High-mobility group box 1 contributes to lethality of endotoxemia in heme oxygenase-1-deficient mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 41, Issue 2, 2009, Pages 129-135

  Takamiya, Rina ^a,b,d   Hung, Chi Chih ^a   Hall, Sean R ^a   Fukunaga, Koichi ^a,b   Nagaishi, Takashi ^a,c   Maeno, Toshitaka ^a   Owen, Caroline ^a   Macias, Alvaro A ^a   Fredenburgh, Laura E ^a   Ishizaka, Akitoshi ^b   Blumberg, Richard S ^a   Baron, Rebecca M ^a   Perrella, Mark A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b KEIO UNIVERSITY   (Japan)

^c Tokyo Medical and Dental University ^*  (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Endotoxemia; Heme oxygenase 1; High mobility group box 1; Inflammation; Oxidative stress

Indexed keywords

BILIVERDIN; CARBON MONOXIDE; HEME; HEME OXYGENASE 1; HIGH MOBILITY GROUP B1 PROTEIN; LIPOPOLYSACCHARIDE; NEUTRALIZING ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL MIGRATION; CELL PROTECTION; CONTROLLED STUDY; ENDOTOXEMIA; ENZYME DEFICIENCY; INFLAMMATORY CELL; MORTALITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ANIMALS; BILIVERDINE; CARBON MONOXIDE; CELL MOVEMENT; CELLS, CULTURED; ENDOTOXEMIA; FEMALE; HEME OXYGENASE-1; HMGB1 PROTEIN; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NEUTROPHILS; SURVIVAL RATE;

MUS;

EID: 67651171360     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2008-0331OC     Document Type: Article

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