Interferon-γ and interleukin-10 gene polymorphisms in pulmonary tuberculosis

American Journal of Respiratory and Critical Care Medicine

Volumn 167, Issue 7, 2003, Pages 970-975

  López Maderuelo, Dolores ^b   Arnalich, Francisco ^a   Serantes, Rocio ^b   González, Alicia ^b   Codoceo, Rosa ^b   Madero, Rosario ^b   Vázquez, Juan J ^b   Montiel, Carmen ^b  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b NONE

Author keywords

Cytokine production; Gene polymorphisms; Interferon ; Interleukin 10; Tuberculosis susceptibility

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; TUBERCULIN;

ADULT; AGED; ALLELE; ARTICLE; BLOOD CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURAL ANTHROPOLOGY; CYTOKINE PRODUCTION; DISEASE COURSE; FEMALE; GENE IDENTIFICATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; INFECTION SENSITIVITY; INTRON; LUNG TUBERCULOSIS; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; MULTIVARIATE ANALYSIS; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; POPULATION RESEARCH; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; RISK FACTOR; STIMULATION; TUBERCULIN TEST;

ADULT; AGED; ALLELES; FEMALE; GENE FREQUENCY; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; LYMPHOCYTES; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; PROMOTER REGIONS (GENETICS); TUBERCULOSIS, PULMONARY;

EID: 0345421272     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200205-438BC     Document Type: Article

References (30)

1. Bellamy R, Beyers N, McAdam KPWJ, Ruwende C, Gie R, Samaai P, Bester D, Meyer M, Corrah T, Collin M, et al. Genetic susceptibility to tuberculosis in Africans: a genome-wide scan. Proc Natl Acad Sci USA 2000;97:8005-8009.
2. Bellamy R, Ruwende C, Corrah T, McAdam KPWJ, Whittle HC, Hill AVS. Assessment of the interleukin 1 gene cluster and other candidate gene polymorphisms in host susceptibility to tuberculosis. Tuber Lung Dis 1998;79:83-89.
3. Bellamy R, Ruwende C, Corrah T, McAdam KPWJ, Whittle HC, Hill AVS. Variation in the NRAMPI gene and susceptibility to tuberculosis in West Africans. N Engl J Med 1998;338:640-644.
4. Bellamy R, Ruwende C, Corrah T, McAdam KPWJ, Thursz M, Whittle HC, Hill AVS. Resistance to tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene. J Infect Dis 1999;179:721-724.
5. Wilkinson RJ, Patel P, Llewelyn M, Hirsch CS, Pasvol G, Snounou G, Davidson RN, Toossi Z. Influence of polymorphism in the genes for the interleukin (IL)-1 receptor antagonist and IL-1β on tuberculosis. J Exp Med 1999;189:1863-1873.
6. Hill AV. The immunogenetics of human infectious diseases. Annu Rev Immunol 1998;16:593-617.
7. Flynn J, Chan J, Triebold KJ, Dalton DK, Stewart TA, Bloom BR. An essential role for interferon-γ in resistance to Mycobacterium tuberculosis infection. J Exp Med 1993;178:2249-2254.
8. Newport MJ, Huxley CM, Huston S, Hawrylowicz CM, Oostra BA, Williamson R, Levin M. A mutation in the IFN-γ receptor gene and susceptibility to mycobacterial infection. N Engl J Med 1996;335:1941-1949.
9. Jouanguy E, Altare F, Lamhamendi S, Revy P, Emile JF, Newport M, Levin M, Blanche S, Sebouin E, Fischer A, et al. IFN-γ receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. N Engl J Med 1996;335:1956-1961.
10. Förtsch D, Röllinghoff M, Stenger S. IL-10 converts human dendritic cells into macrophage-like cells with increased antibacterial activity against virulent Mycobacterium tuberculosis. J Immunol 2000;165:978-987.
11. Khani-Hanjani A, Lacalle D, Hoar D, Chalmers A, Horsman D, Anderson M, Balshaw R, Keown PA. Association between dinucleotide repeat in non-coding region of interferon-gamma gene and susceptibility to, and severity of, rheumatoid arthritis. Lancet 2000;356:820-825.
12. Pravica V, Asderakis A, Perrey C, Hajeer A, Sinnott PJ, Hutchinson IV. In vitro production of IFN-γ correlates with CA repeat polymorphism in the human IFN-γ gene. Eur J Immunogenet 1999;25:1-3.
13. Pravica V, Perrey C, Stevens A, Lee JH, Hutchinson IV. A single nucleotide polymorphism in the first intron of the human IFN-γ gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-γ production. Hum Immunol 2000;61:863-866.
14. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997;24:1-8.
15. National Tuberculosis and Respiratory Disease Association. Diagnostic standards and classification of tuberculosis. New York: National Tuberculosis and Respiratory Disease Association; 1969.
16. 2+ channels, derived from mRNA identification studies. FEBS Lett 2000;481:235-239.
17. Perrey C, Turner SJ, Pravica V, Howell WM, Hutchinson IV. ARMSPCR methodologies to determine IL-10, TNF-α, TNF-β and TGF-β1 gene polymorphisms. Transpl Immunol 1999;7:127-128.
18. Arnalich F, Hernanz A, Vázquez JJ, Amores A. Cell-mediated immune response and cytokine production in idiopathic senile anorexia. Mech Ageing Dev 1994;77:67-74.
19. Arnalich F, Lopez-Maderuelo D, Codoceo R, Lopez J, Solis-Garrido LM, Capiscol C, Fernandez-Capitan C, Madero R, Montiel C. Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis. Clin Exp Immunol 2002;127:331-336.
20. Lang TA, Secic M. How to report statistics in medicine. Philadelphia: American College of Physicians; 1997.
21. Lio D, Marino V, Serauto A, Gioia V, Scola L, Crivello A, Forte GI, Colonna-Romano G, Candore G, Caruso C. Genotype frequencies of the +874T→A single nucleotide polymorphism in the first intron of the interferon-gamma gene in a sample of Sicilian patients affected by tuberculosis. Eur J Immunogenet 2002;29:371-374.
22. Sánchez FO, Rodriguez JI, Agudelo G, Garcia LF. Immune responsiveness and lymphokine production in patients with tuberculosis and healthy controls. Infect Immun 1994;62:5673-5678.
23. Zhang M, Lin Y, Iyer DV, Gong J, Abrams JS, Barnes PF. T cell cytokine responses in human infection with Mycobacterium tuberculosis. Infect Immun 1995;63:3231-3234.
24. Sodhi A, Gong J-H, Silva C, Qian D, Barnes PF. Clinical correlates of interferon γ production in patients with tuberculosis. Clin Infect Dis 1997;25:617-620.
25. Heinemeyer T, Wingender E, Reuter I, Hermjakob H, Kel AE, Kel OV, Ignatieva EV, Ananko EA, Podkolodnaya OA, Kolpakov FA, et al. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Res 1998;26:362-367.
26. Barnes PF, Shuzhuang LU, Abrams JS, Wang E, Yamamura M, Modlin RL. Cytokine production at the site of disease in human tuberculosis. Infect Immun 1993;61:3482-3489.
27. Lin Y, Zhang M, Hofman FM, Gong J, Barnes PF. Absence of a prominent Th2 response in human tuberculosis. Infect Immun 1996;64:1351-1356.
28. Hirsch CS, Toossi Z, Johnson JL, Luzze H, Nitambi L, Peters P, Mchugh M, Okwera A, Jobba M, Mugvenvi P, et al. Augmentation of apoptosis and interferon-γ production at sites of active mycobacterium tuberculosis infection in human tuberculosis. J Infect Dis 2001;183:779-788.
29. Boussiotis VA, Tsai EY, Yunis E, Thim S, Delgado JC, Dascher CC, Berezovskaya A, Rousset D, Reynes JM, Goldfeld AE. IL-10 producing T cells suppress immune responses in anergic tuberculosis patients. J Clin Invest 2000;105:1317-1325.
30. Delgado JC, Baena A, Thim S, Goldfeld AE. Ethnic-specific genetic associations with pulmonary tuberculosis. J Infect Dis 2002;186:1463-1468.