-
1
-
-
0033552883
-
Atherosclerosis - an inflammatory disease
-
Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999, 340:115-126.
-
(1999)
N Engl J Med
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
2
-
-
0036852744
-
The macrophage foam cell as a target for therapeutic intervention
-
Li A.C., Glass C.K. The macrophage foam cell as a target for therapeutic intervention. Nat Med 2002, 8:1235-1242.
-
(2002)
Nat Med
, vol.8
, pp. 1235-1242
-
-
Li, A.C.1
Glass, C.K.2
-
3
-
-
0022549920
-
A receptor-mediated pathway for cholesterol homeostasis
-
Brown M.S., Goldstein J.L. A receptor-mediated pathway for cholesterol homeostasis. Science 1986, 232:34-47.
-
(1986)
Science
, vol.232
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
4
-
-
0035170229
-
High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport
-
von Eckardstein A., Nofer J.R., Assmann G. High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport. Arterioscl Thromb Vasc Biol 2001, 21:13-27.
-
(2001)
Arterioscl Thromb Vasc Biol
, vol.21
, pp. 13-27
-
-
von Eckardstein, A.1
Nofer, J.R.2
Assmann, G.3
-
5
-
-
0032851111
-
Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway
-
Edwards P.A., Ericsson J. Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway. Annu Rev Biochem 1999, 68:157-185.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 157-185
-
-
Edwards, P.A.1
Ericsson, J.2
-
6
-
-
0035843962
-
Structural mechanism for statin inhibition of HMG-CoA reductase
-
Istvan E.S., Deisenhofer J. Structural mechanism for statin inhibition of HMG-CoA reductase. Science 2001, 292:1160-1164.
-
(2001)
Science
, vol.292
, pp. 1160-1164
-
-
Istvan, E.S.1
Deisenhofer, J.2
-
7
-
-
0019135838
-
Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth
-
Brown M.S., Goldstein J.L. Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. J Lipid Res 1980, 21:505-517.
-
(1980)
J Lipid Res
, vol.21
, pp. 505-517
-
-
Brown, M.S.1
Goldstein, J.L.2
-
8
-
-
4244005749
-
Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygote
-
Bilheimer D.W., Grundy S.M., Brown M.S., Goldstein J.L. Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygote. Proc Natl Acad Sci U S A 1989, 80:4142-4228.
-
(1989)
Proc Natl Acad Sci U S A
, vol.80
, pp. 4142-4228
-
-
Bilheimer, D.W.1
Grundy, S.M.2
Brown, M.S.3
Goldstein, J.L.4
-
9
-
-
0034644537
-
Ras and Rho GTPases: a family reunion
-
Bar-Sagi D., Hall A. Ras and Rho GTPases: a family reunion. Cell 2000, 103:227-238.
-
(2000)
Cell
, vol.103
, pp. 227-238
-
-
Bar-Sagi, D.1
Hall, A.2
-
10
-
-
0034672686
-
Functional aspects of polyisoprenoid protein substituents: roles in protein-protein interaction and trafficking
-
Sinensky M. Functional aspects of polyisoprenoid protein substituents: roles in protein-protein interaction and trafficking. Biochem Biophys Acta 2000, 1529:203-209.
-
(2000)
Biochem Biophys Acta
, vol.1529
, pp. 203-209
-
-
Sinensky, M.1
-
11
-
-
0032844429
-
1999. Antiatherogenic properties of naringenin, a citrus flavonoid
-
Wilcox L.J., Borradaile N.M., Huff M.W. 1999. Antiatherogenic properties of naringenin, a citrus flavonoid. Cardiovasc Drug Rev 1999, 17:160-178.
-
(1999)
Cardiovasc Drug Rev
, vol.17
, pp. 160-178
-
-
Wilcox, L.J.1
Borradaile, N.M.2
Huff, M.W.3
-
12
-
-
0038776380
-
Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma
-
Hu E., Kim J.B., Sarraf P., Spiegelman B.M. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma. Science 1996, 274:2100-2103.
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Spiegelman, B.M.4
-
13
-
-
0030885520
-
The orphan nuclear receptor LXRα is positively and negatively regulated by distinct products of mevalonate metabolism
-
Forman B.M., Ruan B., Chen J., Schroepfer G.J.J., Evans R.M. The orphan nuclear receptor LXRα is positively and negatively regulated by distinct products of mevalonate metabolism. Proc Natl Acad Sci U S A 1997, 94:10588-10593.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10588-10593
-
-
Forman, B.M.1
Ruan, B.2
Chen, J.3
Schroepfer, G.J.J.4
Evans, R.M.5
-
14
-
-
0030840424
-
Tissue expression studies on the mouse acyl-CoA:cholesterol acyltransferase gene (Acact): findings supporting the existence of multiple cholesterol esterification enzymes in mice
-
Meiner V.L., Tam C., Gunn M.D., Farese R.V. Tissue expression studies on the mouse acyl-CoA:cholesterol acyltransferase gene (Acact): findings supporting the existence of multiple cholesterol esterification enzymes in mice. J Lipid Res 1997, 38:1928-1933.
-
(1997)
J Lipid Res
, vol.38
, pp. 1928-1933
-
-
Meiner, V.L.1
Tam, C.2
Gunn, M.D.3
Farese, R.V.4
-
15
-
-
0036321948
-
ATP-binding cassette transporter A1 and cholesterol trafficking
-
Oram J.F. ATP-binding cassette transporter A1 and cholesterol trafficking. Curr Opin Lipidol 2002, 13:373-381.
-
(2002)
Curr Opin Lipidol
, vol.13
, pp. 373-381
-
-
Oram, J.F.1
-
16
-
-
69549129239
-
PPARγ1-induced caveolin-1 enhances cholesterol efflux and attenuates atherosclerosis in apolipoprotein E-deficient mice
-
Hu Q., Zhang X.J., Liu C.X., Wang X.P., Zhang Y. PPARγ1-induced caveolin-1 enhances cholesterol efflux and attenuates atherosclerosis in apolipoprotein E-deficient mice. J Vasc Res 2010, 47:69-79.
-
(2010)
J Vasc Res
, vol.47
, pp. 69-79
-
-
Hu, Q.1
Zhang, X.J.2
Liu, C.X.3
Wang, X.P.4
Zhang, Y.5
-
17
-
-
0035138625
-
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
-
Chinetti G., Lestavel S., Bocher V., Remaley A.T., Neve B., Torra I.P., et al. PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med 2001, 7:53-58.
-
(2001)
Nat Med
, vol.7
, pp. 53-58
-
-
Chinetti, G.1
Lestavel, S.2
Bocher, V.3
Remaley, A.T.4
Neve, B.5
Torra, I.P.6
-
18
-
-
17744376173
-
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
-
Chawla A., Boisvert W.A., Lee C.H., Laffitte B.A., Barak Y., Joseph S.B., et al. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell 2001, 7:161-171.
-
(2001)
Mol Cell
, vol.7
, pp. 161-171
-
-
Chawla, A.1
Boisvert, W.A.2
Lee, C.H.3
Laffitte, B.A.4
Barak, Y.5
Joseph, S.B.6
-
19
-
-
0037343227
-
Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins
-
Argmann C.A., Sawyez C.G., McNeil C.J., Hegele R.A., Huff M.W. Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins. Arterioscler Thromb Vasc Biol 2003, 23:475-482.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 475-482
-
-
Argmann, C.A.1
Sawyez, C.G.2
McNeil, C.J.3
Hegele, R.A.4
Huff, M.W.5
-
20
-
-
0036845525
-
Lycopene tomatoes and the prevention of coronary heart disease
-
Rao A.V. Lycopene tomatoes and the prevention of coronary heart disease. Exp Biol Med 2002, 227:908-913.
-
(2002)
Exp Biol Med
, vol.227
, pp. 908-913
-
-
Rao, A.V.1
-
21
-
-
0036846616
-
Overview of mechanism of action of lycopene
-
Heber D., Lu Q.Y. Overview of mechanism of action of lycopene. Exp Biol Med 2002, 227:920-923.
-
(2002)
Exp Biol Med
, vol.227
, pp. 920-923
-
-
Heber, D.1
Lu, Q.Y.2
-
22
-
-
0028980890
-
Effect of β-carotene on the expression of 3-hydroxy-3-methylglutariyl coenzyme A reductase in rat liver
-
Moreno F.S., Rossiello M.R., Manjeshwar S., Nath R., Rao P.M., Rajalakshmi S., et al. Effect of β-carotene on the expression of 3-hydroxy-3-methylglutariyl coenzyme A reductase in rat liver. Cancer Letters 1995, 96:201-208.
-
(1995)
Cancer Letters
, vol.96
, pp. 201-208
-
-
Moreno, F.S.1
Rossiello, M.R.2
Manjeshwar, S.3
Nath, R.4
Rao, P.M.5
Rajalakshmi, S.6
-
23
-
-
0031589211
-
Hypocholesterolemic effect of lycopene and β-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophage
-
Fuhrman B., Elis A., Aviram M. Hypocholesterolemic effect of lycopene and β-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophage. Biochem Biophys Res Com 1997, 223:658-662.
-
(1997)
Biochem Biophys Res Com
, vol.223
, pp. 658-662
-
-
Fuhrman, B.1
Elis, A.2
Aviram, M.3
-
24
-
-
0032868926
-
Isoprenoid-mediated inhibition of mevalonate synthesis: potential application to cancer
-
Elson C.E., Peffley D.M., Hentosh P., Mo H. Isoprenoid-mediated inhibition of mevalonate synthesis: potential application to cancer. Proc Soc Exp Biol Med 1999, 22:294-310.
-
(1999)
Proc Soc Exp Biol Med
, vol.22
, pp. 294-310
-
-
Elson, C.E.1
Peffley, D.M.2
Hentosh, P.3
Mo, H.4
-
25
-
-
54149115153
-
Activation of the adenosine-A3 receptor stimulates matrix metalloproteinase-9 secretion by macrophages
-
Velot E., Haas B., Léonard F., Ernens I., Rolland-Turner M., Schwartz C., et al. Activation of the adenosine-A3 receptor stimulates matrix metalloproteinase-9 secretion by macrophages. Cardiovasc Res Issue 2008, 80:246-254.
-
(2008)
Cardiovasc Res Issue
, vol.80
, pp. 246-254
-
-
Velot, E.1
Haas, B.2
Léonard, F.3
Ernens, I.4
Rolland-Turner, M.5
Schwartz, C.6
-
26
-
-
0027958282
-
Evaluation of the analysis of cholesterol oxides by liquid chromatography
-
Chen B.H., Chen Y.C. Evaluation of the analysis of cholesterol oxides by liquid chromatography. J Chromatography A 1994, 661:127-136.
-
(1994)
J Chromatography A
, vol.661
, pp. 127-136
-
-
Chen, B.H.1
Chen, Y.C.2
-
27
-
-
80053124592
-
Hydroxymethylglutaryl-CoA reductase in plants
-
CRC Press, Boca Raton (Fla), J.R. Sabine (Ed.)
-
Garg V.K., Douglas T.J. Hydroxymethylglutaryl-CoA reductase in plants. Hydroxymethylglutaryl coenzyme A reductase 1983, 29-37. CRC Press, Boca Raton (Fla). J.R. Sabine (Ed.).
-
(1983)
Hydroxymethylglutaryl coenzyme A reductase
, pp. 29-37
-
-
Garg, V.K.1
Douglas, T.J.2
-
28
-
-
0037229435
-
Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at the post-transcriptional level
-
Peffley D.M., Gayen A.K. Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at the post-transcriptional level. J Nutr 2003, 133:38-44.
-
(2003)
J Nutr
, vol.133
, pp. 38-44
-
-
Peffley, D.M.1
Gayen, A.K.2
-
29
-
-
33645509662
-
Dietary lycopene downregulates carotenoid 15,15'-monooxygenase and PPAR-gamma in selected rat tissues
-
Zaripheh S., Nara T.Y., Nakamura M.T., Erdman J.W. Dietary lycopene downregulates carotenoid 15,15'-monooxygenase and PPAR-gamma in selected rat tissues. J Nutr 2006, 136:932-938.
-
(2006)
J Nutr
, vol.136
, pp. 932-938
-
-
Zaripheh, S.1
Nara, T.Y.2
Nakamura, M.T.3
Erdman, J.W.4
-
30
-
-
24144467460
-
Upregulation of connexin 43 by retinoids but not by non-provitamin A carotenoids requires RARs
-
Vine A.L., Bertram J.S. Upregulation of connexin 43 by retinoids but not by non-provitamin A carotenoids requires RARs. Nutr Cancer 2005, 52:105-113.
-
(2005)
Nutr Cancer
, vol.52
, pp. 105-113
-
-
Vine, A.L.1
Bertram, J.S.2
-
31
-
-
4344670930
-
Carotenoids and transcription
-
Sharoni Y., Danilenko M., Dubi N., Ben-Dor A., Levy J. Carotenoids and transcription. Arch Biochem Biophys 2004, 430:89-96.
-
(2004)
Arch Biochem Biophys
, vol.430
, pp. 89-96
-
-
Sharoni, Y.1
Danilenko, M.2
Dubi, N.3
Ben-Dor, A.4
Levy, J.5
-
32
-
-
36049032810
-
β-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor γ expression and reactive oxygen species production in MCF-7 cancer cells
-
Cui Y., Lu Z., Baia L., Shi Z., Zhao W.E., Zhao B. β-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor γ expression and reactive oxygen species production in MCF-7 cancer cells. Eur J Cancer 2007, 43:2590-2601.
-
(2007)
Eur J Cancer
, vol.43
, pp. 2590-2601
-
-
Cui, Y.1
Lu, Z.2
Baia, L.3
Shi, Z.4
Zhao, W.E.5
Zhao, B.6
-
33
-
-
1842424448
-
Liver X receptors as potential therapeutic targets for multiple diseases
-
Cao G., Liang Y., Jiang X.C., Eacho P.I. Liver X receptors as potential therapeutic targets for multiple diseases. Drug News Perspect 2004, 17:35-41.
-
(2004)
Drug News Perspect
, vol.17
, pp. 35-41
-
-
Cao, G.1
Liang, Y.2
Jiang, X.C.3
Eacho, P.I.4
-
34
-
-
0037243138
-
Caveolins and macrophage lipid metabolism
-
Gargalovic P., Ladislav D. Caveolins and macrophage lipid metabolism. Lipid Res 2003, 44:11-21.
-
(2003)
Lipid Res
, vol.44
, pp. 11-21
-
-
Gargalovic, P.1
Ladislav, D.2
-
35
-
-
0035963902
-
Caveolae and intracellular trafficking of cholesterol
-
Fielding C.J., Fielding P.E. Caveolae and intracellular trafficking of cholesterol. Adv Drug Deliv Rev 2001, 49:251-264.
-
(2001)
Adv Drug Deliv Rev
, vol.49
, pp. 251-264
-
-
Fielding, C.J.1
Fielding, P.E.2
-
36
-
-
26444537961
-
Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 Cells treated with ezetimibe
-
During A., Dawson H.D., Harrison E.H. Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 Cells treated with ezetimibe. J Nutr 2005, 135:2305-2312.
-
(2005)
J Nutr
, vol.135
, pp. 2305-2312
-
-
During, A.1
Dawson, H.D.2
Harrison, E.H.3
-
37
-
-
0035136940
-
Progress in cardiovascular biology: PPAR for the course
-
Lazar M.A. Progress in cardiovascular biology: PPAR for the course. Nat Med 2001, 7:23-24.
-
(2001)
Nat Med
, vol.7
, pp. 23-24
-
-
Lazar, M.A.1
-
38
-
-
0037663317
-
Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells
-
Burgermeister E., Tencer L., Liscocitch M. Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells. Oncogene 2003, 22:3888-3900.
-
(2003)
Oncogene
, vol.22
, pp. 3888-3900
-
-
Burgermeister, E.1
Tencer, L.2
Liscocitch, M.3
-
39
-
-
21644434629
-
Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism
-
Llaverias G., Vazquez-Carrera M., Sanchez R.M., Noe V., Ciudad C.J., Laguna J.C., et al. Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism. J Lipid Res 2004, 45:2015-2024.
-
(2004)
J Lipid Res
, vol.45
, pp. 2015-2024
-
-
Llaverias, G.1
Vazquez-Carrera, M.2
Sanchez, R.M.3
Noe, V.4
Ciudad, C.J.5
Laguna, J.C.6
-
40
-
-
34250188856
-
β-Cryptoxanthin, a novel natural RAR ligand, induces ATP-binding cassette transporters in macrophages
-
Matsumoto A., Mizukami H., Mizuno S., Umegaki K., Nishikawa J., Shudo K., et al. β-Cryptoxanthin, a novel natural RAR ligand, induces ATP-binding cassette transporters in macrophages. Biochem Pharmacol. 2007, 74:256-264.
-
(2007)
Biochem Pharmacol.
, vol.74
, pp. 256-264
-
-
Matsumoto, A.1
Mizukami, H.2
Mizuno, S.3
Umegaki, K.4
Nishikawa, J.5
Shudo, K.6
-
41
-
-
0032540012
-
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz P., Nagy L., Alvarez J.G., Thomazy V.A., Evans R.M. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998, 93:241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.3
Thomazy, V.A.4
Evans, R.M.5
-
42
-
-
0032842826
-
Coexpression of scavenger receptor-BI and caveolin-1 is associated with an enhanced selective cholesteryl ester uptake in THP-1 macrophages
-
Matveev S., van der Westhuyzen D.R., Smart E.J. Coexpression of scavenger receptor-BI and caveolin-1 is associated with an enhanced selective cholesteryl ester uptake in THP-1 macrophages. J Lipid Res 1999, 40:1647-1654.
-
(1999)
J Lipid Res
, vol.40
, pp. 1647-1654
-
-
Matveev, S.1
van der Westhuyzen, D.R.2
Smart, E.J.3
-
43
-
-
0031893929
-
Activation of protein kinase C-zeta and phosphatidylinositol 3'-kinase and promotion of macrophage differentiation by insulin-like growth factor-I
-
Liu Q., Ning W., Dantzer R., Freund G.G., Kelly K.W. Activation of protein kinase C-zeta and phosphatidylinositol 3'-kinase and promotion of macrophage differentiation by insulin-like growth factor-I. J Immunol 1998, 160:1393-1401.
-
(1998)
J Immunol
, vol.160
, pp. 1393-1401
-
-
Liu, Q.1
Ning, W.2
Dantzer, R.3
Freund, G.G.4
Kelly, K.W.5
-
44
-
-
0033817671
-
Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male non-smokers
-
Hughes D.A., Wright A.J., Finglas P.M., Polley A.C., Bailey A.L., Astlev S.V., et al. Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male non-smokers. J Infect Dis 2000, 182:11-15.
-
(2000)
J Infect Dis
, vol.182
, pp. 11-15
-
-
Hughes, D.A.1
Wright, A.J.2
Finglas, P.M.3
Polley, A.C.4
Bailey, A.L.5
Astlev, S.V.6
|