Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm

Journal of Biology

Volumn 3, Issue 3, 2004, Pages

  Okubo, Tadashi ^a   Hogan, Brigid L M ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; LYMPHOID ENHANCER FACTOR 1; SURFACTANT PROTEIN C; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ATOH1; TRANSCRIPTION FACTOR CDX1; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL PROLIFERATION; CUBOIDAL EPITHELIUM CELL; DNA MICROARRAY; EMBRYO; EMBRYO DEVELOPMENT; ENDODERM; EPITHELIUM CELL; GENE DELETION; GENE EXPRESSION; GOBLET CELL; IN SITU HYBRIDIZATION; INTESTINE METAPLASIA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PANETH CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENIC MOUSE; UNINDEXED SEQUENCE;

ANIMALS; CELL LINEAGE; ENDODERM; EPITHELIUM; GASTROINTESTINAL TRACT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES; INTESTINES; LUNG; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; MICROARRAY ANALYSIS; ORGAN SPECIFICITY; PHENOTYPE; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TRANSGENES; WNT PROTEINS;

ANIMALIA; MUS MUSCULUS;

EID: 3042840059     PISSN: 14785854     EISSN: 14754924     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Wild CP, Hardie LJ: Reflux, Barrett's oesophagus and adenocarcinoma: burning questions. Nat Rev Cancer 2003, 3:676-684.
2. Yuasa Y: Control of gut differentiation and intestinal-type gastric carcinogenesis. Nat Rev Cancer 2003, 3:592-600.
3. Tosh D, Slack JM. How cells change their phenotype. Nat Rev Mol Cell Biol 2002, 3:187-194.
4. Slack JM, Tosh D: Transdifferentiation and metaplasia - switching cell types. Curr Opin Genet Dev 2001, 11:581-586.
5. The Wnt gene homepage [http://www.stanford.edu/~rnusse/wntwindow.html].
6. Maves L, Schubiger G: Transdetermination in Drosophila imaginal discs: a model for understanding pluripotency and selector gene maintenance. Curr Opin Genet Dev 2003, 13:472-479.
7. Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H: Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 1998, 19:379-383.
8. Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY: Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 2001, 294:2155-2158.
9. Pinto D, Gregorieff A, Begthel H, Clevers H: Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev 2003, 17:1709-1713.
10. Cardoso WV: Lung morphogenesis revisited: old facts, current ideas. Dev Dyn 2000, 219:121-130.
11. Warburton D, Schwarz M, Tefft D, Flores-Delgado G, Anderson KD, Cardoso WV: The molecular basis of lung morphogenesis. Mech Dev 2000, 92:55-81.
12. Borges M, Linnoila RI, van de Velde HJ, Chen H, Nelkin BD, Mabry M, Baylin SB, Ball DW: An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Nature 1997, 386:852-855.
13. Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H: Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development 2000, 127:3913-3921.
14. Tebar M, Destree O, de Vree WJ, Ten Have-Opbroek AA: Expression of Tcf/Lef and sFrp and localization of β-catenin in the developing mouse lung. Mech Dev 2001, 109:437-440.
15. Weidenfeld J, Shu W, Zhang L, Millar SE, Morrisey EE: The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium. J Biol Chem 2002, 277:21061-21070.
16. Duan D, Yue Y, Zhou W, Labed B, Ritchie TC, Grosschedl R, Engelhardt JF: Submucosal gland development in the airway is controlled by lymphoid enhancer binding factor 1 (LEF1). Development 1999, 126:4441-4453.
17. Mucenski ML, Wert SE, Nation JM, Loudy DE, Huelsken J, Birchmeier W, Morrisey EE, Whitsett JA: β-catenin is required for specification of proximal/distal cell fate during lung morphogenesis. J Biol Chem 2003, 278:40231-40238.
18. Galceran J, Hsu SC, Grosschedl R: Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression. Proc Natl Acad Sci USA 2001, 98:8668-8673.
19. DasGupta R, Fuchs E: Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 1999, 126:4557-4568.
20. Hsu SC, Galceran J, Grosschedl R: Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with β-catenin. Mol Cell Biol 1998, 18:4807-4818.
21. Wert SE, Glasser SW, Korfhagen TR, Whitsett JA: Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Dev Biol 1993, 156:426-443.
22. Additional data on Hogan lab website [http://web.cellbio.duke.edu/ ~bhogan/]
23. de Sauvage FJ, Keshav S, Kuang WJ, Gillett N, Henzel W, Goeddel DV: Precursor structure, expression, and tissue distribution of human guanylin. Proc Natl Acad Sci USA 1992, 89:9089-9093.
24. Stappenbeck TS, Mills JC, Gordon JI: Molecular features of adult mouse small intestinal epithelial progenitors. Proc Natl Acad Sci USA 2003, 100:1004-1009.
25. van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, van der Horn K, Batlle E, Coudreuse D, Haramis AP et al.: The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002, 111:241-250.
26. Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M, Kageyama R, Guillemot F, Serup P, Madsen OD: Control of endodermal endocrine development by Hes-1. Nat Genet 2000, 24:36-44.
27. Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ: The zinc finger transcription factor Gfil, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development 2003, 130:221-232.
28. Lickert H, Domon C, Huls G, Wehrle C, Duluc I, Clevers H, Meyer BI, Freund J, Kemler R: Wnt/β-catenin signaling regulates the expression of the homeobox gene cdx1 in embryonic intestine. Development 2000, 127:3805-3813.
29. Batlle E, Henderson JT, Beghtel H, van den Born MM, Sancho E, Huls G, Meeldijk J, Robertson J, van de Wetering M, Pawson T, Clevers H: β-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 2002, 111:251-263.
30. Engelhardt JF: Stem cell niches in the mouse airway. Am J Respir Cell Mol Biol 2001, 24:649-652.
31. Giangreco A, Reynolds SD, Stripp BR: Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am J Pathol 2002, 161:173-182.
32. Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR: In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am J Physiol Lung Cell Mol Physiol 2004, 286:L643-L649.
33. Weaver M, Dunn NR, Hogan BL: Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis. Development 2000, 127:2695-2704.
34. Lumpkin EA, Collisson T, Parab P, Omer-Abdalla A, Haeberle H, Chen P, Doetzlhofer A, White P, Groves A, Segil N, Johnson JE: Math 1-driven GFP expression in the developing nervous system of transgenic mice. Gene Expr Patterns 2003, 3:389-395.
35. Sekine S, Shibata T, Matsuno Y, Maeshima A, Ishii G, Sakamoto M, Hirohashi S: β-catenin mutations in pulmonary blastomas-association with morule formation. J Pathol 2003, 200:214-221.
36. Niemann C, Owens DM, Hulsken J, Birchmeier W, Watt FM: Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development 2002, 129:95-109.
37. Merrill BJ, Gat U, DasGupta R, Fuchs E: Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev 2001, 15:1688-1705.
38. Braun KM, Niemann C, Jensen UB, Sundberg JP, Silva-Vargas V, Watt FM: Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis. Development 2003, 130:5241-5255.
39. Miyoshi K, Shillingford JM, Le Provost F, Gounari F, Bronson R, von Boehmer H, Taketo MM, Cardiff RD, Hennighausen L, Khazaie K: Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. Proc Natl Acad Sci USA 2002, 99:219-224.
40. Bierie B, Nozawa M, Renou JP, Shillingford JM, Morgan F, Oka T, Taketo MM, Cardiff RD, Miyoshi K, Wagner KU et al: Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation. Oncogene 2003, 22:3875-3887.
41. Ayabe T, Satchell DP, Pesendorfer P, Tanabe H, Wilson CL, Hagen SJ, Ouellette AJ: Activation of Paneth cell α-defensins in mouse small intestine. J Biol Chem 2002, 277:5219-5228.
42. Affymetrix [http://www.affymetrix.com]
43. Affymetrix GeneChip® Mouse Expression Set 430 [http://www.affymetrix. com/products/arrays/specific/mouse430.affx]
44. Silicon Genetics [http://www.silicongenetics.com]
45. Harada, N, Tamai Y, Ishikawa T, Sauer B, Takaku K, Oshima M, Taketo MM: Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene. EMBO J, 1999, 18:5931-5942.