Macrophage activation by factors released from acetaminophen-injured hepatocytes: Potential role of HMGB1

Toxicology and Applied Pharmacology

Volumn 253, Issue 3, 2011, Pages 170-177

  Dragomir, Ana Cristina ^a   Laskin, Jeffrey D ^b   Laskin, Debra L ^a  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Acetaminophen; High mobility group box 1; Liver; Macrophages; Reactive oxygen species

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; CYCLOOXYGENASE 2; HEME OXYGENASE 1; HIGH MOBILITY GROUP B1 PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PARACETAMOL; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; LIVER; LIVER CELL DAMAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; CHEMOKINE CCL2; CYCLOOXYGENASE 2; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEME OXYGENASE-1; HEPATOCYTES; HMGB1 PROTEIN; MACROPHAGE ACTIVATION; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL;

EID: 79956326320     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.04.003     Document Type: Article

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