The Src-selective kinase inhibitor PP1 also inhibits kit and Bcr-Abl tyrosine kinases

Journal of Biological Chemistry

Volumn 278, Issue 7, 2003, Pages 4847-4853

  Tatton, Louise ^a   Morley, Gary M ^a   Chopra, Rajesh ^b   Khwaja, Asim ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SIGNALING PATHWAYS;

BIOASSAY; CATALYST ACTIVITY; CELLS; ENZYMES; SIGNALING;

BIOCHEMISTRY;

4 AMINO 5 (4 METHYLPHENYL) 7 (BUTYL)PYRAZOLO[3,4 D]PYRIMIDINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; BCR ABL PROTEIN; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; PYRIMIDINE DERIVATIVE; STEM CELL FACTOR; UNCLASSIFIED DRUG; 4 AMINO 5 (4 METHYLPHENYL) 7 (TERT BUTYL)PYRAZOLO(3,4 D)PYRIMIDINE; 4-AMINO-5-(4-METHYLPHENYL)-7-(TERT-BUTYL)PYRAZOLO(3,4-D)PYRIMIDINE; BCR ABL TYROSINE KINASE; BCR-ABL TYROSINE KINASE; ENZYME INHIBITOR; PYRAZOLE DERIVATIVE; STEM CELL FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHOSPHORYLATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; IMMUNOPRECIPITATION; LEUKEMIA; MAST CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; MUTATION;

ANIMALIA;

ANIMALS; CELL LINE; ENZYME INHIBITORS; MUTATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-KIT; PYRAZOLES; PYRIMIDINES; RATS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 0038813693     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209321200     Document Type: Article

References (43)

1. Hanke, J. H., Gardner, J. P., Dow, R. L., Changelian, P. S., Brissette, W. H., Weringer, E. J., Pollok, B. A., and Connelly, P. A. (1996) J. Biol. Chem. 271, 695-701
2. Amoui, M., Draber, P., and Draberova, L. (1997) Eur. J. Immunol. 27, 1881-1886
3. Linnekin, D., DeBerry, C. S., and Mou, S. (1997) J. Biol. Chem. 272, 27450-27455
4. Broudy, V. C., Lin, N. L., Liles, W. C., Corey, S. J., O'Laughlin, B., Mou, S., and Linnekin, D. (1999) Blood 94, 1979-1986
5. Abassi, Y. A., Carroll, D. J., Giusti, A. F., Belton, R. J., and Foltz, K. R. (2000) Dev. Biol. 218, 206-219
6. Dahl, M. E., Arai, K. I., and Watanabe, S. (2000) Genes Cells 5, 143-153
7. Mocsai, A., Ligeti, E., Lowell, C. A., and Berton, G. (1999) J. Immunol. 162, 1120-1126
8. Krystal, G. W., DeBerry, C. S., Linnekin, D., and Litz, J. (1998) Cancer Res. 58, 4660-4666
9. Broudy, V. C. (1997) Blood 90, 1345-1364
10. Ashman, L. K. (1999) Int. J. Biochem. Cell Biol. 31, 1037-1051
11. Nocka, K., Majumder, S., Chabot, B., Ray, P., Cervone, M., Bernstein, A., and Besmer, P. (1989) Genes Dev. 3, 816-826
12. Valent, P., Escribano, L., Parwaresch, R. M., Schemmel, V., Schwartz, L. B., Sotlar, K., Sperr, W. R., and Horny, H. P. (1999) Int. Arch. Allergy Appl. Immunol. 120, 1-7
13. Hirota, S., Isozaki, K., Moriyama, Y., Hashimoto, K., Nishida, T., Ishiguro, S., Kawano, K., Hanada, M., Kurata, A., Takeda, M., Muhammad Tunio, G., Matsuzawa, Y., Kanakura, Y., Shinomura, Y., and Kitamura, Y. (1998) Science 279, 577-580
14. Amundadottir, L. T., and Leder, P. (1998) Oncogene 16, 737-746
15. Hines, S. J., Litz, J. S., and Krystal, G. W. (1999) Breast Cancer Res. Treat. 58, 1-10
16. Krystal, G. W., Hines, S. J., and Organ, C. P. (1996) Cancer Res. 56, 370-376
17. Boissan, M., Feger, F., Guillosson, J. J., and Arock, M. (2000) J. Leukoc. Biol. 67, 135-148
18. Morita, Y., and Siraganian, R. P. (1981) J. Immunol. 127, 1339-1344
19. Avanzi, G. C., Lista, P., Giovinazzo, B., Miniero, R., Saglio, G., Benetton, G., Coda, R., Cattoretti, G., and Pegoraro, L. (1988) Br. J Haematol 69, 359-366
20. Cambier, N., Chopra, R., Strasser, A., Metcalf, D., and Elefanty, A. G. (1998) Oncogene 16, 335-348
21. Price, D. J., Rivnay, B., and Avraham, H. (1999) Biochem. Biophys. Res. Commun. 259, 611-616
22. Blake, R. A., Broome, M. A., Liu, X., Wu, J., Gishizky, M., Sun, L., and Courtneidge, S. A. (2000) Mol. Cell. Biol. 20, 9018-9027
23. Bowman, T., Broome, M. A., Sinibaldi, D., Wharton, W., Pledger, W. J., Sedivy, J. M., Irby, R., Yeatman, T., Courtneidge, S. A., and Jove, R. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 7319-7324
24. Buchdunger, E., Cioffi, C. L., Law, N., Stover, D., Ohno-Jones, S., Druker, B. J., and Lydon, N. B. (2000) J. Pharmacol, Exp. Ther 295, 139-145
25. Heinrich, M. C., Griffith, D. J., Druker, B. J., Wait, C. L., Ott, K. A., and Zigler, A. J. (2000) Blood 96, 925-932
26. Ma, Y., Carter, E., Wang, X., Shu, C., McMahon, G., and Longley, B. J. (2000) J. Invest. Dermatol. 114, 392-394
27. Ma, Y., Zeng, S., Metcalfe, D. D., Akin, C., Dimitrijevic, S., Butterfield, J. H., McMahon, G., and Longley, B. J. (2002) Blood 99, 1741-1744
28. Tsujimura, T., Furitsu, T., Morimoto, M., Kanayama, Y., Nomura, S., Matsuzawa, Y., Kitamura, Y., and Kanakura, Y. (1995) Int. Arch. Allergy Appl. Immunol. 106, 377-385
29. Waltenberger, J., Uecker, A., Kroll, J., Frank, H., Mayr, U., Bjorge, J. D., Fujita, D., Gazit, A., Hombach, V., Levitzki, A., and Bohmer, F. D. (1999) Circ. Res. 85, 12-22
30. Carlomagno, F., Vitagliano, D., Guida, T., Napolitano, M., Vecchio, G., Fusco, A., Gazit, A., Levitzki, A., and Santoro, M. (2002) Cancer Res. 62, 1077-1082
31. Bondzi, C., Litz, J., Dent, P., and Krystal, G. W. (2000) Cell Growth Differ. 11, 305-314
32. Mou, S., and Linnekin, D. (1999) Biochem. J. 342, 163-170
33. Longley, B. J., Metcalfe, D. D., Tharp, M., Wang, X., Tyrrell, L., Lu, S. Z., Heitjan, D., and Ma, Y. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1609-1614
34. Furitsu, T., Tsujimura, T., Tono, T., Ikeda, H., Kitayama, H., Koshimizu, U., Sugahara, H., Butterfield, J. H., Ashman, L. K., Kanayama, Y., Matsuzawa, Y., and Kanakura, Y. (1993) J. Clin. Invest. 92, 1736-1744
35. Nagata, H., Okada, T., Worobec, A. S., Semere, T., and Metcalfe, D. D. (1997) Int. Arch. Allergy Appl. Immunol. 113, 184-186
36. Buttner, C., Henz, B. M., Welker, P., Sepp, N. T., and Grabbe, J. (1998) J Investig. Dermatol 111, 1227-1231
37. Kilic, T., Alberta, J. A., Zdunek, P. R., Acar, M., Iannarelli, P., O'Reilly, T., Buchdunger, E., Black, P. M., and Stiles, C. D. (2000) Cancer Res. 60, 5143-5150
38. Mahon, F. X., Deininger, M. W., Schultheis, B., Chabrol, J., Reiffers, J., Goldman, J. M., and Melo, J. V. (2000) Blood 96, 1070-1079
39. Weisberg, E., and Griffin, J. D. (2000) Blood 95, 3498-3505
40. Branford, S., Rudzki, Z., Walsh, S., Grigg, A., Arthur, C., Taylor, K., Herrmann, R., Lynch, K. P., and Hughes, T. P. (2002) Blood 99, 3472-3475
41. Druker, B. J. (2002) Cancer Cell 1, 31-36
42. Gambacorti-Passerini, C., Barni, R., le Coutre, P., Zucchetti, M., Cabrita, G., Cleris, L., Rossi, F., Gianazza, E., Brueggen, J., Cozens, R., Pioltelli, P., Pogliani, E., Corneo, G., Formelli, F., and D'Incalci, M. (2000) J. Natl. Cancer Inst. 92, 1641-1650
43. Liu, Y., Bishop, A., Witucki, L., Kraybill, B., Shimizu, E., Tsien, J., Ubersax, J., Blethrow, J., Morgan, D. O., and Shokat, K. M. (1999) Chem. Biol. 6, 671-678