-
1
-
-
3543056130
-
Neurodegeneration and neuroprotection in Parkinson disease
-
Fahn S, Sulzer D, (2004) Neurodegeneration and neuroprotection in Parkinson disease. Neuro Rx 1: 139-154.
-
(2004)
Neuro Rx
, vol.1
, pp. 139-154
-
-
Fahn, S.1
Sulzer, D.2
-
2
-
-
36249026458
-
Dysautonomia and cognitive dysfunction in Parkinson's disease
-
Poewe W, (2007) Dysautonomia and cognitive dysfunction in Parkinson's disease. Mov Disord 22 (Suppl 17): S374-378.
-
(2007)
Mov Disord
, vol.22
, Issue.SUPPL. 17
, pp. 374-378
-
-
Poewe, W.1
-
3
-
-
37649004547
-
Cell systems and the toxic mechanism(s) of alpha-synuclein
-
Cookson MR, van der Brug M, (2008) Cell systems and the toxic mechanism(s) of alpha-synuclein. Exp Neurol 209: 5-11.
-
(2008)
Exp Neurol
, vol.209
, pp. 5-11
-
-
Cookson, M.R.1
van der Brug, M.2
-
4
-
-
5444255434
-
Stages in the development of Parkinson's disease-related pathology
-
Braak H, Ghebremedhin E, Rub U, Bratzke H, Del Tredici K, (2004) Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res 318: 121-134.
-
(2004)
Cell Tissue Res
, vol.318
, pp. 121-134
-
-
Braak, H.1
Ghebremedhin, E.2
Rub, U.3
Bratzke, H.4
Del Tredici, K.5
-
5
-
-
33749240943
-
Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery
-
Lee VM, Trojanowski JQ, (2006) Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery. Neuron 52: 33-38.
-
(2006)
Neuron
, vol.52
, pp. 33-38
-
-
Lee, V.M.1
Trojanowski, J.Q.2
-
6
-
-
20744435383
-
Molecular pathophysiology of Parkinson's disease
-
Moore DJ, West AB, Dawson VL, Dawson TM, (2005) Molecular pathophysiology of Parkinson's disease. Ann Rev Neurosci 28: 57-87.
-
(2005)
Ann Rev Neurosci
, vol.28
, pp. 57-87
-
-
Moore, D.J.1
West, A.B.2
Dawson, V.L.3
Dawson, T.M.4
-
7
-
-
33750594065
-
Genetics of Parkinson's disease and parkinsonism
-
Hardy J, Cai H, Cookson MR, Gwinn-Hardy K, Singleton A, (2006) Genetics of Parkinson's disease and parkinsonism. Ann Neurol 60: 389-398.
-
(2006)
Ann Neurol
, vol.60
, pp. 389-398
-
-
Hardy, J.1
Cai, H.2
Cookson, M.R.3
Gwinn-Hardy, K.4
Singleton, A.5
-
9
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, et al. (1997) Alpha-synuclein in Lewy bodies. Nature 388: 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
-
10
-
-
0035409575
-
Alpha-synuclein and neurodegenerative diseases
-
Goedert M, (2001) Alpha-synuclein and neurodegenerative diseases. Nat Rev Neurosci 2: 492-501.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 492-501
-
-
Goedert, M.1
-
11
-
-
0242300619
-
alpha-Synuclein locus triplication causes Parkinson's disease
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, et al. (2003) alpha-Synuclein locus triplication causes Parkinson's disease. Science 302: 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
-
12
-
-
38349160161
-
The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis
-
Gitler AD, Bevis BJ, Shorter J, Strathearn KE, Hamamichi S, et al. (2008) The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis. Proc Natl Acad Sci U S A 105: 145-150.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 145-150
-
-
Gitler, A.D.1
Bevis, B.J.2
Shorter, J.3
Strathearn, K.E.4
Hamamichi, S.5
-
13
-
-
33746533924
-
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, et al. (2006) Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science 313: 324-328.
-
(2006)
Science
, vol.313
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
Haynes, C.M.4
Hill, K.J.5
-
14
-
-
27544507306
-
Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration
-
Chandra S, Gallardo G, Fernandez-Chacon R, Schluter OM, Sudhof TC, (2005) Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell 123: 383-396.
-
(2005)
Cell
, vol.123
, pp. 383-396
-
-
Chandra, S.1
Gallardo, G.2
Fernandez-Chacon, R.3
Schluter, O.M.4
Sudhof, T.C.5
-
15
-
-
6944227811
-
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
-
Chandra S, Fornai F, Kwon HB, Yazdani U, Atasoy D, et al. (2004) Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions. Proc Natl Acad Sci U S A 101: 14966-14971.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14966-14971
-
-
Chandra, S.1
Fornai, F.2
Kwon, H.B.3
Yazdani, U.4
Atasoy, D.5
-
16
-
-
33751113009
-
{alpha}-Synuclein Overexpression in PC12 and Chromaffin Cells Impairs Catecholamine Release by Interfering with a Late Step in Exocytosis
-
Larsen KE, Schmitz Y, Troyer MD, Mosharov E, Dietrich P, et al. (2006) {alpha}-Synuclein Overexpression in PC12 and Chromaffin Cells Impairs Catecholamine Release by Interfering with a Late Step in Exocytosis. J Neurosci 26: 11915-11922.
-
(2006)
J Neurosci
, vol.26
, pp. 11915-11922
-
-
Larsen, K.E.1
Schmitz, Y.2
Troyer, M.D.3
Mosharov, E.4
Dietrich, P.5
-
17
-
-
58549089901
-
Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling
-
Ben Gedalya T, Loeb V, Israeli E, Altschuler Y, Selkoe DJ, et al. (2009) Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling. Traffic 10: 218-234.
-
(2009)
Traffic
, vol.10
, pp. 218-234
-
-
Ben Gedalya, T.1
Loeb, V.2
Israeli, E.3
Altschuler, Y.4
Selkoe, D.J.5
-
18
-
-
73549085595
-
Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis
-
Nemani VM, Lu W, Berge V, Nakamura K, Onoa B, et al. (2010) Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron 65: 66-79.
-
(2010)
Neuron
, vol.65
, pp. 66-79
-
-
Nemani, V.M.1
Lu, W.2
Berge, V.3
Nakamura, K.4
Onoa, B.5
-
19
-
-
0034193399
-
Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
-
Murphy DD, Rueter SM, Trojanowski JQ, Lee VM, (2000) Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J Neurosci 20: 3214-3220.
-
(2000)
J Neurosci
, vol.20
, pp. 3214-3220
-
-
Murphy, D.D.1
Rueter, S.M.2
Trojanowski, J.Q.3
Lee, V.M.4
-
20
-
-
0037109727
-
Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein
-
Cabin DE, Shimazu K, Murphy D, Cole NB, Gottschalk W, et al. (2002) Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein. J Neurosci 22: 8797-8807.
-
(2002)
J Neurosci
, vol.22
, pp. 8797-8807
-
-
Cabin, D.E.1
Shimazu, K.2
Murphy, D.3
Cole, N.B.4
Gottschalk, W.5
-
21
-
-
85109083933
-
Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma
-
El-Agnaf OM, Salem SA, Paleologou KE, Cooper LJ, Fullwood NJ, et al. (2003) Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma. Faseb J 17: 1945-1947.
-
(2003)
Faseb J
, vol.17
, pp. 1945-1947
-
-
El-Agnaf, O.M.1
Salem, S.A.2
Paleologou, K.E.3
Cooper, L.J.4
Fullwood, N.J.5
-
22
-
-
37849028683
-
Red blood cells are the major source of alpha-synuclein in blood
-
Barbour R, Kling K, Anderson JP, Banducci K, Cole T, et al. (2008) Red blood cells are the major source of alpha-synuclein in blood. Neurodegener Dis 5: 55-59.
-
(2008)
Neurodegener Dis
, vol.5
, pp. 55-59
-
-
Barbour, R.1
Kling, K.2
Anderson, J.P.3
Banducci, K.4
Cole, T.5
-
23
-
-
47349127878
-
Parkinson patient fibroblasts show increased alpha-synuclein expression
-
Hoepken HH, Gispert S, Azizov M, Klinkenberg M, Ricciardi F, et al. (2008) Parkinson patient fibroblasts show increased alpha-synuclein expression. Exp Neurol 212: 307-313.
-
(2008)
Exp Neurol
, vol.212
, pp. 307-313
-
-
Hoepken, H.H.1
Gispert, S.2
Azizov, M.3
Klinkenberg, M.4
Ricciardi, F.5
-
24
-
-
0033980068
-
alpha-Synuclein is expressed in a variety of brain tumors showing neuronal differentiation
-
Kawashima M, Suzuki SO, Doh-ura K, Iwaki T, (2000) alpha-Synuclein is expressed in a variety of brain tumors showing neuronal differentiation. Acta Neuropathol 99: 154-160.
-
(2000)
Acta Neuropathol
, vol.99
, pp. 154-160
-
-
Kawashima, M.1
Suzuki, S.O.2
Doh-ura, K.3
Iwaki, T.4
-
25
-
-
0037592405
-
Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas
-
Fung KM, Rorke LB, Giasson B, Lee VM, Trojanowski JQ, (2003) Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas. Acta Neuropathol (Berl) 106: 167-175.
-
(2003)
Acta Neuropathol (Berl)
, vol.106
, pp. 167-175
-
-
Fung, K.M.1
Rorke, L.B.2
Giasson, B.3
Lee, V.M.4
Trojanowski, J.Q.5
-
26
-
-
0034193239
-
Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary
-
Bruening W, Giasson BI, Klein-Szanto AJ, Lee VM, Trojanowski JQ, et al. (2000) Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary. Cancer 88: 2154-2163.
-
(2000)
Cancer
, vol.88
, pp. 2154-2163
-
-
Bruening, W.1
Giasson, B.I.2
Klein-Szanto, A.J.3
Lee, V.M.4
Trojanowski, J.Q.5
-
27
-
-
76649098026
-
Expression of alpha-, beta- and gamma-synuclein in colorectal cancer, and potential clinical significance in progression of the disease
-
Ye Q, Wang TF, Peng YF, Xie J, Feng B, et al. (2010) Expression of alpha-, beta- and gamma-synuclein in colorectal cancer, and potential clinical significance in progression of the disease. Oncol Rep 23: 429-436.
-
(2010)
Oncol Rep
, vol.23
, pp. 429-436
-
-
Ye, Q.1
Wang, T.F.2
Peng, Y.F.3
Xie, J.4
Feng, B.5
-
28
-
-
77956276535
-
Parkinson's disease-related protein, alpha-synuclein, in malignant melanoma
-
Matsuo Y, Kamitani T, (2010) Parkinson's disease-related protein, alpha-synuclein, in malignant melanoma. PLoS One 5: e10481.
-
(2010)
PLoS One
, vol.5
-
-
Matsuo, Y.1
Kamitani, T.2
-
29
-
-
48949100108
-
Tumorigenesis and neurodegeneration: two sides of the same coin?
-
Staropoli JF, (2008) Tumorigenesis and neurodegeneration: two sides of the same coin? Bioessays 30: 719-727.
-
(2008)
Bioessays
, vol.30
, pp. 719-727
-
-
Staropoli, J.F.1
-
30
-
-
77953801296
-
Genetic determinants at the interface of cancer and neurodegenerative disease
-
Morris LG, Veeriah S, Chan TA, (2010) Genetic determinants at the interface of cancer and neurodegenerative disease. Oncogene 29: 3453-3464.
-
(2010)
Oncogene
, vol.29
, pp. 3453-3464
-
-
Morris, L.G.1
Veeriah, S.2
Chan, T.A.3
-
31
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, et al. (2002) Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 34: 521-533.
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
-
32
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase
-
Jankowsky JL, Fadale DJ, Anderson J, Xu GM, Gonzales V, et al. (2004) Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Hum Mol Genet 13: 159-170.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
-
33
-
-
0035789203
-
Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
-
Specht CG, Schoepfer R, (2001) Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice. BMC Neurosci 2: 11.
-
(2001)
BMC Neurosci
, vol.2
, pp. 11
-
-
Specht, C.G.1
Schoepfer, R.2
-
34
-
-
0344305380
-
Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease
-
Jankowsky JL, Xu G, Fromholt D, Gonzales V, Borchelt DR, (2003) Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease. J Neuropathol Exp Neurol 62: 1220-1227.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 1220-1227
-
-
Jankowsky, J.L.1
Xu, G.2
Fromholt, D.3
Gonzales, V.4
Borchelt, D.R.5
-
35
-
-
68949173796
-
IL2-caspase3 chimeric protein controls lymphocyte reactivity by targeted apoptosis, leading to amelioration of experimental autoimmune encephalomyelitis
-
Irony-Tur-Sinai M, Lichtenstein M, Brenner T, Lorberboum-Galski H, (2009) IL2-caspase3 chimeric protein controls lymphocyte reactivity by targeted apoptosis, leading to amelioration of experimental autoimmune encephalomyelitis. Int Immunopharmacol 9: 1236-1243.
-
(2009)
Int Immunopharmacol
, vol.9
, pp. 1236-1243
-
-
Irony-Tur-Sinai, M.1
Lichtenstein, M.2
Brenner, T.3
Lorberboum-Galski, H.4
-
36
-
-
0020592691
-
MHC imbalance and metastatic spread in Lewis lung carcinoma clones
-
Eisenbach L, Segal S, Feldman M, (1983) MHC imbalance and metastatic spread in Lewis lung carcinoma clones. Int J Cancer 32: 113-120.
-
(1983)
Int J Cancer
, vol.32
, pp. 113-120
-
-
Eisenbach, L.1
Segal, S.2
Feldman, M.3
-
37
-
-
38349006201
-
Polyunsaturated Fatty Acids Induce {alpha}-Synuclein-Related Pathogenic Changes in Neuronal Cells
-
Assayag K, Yakunin E, Loeb V, Selkoe DJ, Sharon R, (2007) Polyunsaturated Fatty Acids Induce {alpha}-Synuclein-Related Pathogenic Changes in Neuronal Cells. Am J Pathol 171: 2000-2011.
-
(2007)
Am J Pathol
, vol.171
, pp. 2000-2011
-
-
Assayag, K.1
Yakunin, E.2
Loeb, V.3
Selkoe, D.J.4
Sharon, R.5
-
38
-
-
57549098245
-
Beta-synuclein occurs in vivo in lipid-associated oligomers and forms hetero-oligomers with alpha-synuclein
-
Israeli E, Sharon R, (2009) Beta-synuclein occurs in vivo in lipid-associated oligomers and forms hetero-oligomers with alpha-synuclein. J Neurochem 108: 465-474.
-
(2009)
J Neurochem
, vol.108
, pp. 465-474
-
-
Israeli, E.1
Sharon, R.2
-
39
-
-
0028866435
-
The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway
-
Haass C, Lemere CA, Capell A, Citron M, Seubert P, et al. (1995) The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway. Nat Med 1: 1291-1296.
-
(1995)
Nat Med
, vol.1
, pp. 1291-1296
-
-
Haass, C.1
Lemere, C.A.2
Capell, A.3
Citron, M.4
Seubert, P.5
-
40
-
-
77951239770
-
The transgenic over expression of {alpha}-Synuclein and not its related pathology, associates with complex I inhibition
-
Loeb V, Yakunin E, Saada A, Sharon R, (2010) The transgenic over expression of {alpha}-Synuclein and not its related pathology, associates with complex I inhibition. J Biol Chem 285: 7334-7343.
-
(2010)
J Biol Chem
, vol.285
, pp. 7334-7343
-
-
Loeb, V.1
Yakunin, E.2
Saada, A.3
Sharon, R.4
-
41
-
-
0017065896
-
Release of tumor-associated antigens by murine melanoma cells
-
Bystryn JC, (1976) Release of tumor-associated antigens by murine melanoma cells. J Immunol 116: 1302-1305.
-
(1976)
J Immunol
, vol.116
, pp. 1302-1305
-
-
Bystryn, J.C.1
-
42
-
-
0028874995
-
A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep
-
Horiuchi M, Yamazaki N, Ikeda T, Ishiguro N, Shinagawa M, (1995) A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep. J Gen Virol 76 (Pt 10): 2583-2587.
-
(1995)
J Gen Virol
, vol.76
, Issue.Pt 10
, pp. 2583-2587
-
-
Horiuchi, M.1
Yamazaki, N.2
Ikeda, T.3
Ishiguro, N.4
Shinagawa, M.5
-
43
-
-
21344456506
-
Intravesicular localization and exocytosis of alpha-synuclein and its aggregates
-
Lee HJ, Patel S, Lee SJ, (2005) Intravesicular localization and exocytosis of alpha-synuclein and its aggregates. J Neurosci 25: 6016-6024.
-
(2005)
J Neurosci
, vol.25
, pp. 6016-6024
-
-
Lee, H.J.1
Patel, S.2
Lee, S.J.3
-
44
-
-
33748932543
-
The plasma alpha-synuclein levels in patients with Parkinson's disease and multiple system atrophy
-
Lee PH, Lee G, Park HJ, Bang OY, Joo IS, et al. (2006) The plasma alpha-synuclein levels in patients with Parkinson's disease and multiple system atrophy. J Neural Transm 113: 1435-1439.
-
(2006)
J Neural Transm
, vol.113
, pp. 1435-1439
-
-
Lee, P.H.1
Lee, G.2
Park, H.J.3
Bang, O.Y.4
Joo, I.S.5
-
45
-
-
0034674376
-
Full length alpha-synuclein is present in cerebrospinal fluid from Parkinson's disease and normal subjects
-
Borghi R, Marchese R, Negro A, Marinelli L, Forloni G, et al. (2000) Full length alpha-synuclein is present in cerebrospinal fluid from Parkinson's disease and normal subjects. Neurosci Lett 287: 65-67.
-
(2000)
Neurosci Lett
, vol.287
, pp. 65-67
-
-
Borghi, R.1
Marchese, R.2
Negro, A.3
Marinelli, L.4
Forloni, G.5
-
46
-
-
78649990079
-
Detection of elevated levels of alpha-synuclein oligomers in CSF from patients with Parkinson disease
-
Tokuda T, Qureshi MM, Ardah MT, Varghese S, Shehab SA, et al. (2011) Detection of elevated levels of alpha-synuclein oligomers in CSF from patients with Parkinson disease. Neurology 75: 1766-1772.
-
(2011)
Neurology
, vol.75
, pp. 1766-1772
-
-
Tokuda, T.1
Qureshi, M.M.2
Ardah, M.T.3
Varghese, S.4
Shehab, S.A.5
-
47
-
-
35148865254
-
Are Parkinson disease patients protected from some but not all cancers?
-
Inzelberg R, J. J, (2007) Are Parkinson disease patients protected from some but not all cancers? neurology 69: 1542-1550.
-
(2007)
Neurology
, vol.69
, pp. 1542-1550
-
-
Inzelberg, R.1
J, J.2
-
48
-
-
61649091807
-
Parkinson's disease and cancer: insights for pathogenesis from epidemiology
-
D'Amelio M, Ragonese P, Sconzo G, Aridon P, Savettieri G, (2009) Parkinson's disease and cancer: insights for pathogenesis from epidemiology. Ann N Y Acad Sci 1155: 324-334.
-
(2009)
Ann N Y Acad Sci
, vol.1155
, pp. 324-334
-
-
D'Amelio, M.1
Ragonese, P.2
Sconzo, G.3
Aridon, P.4
Savettieri, G.5
-
49
-
-
77955293560
-
Parkinson's disease and cancer risk: a systematic review and meta-analysis
-
Bajaj A, Driver JA, Schernhammer ES, (2010) Parkinson's disease and cancer risk: a systematic review and meta-analysis. Cancer Causes Control 21: 697-707.
-
(2010)
Cancer Causes Control
, vol.21
, pp. 697-707
-
-
Bajaj, A.1
Driver, J.A.2
Schernhammer, E.S.3
-
51
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, et al. (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276: 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
-
52
-
-
0035871660
-
DNA replication precedes neuronal cell death in Alzheimer's disease
-
Yang Y, Geldmacher DS, Herrup K, (2001) DNA replication precedes neuronal cell death in Alzheimer's disease. J Neurosci 21: 2661-2668.
-
(2001)
J Neurosci
, vol.21
, pp. 2661-2668
-
-
Yang, Y.1
Geldmacher, D.S.2
Herrup, K.3
-
53
-
-
58349085737
-
What causes cell death in Parkinson's disease?
-
Gupta A, Dawson VL, Dawson TM, (2008) What causes cell death in Parkinson's disease? Ann Neurol 64 (Suppl 2): S3-15.
-
(2008)
Ann Neurol
, vol.64
, Issue.SUPPL. 2
-
-
Gupta, A.1
Dawson, V.L.2
Dawson, T.M.3
-
54
-
-
77950360574
-
Parkinson's disease and cancer: the unexplored connection
-
Garber K, (2010) Parkinson's disease and cancer: the unexplored connection. J Natl Cancer Inst 102: 371-374.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 371-374
-
-
Garber, K.1
-
55
-
-
77953424577
-
The role of parkin in familial and sporadic Parkinson's disease
-
Dawson TM, Dawson VL, (2010) The role of parkin in familial and sporadic Parkinson's disease. Mov Disord 25 (Suppl 1): S32-39.
-
(2010)
Mov Disord
, vol.25
, Issue.SUPPL. 1
, pp. 32-39
-
-
Dawson, T.M.1
Dawson, V.L.2
-
56
-
-
73349125417
-
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies
-
Veeriah S, Taylor BS, Meng S, Fang F, Yilmaz E, et al. (2010) Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies. Nat Genet 42: 77-82.
-
(2010)
Nat Genet
, vol.42
, pp. 77-82
-
-
Veeriah, S.1
Taylor, B.S.2
Meng, S.3
Fang, F.4
Yilmaz, E.5
-
57
-
-
77950360574
-
Parkinson's disease and cancer: the unexplored connection
-
Garber K, Parkinson's disease and cancer: the unexplored connection. J Natl Cancer Inst 102: 371-374.
-
J Natl Cancer Inst
, vol.102
, pp. 371-374
-
-
Garber, K.1
-
58
-
-
77956990244
-
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice
-
Poulogiannis G, McIntyre RE, Dimitriadi M, Apps JR, Wilson CH, et al. (2010) PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice. Proc Natl Acad Sci U S A.
-
(2010)
Proc Natl Acad Sci U S A
-
-
Poulogiannis, G.1
McIntyre, R.E.2
Dimitriadi, M.3
Apps, J.R.4
Wilson, C.H.5
-
59
-
-
77956517757
-
Parkin enhances the expression of cyclin-dependent kinase 6 and negatively regulates the proliferation of breast cancer cells
-
Tay SP, Yeo CW, Chai C, Chua PJ, Tan HM, et al. (2010) Parkin enhances the expression of cyclin-dependent kinase 6 and negatively regulates the proliferation of breast cancer cells. J Biol Chem.
-
(2010)
J Biol Chem
-
-
Tay, S.P.1
Yeo, C.W.2
Chai, C.3
Chua, P.J.4
Tan, H.M.5
-
60
-
-
0037422010
-
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
-
Staropoli JF, McDermott C, Martinat C, Schulman B, Demireva E, et al. (2003) Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron 37: 735-749.
-
(2003)
Neuron
, vol.37
, pp. 735-749
-
-
Staropoli, J.F.1
McDermott, C.2
Martinat, C.3
Schulman, B.4
Demireva, E.5
-
61
-
-
33749246152
-
Beta-synuclein modulates alpha-synuclein neurotoxicity by reducing alpha-synuclein protein expression
-
Fan Y, Limprasert P, Murray IV, Smith AC, Lee VM, et al. (2006) Beta-synuclein modulates alpha-synuclein neurotoxicity by reducing alpha-synuclein protein expression. Hum Mol Genet 15: 3002-3011.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 3002-3011
-
-
Fan, Y.1
Limprasert, P.2
Murray, I.V.3
Smith, A.C.4
Lee, V.M.5
-
62
-
-
4644359042
-
Beta-synuclein gene alterations in dementia with Lewy bodies
-
Ohtake H, Limprasert P, Fan Y, Onodera O, Kakita A, et al. (2004) Beta-synuclein gene alterations in dementia with Lewy bodies. Neurology 63: 805-811.
-
(2004)
Neurology
, vol.63
, pp. 805-811
-
-
Ohtake, H.1
Limprasert, P.2
Fan, Y.3
Onodera, O.4
Kakita, A.5
-
63
-
-
78650066331
-
A beta-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain
-
Fujita M, Sugama S, Sekiyama K, Sekigawa A, Tsukui T, et al. (2010) A beta-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain. Nat Commun 1: 110.
-
(2010)
Nat Commun
, vol.1
, pp. 110
-
-
Fujita, M.1
Sugama, S.2
Sekiyama, K.3
Sekigawa, A.4
Tsukui, T.5
-
64
-
-
35948969417
-
Gamma-synuclein and the progression of cancer
-
Ahmad M, Attoub S, Singh MN, Martin FL, El-Agnaf OM, (2007) Gamma-synuclein and the progression of cancer. Faseb J 21: 3419-3430.
-
(2007)
Faseb J
, vol.21
, pp. 3419-3430
-
-
Ahmad, M.1
Attoub, S.2
Singh, M.N.3
Martin, F.L.4
El-Agnaf, O.M.5
-
65
-
-
0031045589
-
Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing
-
Ji H, Liu YE, Jia T, Wang M, Liu J, et al. (1997) Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing. Cancer Res 57: 759-764.
-
(1997)
Cancer Res
, vol.57
, pp. 759-764
-
-
Ji, H.1
Liu, Y.E.2
Jia, T.3
Wang, M.4
Liu, J.5
-
66
-
-
67549114830
-
Synuclein-gamma (SNCG) may be a novel prognostic biomarker in uterine papillary serous carcinoma
-
Morgan J, Hoekstra AV, Chapman-Davis E, Hardt JL, Kim JJ, et al. (2009) Synuclein-gamma (SNCG) may be a novel prognostic biomarker in uterine papillary serous carcinoma. Gynecol Oncol 114: 293-298.
-
(2009)
Gynecol Oncol
, vol.114
, pp. 293-298
-
-
Morgan, J.1
Hoekstra, A.V.2
Chapman-Davis, E.3
Hardt, J.L.4
Kim, J.J.5
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