A single nucleotide polymorphism in the first intron of the human IFN-γ gene: Absolute correlation with a polymorphic CA microsatellite marker of high IFN-γ production

Human Immunology

Volumn 61, Issue 9, 2000, Pages 863-866

  Pravica, Vera ^a   Perrey, Chris ^a   Stevens, Adam ^a   Lee, Jar How ^b   Hutchinson, Ian V ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b One Lambda Inc   (United States)

Author keywords

Functional polymorphism; Human IFN gene

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICROSATELLITE DNA;

ALLELE; ARTICLE; BINDING SITE; CORRELATION FUNCTION; DNA POLYMORPHISM; GRAFT REJECTION; HUMAN; IN VITRO STUDY; INTERFERON PRODUCTION; INTRON; LUNG FIBROSIS; LUNG TRANSPLANTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

HELA CELLS; HUMAN; INTERFERON TYPE II; INTRONS; MICROSATELLITE REPEATS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 0033787711     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(00)00167-1     Document Type: Article

References (7)

1. Association of polymorphism in the interferon gamma gene with IDDM
2. Analysis of an interferon gamma gene (IFNG) polymorphism in Danish and Finnish insulin-dependent diabetes mellitus (IDDM) patients and control subjects. Danish Study Group of diabetes in childhood
3. In vitro production of IFN-γ correlates with CA repeat polymorphism in the human IFN-γ gene
4. CA repeat allele polymorphism in the first intron of the human interferon-γ gene is associated with lung allograft fibrosis
5. ARMS-PCR technologies to determine IL-10, TNFalpha, TNF-beta and TGF-betal gene polymorphisms
6. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL
7. The c-rel protooncogene product c-Rel but not NF-κB binds to the intronic region of the human interferon-γ gene at a site related to and interferon-stimulable response element