TCR transfer induces TCR-mediated tonic inhibition of RAG genes in human T cells

Molecular Immunology

Volumn 48, Issue 12-13, 2011, Pages 1369-1376

  Orlando, Luca ^a   Accomasso, Lisa ^a   Circosta, Paola ^a   Turinetto, Valentina ^a   Lantelme, Erica ^a   Porcedda, Paola ^a,b   Minieri, Valentina ^a   Pautasso, Marisa ^c   Willemsen, Ralph A ^d   Cignetti, Alessandro ^a,e   Giachino, Claudia ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b ISTITUTO NAZIONALE DI RICERCA METROLOGICA   (Italy)

^c SAN LUIGI GONZAGA UNIVERSITY HOSPITAL   (Italy)

^d JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^e MAURIZIANO HOSPITAL   (Italy)

Author keywords

RAG; T cell; TCR transfer; Tonic TCR signaling

Indexed keywords

RAG1 PROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ARTICLE; CHILD; CONTROLLED STUDY; DOWN REGULATION; GENE LOCUS; HUMAN; HUMAN CELL; LENTIVIRINAE; PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VIRAL GENE DELIVERY SYSTEM;

CELL LINE; CELL MEMBRANE; CHILD; DIMETHYL SULFOXIDE; DNA-BINDING PROTEINS; DOWN-REGULATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENES, RAG-1; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOBLOTTING; JURKAT CELLS; LIGANDS; NUCLEAR PROTEINS; PIPERAZINES; PYRIMIDINES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TACROLIMUS; TRANSDUCTION, GENETIC;

EID: 79957924323     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2011.02.015     Document Type: Article

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