Evolutionary genetics evidence of an essential, nonredundant role of the IFN-γ pathway in protective immunity

Human Mutation

Volumn 32, Issue 6, 2011, Pages 633-642

  Manry, Jérémy ^a,b   Laval, Guillaume ^a,b   Patin, Etienne ^a,b   Fornarino, Simona ^a,b   Tichit, Magali ^a   Bouchier, Christiane ^a   Barreiro, Luis B ^c   Quintana Murci, Lluis ^a,b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

IFNG; IFNGR1; IFNGR2; Natural selection; Polymorphisms; Population genetics

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; GAMMA INTERFERON RECEPTOR 1; GAMMA INTERFERON RECEPTOR 2; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL ARTICLE; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC VARIABILITY; HUMAN; IMMUNITY; INTERFERON PRODUCTION; PATHOGENESIS; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN FUNCTION;

AFRICA SOUTH OF THE SAHARA; EUROPE; EVOLUTION, MOLECULAR; EXONS; FAR EAST; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNITY; INFECTION; INTERFERON-GAMMA; MYCOBACTERIUM INFECTIONS; MYCOBACTERIUM TUBERCULOSIS; POPULATION; RECEPTORS, INTERFERON; SELECTION, GENETIC;

CORYNEBACTERINEAE;

EID: 79957597037     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21484     Document Type: Article

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