-
1
-
-
54249103057
-
Drug development based on the metals hypothesis of Alzheimer's disease
-
Bush AI (2008) Drug development based on the metals hypothesis of Alzheimer's disease. J Alzheimers Dis 15, 223-240.
-
(2008)
J Alzheimers Dis
, vol.15
, pp. 223-240
-
-
Bush, A.I.1
-
2
-
-
46149107512
-
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta
-
Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, Deleva K, Lynch T, Kok G, Ritchie CW, Tanzi RE, Cappai R, Masters CL, Barnham KJ, Bush AI (2008) Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta. Neuron 59, 43-55.
-
(2008)
Neuron
, vol.59
, pp. 43-55
-
-
Adlard, P.A.1
Cherny, R.A.2
Finkelstein, D.I.3
Gautier, E.4
Robb, E.5
Cortes, M.6
Volitakis, I.7
Liu, X.8
Smith, J.P.9
Perez, K.10
Laughton, K.11
Li, Q.X.12
Charman, S.A.13
Nicolazzo, J.A.14
Wilkins, S.15
Deleva, K.16
Lynch, T.17
Kok, G.18
Ritchie, C.W.19
Tanzi, R.E.20
Cappai, R.21
Masters, C.L.22
Barnham, K.J.23
Bush, A.I.24
more..
-
3
-
-
46749100924
-
Therapeutics for Alzheimer's disease based on the metal hypothesis
-
Bush AI, Tanzi RE (2008) Therapeutics for Alzheimer's disease based on the metal hypothesis. Neurotherapeutics 5, 421-432.
-
(2008)
Neurotherapeutics
, vol.5
, pp. 421-432
-
-
Bush, A.I.1
Tanzi, R.E.2
-
4
-
-
48949098573
-
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: A phase IIa, double-blind, randomised, placebo-controlled trial
-
Lannfelt L, Blennow K, Zetterberg H, Batsman S, Ames D, Harrison J, Masters CL, Targum S, Bush AI, Murdoch R, Wilson J, Ritchie CW (2008) Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. Lancet Neurol 7, 779-786.
-
(2008)
Lancet Neurol
, vol.7
, pp. 779-786
-
-
Lannfelt, L.1
Blennow, K.2
Zetterberg, H.3
Batsman, S.4
Ames, D.5
Harrison, J.6
Masters, C.L.7
Targum, S.8
Bush, A.I.9
Murdoch, R.10
Wilson, J.11
Ritchie, C.W.12
-
5
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Folstein MF, Katzman R, Price D, Stadlen E (1984) Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.F.3
Katzman, R.4
Price, D.5
Stadlen, E.6
-
7
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B Stat Methodol 57, 289-300.
-
(1995)
J R Stat Soc Series B Stat Methodol
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
8
-
-
31744449380
-
Using the ROC curve for gauging treatment effect in clinical trials
-
Brumback LC, Pepe MS, Alonzo TA (2006) Using the ROC curve for gauging treatment effect in clinical trials. Stat Med 25, 575-590.
-
(2006)
Stat Med
, vol.25
, pp. 575-590
-
-
Brumback, L.C.1
Pepe, M.S.2
Alonzo, T.A.3
-
9
-
-
0016331976
-
Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride
-
Schosinsky KH, Lehmann HP, Beeler MF (1974) Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride. Clin Chem 20, 1556-1563.
-
(1974)
Clin Chem
, vol.20
, pp. 1556-1563
-
-
Schosinsky, K.H.1
Lehmann, H.P.2
Beeler, M.F.3
-
10
-
-
0033950664
-
A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1)
-
Peskin AV, Winterbourn CC (2000) A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1). Clin Chim Acta 293, 157-166.
-
(2000)
Clin Chim Acta
, vol.293
, pp. 157-166
-
-
Peskin, A.V.1
Winterbourn, C.C.2
-
11
-
-
0031883716
-
A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
-
Donepezil Study Group
-
Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT (1998) A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group. Neurology 50, 136-145.
-
(1998)
Neurology
, vol.50
, pp. 136-145
-
-
Rogers, S.L.1
Farlow, M.R.2
Doody, R.S.3
Mohs, R.4
Friedhoff, L.T.5
-
12
-
-
10744224267
-
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting A? amyloid deposition and toxicity in Alzheimer's disease: A pilot phase 2 clinical trial
-
Ritchie CW, Bush AI, Mackinnon A, Macfarlane S, Mastwyk M, MacGregor L, Kiers L, Cherny RA, Li QX, Tammer A, Carrington D,Mavros C,Volitakis I, XilinasM, Ames D, Davis S, Beyreuther K, Tanzi RE, Masters CL (2003) Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting A? amyloid deposition and toxicity in Alzheimer's disease: a pilot phase 2 clinical trial. Arch Neurol 60, 1685-1691.
-
(2003)
Arch Neurol
, vol.60
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
MacKinnon, A.3
MacFarlane, S.4
Mastwyk, M.5
MacGregor, L.6
Kiers, L.7
Cherny, R.A.8
Li, Q.X.9
Tammer, A.10
Carrington, D.11
Mavros, C.12
Volitakis, I.13
Xilinas, M.14
Ames, D.15
Davis, S.16
Beyreuther, K.17
Tanzi, R.E.18
Masters, C.L.19
-
13
-
-
20144371701
-
Excess of serum copper not related to ceruloplasmin in Alzheimer disease
-
Squitti R, Pasqualetti P, Dal Forno G, Moffa F, Cassetta E, Lupoi D, Vernieri F, Rossi L, Baldassini M, Rossini PM (2005) Excess of serum copper not related to ceruloplasmin in Alzheimer disease. Neurology 64, 1040-1046.
-
(2005)
Neurology
, vol.64
, pp. 1040-1046
-
-
Squitti, R.1
Pasqualetti, P.2
Dal Forno, G.3
Moffa, F.4
Cassetta, E.5
Lupoi, D.6
Vernieri, F.7
Rossi, L.8
Baldassini, M.9
Rossini, P.M.10
-
14
-
-
67651204382
-
CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment
-
Mattsson N, Zetterberg H, Hansson O, Andreasen N, Parnetti L, Jonsson M, Herukka SK, van der Flier WM, Blankenstein MA, Ewers M, Rich K, Kaiser E, Verbeek M, Tsolaki M, Mulugeta E, Rosen E, Aarsland D, Visser PJ, Schroder J, Marcusson J, de Leon M, Hampel H, Scheltens P, Pirttila T, Wallin A, Jonhagen ME, Minthon L, Winblad B, Blennow K (2009) CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA 302, 385-393.
-
(2009)
JAMA
, vol.302
, pp. 385-393
-
-
Mattsson, N.1
Zetterberg, H.2
Hansson, O.3
Andreasen, N.4
Parnetti, L.5
Jonsson, M.6
Herukka, S.K.7
Van Der Flier, W.M.8
Ma, B.9
Ewers, M.10
Rich, K.11
Kaiser, E.12
Verbeek, M.13
Tsolaki, M.14
Mulugeta, E.15
Rosen, E.16
Aarsland, D.17
Visser, P.J.18
Schroder, J.19
Marcusson, J.20
De Leon, M.21
Hampel, H.22
Scheltens, P.23
Pirttila, T.24
Wallin, A.25
Jonhagen, M.E.26
Minthon, L.27
Winblad, B.28
Blennow, K.29
more..
-
15
-
-
34548689646
-
Alzhemed: A potential treatment for Alzheimer's disease
-
DOI 10.2174/156720507781788882
-
Aisen PS, Gauthier S, Vellas B, Briand R, Saumier D, Laurin J, Garceau D (2007) Alzhemed: a potential treatment for Alzheimer's disease. Curr Alzheimer Res 4, 473-478. (Pubitemid 47416642)
-
(2007)
Current Alzheimer Research
, vol.4
, Issue.4
, pp. 473-478
-
-
Aisen, P.S.1
Gauthier, S.2
Vellas, B.3
Briand, R.4
Saumier, D.5
Laurin, J.6
Garceau, D.7
-
16
-
-
73349091534
-
A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
-
Salloway S, Sperling R, Gilman S, Fox NC, Blennow K, Raskind M, Sabbagh M, Honig LS, Doody R, van Dyck CH, Mulnard R, Barakos J, Gregg KM, Liu E, Lieberburg I, Schenk D, Black R, Grundman M (2009) A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology 73, 2061-2070.
-
(2009)
Neurology
, vol.73
, pp. 2061-2070
-
-
Salloway, S.1
Sperling, R.2
Gilman, S.3
Fox, N.C.4
Blennow, K.5
Raskind, M.6
Sabbagh, M.7
Honig, L.S.8
Doody, R.9
Van Dyck, C.H.10
Mulnard, R.11
Barakos, J.12
Gregg, K.M.13
Liu, E.14
Lieberburg, I.15
Schenk, D.16
Black, R.17
Grundman, M.18
-
17
-
-
72549105935
-
Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: A randomized controlled trial
-
for the Tarenflurbil Phase 3 Study Group
-
Green RC, Schneider LS, Amato DA, Beelen AP, Wilcock G, Swabb EA, Zavitz KH, for the Tarenflurbil Phase 3 Study Group (2009) Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial. JAMA 302, 2557-2564.
-
(2009)
JAMA
, vol.302
, pp. 2557-2564
-
-
Green, R.C.1
Schneider, L.S.2
Amato, D.A.3
Beelen, A.P.4
Wilcock, G.5
Swabb, E.A.6
Zavitz, K.H.7
-
18
-
-
34548639338
-
A neuropsychological test battery for use in Alzheimer disease clinical trials
-
Harrison J, Minassian SL, Jenkins L, Black RS, Koller M, Grundman M (2007) A neuropsychological test battery for use in Alzheimer disease clinical trials. Arch Neurol 64, 1323-1329.
-
(2007)
Arch Neurol
, vol.64
, pp. 1323-1329
-
-
Harrison, J.1
Minassian, S.L.2
Jenkins, L.3
Black, R.S.4
Koller, M.5
Grundman, M.6
-
19
-
-
77954467734
-
A Comparison of the Neuropsychological Test Battery (NTB) and ADAS-Cog Based on Alzheimerfls Disease Clinical Trials
-
Vienna
-
Black R, Harrison J, Li D, Yang L, Booth K, Barlas S (2009). A Comparison of the Neuropsychological Test Battery (NTB) and ADAS-Cog Based on Alzheimerfls Disease Clinical Trials. In: International Conference on Alzheimer' s Disease. Vienna, P4-089.
-
(2009)
International Conference on Alzheimer' S Disease
-
-
Black, R.1
Harrison, J.2
Li, D.3
Yang, L.4
Booth, K.5
Barlas, S.6
|