메뉴 건너뛰기




Volumn 5, Issue 3, 2010, Pages 182-194

Copper status Abnormalities and how to measure them in neurodegenerative disorders

Author keywords

Alzheimer's disease; Ceruloplasmin; Ceruloplasmin enzymatic activity; Copper; Copper serum analysis; Free copper; Neurodegenerative disorders

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; BIOLOGICAL MARKER; CERULOPLASMIN; COPPER; CURCUMIN; METAL CHELATE;

EID: 78649337090     PISSN: 15748898     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488910793362395     Document Type: Article
Times cited : (12)

References (148)
  • 1
    • 0025126555 scopus 로고
    • Role of free radicals and catalytic metal ions in human disease: An overview
    • Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: An overview. Methods Enzymol 1990; 186: 1-85
    • (1990) Methods Enzymol , vol.186 , pp. 1-85
    • Halliwell, B.1    Gutteridge, J.M.2
  • 2
    • 0021351203 scopus 로고
    • Oxygen toxicity, oxygen radicals, transition metals and disease
    • Halliwell B, Gutteridge JM. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 1984; 219(1): 1-14
    • (1984) Biochem J , vol.219 , Issue.1 , pp. 1-14
    • Halliwell, B.1    Gutteridge, J.M.2
  • 3
    • 0033617578 scopus 로고    scopus 로고
    • Undetectable intracellular free copper: The requirement of a copper chaperone for superoxide dismutase
    • Rae TD, Schmidt PJ, Pufahl RA, Culotta VC, O'Halloran TV. Undetectable intracellular free copper: The requirement of a copper chaperone for superoxide dismutase. Science 1999; 284(5415): 805-8
    • (1999) Science , vol.284 , Issue.5415 , pp. 805-808
    • Rae, T.D.1    Schmidt, P.J.2    Pufahl, R.A.3    Culotta, V.C.4    O'Halloran, T.V.5
  • 7
    • 0034035616 scopus 로고    scopus 로고
    • Metals and neuroscience
    • Bush AI. Metals and neuroscience. Curr Opin Chem Biol 2000; 4(2): 184-91
    • (2000) Curr Opin Chem Biol , vol.4 , Issue.2 , pp. 184-191
    • Bush, A.I.1
  • 8
    • 0032887626 scopus 로고    scopus 로고
    • The role of copper in neurodegenerative disease
    • Waggoner DJ, Bartnikas TB, Gitlin JD. The role of copper in neurodegenerative disease. Neurobiol Dis 1999; 6(4): 221-30
    • (1999) Neurobiol Dis , vol.6 , Issue.4 , pp. 221-230
    • Waggoner, D.J.1    Bartnikas, T.B.2    Gitlin, J.D.3
  • 9
    • 51749108879 scopus 로고    scopus 로고
    • Role of copper in human neurological disorders
    • Desai V, Kaler SG. Role of copper in human neurological disorders. Am J Clin Nutr 2008; 88(3): 855S-8S
    • (2008) Am J Clin Nutr , vol.88 , Issue.3
    • Desai, V.1    Kaler, S.G.2
  • 10
    • 39349112330 scopus 로고    scopus 로고
    • Mechanisms for copper acquisition, distribution and regulation
    • Kim BE, Nevitt T, Thiele DJ. Mechanisms for copper acquisition, distribution and regulation. Nat Chem Biol 2008; 4(3): 176-85
    • (2008) Nat Chem Biol , vol.4 , Issue.3 , pp. 176-185
    • Kim, B.E.1    Nevitt, T.2    Thiele, D.J.3
  • 11
    • 73949137867 scopus 로고    scopus 로고
    • Agents complexing copper as a therapeutic strategy for the treatment of Alzheimer's disease
    • Squitti R, Salustri C. Agents complexing copper as a therapeutic strategy for the treatment of Alzheimer's disease. Curr Alzheimer Res 2009; 6(6): 476-87
    • (2009) Curr Alzheimer Res , vol.6 , Issue.6 , pp. 476-487
    • Squitti, R.1    Salustri, C.2
  • 12
    • 57649158930 scopus 로고    scopus 로고
    • Copper transport to the brain by the blood brain barrier and blood-CSF barrier
    • Choi BS, Zheng W. Copper transport to the brain by the blood brain barrier and blood-CSF barrier. Brain Res 2009; 1248: 14-21
    • (2009) Brain Res , vol.1248 , pp. 14-21
    • Choi, B.S.1    Zheng, W.2
  • 13
    • 0029930329 scopus 로고    scopus 로고
    • Localization of Menkes gene expression in the mouse brain; its association with neurological manifestations in Menkes model mice
    • Iwase T, Nishimura M, Sugimura H, Igarashi H, Ozawa F, Shinmura K, et al. Localization of Menkes gene expression in the mouse brain; its association with neurological manifestations in Menkes model mice. Acta Neuropathol 1996; 91(5): 482-8
    • (1996) Acta Neuropathol , vol.91 , Issue.5 , pp. 482-488
    • Iwase, T.1    Nishimura, M.2    Sugimura, H.3    Igarashi, H.4    Ozawa, F.5    Shinmura, K.6
  • 14
    • 0031829282 scopus 로고    scopus 로고
    • Copper efflux from murine microvascular cells requires expression of the menkes disease Cu-ATPase
    • Qian Y, Tiffany-Castiglioni E, Welsh J, Harris ED. Copper efflux from murine microvascular cells requires expression of the menkes disease Cu-ATPase. J Nutr 1998; 128(8): 1276-82
    • (1998) J Nutr , vol.128 , Issue.8 , pp. 1276-1282
    • Qian, Y.1    Tiffany-Castiglioni, E.2    Welsh, J.3    Harris, E.D.4
  • 15
    • 33746727678 scopus 로고    scopus 로고
    • Developmental changes in the expression of ATP7A during a critical period in postnatal neurodevelopment
    • Niciu MJ, Ma XM, El Meskini R, Ronnett GV, Mains RE, Eipper BA. Developmental changes in the expression of ATP7A during a critical period in postnatal neurodevelopment. Neuroscience 2006; 139(3): 947-64
    • (2006) Neuroscience , vol.139 , Issue.3 , pp. 947-964
    • Niciu, M.J.1    Ma, X.M.2    El Meskini, R.3    Ronnett, G.V.4    Mains, R.E.5    Eipper, B.A.6
  • 17
    • 0042634362 scopus 로고    scopus 로고
    • Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity, and memory
    • Turner PR, O'Connor K, Tate WP, Abraham WC. Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity, and memory. Prog Neurobiol 2003; 70: 1-32
    • (2003) Prog Neurobiol , vol.70 , pp. 1-32
    • Turner, P.R.1    O'Connor, K.2    Tate, W.P.3    Abraham, W.C.4
  • 18
    • 10644280708 scopus 로고    scopus 로고
    • Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease
    • Treiber C, Simons A, Strauss M, Hafner M, Cappai R, Bayer TA. Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease. J Biol Chem 2004; 279: 51958-64
    • (2004) J Biol Chem , vol.279 , pp. 51958-51964
    • Treiber, C.1    Simons, A.2    Strauss, M.3    Hafner, M.4    Cappai, R.5    Bayer, T.A.6
  • 19
    • 0037931743 scopus 로고    scopus 로고
    • Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis
    • Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, et al. Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis. J Biol Chem 2003; 278: 17401-7
    • (2003) J Biol Chem , vol.278 , pp. 17401-17407
    • Barnham, K.J.1    McKinstry, W.J.2    Multhaup, G.3    Galatis, D.4    Morton, C.J.5    Curtain, C.C.6
  • 20
    • 0037160028 scopus 로고    scopus 로고
    • Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron
    • Maynard CJ, Cappai R, Volitakis I, Cherny RA, White AR, Kea B. Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron. J Biol Chem 2002; 277: 44670-6
    • (2002) J Biol Chem , vol.277 , pp. 44670-44676
    • Maynard, C.J.1    Cappai, R.2    Volitakis, I.3    Cherny, R.A.4    White, A.R.5    Kea, B.6
  • 21
    • 0032830357 scopus 로고    scopus 로고
    • Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice
    • White AR, Reyes R, Mercer JF, Camakaris J, Zheng H, Bush AI, et al. Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice. Brain Res 1999; 842: 439-44
    • (1999) Brain Res , vol.842 , pp. 439-444
    • White, A.R.1    Reyes, R.2    Mercer, J.F.3    Camakaris, J.4    Zheng, H.5    Bush, A.I.6
  • 22
    • 5444235015 scopus 로고    scopus 로고
    • Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts
    • Bellingham SA, Ciccotosto GD, Needham BE, Fodero LR, White AR, Masters CL, et al. Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts. J Neurochem 2004; 91(2): 423-8
    • (2004) J Neurochem , vol.91 , Issue.2 , pp. 423-428
    • Bellingham, S.A.1    Ciccotosto, G.D.2    Needham, B.E.3    Fodero, L.R.4    White, A.R.5    Masters, C.L.6
  • 24
    • 0036400025 scopus 로고    scopus 로고
    • Ceruloplasmin metabolism and function
    • Hellman NE, Gitlin JD. Ceruloplasmin metabolism and function. Annu Rev Nutr 2002; 22: 439-58
    • (2002) Annu Rev Nutr , vol.22 , pp. 439-458
    • Hellman, N.E.1    Gitlin, J.D.2
  • 25
    • 0035965212 scopus 로고    scopus 로고
    • Copper transport and metabolism are normal in aceruloplasminemic mice
    • Meyer LA, Durley AP, Prohaska JR, Harris ZL. Copper transport and metabolism are normal in aceruloplasminemic mice. J Biol Chem 2001; 276(39): 36857-61
    • (2001) J Biol Chem , vol.276 , Issue.39 , pp. 36857-36861
    • Meyer, L.A.1    Durley, A.P.2    Prohaska, J.R.3    Harris, Z.L.4
  • 26
    • 0037656489 scopus 로고    scopus 로고
    • Genetic defects in copper metabolism
    • Shim H, Harris ZL. Genetic defects in copper metabolism. J Nutr 2003;133(5 Suppl 1): 1527S-31S
    • (2003) J Nutr , vol.133 , Issue.5 SUPPL 1
    • Shim, H.1    Harris, Z.L.2
  • 27
    • 0014298868 scopus 로고
    • Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase. 3. Effects of deuterium and temperature on the enzymic oxidation of ferrous ion
    • Osaki S, Walaas O. Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase. 3. Effects of deuterium and temperature on the enzymic oxidation of ferrous ion. Arch Biochem Biophys 1968; 125(3): 918-23
    • (1968) Arch Biochem Biophys , vol.125 , Issue.3 , pp. 918-923
    • Osaki, S.1    Walaas, O.2
  • 28
    • 0014027719 scopus 로고
    • The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum
    • Osaki S, Johnson DA, Frieden E. The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum. J Biol Chem 1966; 241(12): 2746-51
    • (1966) J Biol Chem , vol.241 , Issue.12 , pp. 2746-2751
    • Osaki, S.1    Johnson, D.A.2    Frieden, E.3
  • 29
    • 0015217690 scopus 로고
    • The mobilization of iron from the perfused mammalian liver by a serum copper enzyme, ferroxidase I
    • Osaki S, Johnson DA, Frieden E. The mobilization of iron from the perfused mammalian liver by a serum copper enzyme, ferroxidase I. J Biol Chem 1971; 246(9): 3018-23
    • (1971) J Biol Chem , vol.246 , Issue.9 , pp. 3018-3023
    • Osaki, S.1    Johnson, D.A.2    Frieden, E.3
  • 30
    • 0033534589 scopus 로고    scopus 로고
    • Ceruloplasmin ferroxidase activity stimulates cellular iron uptake by a trivalent cation-specific transport mechanism
    • Attieh ZK, Mukhopadhyay CK, Seshadri V, Tripoulas NA, Fox PL. Ceruloplasmin ferroxidase activity stimulates cellular iron uptake by a trivalent cation-specific transport mechanism. J Biol Chem 1999; 274(2): 1116-23
    • (1999) J Biol Chem , vol.274 , Issue.2 , pp. 1116-1123
    • Attieh, Z.K.1    Mukhopadhyay, C.K.2    Seshadri, V.3    Tripoulas, N.A.4    Fox, P.L.5
  • 32
    • 0038711587 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
    • Jeong SY, David S. Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system. J Biol Chem 2003; 278(29): 27144-8
    • (2003) J Biol Chem , vol.278 , Issue.29 , pp. 27144-27148
    • Jeong, S.Y.1    David, S.2
  • 33
    • 0018342680 scopus 로고
    • Copper regulation of ceruloplasmin in copper-deficient rats
    • Linder MC, Houle PA, Isaacs E, Moor JR, Scott LE. Copper regulation of ceruloplasmin in copper-deficient rats. Enzyme 1979; 24(1): 23-35
    • (1979) Enzyme , vol.24 , Issue.1 , pp. 23-35
    • Linder, M.C.1    Houle, P.A.2    Isaacs, E.3    Moor, J.R.4    Scott, L.E.5
  • 34
    • 33745726690 scopus 로고    scopus 로고
    • Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis)
    • Gaggelli E, Kozlowski H, Valensin D, Valensin G. Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis). Chem Rev 2006; 106(6): 1995-2044
    • (2006) Chem Rev , vol.106 , Issue.6 , pp. 1995-2044
    • Gaggelli, E.1    Kozlowski, H.2    Valensin, D.3    Valensin, G.4
  • 35
    • 0032704101 scopus 로고    scopus 로고
    • Antioxidants, oxidative stress, and degenerative neurological disorders
    • Floyd RA. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc Soc Exp Biol Med 1999; 222(3): 236-45
    • (1999) Proc Soc Exp Biol Med , vol.222 , Issue.3 , pp. 236-245
    • Floyd, R.A.1
  • 36
    • 72049102879 scopus 로고    scopus 로고
    • Copper in the brain and Alzheimer's disease
    • Hung YH, Bush AI, Cherny RA. Copper in the brain and Alzheimer's disease. J Biol Inorg Chem 2010;15(1): 61-76
    • (2010) J Biol Inorg Chem , vol.15 , Issue.1 , pp. 61-76
    • Hung, Y.H.1    Bush, A.I.2    Cherny, R.A.3
  • 37
    • 0027968067 scopus 로고
    • Localization of copper to afferent terminals in rat locus ceruleus, in contrast to mitochondrial copper in cerebellum
    • Sato M, Ohtomo K, Daimon T, Sugiyama T, Iijima K. Localization of copper to afferent terminals in rat locus ceruleus, in contrast to mitochondrial copper in cerebellum. J Histochem Cytochem 1994; 42(12): 1585-91
    • (1994) J Histochem Cytochem , vol.42 , Issue.12 , pp. 1585-1591
    • Sato, M.1    Ohtomo, K.2    Daimon, T.3    Sugiyama, T.4    Iijima, K.5
  • 38
    • 44849102395 scopus 로고    scopus 로고
    • Metals in neurobiology: Probing their chemistry and biology with molecular imaging
    • Que EL, Domaille DW, Chang CJ. Metals in neurobiology: Probing their chemistry and biology with molecular imaging. Chem Rev 2008; 108(5): 1517-49
    • (2008) Chem Rev , vol.108 , Issue.5 , pp. 1517-1549
    • Que, E.L.1    Domaille, D.W.2    Chang, C.J.3
  • 39
    • 0030569306 scopus 로고    scopus 로고
    • Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders
    • Loeffler DA, LeWitt PA, Juneau PL, Sima AA, Nguyen HU, DeMaggio AJ, et al. Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders. Brain Res 1996; 738(2): 265-74
    • (1996) Brain Res , vol.738 , Issue.2 , pp. 265-274
    • Loeffler, D.A.1    Lewitt, P.A.2    Juneau, P.L.3    Sima, A.A.4    Nguyen, H.U.5    Demaggio, A.J.6
  • 40
    • 0018192041 scopus 로고
    • Evidence for uptake of nonceruloplasminic copper in the brain: Effect of ionic copper and amino acids
    • Chutkow JG. Evidence for uptake of nonceruloplasminic copper in the brain: Effect of ionic copper and amino acids. Proc Soc Exp Biol Med 1978; 158(1): 113-6
    • (1978) Proc Soc Exp Biol Med , vol.158 , Issue.1 , pp. 113-116
    • Chutkow, J.G.1
  • 41
    • 0034105324 scopus 로고    scopus 로고
    • CSF copper concentrations, blood-brain barrier function, and coeruloplasmin synthesis during the treatment of Wilson's disease
    • Stuerenburg HJ. CSF copper concentrations, blood-brain barrier function, and coeruloplasmin synthesis during the treatment of Wilson's disease. J Neural Transm 2000; 107(3): 321-9
    • (2000) J Neural Transm , vol.107 , Issue.3 , pp. 321-329
    • Stuerenburg, H.J.1
  • 44
    • 0031176731 scopus 로고    scopus 로고
    • Forty years of electrothermal atomic absorption spectrometry. Advances and problems in theory
    • L'vov BV. Forty years of electrothermal atomic absorption spectrometry. Advances and problems in theory. Spectrochim Acta B 1997; 52: 1239-45
    • (1997) Spectrochim Acta B , vol.52 , pp. 1239-1245
    • L'vov, B.V.1
  • 46
    • 34248203137 scopus 로고    scopus 로고
    • Fast ultrasound-assisted extraction of copper, iron, manganese and zinc from human hair samples prior to flow injection flame atomic absorption spectrometric detection
    • Yebra-Biurrun MC, Cespon-Romero RM. Fast ultrasound-assisted extraction of copper, iron, manganese and zinc from human hair samples prior to flow injection flame atomic absorption spectrometric detection. Anal Bioanal Chem 2007; 388(3): 711-6
    • (2007) Anal Bioanal Chem , vol.388 , Issue.3 , pp. 711-716
    • Yebra-Biurrun, M.C.1    Cespon-Romero, R.M.2
  • 48
    • 39449114490 scopus 로고    scopus 로고
    • Determination of trace copper in water samples by flame atomic absorption spectrometry after preconcentration on a phosphoric acid functionalized cotton chelator
    • Renmin GD, Zhong K, Feng M, Liu X. Determination of trace copper in water samples by flame atomic absorption spectrometry after preconcentration on a phosphoric acid functionalized cotton chelator. J Serbian Chem Soc 2008; 73(2): 249-58
    • (2008) J Serbian Chem Soc , vol.73 , Issue.2 , pp. 249-258
    • Renmin, G.D.1    Zhong, K.2    Feng, M.3    Liu, X.4
  • 49
    • 23044512215 scopus 로고    scopus 로고
    • Effect of nitric acid for equal stabilization and sensitivity of different selenium species in electrothermal atomic absorption spectrometry
    • Feyime SM, Ataman OY. Effect of nitric acid for equal stabilization and sensitivity of different selenium species in electrothermal atomic absorption spectrometry. Anal Chem Acta 2005; 547: 126-31
    • (2005) Anal Chem Acta , vol.547 , pp. 126-131
    • Feyime, S.M.1    Ataman, O.Y.2
  • 53
    • 0024558099 scopus 로고
    • Sensitive, direct colorimetric assay for copper in serum
    • Abe A, Yamashita S, Noma A. Sensitive, direct colorimetric assay for copper in serum. Clin Chem 1989; 35(4): 552-4
    • (1989) Clin Chem , vol.35 , Issue.4 , pp. 552-554
    • Abe, A.1    Yamashita, S.2    Noma, A.3
  • 55
    • 67650813167 scopus 로고    scopus 로고
    • Evaluation of the Randox colorimetric serum copper and zinc assays against atomic absorption spectroscopy
    • Beckett JM, Hartley TF, Ball MJ. Evaluation of the Randox colorimetric serum copper and zinc assays against atomic absorption spectroscopy. Ann Clin Biochem 2009; 46(Pt 4): 322-6
    • (2009) Ann Clin Biochem , vol.46 , Issue.PART 4 , pp. 322-326
    • Beckett, J.M.1    Hartley, T.F.2    Ball, M.J.3
  • 56
    • 0028945240 scopus 로고
    • A quantitative test for copper using bicinchoninic acid
    • Brenner AJ, Harris ED. A quantitative test for copper using bicinchoninic acid. Anal Biochem 1995; 226(1): 80-4
    • (1995) Anal Biochem , vol.226 , Issue.1 , pp. 80-84
    • Brenner, A.J.1    Harris, E.D.2
  • 57
    • 77951256830 scopus 로고    scopus 로고
    • Standardization of ceruloplasmin measurements is still an issue despite the availability of a common reference material
    • Infusino I, Valente C, Dolci A, Panteghini M. Standardization of ceruloplasmin measurements is still an issue despite the availability of a common reference material. Anal Bioanal Chem 2010; 397(2): 521-5
    • (2010) Anal Bioanal Chem , vol.397 , Issue.2 , pp. 521-525
    • Infusino, I.1    Valente, C.2    Dolci, A.3    Panteghini, M.4
  • 60
    • 0037350153 scopus 로고    scopus 로고
    • Wilson's disease: The importance of measuring serum caeruloplasmin non-immunologically
    • Walshe JM. Wilson's disease: The importance of measuring serum caeruloplasmin non-immunologically. Ann Clin Biochem 2003; 40(Pt 2): 115-21
    • (2003) Ann Clin Biochem , vol.40 , Issue.PART 2 , pp. 115-121
    • Walshe, J.M.1
  • 63
    • 0009710564 scopus 로고
    • Metalloenzymes and myocardial infarction. I. The relation between serum copper and ceruloplasmin and its catalytic activity
    • Adelstein SJ, Coombs TL, Vallee BL. Metalloenzymes and myocardial infarction. I. The relation between serum copper and ceruloplasmin and its catalytic activity. N Engl J Med 1956; 255(3): 105-9
    • (1956) N Engl J Med , vol.255 , Issue.3 , pp. 105-109
    • Adelstein, S.J.1    Coombs, T.L.2    Vallee, B.L.3
  • 64
    • 0014883924 scopus 로고
    • Measurement of human serum ceruloplasmin by its p-phenylenediamine oxidase activity
    • Sunderman FW, Jr., Nomoto S. Measurement of human serum ceruloplasmin by its p-phenylenediamine oxidase activity. Clin Chem 1970; 16(11): 903-10
    • (1970) Clin Chem , vol.16 , Issue.11 , pp. 903-910
    • Sunderman Jr., F.W.1    Nomoto, S.2
  • 65
    • 0025058904 scopus 로고
    • A kinetic method for determination of serum ceruloplasmin
    • Mukerjee H. A kinetic method for determination of serum ceruloplasmin. Clin Chem 1990; 36(2): 391-2
    • (1990) Clin Chem , vol.36 , Issue.2 , pp. 391-392
    • Mukerjee, H.1
  • 66
    • 0016331976 scopus 로고
    • Measurement of ceruloplasmin from its oxidase activity in serum by use of odianisidine dihydrochloride
    • Schosinsky KH, Lehmann HP, Beeler MF. Measurement of ceruloplasmin from its oxidase activity in serum by use of odianisidine dihydrochloride. Clin Chem 1974; 20(12): 1556-63
    • (1974) Clin Chem , vol.20 , Issue.12 , pp. 1556-1563
    • Schosinsky, K.H.1    Lehmann, H.P.2    Beeler, M.F.3
  • 67
    • 0016311191 scopus 로고
    • Standardization of serum ceruloplasmin concentrations in international enzyme units with o-Dianisidine dihydrochloride as substrate
    • Lehmann HP, Schosinsky KH, Beeler MF. Standardization of serum ceruloplasmin concentrations in international enzyme units with o-Dianisidine dihydrochloride as substrate. Clin Chem 1974; 20(12): 1564-7
    • (1974) Clin Chem , vol.20 , Issue.12 , pp. 1564-1567
    • Lehmann, H.P.1    Schosinsky, K.H.2    Beeler, M.F.3
  • 68
    • 0023914572 scopus 로고
    • An automated method for the kinetic measurement of ferroxidase activity
    • Winkles J, Jones AF, Winyard P, Blake DR, Lunec J. An automated method for the kinetic measurement of ferroxidase activity. Ann Clin Biochem 1988; 25 (Pt 3): 250-4
    • (1988) Ann Clin Biochem , vol.25 , Issue.PART 3 , pp. 250-254
    • Winkles, J.1    Jones, A.F.2    Winyard, P.3    Blake, D.R.4    Lunec, J.5
  • 69
    • 0031760199 scopus 로고    scopus 로고
    • Automated measurement of serum ferroxidase activity
    • Erel O. Automated measurement of serum ferroxidase activity. Clin Chem 1998; 44(11): 2313-9
    • (1998) Clin Chem , vol.44 , Issue.11 , pp. 2313-2319
    • Erel, O.1
  • 70
    • 65649083034 scopus 로고    scopus 로고
    • Usefulness of ferroxidase activity of ceruloplasmin in the diagnosis of Wilson's Disease
    • Fleming JJ, Santhosh S, Selvakumar R, Jose A, Eapen E. Usefulness of ferroxidase activity of ceruloplasmin in the diagnosis of Wilson's Disease. Indian J Clin Biochem 2009; 24(1): 15-22
    • (2009) Indian J Clin Biochem , vol.24 , Issue.1 , pp. 15-22
    • Fleming, J.J.1    Santhosh, S.2    Selvakumar, R.3    Jose, A.4    Eapen, E.5
  • 71
    • 34247121506 scopus 로고    scopus 로고
    • A kinetic method amenable to automation for ceruloplasmin estimation with inexpensive and stable reagents
    • Somani BL, Ambade V. A kinetic method amenable to automation for ceruloplasmin estimation with inexpensive and stable reagents. Clin Biochem 2007; 40(8): 571-4
    • (2007) Clin Biochem , vol.40 , Issue.8 , pp. 571-574
    • Somani, B.L.1    Ambade, V.2
  • 72
    • 33747065282 scopus 로고    scopus 로고
    • Adjusting copper concentrations for caeruloplasmin levels in routine clinical practice
    • Twomey PJ, Viljoen A, House IM, Reynolds TM, Wierzbicki AS. Adjusting copper concentrations for caeruloplasmin levels in routine clinical practice. J Clin Pathol 2006; 59(8): 867-9
    • (2006) J Clin Pathol , vol.59 , Issue.8 , pp. 867-869
    • Twomey, P.J.1    Viljoen, A.2    House, I.M.3    Reynolds, T.M.4    Wierzbicki, A.S.5
  • 74
    • 2942579169 scopus 로고    scopus 로고
    • Comparison of ultrafiltration and solid phase extraction for the separation of free and protein-bound serum copper for the Wilson's disease diagnosis
    • Bohrer D, Do Nascimento PC, Ramirez AG, Mendonca JK, De Carvalho LM, Pomblum SC. Comparison of ultrafiltration and solid phase extraction for the separation of free and protein-bound serum copper for the Wilson's disease diagnosis. Clin Chim Acta 2004; 345(1-2): 113-21
    • (2004) Clin Chim Acta , vol.345 , Issue.1-2 , pp. 113-121
    • Bohrer, D.1    Do Nascimento, P.C.2    Ramirez, A.G.3    Mendonca, J.K.4    de Carvalho, L.M.5    Pomblum, S.C.6
  • 75
    • 58849122810 scopus 로고    scopus 로고
    • Direct measurement of free copper in serum or plasma ultrafiltrate
    • McMillin GA, Travis JJ, Hunt JW. Direct measurement of free copper in serum or plasma ultrafiltrate. Am J Clin Pathol 2009; 131(2): 160-5
    • (2009) Am J Clin Pathol , vol.131 , Issue.2 , pp. 160-165
    • McMillin, G.A.1    Travis, J.J.2    Hunt, J.W.3
  • 76
    • 48449094910 scopus 로고    scopus 로고
    • Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NO(x) content in the CSF. A different marker profile in four neurodegenerative diseases
    • Boll MC, Alcaraz-Zubeldia M, Montes S, Rios C. Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NO(x) content in the CSF. A different marker profile in four neurodegenerative diseases. Neurochem Res 2008; 33(9): 1717-23
    • (2008) Neurochem Res , vol.33 , Issue.9 , pp. 1717-1723
    • Boll, M.C.1    Alcaraz-Zubeldia, M.2    Montes, S.3    Rios, C.4
  • 80
    • 0036820980 scopus 로고    scopus 로고
    • Copper transporting P-type ATPases and human disease
    • Cox DW, Moore SD. Copper transporting P-type ATPases and human disease. J Bioenerg Biomembr 2002; 34(5): 333-8
    • (2002) J Bioenerg Biomembr , vol.34 , Issue.5 , pp. 333-338
    • Cox, D.W.1    Moore, S.D.2
  • 81
    • 0031598230 scopus 로고    scopus 로고
    • Metabolic and molecular bases of Menkes disease and occipital horn syndrome
    • Kaler SG. Metabolic and molecular bases of Menkes disease and occipital horn syndrome. Pediatr Dev Pathol 1998; 1(1): 85-98
    • (1998) Pediatr Dev Pathol , vol.1 , Issue.1 , pp. 85-98
    • Kaler, S.G.1
  • 82
    • 0027431996 scopus 로고
    • Isolation and characterization of a human liver cDNA as a candidate gene for Wilson disease
    • Yamaguchi Y, Heiny ME, Gitlin JD. Isolation and characterization of a human liver cDNA as a candidate gene for Wilson disease. Biochem Biophys Res Commun 1993; 197(1): 271-7
    • (1993) Biochem Biophys Res Commun , vol.197 , Issue.1 , pp. 271-277
    • Yamaguchi, Y.1    Heiny, M.E.2    Gitlin, J.D.3
  • 83
    • 0027452091 scopus 로고
    • The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene
    • Bull PC, Thomas GR, Rommens JM, Forbes JR, Cox DW. The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene. Nat Genet 1993; 5(4): 327-37
    • (1993) Nat Genet , vol.5 , Issue.4 , pp. 327-337
    • Bull, P.C.1    Thomas, G.R.2    Rommens, J.M.3    Forbes, J.R.4    Cox, D.W.5
  • 84
    • 0027364961 scopus 로고
    • The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene
    • Tanzi RE, Petrukhin K, Chernov I, Pellequer JL, Wasco W, Ross B, et al. The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene. Nat Genet 1993; 5(4): 344-50
    • (1993) Nat Genet , vol.5 , Issue.4 , pp. 344-350
    • Tanzi, R.E.1    Petrukhin, K.2    Chernov, I.3    Pellequer, J.L.4    Wasco, W.5    Ross, B.6
  • 86
    • 77649312565 scopus 로고    scopus 로고
    • Truncating mutations in the Wilson disease gene ATP7B are associated with very low serum ceruloplasmin oxidase activity and an early onset of Wilson disease
    • Merle U, Weiss KH, Eisenbach C, Tuma S, Ferenci P, Stremmel W. Truncating mutations in the Wilson disease gene ATP7B are associated with very low serum ceruloplasmin oxidase activity and an early onset of Wilson disease. BMC Gastroenterol 2010; 10: 8
    • (2010) BMC Gastroenterol , vol.10 , pp. 8
    • Merle, U.1    Weiss, K.H.2    Eisenbach, C.3    Tuma, S.4    Ferenci, P.5    Stremmel, W.6
  • 87
    • 70349748259 scopus 로고    scopus 로고
    • Serum ceruloplasmin oxidase activity is a sensitive and highly specific diagnostic marker for Wilson's disease
    • Merle U, Eisenbach C, Weiss KH, Tuma S, Stremmel W. Serum ceruloplasmin oxidase activity is a sensitive and highly specific diagnostic marker for Wilson's disease. J Hepatol 2009; 51(5): 925-30
    • (2009) J Hepatol , vol.51 , Issue.5 , pp. 925-930
    • Merle, U.1    Eisenbach, C.2    Weiss, K.H.3    Tuma, S.4    Stremmel, W.5
  • 88
    • 0027385359 scopus 로고
    • Wilson's disease with cerebral manifestation: Monitoring therapy by CSF copper concentration
    • Hartard C, Weisner B, Dieu C, Kunze K. Wilson's disease with cerebral manifestation: Monitoring therapy by CSF copper concentration. J Neurol 1993; 241(2): 101-7
    • (1993) J Neurol , vol.241 , Issue.2 , pp. 101-107
    • Hartard, C.1    Weisner, B.2    Dieu, C.3    Kunze, K.4
  • 89
    • 44549087765 scopus 로고    scopus 로고
    • Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior
    • Selkoe DJ. Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior. Behav Brain Res 2008; 192(1): 106-13
    • (2008) Behav Brain Res , vol.192 , Issue.1 , pp. 106-113
    • Selkoe, D.J.1
  • 90
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy JA, Higgins GA. Alzheimer's disease: The amyloid cascade hypothesis. Science 1992; 256(5054): 184-5
    • (1992) Science , vol.256 , Issue.5054 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 91
    • 34447634140 scopus 로고    scopus 로고
    • The modulation of metal bio availability as a therapeutic strategy for the treatment of Alzheimer's disease
    • Crouch PJ, White AR, Bush AI. The modulation of metal bio availability as a therapeutic strategy for the treatment of Alzheimer's disease. FEBS J 2007; 274(15): 3775-83
    • (2007) FEBS J , vol.274 , Issue.15 , pp. 3775-3783
    • Crouch, P.J.1    White, A.R.2    Bush, A.I.3
  • 93
    • 33645407628 scopus 로고    scopus 로고
    • Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS
    • Ma Q, Li Y, Du J, Liu H, Kanazawa K, Nemoto T, et al. Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS. Peptides 2006; 27(4): 841-9
    • (2006) Peptides , vol.27 , Issue.4 , pp. 841-849
    • Ma, Q.1    Li, Y.2    Du, J.3    Liu, H.4    Kanazawa, K.5    Nemoto, T.6
  • 94
    • 0037174856 scopus 로고    scopus 로고
    • Metalloenzyme-like activity of Alzheimer's disease beta amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2)
    • Opazo C, Huang X, Cherny RA, Moir RD, Roher AE, White AR, et al. Metalloenzyme-like activity of Alzheimer's disease beta amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). J Biol Chem 2002; 277(43): 40302-8
    • (2002) J Biol Chem , vol.277 , Issue.43 , pp. 40302-40308
    • Opazo, C.1    Huang, X.2    Cherny, R.A.3    Moir, R.D.4    Roher, A.E.5    White, A.R.6
  • 95
    • 0033528666 scopus 로고    scopus 로고
    • Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations
    • Moir RD, Atwood CS, Romano DM, Laurans MH, Huang X, Bush AI, et al. Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations. Biochemistry 1999; 38(14): 4595-603
    • (1999) Biochemistry , vol.38 , Issue.14 , pp. 4595-4603
    • Moir, R.D.1    Atwood, C.S.2    Romano, D.M.3    Laurans, M.H.4    Huang, X.5    Bush, A.I.6
  • 96
    • 0028026587 scopus 로고
    • Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3
    • Sanan DA, Weisgraber KH, Russell SJ, Mahley RW, Huang D, Saunders A, et al. Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. J Clin Invest 1994; 94(2): 860-9
    • (1994) J Clin Invest , vol.94 , Issue.2 , pp. 860-869
    • Sanan, D.A.1    Weisgraber, K.H.2    Russell, S.J.3    Mahley, R.W.4    Huang, D.5    Saunders, A.6
  • 97
    • 0030885482 scopus 로고    scopus 로고
    • Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
    • Smith MA, Harris PL, Sayre LM, Perry G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci USA 1997; 94(18): 9866-8
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.18 , pp. 9866-9868
    • Smith, M.A.1    Harris, P.L.2    Sayre, L.M.3    Perry, G.4
  • 98
    • 46749100924 scopus 로고    scopus 로고
    • Therapeutics for Alzheimer's disease based on the metal hypothesis
    • Bush AI, Tanzi RE. Therapeutics for Alzheimer's disease based on the metal hypothesis. Neurotherapeutics 2008; 5(3): 421-32
    • (2008) Neurotherapeutics , vol.5 , Issue.3 , pp. 421-432
    • Bush, A.I.1    Tanzi, R.E.2
  • 99
    • 2442586535 scopus 로고    scopus 로고
    • Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene
    • Bellingham SA, Lahiri DK, Maloney B, La Fontaine S, Multhaup G, Camakaris J. Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene. J Biol Chem 2004; 279(19): 20378-86
    • (2004) J Biol Chem , vol.279 , Issue.19 , pp. 20378-20386
    • Bellingham, S.A.1    Lahiri, D.K.2    Maloney, B.3    la Fontaine, S.4    Multhaup, G.5    Camakaris, J.6
  • 100
    • 15244341973 scopus 로고    scopus 로고
    • Gene expression profiling in chronic copper overload reveals upregulation of Prnp and App
    • Armendariz AD, Gonzalez M, Loguinov AV, Vulpe CD. Gene expression profiling in chronic copper overload reveals upregulation of Prnp and App. Physiol Genomics 2004; 20(1): 45-54
    • (2004) Physiol Genomics , vol.20 , Issue.1 , pp. 45-54
    • Armendariz, A.D.1    Gonzalez, M.2    Loguinov, A.V.3    Vulpe, C.D.4
  • 101
    • 45849148467 scopus 로고    scopus 로고
    • Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: Blockage By Curcumin
    • Lin R, Chen X, Li W, Han Y, Liu P, Pi R. Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: Blockage by curcumin. Neurosci Lett 2008; 440(3): 344-7
    • (2008) Neurosci Lett , vol.440 , Issue.3 , pp. 344-347
    • Lin, R.1    Chen, X.2    Li, W.3    Han, Y.4    Liu, P.5    Pi, R.6
  • 102
    • 15744368246 scopus 로고    scopus 로고
    • Intermed Medical Publisher: Amsterdam
    • Hoogenraad T. Wilson's Disease. Intermed Medical Publisher: Amsterdam 2001
    • (2001) Wilson's Disease
    • Hoogenraad, T.1
  • 103
    • 36749090530 scopus 로고    scopus 로고
    • 'Free' copper in serum of Alzheimer's disease patients correlates with markers of liver function
    • Squitti R, Ventriglia M, Barbati G, Cassetta E, Ferreri F, Dal Forno G, et al. 'Free' copper in serum of Alzheimer's disease patients correlates with markers of liver function. J Neural Transm 2007; 114(12): 1589-94
    • (2007) J Neural Transm , vol.114 , Issue.12 , pp. 1589-1594
    • Squitti, R.1    Ventriglia, M.2    Barbati, G.3    Cassetta, E.4    Ferreri, F.5    Dal Forno, G.6
  • 104
    • 20144371701 scopus 로고    scopus 로고
    • Excess of serum copper not related to ceruloplasmin in Alzheimer disease
    • Squitti R, Pasqualetti P, Dal Forno G, Moffa F, Cassetta E, Lupoi D, et al. Excess of serum copper not related to ceruloplasmin in Alzheimer disease. Neurology 2005; 64(6): 1040-6
    • (2005) Neurology , vol.64 , Issue.6 , pp. 1040-1046
    • Squitti, R.1    Pasqualetti, P.2    Dal Forno, G.3    Moffa, F.4    Cassetta, E.5    Lupoi, D.6
  • 105
    • 77049115153 scopus 로고
    • Clinical utility of copper, ceruloplasmin, and metallothionein plasma determinations in human neurodegenerative patients and their first-degree relatives
    • Arnal N, Cristalli DO, de Alaniz MJ, Marra CA. Clinical utility of copper, ceruloplasmin, and metallothionein plasma determinations in human neurodegenerative patients and their first-degree relatives. Brain Res 2010; 1319: 118-30
    • (1319) Brain Res , vol.2010 , pp. 118-130
    • Arnal, N.1    Cristalli, D.O.2    de Alaniz, M.J.3    Marra, C.A.4
  • 108
    • 0036174035 scopus 로고    scopus 로고
    • Malondialdehyde, superoxide dismutase, melatonin, iron, copper, and zinc blood concentrations in patients with Alzheimer disease: Cross-sectional study
    • Ozcankaya R, Delibas N. Malondialdehyde, superoxide dismutase, melatonin, iron, copper, and zinc blood concentrations in patients with Alzheimer disease: cross-sectional study. Croat Med J 2002; 43(1): 28-32
    • (2002) Croat Med J , vol.43 , Issue.1 , pp. 28-32
    • Ozcankaya, R.1    Delibas, N.2
  • 109
    • 70449512334 scopus 로고    scopus 로고
    • Study of serum copper and ceruloplasmin in Alzheimer's disease in Kerman, Iran
    • Sedighi B, Shafa MA, Shariati M. A study of serum copper and ceruloplasmin in Alzheimer's disease in Kerman, Iran. Neurology Asia 2006; 11: 107-9
    • (2006) Neurology Asia , vol.11 , pp. 107-109
    • Sedighi, B.1    Shafa, M.A.2    Shariati, M.A.3
  • 110
    • 31644448061 scopus 로고    scopus 로고
    • Monitoring of chemical elements and oxidative damage in patients affected by Alzheimer's disease
    • Bocca B, Forte G, Petrucci F, Pino A, Marchione F, Bomboi G, et al. Monitoring of chemical elements and oxidative damage in patients affected by Alzheimer's disease. Ann Ist Super Sanita 2005; 41(2): 197-203
    • (2005) Ann Ist Super Sanita , vol.41 , Issue.2 , pp. 197-203
    • Bocca, B.1    Forte, G.2    Petrucci, F.3    Pino, A.4    Marchione, F.5    Bomboi, G.6
  • 111
    • 0033062186 scopus 로고    scopus 로고
    • Serum zinc, copper, insulin and lipids in Alzheimer's disease epsilon 4 apolipoprotein: E Allele Carriers
    • Gonzalez C, Martin T, Cacho J, Brenas MT, Arroyo T, Garcia-Berrocal B, et al. Serum zinc, copper, insulin and lipids in Alzheimer's disease epsilon 4 apolipoprotein E allele carriers. Eur J Clin Invest 1999; 29(7): 637-42
    • (1999) Eur J Clin Invest , vol.29 , Issue.7 , pp. 637-642
    • Gonzalez, C.1    Martin, T.2    Cacho, J.3    Brenas, M.T.4    Arroyo, T.5    Garcia-Berrocal, B.6
  • 113
    • 78649367666 scopus 로고    scopus 로고
    • Can serum levels of copper and zinc distinguish Alzheimer's patients from normal subjects?
    • Sevim S, Ünal O, Tamer L, Do u O, Özge A. Can serum levels of copper and zinc distinguish Alzheimer's patients from normal subjects? J Neurol Sci 2007; 24(3): 197-205
    • (2007) J Neurol Sci , vol.24 , Issue.3 , pp. 197-205
    • Sevim, S.1    Ünal, O.2    Tamer, L.3    Do u, O.4    Özge, A.5
  • 115
    • 33746792029 scopus 로고    scopus 로고
    • Excess of nonceruloplasmin serum copper in AD correlates with MMSE, CSF [beta]-amyloid, and h-tau
    • Squitti R, Barbati G, Rossi L, Ventriglia M, Dal Forno G, Cesaretti S, et al. Excess of nonceruloplasmin serum copper in AD correlates with MMSE, CSF [beta]-amyloid, and h-tau. Neurology 2006; 67(1): 76-82
    • (2006) Neurology , vol.67 , Issue.1 , pp. 76-82
    • Squitti, R.1    Barbati, G.2    Rossi, L.3    Ventriglia, M.4    Dal Forno, G.5    Cesaretti, S.6
  • 116
    • 33745860362 scopus 로고    scopus 로고
    • Degradation of the Alzheimer disease amyloid beta peptide by metal-dependent up-regulation of metalloprotease activity
    • White AR, Du T, Laughton KM, Volitakis I, Sharples RA, Xilinas ME, et al. Degradation of the Alzheimer disease amyloid beta peptide by metal-dependent up-regulation of metalloprotease activity. J Biol Chem 2006; 281(26): 17670-80
    • (2006) J Biol Chem , vol.281 , Issue.26 , pp. 17670-17680
    • White, A.R.1    Du, T.2    Laughton, K.M.3    Volitakis, I.4    Sharples, R.A.5    Xilinas, M.E.6
  • 117
    • 42549102390 scopus 로고    scopus 로고
    • Features of ceruloplasmin in the cerebrospinal fluid of Alzheimer's disease patients
    • Capo CR, Arciello M, Squitti R, Cassetta E, Rossini PM, Calabrese L, et al. Features of ceruloplasmin in the cerebrospinal fluid of Alzheimer's disease patients. Biometals 2008; 21(3): 367-72
    • (2008) Biometals , vol.21 , Issue.3 , pp. 367-372
    • Capo, C.R.1    Arciello, M.2    Squitti, R.3    Cassetta, E.4    Rossini, P.M.5    Calabrese, L.6
  • 118
    • 15444373250 scopus 로고    scopus 로고
    • Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease
    • Rasia RM, Bertoncini CW, Marsh D, Hoyer W, Cherny D, Zweckstetter M, et al. Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease. Proc Natl Acad Sci USA 2005; 102(12): 4294-9
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.12 , pp. 4294-4299
    • Rasia, R.M.1    Bertoncini, C.W.2    Marsh, D.3    Hoyer, W.4    Cherny, D.5    Zweckstetter, M.6
  • 119
    • 0026704075 scopus 로고
    • Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group
    • Dexter DT, Jenner P, Schapira AH, Marsden CD. Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group. Ann Neurol 1992; 32 Suppl: S94-100
    • (1992) Ann Neurol , vol.32 , Issue.SUPPL.
    • Dexter, D.T.1    Jenner, P.2    Schapira, A.H.3    Marsden, C.D.4
  • 120
    • 27744446323 scopus 로고    scopus 로고
    • Functional relevance of ceruloplasmin mutations in Parkinson's disease
    • Hochstrasser H, Tomiuk J, Walter U, Behnke S, Spiegel J, Kruger R, et al. Functional relevance of ceruloplasmin mutations in Parkinson's disease. FASEB J 2005; 19(13): 1851-3
    • (2005) FASEB J , vol.19 , Issue.13 , pp. 1851-1853
    • Hochstrasser, H.1    Tomiuk, J.2    Walter, U.3    Behnke, S.4    Spiegel, J.5    Kruger, R.6
  • 121
    • 0023237555 scopus 로고
    • Raised cerebrospinal-fluid copper concentration in Parkinson's disease
    • Pall HS, Williams AC, Blake DR, Lunec J, Gutteridge JM, Hall M, et al. Raised cerebrospinal-fluid copper concentration in Parkinson's disease. Lancet 1987; 2(8553): 238-41
    • (1987) Lancet , vol.2 , Issue.8553 , pp. 238-241
    • Pall, H.S.1    Williams, A.C.2    Blake, D.R.3    Lunec, J.4    Gutteridge, J.M.5    Hall, M.6
  • 122
    • 0031981976 scopus 로고    scopus 로고
    • Aceruloplasminemia: An inherited neurodegenerative disease with impairment of iron homeostasis
    • Harris ZL, Klomp LW, Gitlin JD. Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis. Am J Clin Nutr 1998;67(5 Suppl): 972S-7S
    • (1998) Am J Clin Nutr , vol.67 , Issue.SUPPL
    • Harris, Z.L.1    Klomp, L.W.2    Gitlin, J.D.3
  • 123
    • 0029007765 scopus 로고
    • Hereditary ceruloplasmin deficiency with hemosiderosis: A clinicopathological study of a Japanese family
    • Morita H, Ikeda S, Yamamoto K, Morita S, Yoshida K, Nomoto S, et al. Hereditary ceruloplasmin deficiency with hemosiderosis: A clinicopathological study of a Japanese family. Ann Neurol 1995; 37(5): 646-56
    • (1995) Ann Neurol , vol.37 , Issue.5 , pp. 646-656
    • Morita, H.1    Ikeda, S.2    Yamamoto, K.3    Morita, S.4    Yoshida, K.5    Nomoto, S.6
  • 125
    • 34547782810 scopus 로고    scopus 로고
    • Copper and iron disorders of the brain
    • Madsen E, Gitlin JD. Copper and iron disorders of the brain. Annu Rev Neurosci 2007; 30: 317-37
    • (2007) Annu Rev Neurosci , vol.30 , pp. 317-337
    • Madsen, E.1    Gitlin, J.D.2
  • 127
    • 0027164824 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen DR. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993; 364(6435): 362
    • (1993) Nature , vol.364 , Issue.6435 , pp. 362
    • Rosen, D.R.1
  • 128
    • 0027426169 scopus 로고
    • Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase
    • Deng HX, Hentati A, Tainer JA, Iqbal Z, Cayabyab A, Hung WY, et al. Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 1993; 261(5124): 1047-51
    • (1993) Science , vol.261 , Issue.5124 , pp. 1047-1051
    • Deng, H.X.1    Hentati, A.2    Tainer, J.A.3    Iqbal, Z.4    Cayabyab, A.5    Hung, W.Y.6
  • 129
    • 34247125547 scopus 로고    scopus 로고
    • Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis
    • Watanabe S, Nagano S, Duce J, Kiaei M, Li QX, Tucker SM, et al. Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis. Free Radic Biol Med 2007; 42(10): 1534-42
    • (2007) Free Radic Biol Med , vol.42 , Issue.10 , pp. 1534-1542
    • Watanabe, S.1    Nagano, S.2    Duce, J.3    Kiaei, M.4    Li, Q.X.5    Tucker, S.M.6
  • 130
    • 66749175710 scopus 로고    scopus 로고
    • A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis
    • Trumbull KA, Beckman JS. A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis. Antioxid Redox Signal 2009; 11(7): 1627-39
    • (2009) Antioxid Redox Signal , vol.11 , Issue.7 , pp. 1627-1639
    • Trumbull, K.A.1    Beckman, J.S.2
  • 132
    • 63849241137 scopus 로고    scopus 로고
    • Longitudinal prognostic value of serum free copper in patients with Alzheimer disease
    • Squitti R, Bressi F, Pasqualetti P, Bonomini C, Ghidoni R, Binetti G, et al. Longitudinal prognostic value of serum free copper in patients with Alzheimer disease. Neurology 2009; 72(1): 50-5
    • (2009) Neurology , vol.72 , Issue.1 , pp. 50-55
    • Squitti, R.1    Bressi, F.2    Pasqualetti, P.3    Bonomini, C.4    Ghidoni, R.5    Binetti, G.6
  • 133
    • 48949098573 scopus 로고    scopus 로고
    • Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: A phase IIa, double-blind, randomised, placebo-controlled trial
    • Lannfelt L, Blennow K, Zetterberg H, Batsman S, Ames D, Harrison J, et al. Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: A phase IIa, double-blind, randomised, placebo-controlled trial. Lancet Neurol 2008; 7(9): 779-86
    • (2008) Lancet Neurol , vol.7 , Issue.9 , pp. 779-786
    • Lannfelt, L.1    Blennow, K.2    Zetterberg, H.3    Batsman, S.4    Ames, D.5    Harrison, J.6
  • 134
    • 46149107512 scopus 로고    scopus 로고
    • Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta
    • Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, et al. Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta. Neuron 2008; 59(1): 43-55
    • (2008) Neuron , vol.59 , Issue.1 , pp. 43-55
    • Adlard, P.A.1    Cherny, R.A.2    Finkelstein, D.I.3    Gautier, E.4    Robb, E.5    Cortes, M.6
  • 135
    • 77953427267 scopus 로고    scopus 로고
    • Is it time for biomarker-based diagnostic criteria for prodromal Alzheimer's disease?
    • Blennow K, Zetterberg H. Is it time for biomarker-based diagnostic criteria for prodromal Alzheimer's disease? Alzheimers Res Ther 2010; 2(2): 8
    • (2010) Alzheimers Res Ther , vol.2 , Issue.2 , pp. 8
    • Blennow, K.1    Zetterberg, H.2
  • 138
    • 77649182895 scopus 로고    scopus 로고
    • Is cognitive function linked to serum free copper levels? A cohort study in a normal population
    • Salustri C, Barbati G, Ghidoni R, Quintiliani L, Ciappina S, Binetti G, et al. Is cognitive function linked to serum free copper levels? A cohort study in a normal population. Clin Neurophysiol 2010; 121(4): 502-7
    • (2010) Clin Neurophysiol , vol.121 , Issue.4 , pp. 502-507
    • Salustri, C.1    Barbati, G.2    Ghidoni, R.3    Quintiliani, L.4    Ciappina, S.5    Binetti, G.6
  • 139
    • 34248352230 scopus 로고    scopus 로고
    • Free copper and resting temporal EEG rhythms correlate across healthy, mild cognitive impairment, and Alzheimer's disease subjects
    • Babiloni C, Squitti R, Del Percio C, Cassetta E, Ventriglia MC, Ferreri F, et al. Free copper and resting temporal EEG rhythms correlate across healthy, mild cognitive impairment, and Alzheimer's disease subjects. Clin Neurophysiol 2007; 118(6): 1244-60
    • (2007) Clin Neurophysiol , vol.118 , Issue.6 , pp. 1244-1260
    • Babiloni, C.1    Squitti, R.2    Del Percio, C.3    Cassetta, E.4    Ventriglia, M.C.5    Ferreri, F.6
  • 140
    • 77649181022 scopus 로고    scopus 로고
    • Copper toxicity in the general population
    • Brewer GJ. Copper toxicity in the general population. Clin Neurophysiol 2010; 121(4): 459-60
    • (2010) Clin Neurophysiol , vol.121 , Issue.4 , pp. 459-460
    • Brewer, G.J.1
  • 141
    • 0026093041 scopus 로고
    • Pharmacology of Curcuma longa
    • Ammon HP, Wahl MA. Pharmacology of Curcuma longa. Planta Med 1991; 57(1): 1-7
    • (1991) Planta Med , vol.57 , Issue.1 , pp. 1-7
    • Ammon, H.P.1    Wahl, M.A.2
  • 142
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
    • Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest 2001; 107(3): 241-6
    • (2001) J Clin Invest , vol.107 , Issue.3 , pp. 241-246
    • Baldwin, A.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.