-
1
-
-
0036012793
-
Nuclear hormone receptors and cholesterol trafficking: The orphans find a new home
-
Fitzgerald ML, Moore KJ, Freeman MW. Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home. J Mol Med. 2002;80:271-281.
-
(2002)
J Mol Med
, vol.80
, pp. 271-281
-
-
Fitzgerald, M.L.1
Moore, K.J.2
Freeman, M.W.3
-
3
-
-
0028972025
-
15-Deoxy-δ 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR γ
-
Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. 15-Deoxy-δ 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR γ. Cell. 1995;83:803-812.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
4
-
-
0031886864
-
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature. 1998;391:79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
5
-
-
0036521594
-
The role of PPARs in inflammation and immunity
-
Clark RB. The role of PPARs in inflammation and immunity. J Leukocyte Biol. 2002;71:388-400.
-
(2002)
J Leukocyte Biol
, vol.71
, pp. 388-400
-
-
Clark, R.B.1
-
6
-
-
0031888958
-
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang C, Ting AT, Seed B. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature. 1998;391:82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
7
-
-
0032540012
-
PPARγ promotes monocytelmacrophage differentiation and uptake of oxidized LDL
-
Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARγ promotes monocytelmacrophage differentiation and uptake of oxidized LDL. Cell. 1998;93:241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.3
Thomazy, V.A.4
Evans, R.M.5
-
8
-
-
0036094913
-
Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atheroslcerosis
-
Barbier O, Torra IP, Duguay Y, Blanquart C, Fruchart J-C, Glineur C, Staels B. Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atheroslcerosis. Arterioscler Thromb Vasc Biol. 2002;22:717-726.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 717-726
-
-
Barbier, O.1
Torra, I.P.2
Duguay, Y.3
Blanquart, C.4
Fruchart, J.-C.5
Glineur, C.6
Staels, B.7
-
9
-
-
0032560545
-
Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
-
Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, Witztum JL, Auwerx J, Palinski W, Glass CK. Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1998;95:7614-7619.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7614-7619
-
-
Ricote, M.1
Huang, J.2
Fajas, L.3
Li, A.4
Welch, J.5
Najib, J.6
Witztum, J.L.7
Auwerx, J.8
Palinski, W.9
Glass, C.K.10
-
10
-
-
0031870652
-
Macrophages in human atheroma contain PPARγ. Differentiation-dependent peroxisomal proliferator-activated γ (PPARγ) expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes in vitro
-
Marx J, Sukhova G, Murphy C, Libby P, Plutzky J. Macrophages in human atheroma contain PPARγ. Differentiation-dependent peroxisomal proliferator-activated γ (PPARγ) expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes in vitro. Am J Pathol. 1998;153:17-23.
-
(1998)
Am J Pathol
, vol.153
, pp. 17-23
-
-
Marx, J.1
Sukhova, G.2
Murphy, C.3
Libby, P.4
Plutzky, J.5
-
11
-
-
0034993832
-
Peroxisome proliferator-activated receptors: From transcriptional control to clinical practice
-
Torra IP, Chinetti G, Duval C, Fruchart J-C, Staels B. Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice. Curr Opin Lipid. 2001;12:245-254.
-
(2001)
Curr Opin Lipid
, vol.12
, pp. 245-254
-
-
Torra, I.P.1
Chinetti, G.2
Duval, C.3
Fruchart, J.-C.4
Staels, B.5
-
12
-
-
0029016829
-
An antidiabetic thiazoldinedione is a high affinity ligand for peroxisome proliferator-activated receptors
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. An antidiabetic thiazoldinedione is a high affinity ligand for peroxisome proliferator-activated receptors. J Biol Chem. 1995;270:12953-12956.
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
13
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors
-
Kliewer SA, Umesono K, Noonan DJ, Heyman RA, Evans RM. Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors. Nature. 1992;358:771-774.
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Heyman, R.A.4
Evans, R.M.5
-
14
-
-
0034678088
-
Peroxisome proliferator-activated receptors: Insight into multiple cellular functions
-
Escher P, Whali W. Peroxisome proliferator-activated receptors: insight into multiple cellular functions. Mutat Res. 2000;448:121-138.
-
(2000)
Mutat Res
, vol.448
, pp. 121-138
-
-
Escher, P.1
Whali, W.2
-
15
-
-
0035139016
-
The role of PPAR-γ in macrophage differentiation and cholesterol uptake
-
Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW. The role of PPAR-γ in macrophage differentiation and cholesterol uptake. Nat Med. 2001;7:41-47.
-
(2001)
Nat Med
, vol.7
, pp. 41-47
-
-
Moore, K.J.1
Rosen, E.D.2
Fitzgerald, M.L.3
Randow, F.4
Andersson, L.P.5
Altshuler, D.6
Milstone, D.S.7
Mortensen, R.M.8
Spiegelman, B.M.9
Freeman, M.W.10
-
16
-
-
0034101821
-
Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice
-
Febbraio M, Podrez EA, Smith JD, Hajjar DP, Hazen SL, Hoff HF, Sharma K, Silverstein RL. Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. J Clin Invest. 2000;105:1049-1056.
-
(2000)
J Clin Invest
, vol.105
, pp. 1049-1056
-
-
Febbraio, M.1
Podrez, E.A.2
Smith, J.D.3
Hajjar, D.P.4
Hazen, S.L.5
Hoff, H.F.6
Sharma, K.7
Silverstein, R.L.8
-
17
-
-
0034123963
-
Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPARγ
-
Feng J, Han J, Pearce SF, Silverstein RL, Gotto AM, Hajjar DP, Nicholson AC. Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPARγ. J Lipid Res. 2000;41:688-696.
-
(2000)
J Lipid Res
, vol.41
, pp. 688-696
-
-
Feng, J.1
Han, J.2
Pearce, S.F.3
Silverstein, R.L.4
Gotto, A.M.5
Hajjar, D.P.6
Nicholson, A.C.7
-
18
-
-
0032540325
-
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
-
Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell. 1998;82:229-240.
-
(1998)
Cell
, vol.82
, pp. 229-240
-
-
Nagy, L.1
Tontonoz, P.2
Alvarez, J.G.3
Chen, H.4
Evans, R.M.5
-
19
-
-
0033864582
-
Peroxisome proliferator-activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
-
Li AC, Brown KK, Silvestre MJ, Willson TM, Palinski W, Glass CK. Peroxisome proliferator-activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice. J Clin Invest. 2000;106:629-631.
-
(2000)
J Clin Invest
, vol.106
, pp. 629-631
-
-
Li, A.C.1
Brown, K.K.2
Silvestre, M.J.3
Willson, T.M.4
Palinski, W.5
Glass, C.K.6
-
20
-
-
0035093258
-
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice
-
Collins AR, Meehan WP, Kintscher U, Jackson S, Wakino S, Noh G, Palinski W, Hsueh WA, Law RE. Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2001;21:365-371.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 365-371
-
-
Collins, A.R.1
Meehan, W.P.2
Kintscher, U.3
Jackson, S.4
Wakino, S.5
Noh, G.6
Palinski, W.7
Hsueh, W.A.8
Law, R.E.9
-
21
-
-
0035097590
-
Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice
-
Chen Z, Ishibashi S, Perrey S, Osuga J, Gotoda T, Kitamine T, Tamura Y, Okazaki G, Yahagi N, Iizuka Y, Shionoiri G, Ohashi K, Harada K, Shimano H, Nagai R, Yamada N. Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice. Arterioscler Thromb Vasc Biol. 2001;21:372-377.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 372-377
-
-
Chen, Z.1
Ishibashi, S.2
Perrey, S.3
Osuga, J.4
Gotoda, T.5
Kitamine, T.6
Tamura, Y.7
Okazaki, G.8
Yahagi, N.9
Iizuka, Y.10
Shionoiri, G.11
Ohashi, K.12
Harada, K.13
Shimano, H.14
Nagai, R.15
Yamada, N.16
-
22
-
-
17744376173
-
A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
-
Chawla A, Boisvert WA, Lee C, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P. A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell. 2001;7:161-171.
-
(2001)
Mol Cell
, vol.7
, pp. 161-171
-
-
Chawla, A.1
Boisvert, W.A.2
Lee, C.3
Laffitte, B.A.4
Barak, Y.5
Joseph, S.B.6
Liao, D.7
Nagy, L.8
Edwards, P.A.9
Curtiss, L.K.10
Evans, R.M.11
Tontonoz, P.12
-
23
-
-
0032540013
-
PPARγ in monocytes: Less pain, any gain?
-
Spiegelman BM. PPARγ in monocytes: less pain, any gain? Cell. 1998;93:153-155.
-
(1998)
Cell
, vol.93
, pp. 153-155
-
-
Spiegelman, B.M.1
-
24
-
-
0035138625
-
Pparα PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
-
Chinetti G, Lestavel S, Bocher V, Remaley AT, Neve B, Torra IP, Teissier E, Minnich A, Jaye M, Duverger N, Brewer HB, Fruchart J-C, Clavey V, Staels B. PPARα and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med. 2001;7:53-58.
-
(2001)
Nat Med
, vol.7
, pp. 53-58
-
-
Chinetti, G.1
Lestavel, S.2
Bocher, V.3
Remaley, A.T.4
Neve, B.5
Torra, I.P.6
Teissier, E.7
Minnich, A.8
Jaye, M.9
Duverger, N.10
Brewer, H.B.11
Fruchart, J.-C.12
Clavey, V.13
Staels, B.14
-
25
-
-
0036205326
-
Conditional disruption of the peroxisome proliferator-activated receptor γ gene in mice results in lowered expression of ABCA1, ABCG1 and apoE in macrophages and reduced cholesterol efflux
-
Akiyama TE, Sakai S, Lambert G, Nicol CJ, Matsusue K, Pimprale S, Lee YH, Ricote M, Glass CK, Brewer HB, Gonzalez FJ. Conditional disruption of the peroxisome proliferator-activated receptor γ gene in mice results in lowered expression of ABCA1, ABCG1 and apoE in macrophages and reduced cholesterol efflux. Mol Cell Biol. 2002;22:2607-2619.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2607-2619
-
-
Akiyama, T.E.1
Sakai, S.2
Lambert, G.3
Nicol, C.J.4
Matsusue, K.5
Pimprale, S.6
Lee, Y.H.7
Ricote, M.8
Glass, C.K.9
Brewer, H.B.10
Gonzalez, F.J.11
-
26
-
-
0033962086
-
Transport of lipids from golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice
-
Orsó E, Broccardo C, Kaminski WE, Böttcher A, Liebisch G, Drobnik W, Götz A, Chambenoit O, Diederich W, Langmann T, Spruss T, Luciani M, Rothe G, Lackner KJ, Chimini G, Schmitz G. Transport of lipids from golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice. Nat Genet. 2000;24:192-196.
-
(2000)
Nat Genet
, vol.24
, pp. 192-196
-
-
Orsó, E.1
Broccardo, C.2
Kaminski, W.E.3
Böttcher, A.4
Liebisch, G.5
Drobnik, W.6
Götz, A.7
Chambenoit, O.8
Diederich, W.9
Langmann, T.10
Spruss, T.11
Luciani, M.12
Rothe, G.13
Lackner, K.J.14
Chimini, G.15
Schmitz, G.16
-
27
-
-
0032725185
-
The tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway
-
Lawn RM, Wade DP, Garvin MR, Wang X, Porter JG, Seilhamer JJ, Vaughan AM, Oram JF. The tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest. 1999;104:R25-R31.
-
(1999)
J Clin Invest
, vol.104
-
-
Lawn, R.M.1
Wade, D.P.2
Garvin, M.R.3
Wang, X.4
Porter, J.G.5
Seilhamer, J.J.6
Vaughan, A.M.7
Oram, J.F.8
-
28
-
-
0031857250
-
Lysosomal sequestration of free and esterified cholesterol from oxidized low density lipoprotein in macrophages of different species
-
Yancey PG, Jerome WG. Lysosomal sequestration of free and esterified cholesterol from oxidized low density lipoprotein in macrophages of different species. J Lipid Res. 1998;39:1349-1361.
-
(1998)
J Lipid Res
, vol.39
, pp. 1349-1361
-
-
Yancey, P.G.1
Jerome, W.G.2
-
29
-
-
1842293994
-
High affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type I/II
-
Lougheed M, Ming Lum, C, Ling W, Suzuki H, Kodama T, Steinbrecher UP. High affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type I/II. J Biol Chem. 1997;272:12938-12944.
-
(1997)
J Biol Chem
, vol.272
, pp. 12938-12944
-
-
Lougheed, M.1
Ming Lum, C.2
Ling, W.3
Suzuki, H.4
Kodama, T.5
Steinbrecher, U.P.6
-
30
-
-
0035571608
-
Transforming growth factor-β1 inhibits macrophage cholesteryl ester accumulation induced by native and oxidized VLDL remnants
-
Argmann CA, Van Den Diepstraten CH, Sawyez CG, Edwards JY, Hegele RA, Wolfe BM, Huff MW. Transforming growth factor-β1 inhibits macrophage cholesteryl ester accumulation induced by native and oxidized VLDL remnants. Arterioscler Thromb Vasc Biol. 2001;21:2011-2018.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 2011-2018
-
-
Argmann, C.A.1
Van Den Diepstraten, C.H.2
Sawyez, C.G.3
Edwards, J.Y.4
Hegele, R.A.5
Wolfe, B.M.6
Huff, M.W.7
-
31
-
-
0034695479
-
A synthetic antagonist for the peroxisome proliferator-activated receptor γ inhibits adipocyte differentiation
-
Wright HM, Clish CB, Mikami T, Hauser S, Yanagi K, Hiramatsu R, Serhan CN, Spiegelman BM. A synthetic antagonist for the peroxisome proliferator-activated receptor γ inhibits adipocyte differentiation. J Biol Chem. 2000;275:1873-1877.
-
(2000)
J Biol Chem
, vol.275
, pp. 1873-1877
-
-
Wright, H.M.1
Clish, C.B.2
Mikami, T.3
Hauser, S.4
Yanagi, K.5
Hiramatsu, R.6
Serhan, C.N.7
Spiegelman, B.M.8
-
32
-
-
0035372651
-
Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: Implications for the development and treatment of atherosclerosis
-
Song C, Hiipakka RA, Liao S. Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: implications for the development and treatment of atherosclerosis. Steroids. 2001;66:473-479.
-
(2001)
Steroids
, vol.66
, pp. 473-479
-
-
Song, C.1
Hiipakka, R.A.2
Liao, S.3
-
33
-
-
0035957006
-
Reduction in atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor
-
Claudel T, Leibowitz MD, Fiévet C, Tailleux A, Wagner B, Repa JJ, Torpier G, Lobaccaro J, Paterniti JR, Mangelsdorf DJ, Heyman RA, Auwerx J. Reduction in atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. Proc Natl Acad Sci U S A. 2001;98:2610-2615.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2610-2615
-
-
Claudel, T.1
Leibowitz, M.D.2
Fiévet, C.3
Tailleux, A.4
Wagner, B.5
Repa, J.J.6
Torpier, G.7
Lobaccaro, J.8
Paterniti, J.R.9
Mangelsdorf, D.J.10
Heyman, R.A.11
Auwerx, J.12
-
34
-
-
0346037268
-
Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages
-
in press
-
Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW. Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages. J Biol Chem 2002: in press.
-
(2002)
J Biol Chem
-
-
Kunjathoor, V.V.1
Febbraio, M.2
Podrez, E.A.3
Moore, K.J.4
Andersson, L.5
Koehn, S.6
Rhee, J.S.7
Silverstein, R.8
Hoff, H.F.9
Freeman, M.W.10
-
35
-
-
0034284918
-
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
-
Repa JJ, Turley SD, Lobaccaro JA, Medina J, Li L, Lustig K, Shan B, Heyman RA, Dietschy JM, Mangelsdorf DJ. Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. Science. 2000;289:1524-1529.
-
(2000)
Science
, vol.289
, pp. 1524-1529
-
-
Repa, J.J.1
Turley, S.D.2
Lobaccaro, J.A.3
Medina, J.4
Li, L.5
Lustig, K.6
Shan, B.7
Heyman, R.A.8
Dietschy, J.M.9
Mangelsdorf, D.J.10
-
36
-
-
0034753508
-
Role of ABCG1 and other ABCG family members in lipid metabolism
-
Schmitz G, Langmann T, Heimerl S. Role of ABCG1 and other ABCG family members in lipid metabolism. J Lipid Res. 2001;42:1513-1520.
-
(2001)
J Lipid Res
, vol.42
, pp. 1513-1520
-
-
Schmitz, G.1
Langmann, T.2
Heimerl, S.3
-
37
-
-
0034623288
-
Sterol-dependent activation of the ABC1 promoter by the liver X receptor/retinoid X receptor
-
Costet P, Luo Y, Wang N, Tall AR. Sterol-dependent activation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J Biol Chem. 2000;275:28240-28245.
-
(2000)
J Biol Chem
, vol.275
, pp. 28240-28245
-
-
Costet, P.1
Luo, Y.2
Wang, N.3
Tall, A.R.4
-
38
-
-
0036852744
-
The macrophage foam cell as a target for therapeutic intervention
-
Li AC, Glass CK. The macrophage foam cell as a target for therapeutic intervention. Nat Med. 2002;8:1235-1242.
-
(2002)
Nat Med
, vol.8
, pp. 1235-1242
-
-
Li, A.C.1
Glass, C.K.2
|