Protein misfolding, functional amyloid, and human disease. Annu. Rev. Biochem. 75, 333-366.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
3
-
-
33845637320
-
From the polymorphism of amyloid fibrils to their assembly mechanism and cytotoxicity
-
Kreplak, L., and Aebi, U. (2006) From the polymorphism of amyloid fibrils to their assembly mechanism and cytotoxicity. Adv. Protein Chem. 73, 217-233.
-
(2006)
Adv. Protein Chem.
, vol.73
, pp. 217-233
-
-
Kreplak, L.1
Aebi, U.2
-
4
-
-
3943084181
-
Emerging principles of conformation-based prion inheritance
-
Chien, P., Weissman, J. S., and DePace, A. H. (2004) Emerging principles of conformation-based prion inheritance. Annu. Rev. Biochem. 73, 617-656.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 617-656
-
-
Chien, P.1
Weissman, J.S.2
DePace, A.H.3
-
5
-
-
33846160381
-
Polymorphism in the intermediates and products of amyloid assembly
-
Kodali, R., and Wetzel, R. (2007) Polymorphism in the intermediates and products of amyloid assembly. Curr. Opin. Struct. Biol. 17, 48-57.
-
(2007)
Curr. Opin. Struct. Biol.
, vol.17
, pp. 48-57
-
-
Kodali, R.1
Wetzel, R.2
-
6
-
-
33846126930
-
Plasticity of amyloid fibrils
-
Wetzel, R., Shivaprasad, S., and Williams, A. D. (2007) Plasticity of amyloid fibrils. Biochemistry 46, 1-10.
-
(2007)
Biochemistry
, vol.46
, pp. 1-10
-
-
Wetzel, R.1
Shivaprasad, S.2
Williams, A.D.3
-
7
-
-
33744954409
-
Probing the conformation of the prion protein within a single amyloid fibril using a novel immunoconformational assay
-
Novitskaya, V.,Makarava, N.,Bellon, A., Bocharova, O.V.,Bronstein, I. B., Williamson, R. A., and Baskakov, I. V. (2006) Probing the conformation of the prion protein within a single amyloid fibril using a novel immunoconformational assay. J. Biol. Chem. 281, 15536-15545.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15536-15545
-
-
Novitskaya, V.1
Makarava, N.2
Bellon, A.3
Bocharova, O.V.4
Bronstein, I.B.5
Williamson, R.A.6
Baskakov, I.V.7
-
8
-
-
67649365665
-
Parkinson's disease: The syndrome, the pathogenesis and pathophysiology
-
doi 10.1016/j.cortex.2008.11.010
-
Bartels, A. L., and Leenders, K. L. (2008) Parkinson's disease: The syndrome, the pathogenesis and pathophysiology. Cortex (doi 10.1016/j.cortex. 2008.11.010).
-
(2008)
Cortex
-
-
Bartels, A.L.1
Leenders, K.L.2
-
10
-
-
34548620297
-
Neuropathology, biochemistry, and biophysics of α-synuclein aggregation
-
Uversky, V. N. (2007) Neuropathology, biochemistry, and biophysics of α-synuclein aggregation. J. Neurochem. 103, 17-37.
-
(2007)
J. Neurochem.
, vol.103
, pp. 17-37
-
-
Uversky, V.N.1
-
11
-
-
13444252277
-
Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein
-
Bertoncini, C. W., Jung, Y. S., Fernandez, C. O., Hoyer, W., Griesinger, C., Jovin, T. M., and Zweckstetter, M. (2005) Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein. Proc. Natl. Acad. Sci. U.S.A. 102, 1430-1435.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 1430-1435
-
-
Bertoncini, C.W.1
Jung, Y.S.2
Fernandez, C.O.3
Hoyer, W.4
Griesinger, C.5
Jovin, T.M.6
Zweckstetter, M.7
-
12
-
-
24744461907
-
Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation
-
Bertoncini, C. W., Fernandez, C. O., Griesinger, C., Jovin, T. M., and Zweckstetter, M. (2005) Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation. J. Biol. Chem. 280, 30649-30652.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 30649-30652
-
-
Bertoncini, C.W.1
Fernandez, C.O.2
Griesinger, C.3
Jovin, T.M.4
Zweckstetter, M.5
-
13
-
-
0034712918
-
Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation
-
Serpell, L. C., Berriman, J., Jakes, R., Goedert, M., and Crowther, R. A. (2000) Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation. Proc. Natl. Acad. Sci. U.S.A. 97, 4897-4902.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 4897-4902
-
-
Serpell, L.C.1
Berriman, J.2
Jakes, R.3
Goedert, M.4
Crowther, R.A.5
-
14
-
-
34548359337
-
Investigation of α-synuclein fibril structure by site-directed spin labeling
-
Chen, M., Margittai, M., Chen, J., and Langen, R. (2007) Investigation of α-synuclein fibril structure by site-directed spin labeling. J. Biol. Chem. 282, 24970-24979.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24970-24979
-
-
Chen, M.1
Margittai, M.2
Chen, J.3
Langen, R.4
-
15
-
-
27644518721
-
Molecular-level secondary structure, polymorphism, and dynamics of full-length α-synuclein fibrils studied by solidstate NMR
-
Heise, H., Hoyer, W., Becker, S., Andronesi, O. C., Riedel, D., and Baldus, M. (2005) Molecular-level secondary structure, polymorphism, and dynamics of full-length α-synuclein fibrils studied by solidstate NMR. Proc. Natl. Acad. Sci. U.S.A. 102, 15871-15876.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 15871-15876
-
-
Heise, H.1
Hoyer, W.2
Becker, S.3
Andronesi, O.C.4
Riedel, D.5
Baldus, M.6
-
16
-
-
47249110199
-
The fold of α-synuclein fibrils
-
Vilar, M., Chou, H. T., Luhrs, T., Maji, S. K., Riek-Loher, D., Verel, R., Manning, G., Stahlberg, H., and Riek, R. (2008) The fold of α-synuclein fibrils. Proc. Natl. Acad. Sci. U.S.A. 105, 8637-8642.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 8637-8642
-
-
Vilar, M.1
Chou, H.T.2
Luhrs, T.3
Maji, S.K.4
Riek-Loher, D.5
Verel, R.6
Manning, G.7
Stahlberg, H.8
Riek, R.9
-
17
-
-
0036386364
-
Dependence of α-synuclein aggregate morphology on solution conditions
-
Hoyer, W., Antony, T., Cherny, D., Heim, G., Jovin, T. M., and Subramaniam, V. (2002) Dependence of α-synuclein aggregate morphology on solution conditions. J. Mol. Biol. 322, 383-393.
-
(2002)
J. Mol. Biol.
, vol.322
, pp. 383-393
-
-
Hoyer, W.1
Antony, T.2
Cherny, D.3
Heim, G.4
Jovin, T.M.5
Subramaniam, V.6
-
18
-
-
0033583215
-
Mutant and wild type human α-synucleins assemble into elongated filaments with distinct morphologies in vitro
-
Giasson, B. I., Uryu, K., Trojanowski, J. Q., and Lee, V. M. (1999) Mutant and wild type human α-synucleins assemble into elongated filaments with distinct morphologies in vitro. J. Biol. Chem. 274, 7619-7622.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7619-7622
-
-
Giasson, B.I.1
Uryu, K.2
Trojanowski, J.Q.3
Lee, V.M.4
-
19
-
-
33845358566
-
Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from α-synuclein mutants
-
van Raaij, M. E., Segers-Nolten, I. M., and Subramaniam, V. (2006) Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from α-synuclein mutants. Biophys. J. 91, L96-L98.
-
(2006)
Biophys. J.
, vol.91
-
-
Van Raaij, M.E.1
Segers-Nolten, I.M.2
Subramaniam, V.3
-
20
-
-
65549150887
-
Conversion of wild-type α-synuclein into mutant-type fibrils and its propagation in the presence of A30P mutant
-
Yonetani, M., Nonaka, T., Masuda, M., Inukai, Y., Oikawa, T., Hisanaga, S. I., and Hasegawa, M. (2009) Conversion of wild-type α-synuclein into mutant-type fibrils and its propagation in the presence of A30P mutant. J. Biol. Chem. 284, 7940-7950.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 7940-7950
-
-
Yonetani, M.1
Nonaka, T.2
Masuda, M.3
Inukai, Y.4
Oikawa, T.5
Hisanaga, S.I.6
Hasegawa, M.7
-
21
-
-
33646878753
-
Preparation of α-synuclein fibrils for solidstateNMR: Expression, purification, and incubation of wild-type and mutant forms
-
Kloepper, K. D., Woods, W. S., Winter, K. A., George, J. M., and Rienstra, C. M. (2006) Preparation of α-synuclein fibrils for solidstateNMR: Expression, purification, and incubation of wild-type and mutant forms. Protein Expression Purif. 48, 112-117.
-
(2006)
Protein Expression Purif.
, vol.48
, pp. 112-117
-
-
Kloepper, K.D.1
Woods, W.S.2
Winter, K.A.3
George, J.M.4
Rienstra, C.M.5
-
22
-
-
51749125627
-
Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant α-synuclein
-
Heise, H., Celej, M. S., Becker, S., Riedel, D., Pelah, A., Kumar, A., Jovin, T. M., and Baldus, M. (2008) Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant α-synuclein. J. Mol. Biol. 380, 444-450.
-
(2008)
J. Mol. Biol.
, vol.380
, pp. 444-450
-
-
Heise, H.1
Celej, M.S.2
Becker, S.3
Riedel, D.4
Pelah, A.5
Kumar, A.6
Jovin, T.M.7
Baldus, M.8
-
23
-
-
45849128342
-
Fluorescent N-arylaminonaphthalene sulfonate probes for amyloid aggregation of α-synuclein
-
Celej,M. S., Jares-Erijman, E. A., and Jovin, T.M. (2008) Fluorescent N-arylaminonaphthalene sulfonate probes for amyloid aggregation of α-synuclein. Biophys. J. 94, 4867-4879.
-
(2008)
Biophys. J.
, vol.94
, pp. 4867-4879
-
-
Celej, M.S.1
Jares-Erijman, E.A.2
Jovin, T.M.3
-
24
-
-
42649135877
-
Multiparametric fluorescence detection of early stages in the amyloid protein aggregation of pyrene-labeled α-synuclein
-
Thirunavukkuarasu, S., Jares-Erijman, E. A., and Jovin, T. M. (2008) Multiparametric fluorescence detection of early stages in the amyloid protein aggregation of pyrene-labeled α-synuclein. J. Mol. Biol. 378, 1064-1073.
-
(2008)
J. Mol. Biol.
, vol.378
, pp. 1064-1073
-
-
Thirunavukkuarasu, S.1
Jares-Erijman, E.A.2
Jovin, T.M.3
-
25
-
-
0142125377
-
Modulation of the solvent-dependent dual emission in 3-hydroxychromone by substituents
-
Klymchenko, A. S., Pivovarenko, V. G., Ozturk, T., and Demchenko, A. P. (2003) Modulation of the solvent-dependent dual emission in 3-hydroxychromone by substituents. New J. Chem. 27, 1336-1343.
-
(2003)
New J. Chem.
, vol.27
, pp. 1336-1343
-
-
Klymchenko, A.S.1
Pivovarenko, V.G.2
Ozturk, T.3
Demchenko, A.P.4
-
26
-
-
0037208160
-
Multiparametric probing of intermolecular interactions with fluorescent dye exhibiting excited state intramolecular proton transfer
-
Klymchenko, A. S., and Demchenko, A. P. (2003) Multiparametric probing of intermolecular interactions with fluorescent dye exhibiting excited state intramolecular proton transfer. Phys. Chem. Chem. Phys. 5, 461-468.
-
(2003)
Phys. Chem. Chem. Phys.
, vol.5
, pp. 461-468
-
-
Klymchenko, A.S.1
Demchenko, A.P.2
-
27
-
-
6344287943
-
Dynamics of intermolecular hydrogen bonds in the excited states of 4-dialkylamino-3-hydroxyflavones. On the pathway to an ideal fluorescent hydrogen bonding sensor
-
Shynkar, V. V.,Klymchenko, A. S., Piémont, E., Demchenko, A. P., and Mély, Y. (2004) Dynamics of intermolecular hydrogen bonds in the excited states of 4-dialkylamino-3-hydroxyflavones. On the pathway to an ideal fluorescent hydrogen bonding sensor. J. Phys. Chem. A 108, 8151-8159.
-
(2004)
J. Phys. Chem.
, vol.108
, pp. 8151-8159
-
-
Shynkar, V.V.1
Klymchenko, A.S.2
Piémont, E.3
Demchenko, A.P.4
Mély, Y.5
-
28
-
-
2142812408
-
Bimodal Distribution and Fluorescence Response of Environment-Sensitive Probes in Lipid Bilayers
-
Klymchenko, A. S., Duportail, G., Demchenko, A. P., and Mely, Y. (2004) Bimodal distribution and fluorescence response of environment- sensitive probes in lipid bilayers. Biophys. J. 86, 2929-2941. (Pubitemid 38552697)
-
(2004)
Biophysical Journal
, vol.86
, Issue.5
, pp. 2929-2941
-
-
Klymchenko, A.S.1
Duportail, G.2
Demchenko, A.P.3
Mely, Y.4
-
29
-
-
0029904487
-
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
-
Weinreb, P. H., Zhen, W., Poon, A.W., Conway, K.A., and Lansbury, P. T., Jr. (1996)NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35, 13709-13715.
-
(1996)
Biochemistry
, vol.35
, pp. 13709-13715
-
-
Weinreb, P.H.1
Zhen, W.2
Poon, A.W.3
Conway, K.A.4
Lansbury Jr., P.T.5
-
30
-
-
36849108026
-
Band shapes of the electronic spectra of complex molecules
-
Siano, D. B., and Metzler, D. E. (1969) Band shapes of the electronic spectra of complex molecules. J. Chem. Phys. 51, 1856-1861.
-
(1969)
J. Chem. Phys.
, vol.51
, pp. 1856-1861
-
-
Siano, D.B.1
Metzler, D.E.2
-
31
-
-
0036363969
-
The red-edge effects: 30 years of exploration
-
Demchenko, A. P. (2002) The red-edge effects: 30 years of exploration. Luminescence 17, 19-42.
-
(2002)
Luminescence
, vol.17
, pp. 19-42
-
-
Demchenko, A.P.1
-
32
-
-
4644251757
-
Simultaneous probing of hydration and polarity of lipid bilayers with 3-hydroxyflavone fluorescent dyes
-
Klymchenko, A. S., Mely, Y., Demchenko, A. P., and Duportail, G. (2004) Simultaneous probing of hydration and polarity of lipid bilayers with 3-hydroxyflavone fluorescent dyes. Biochim. Biophys. Acta 1665, 6-19.
-
(2004)
Biochim. Biophys. Acta
, vol.1665
, pp. 6-19
-
-
Klymchenko, A.S.1
Mely, Y.2
Demchenko, A.P.3
Duportail, G.4
-
33
-
-
0037031232
-
Ultrasensitive fluorescent probe for the hydrophobic range of solvent polarities
-
Ercelen, S., Klymchenko, A. S., and Demchenko, A. P. (2002) Ultrasensitive fluorescent probe for the hydrophobic range of solvent polarities. Anal. Chim. Acta 464, 273-287.
-
(2002)
Anal. Chim. Acta
, vol.464
, pp. 273-287
-
-
Ercelen, S.1
Klymchenko, A.S.2
Demchenko, A.P.3
-
34
-
-
0004177513
-
-
Royal Society of Chemistry, Cambridge, U.K.
-
Suppan, P., and Ghoneim, N. (1997) Solvatochromism, Royal Society of Chemistry, Cambridge, U.K.
-
(1997)
Solvatochromism
-
-
Suppan, P.1
Ghoneim, N.2
-
35
-
-
0037434886
-
Novel two-color fluorescence probe with extreme specificity to bovine serum albumin
-
DOI 10.1016/S0014-5793(03)00116-9
-
Ercelen, S., Klymchenko, A. S., and Demchenko, A. P. (2003) Novel two-color fluorescence probe with extreme specificity to bovine serum albumin. FEBS Lett. 538, 25-28. (Pubitemid 36287419)
-
(2003)
FEBS Letters
, vol.538
, Issue.1-3
, pp. 25-28
-
-
Ercelen, S.1
Klymchenko, A.S.2
Demchenko, A.P.3
-
36
-
-
0043194011
-
Dissociation of amyloid fibrils of α-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities
-
Foguel, D., Suarez, M. C., Ferrao-Gonzales, A. D., Porto, T. C., Palmieri, L., Einsiedler, C. M., Andrade, L. R., Lashuel, H. A., Lansbury, P. T., Kelly, J. W., and Silva, J. L. (2003) Dissociation of amyloid fibrils of α-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities. Proc. Natl. Acad. Sci. U.S.A. 100, 9831-9836.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 9831-9836
-
-
Foguel, D.1
Suarez, M.C.2
Ferrao-Gonzales, A.D.3
Porto, T.C.4
Palmieri, L.5
Einsiedler, C.M.6
Andrade, L.R.7
Lashuel, H.A.8
Lansbury, P.T.9
Kelly, J.W.10
Silva, J.L.11
-
37
-
-
24644500617
-
Main-chain dominated amyloid structures demonstrated by the effect of high pressure
-
Chatani, E., Kato, M., Kawai, T., Naiki, H., and Goto, Y. (2005) Main-chain dominated amyloid structures demonstrated by the effect of high pressure. J. Mol. Biol. 352, 941-951.
-
(2005)
J. Mol. Biol.
, vol.352
, pp. 941-951
-
-
Chatani, E.1
Kato, M.2
Kawai, T.3
Naiki, H.4
Goto, Y.5
-
38
-
-
0035949542
-
Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein
-
DOI 10.1021/bi010616g
-
Li, J., Uversky, V. N., and Fink, A. L. (2001) Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein. Biochemistry 40, 11604-11613. (Pubitemid 32911305)
-
(2001)
Biochemistry
, vol.40
, Issue.38
, pp. 11604-11613
-
-
Li, J.1
Uversky, V.N.2
Fink, A.L.3
-
39
-
-
11144222595
-
The binding of thioflavin-T to amyloid fibrils: Localisation and implications
-
Krebs, M. R., Bromley, E. H., and Donald, A. M. (2005) The binding of thioflavin-T to amyloid fibrils: Localisation and implications. J. Struct. Biol. 149, 30-37.
-
(2005)
J. Struct. Biol.
, vol.149
, pp. 30-37
-
-
Krebs, M.R.1
Bromley, E.H.2
Donald, A.M.3
-
40
-
-
58149326746
-
Molecular mechanism of thioflavin-T binding to the surface of β-rich peptide self-assemblies
-
Biancalana, M., Makabe, K., Koide, A., and Koide, S. (2009) Molecular mechanism of thioflavin-T binding to the surface of β-rich peptide self-assemblies. J. Mol. Biol. 385, 1052-1063.
-
(2009)
J. Mol. Biol.
, vol.385
, pp. 1052-1063
-
-
Biancalana, M.1
Makabe, K.2
Koide, A.3
Koide, S.4
-
41
-
-
38849135987
-
Specific fluorescent detection of fibrillar α-synuclein using mono- And trimethine cyanine dyes
-
Volkova, K. D., Kovalska, V. B., Balanda, A. O., Losytskyy, M. Y., Golub, A.G., Vermeij, R. J., Subramaniam, V., Tolmachev, O. I., and Yarmoluk, S. M. (2008) Specific fluorescent detection of fibrillar α-synuclein using mono- and trimethine cyanine dyes. Bioorg. Med. Chem. 16, 1452-1459.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 1452-1459
-
-
Volkova, K.D.1
Kovalska, V.B.2
Balanda, A.O.3
Losytskyy, M.Y.4
Golub, A.G.5
Vermeij, R.J.6
Subramaniam, V.7
Tolmachev, O.I.8
Yarmoluk, S.M.9
-
42
-
-
59049099079
-
A comprehensive model for packing and hydration for amyloid fibrils of β2-microglobulin
-
Lee, Y. H., Chatani, E., Sasahara, K., Naiki, H., and Goto, Y. (2009) A comprehensive model for packing and hydration for amyloid fibrils of β2-microglobulin. J. Biol. Chem. 284, 2169-2175.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 2169-2175
-
-
Lee, Y.H.1
Chatani, E.2
Sasahara, K.3
Naiki, H.4
Goto, Y.5
-
43
-
-
33847405723
-
Cubic equation governing the outerregion dielectric constant of globular proteins
-
Park, H., and Jeon, Y. H. (2007) Cubic equation governing the outerregion dielectric constant of globular proteins. Phys. Rev. E 75, 021916.
-
(2007)
Phys. Rev. E
, vol.75
, pp. 021916
-
-
Park, H.1
Jeon, Y.H.2
|