-
1
-
-
68849120728
-
Challenges in the management of epilepsy in resource-poor countries
-
Radhakrishnan K. Challenges in the management of epilepsy in resource-poor countries. Nat Rev Neurol 2009;5:323-30.
-
(2009)
Nat Rev Neurol
, vol.5
, pp. 323-330
-
-
Radhakrishnan, K.1
-
2
-
-
0032891143
-
Prevalence and pattern of epilepsy in India
-
Sridharan R, Murthy BN. Prevalence and pattern of epilepsy in India. Epilepsia 1999;40:631-6. (Pubitemid 29207328)
-
(1999)
Epilepsia
, vol.40
, Issue.5
, pp. 631-636
-
-
Sridharan, R.1
Murthy, B.N.2
-
3
-
-
0033883885
-
Prevalence, knowledge, attitude and practice of epilepsy in Kerala, South India
-
Radhakrishnan K, Pandian JD, Santhoshkumar T, Thomas SV, Deetha TD, Sarma PS, et al. Prevalence, knowledge, attitude, and practice of epilepsy in Kerala, South India. Epilepsia 2000;41:1027-35. (Pubitemid 30640869)
-
(2000)
Epilepsia
, vol.41
, Issue.8
, pp. 1027-1035
-
-
Radhakrishnan, K.1
Pandian, J.D.2
Santhoshkumar, T.3
Thomas, S.V.4
Deetha, T.D.5
Sarma, P.S.6
Jayachandran, D.7
Mohamed, E.8
-
4
-
-
0034598762
-
Early identification of refractory epilepsy
-
DOI 10.1056/NEJM200002033420503
-
Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med 2000;342:314-9. (Pubitemid 30075244)
-
(2000)
New England Journal of Medicine
, vol.342
, Issue.5
, pp. 314-319
-
-
Kwan, P.1
Brodie, M.J.2
-
5
-
-
33847117296
-
Refractory epilepsy: Clinical overview
-
DOI 10.1111/j.1528-1167.2007.00992.x
-
French JA. Refractory epilepsy: Clinical overview. Epilepsia 2007;48:3-7. (Pubitemid 46280512)
-
(2007)
Epilepsia
, vol.48
, Issue.SUPPL. 1
, pp. 3-7
-
-
French, J.A.1
-
6
-
-
0033586952
-
Patients with refractory seizures
-
DOI 10.1056/NEJM199905203402008
-
Devinsky O. Patients with refractory seizures. N Engl J Med 1999;340:1565-70. (Pubitemid 29228187)
-
(1999)
New England Journal of Medicine
, vol.340
, Issue.20
, pp. 1565-1570
-
-
Devinsky, O.1
-
7
-
-
1642460797
-
The consequences of uncontrolled epilepsy
-
106-9
-
Sperling MR. The consequences of uncontrolled epilepsy. CNS Spectr 2004;9:98-101, 106-9.
-
(2004)
CNS Spectr
, vol.9
, pp. 98-101
-
-
Sperling, M.R.1
-
8
-
-
20544475805
-
Drug resistance in epilepsy: Putative neurobiologic and clinical mechanisms
-
DOI 10.1111/j.1528-1167.2005.54904.x
-
Schmidt D, Löscher W. Drug resistance in epilepsy: Putative neurobiologic and clinical mechanisms. Epilepsia 2005;46:858-77. (Pubitemid 40847354)
-
(2005)
Epilepsia
, vol.46
, Issue.6
, pp. 858-877
-
-
Schmidt, D.1
Loscher, W.2
-
9
-
-
30344467212
-
Molecular and cellular mechanisms of pharmacoresistance in epilepsy
-
DOI 10.1093/brain/awh682
-
Remy S, Beck H. Molecular and cellular mechanisms of pharmacoresistance in epilepsy. Brain 2006;129:18-35. (Pubitemid 43063756)
-
(2006)
Brain
, vol.129
, Issue.1
, pp. 18-35
-
-
Remy, S.1
Beck, H.2
-
10
-
-
0036499726
-
Current status and future directions in the pharmacotherapy of epilepsy
-
DOI 10.1016/S0165-6147(00)01974-X, PII S016561470001974X
-
Löscher W. Current status and future directions in the pharmacotherapy of epilepsy. Trends Pharmacol Sci 2002;23:113-8. (Pubitemid 34185411)
-
(2002)
Trends in Pharmacological Sciences
, vol.23
, Issue.3
, pp. 113-118
-
-
Loscher, W.1
-
11
-
-
23044500398
-
Drug resistance in brain diseases and the role of drug efflux transporters
-
DOI 10.1038/nrn1728
-
Löscher W, Potschka H. Drug resistance in brain diseases and the role of drug efflux transporters. Nat Rev Neurosci 2005;6:591-602. (Pubitemid 41059334)
-
(2005)
Nature Reviews Neuroscience
, vol.6
, Issue.8
, pp. 591-602
-
-
Loscher, W.1
Potschka, H.2
-
12
-
-
33847125762
-
Plasticity of antiepileptic drug targets
-
DOI 10.1111/j.1528-1167.2007.00994.x
-
Beck H. Plasticity of antiepileptic drug targets. Epilepsia 2007;48:14-8. (Pubitemid 46280514)
-
(2007)
Epilepsia
, vol.48
, Issue.SUPPL. 1
, pp. 14-18
-
-
Beck, H.1
-
13
-
-
63449139456
-
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
-
Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, et al. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science 2009;323:1718-22.
-
(2009)
Science
, vol.323
, pp. 1718-1722
-
-
Aller, S.G.1
Yu, J.2
Ward, A.3
Weng, Y.4
Chittaboina, S.5
Zhuo, R.6
-
14
-
-
58149231251
-
The clinical impact of pharmacogenetics on the treatment of epilepsy
-
Löscher W, Klotz U, Zimprich F, Schmidt D. The clinical impact of pharmacogenetics on the treatment of epilepsy. Epilepsia 2009;50:1-23.
-
(2009)
Epilepsia
, vol.50
, pp. 1-23
-
-
Löscher, W.1
Klotz, U.2
Zimprich, F.3
Schmidt, D.4
-
15
-
-
0037399407
-
Mechanisms of antiepileptic drug resistance
-
DOI 10.1097/00019052-200304000-00013
-
Sisodiya SM. Mechanisms of antiepileptic drug resistance. Curr Opin Neurol 2003;16:197-201. (Pubitemid 36521207)
-
(2003)
Current Opinion in Neurology
, vol.16
, Issue.2
, pp. 197-201
-
-
Sisodiya, S.M.1
-
16
-
-
0037101618
-
Limbic seizures induce P-glycoprotein in rodent brain: Functional implications for pharmacoresistance
-
Rizzi M, Caccia S, Guiso G, Richichi C, Gorter JA, Aronica E, et al. Limbic seizures induce P-glycoprotein in rodent brain: Functional implications for pharmacoresistance. J Neurosci 2002;22:5833-9.
-
(2002)
J Neurosci
, vol.22
, pp. 5833-9
-
-
Rizzi, M.1
Caccia, S.2
Guiso, G.3
Richichi, C.4
Gorter, J.A.5
Aronica, E.6
-
17
-
-
34250761890
-
Region-specific overexpression of P-glycoprotein at the blood-brain barrier affects brain uptake of phenytoin in epileptic rats
-
DOI 10.1124/jpet.107.121178
-
Van Vliet EA, van Schaik R, Edelbroek PM, Voskuyl RA, Redeker S, Aronica E, et al. Region-specific overexpression of P-glycoprotein at the blood-brain barrier affects brain uptake of phenytoin in epileptic rats. J Pharmacol Exp Ther 2007;322:141-7. (Pubitemid 46956371)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.322
, Issue.1
, pp. 141-147
-
-
Van Vliet, E.A.1
Van Schaik, R.2
Edelbroek, P.M.3
Voskuyl, R.A.4
Redeker, S.5
Aronica, E.6
Wadman, W.J.7
Gorter, J.A.8
-
18
-
-
27244446035
-
A pilot study on brain-to plasma partition of 10,11-dyhydro-10-hydroxy- 5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine
-
Marchi N, Guiso G, Rizzi M, Pirker S, Novak K, Czech T, et al. A pilot study on brain-to plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f) azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine. Epilepsia 2005;46:1613-9.
-
(2005)
Epilepsia
, vol.46
, pp. 1613-9
-
-
Marchi, N.1
Guiso, G.2
Rizzi, M.3
Pirker, S.4
Novak, K.5
Czech, T.6
-
19
-
-
0028895740
-
MDR1 gene expression in brain of patients with medically intractable epilepsy
-
Tishler DM, Weinberg KI, Hinton DR, Barbaro N, Annett GM, Raffel C. MDR1 gene expression in brain of patients with medically intractable epilepsy. Epilepsia 1995;36:1-6.
-
(1995)
Epilepsia
, vol.36
, pp. 1-6
-
-
Tishler, D.M.1
Weinberg, K.I.2
Hinton, D.R.3
Barbaro, N.4
Annett, G.M.5
Raffel, C.6
-
20
-
-
0036156280
-
Drug resistance in epilepsy: Expression of drug resistance proteins in common causes of refractory epilepsy
-
Sisodiya SM, Lin WR, Harding BN, Squier MV, Thom M. Drug resistance in epilepsy: Expression of drug resistance proteins in common causes of refractory epilepsy. Brain 2002;125:22-31. (Pubitemid 34084034)
-
(2002)
Brain
, vol.125
, Issue.1
, pp. 22-31
-
-
Sisodiya, S.M.1
Lin, W.-R.2
Harding, B.N.3
Squier, M.V.4
Thom, M.5
-
21
-
-
33847625066
-
Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs
-
DOI 10.1111/j.1528-1167.2006.00960.x
-
Cucullo L, Hossain M, Rapp E, Manders T, Marchi N, Janigro D. Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs. Epilepsia 2007;48:505-16. (Pubitemid 46365189)
-
(2007)
Epilepsia
, vol.48
, Issue.3
, pp. 505-516
-
-
Cucullo, L.1
Hossain, M.2
Rapp, E.3
Manders, T.4
Marchi, N.5
Janigro, D.6
-
22
-
-
33748792802
-
The multidrug transporter hypothesis of drug resistance in epilepsy: Proof-of-principle in a rat model of temporal lobe epilepsy
-
DOI 10.1016/j.nbd.2006.06.014, PII S0969996106001513
-
Brandt C, Bethmann K, Gastens AM, Löscher W. The multidrug transporter hypothesis of drug resistance in epilepsy: Proof-of-principle in a rat model of temporal lobe epilepsy. Neurobiol Dis 2006;24:202-11. (Pubitemid 44416217)
-
(2006)
Neurobiology of Disease
, vol.24
, Issue.1
, pp. 202-211
-
-
Brandt, C.1
Bethmann, K.2
Gastens, A.M.3
Loscher, W.4
-
23
-
-
33645513798
-
Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats
-
van Vliet EA, van Schaik R, Edelbroek PM, Redeker S, Aronica E, Wadman WJ, et al. Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats. Epilepsia 2006;47:672-80.
-
(2006)
Epilepsia
, vol.47
, pp. 672-680
-
-
Van Vliet, E.A.1
Van Schaik, R.2
Edelbroek, P.M.3
Redeker, S.4
Aronica, E.5
Wadman, W.J.6
-
24
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P- glycoprotein expression and activity in vivo
-
DOI 10.1073/pnas.050585397
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmoller J, Johne A, et al. In vivo Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity. Proc Natl Acad Sci USA 2000;97:3473-8. (Pubitemid 30183327)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
Brinkmann, U.11
-
25
-
-
1642523162
-
Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
-
DOI 10.1016/j.clpt.2003.09.012
-
Marzolini C, Paus E, Buclin T, Kim RB. Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance. Clin Pharmacol Ther 2004;75:13-33. (Pubitemid 38130115)
-
(2004)
Clinical Pharmacology and Therapeutics
, vol.75
, Issue.1
, pp. 13-33
-
-
Marzolini, C.1
Paus, E.2
Buclin, T.3
Kim, R.B.4
-
26
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
DOI 10.1126/science.1135308
-
Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, et al. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 2007;315:525-8. (Pubitemid 46175758)
-
(2007)
Science
, vol.315
, Issue.5811
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.-W.3
Sauna, Z.E.4
Calcagno, A.M.5
Ambudkar, S.V.6
Gottesman, M.M.7
-
27
-
-
69949133732
-
Analysis of genotype and haplotype effects of ABCB1 (MDR1) polymorphisms in the risk of medically refractory epilepsy in an Indian population
-
Vahab SA, Sen S, Ravindran N, Mony S, Mathew A, Vijayan N, et al. Analysis of genotype and haplotype effects of ABCB1 (MDR1) polymorphisms in the risk of medically refractory epilepsy in an Indian population. Drug Metab Pharmacokinet 2009;24:255-60.
-
(2009)
Drug Metab Pharmacokinet
, vol.24
, pp. 255-260
-
-
Vahab, S.A.1
Sen, S.2
Ravindran, N.3
Mony, S.4
Mathew, A.5
Vijayan, N.6
-
28
-
-
0037431040
-
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1
-
DOI 10.1056/NEJMoa021986
-
Siddiqui A, Kerb R, Weale ME, Brinkmann U, Smith A, Goldstein DB, et al. Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. N Engl J Med 2003;348:1442-8. (Pubitemid 36407173)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.15
, pp. 1442-1448
-
-
Siddiqui, A.1
Kerb, R.2
Weale, M.E.3
Brinkmann, U.4
Smith, A.5
Goldstein, D.B.6
Wood, N.W.7
Sisodiya, S.M.8
-
29
-
-
3543149022
-
Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene
-
DOI 10.1101/gr.1965304
-
Soranzo N, Cavalleri GL, Weale ME, Wood NW, Depondt C, Marguerie R, et al. Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene. Genome Res 2004;14:1333-44. (Pubitemid 39029230)
-
(2004)
Genome Research
, vol.14
, Issue.7
, pp. 1333-1344
-
-
Soranzo, N.1
Cavalleri, G.L.2
Weale, M.E.3
Wood, N.W.4
Depondt, C.5
Marguerie, R.6
Sisodiya, S.M.7
Goldstein, D.B.8
-
30
-
-
4644305242
-
Association of an ABCB1 gene haplotype with pharmacoresistance in temporal lobe epilepsy
-
Zimprich F, Sunder-Plassmann R, Stogmann E, Gleiss A, Dal Bianco A, Zimprich A, et al. Association of an ABCB1 gene haplotype with pharmacoresistance in temporal lobe epilepsy. Neurology 2004;63:1087-9. (Pubitemid 39287922)
-
(2004)
Neurology
, vol.63
, Issue.6
, pp. 1087-1089
-
-
Zimprich, F.1
Sunder-Plassmann, R.2
Stogmann, E.3
Gleiss, A.4
Dal-Bianco, A.5
Zimprich, A.6
Plumer, S.7
Baumgartner, C.8
Mannhalter, C.9
-
31
-
-
21444449353
-
Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response
-
DOI 10.1517/14622416.6.4.411
-
Hung CC, Tai JJ, Lin CJ, Lee MJ, Liou HH. Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response. Pharmacogenomics 2005;6:411-7. (Pubitemid 40916364)
-
(2005)
Pharmacogenomics
, vol.6
, Issue.4
, pp. 411-417
-
-
Hung, C.-C.1
Tai, J.J.2
Lin, C.-J.3
Lee, M.-J.4
Liou, H.-H.5
-
32
-
-
33745155394
-
ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients
-
DOI 10.2217/14622416.7.4.551
-
Seo T, Ishitsu T, Ueda N, Nakada N, Yurube K, Ueda K, et al. ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients. Pharmacogenomics 2006;7:551-61. (Pubitemid 43891412)
-
(2006)
Pharmacogenomics
, vol.7
, Issue.4
, pp. 551-561
-
-
Seo, T.1
Ishitsu, T.2
Ueda, N.3
Nakada, N.4
Yurube, K.5
Ueda, K.6
Nakagawa, K.7
-
33
-
-
34447619872
-
Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese
-
DOI 10.1016/j.yebeh.2007.04.013, PII S1525505007001540
-
Kwan P, Baum L, Wong V, Ng PW, Lui CH, Sin NC, et al. Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese. Epilepsy Behav 2007;11:112-7. (Pubitemid 47087203)
-
(2007)
Epilepsy and Behavior
, vol.11
, Issue.1
, pp. 112-117
-
-
Kwan, P.1
Baum, L.2
Wong, V.3
Ng, P.W.4
Lui, C.H.5
Sin, N.C.6
Hui, A.C.F.7
Yu, E.8
Wong, L.K.S.9
-
34
-
-
34447501746
-
Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: A gene polymorphism perspective study
-
DOI 10.1097/FTD.0b013e318067ce90, PII 0000769120070600000007
-
Ebid AH, Ahmed MM, Mohammed SA. Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: A gene polymorphism perspective study. Ther Drug Monit 2007;29:305-12. (Pubitemid 47262260)
-
(2007)
Therapeutic Drug Monitoring
, vol.29
, Issue.3
, pp. 305-312
-
-
Mohammed Ebid, A.-H.I.1
Ahmed, M.M.M.2
Mohammed, S.A.3
-
35
-
-
35348848498
-
Association of polymorphisms in NR1I2 and ABCB1 genes with epilepsy treatment responses
-
Hung CC, Jen TJ, Kao PJ, Lin MS, Liou HH. Association of polymorphisms in NR1I2 and ABCB1 genes with epilepsy treatment responses. Pharmacogenomics 2007;8:1151-8.
-
(2007)
Pharmacogenomics
, vol.8
, pp. 1151-1158
-
-
Hung, C.C.1
Jen, T.J.2
Kao, P.J.3
Lin, M.S.4
Liou, H.H.5
-
36
-
-
4644230833
-
Failure to confirm association of a polymorphism in ABCB1 with multidrug-resistant epilepsy
-
Tan NC, Heron SE, Scheffer IE, Pelekanos JT, McMahon JM, Vears DF, et al. Failure to confirm association of a polymorphism in ABCB1 with multidrug-resistant epilepsy. Neurology 2004;63:1090-2. (Pubitemid 39287923)
-
(2004)
Neurology
, vol.63
, Issue.6
, pp. 1090-1092
-
-
Tan, N.C.K.1
Heron, S.E.2
Scheffer, I.E.3
Pelekanos, J.T.4
McMahon, J.M.5
Vears, D.F.6
Mulley, J.C.7
Berkovic, S.F.8
-
37
-
-
18244365827
-
Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment
-
DOI 10.1111/j.1528-1167.2005.46304.x
-
Sills GJ, Mohanraj R, Butler E, McCrindle S, Collier L, Wilson EA, et al. Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment. Epilepsia 2005;46:643-7. (Pubitemid 40628658)
-
(2005)
Epilepsia
, vol.46
, Issue.5
, pp. 643-647
-
-
Sills, G.J.1
Mohanraj, R.2
Butler, E.3
McCrindle, S.4
Collier, L.5
Wilson, E.A.6
Brodie, M.J.7
-
38
-
-
30744472610
-
Single nucleotide polymorphisms in the multidrug resistance 1 gene in Korean epileptics
-
DOI 10.1016/j.seizure.2005.11.001, PII S1059131105002128
-
Kim YO, Kim MK, Woo YJ, Lee MC, Kim JH, Park KW, et al. Single nucleotide polymorphisms in the multidrug resistance 1 gene in Korean epileptics. Seizure 2006;15:67-72. (Pubitemid 43092098)
-
(2006)
Seizure
, vol.15
, Issue.1
, pp. 67-72
-
-
Kim, Y.O.1
Kim, M.K.2
Woo, Y.J.3
Lee, M.C.4
Kim, J.H.5
Park, K.W.6
Kim, E.Y.7
Roh, Y.I.8
Kim, C.J.9
-
39
-
-
33744547260
-
Lack of association between C3435T nucleotide MDR1 genetic polymorphism and multidrug-resistant epilepsy
-
DOI 10.1016/j.seizure.2006.02.015, PII S1059131106000410
-
Kim DW, Kim M, Lee SK, Kang R, Lee SY. Lack of association between C3435T nucleotide MDR1 genetic polymorphism and multidrug-resistant epilepsy. Seizure 2006;15:344-7. (Pubitemid 43812238)
-
(2006)
Seizure
, vol.15
, Issue.5
, pp. 344-347
-
-
Kim, D.W.1
Kim, M.2
Lee, S.K.3
Kang, R.4
Lee, S.-Y.5
-
40
-
-
33745963092
-
Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: A prospective cohort study
-
DOI 10.1016/S1474-4422(06)70500-2, PII S1474442206705002
-
Leschziner G, Jorgensen AL, Andrew T, Pirmohamed M, Williamson PR, Marson AG, et al. Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: A prospective cohort study. Lancet Neurol 2006;5:668-76. (Pubitemid 44062410)
-
(2006)
Lancet Neurology
, vol.5
, Issue.8
, pp. 668-676
-
-
Leschziner, G.1
Jorgensen, A.L.2
Andrew, T.3
Pirmohamed, M.4
Williamson, P.R.5
Marson, A.G.6
Coffey, A.J.7
Middleditch, C.8
Rogers, J.9
Bentley, D.R.10
Chadwick, D.W.11
Balding, D.J.12
Johnson, M.R.13
-
41
-
-
37249003692
-
Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey
-
Ozgon GO, Bebek N, Gul G, Cine N. Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey. Eur Neurol 2007;59:67-70.
-
(2007)
Eur Neurol
, vol.59
, pp. 67-70
-
-
Ozgon, G.O.1
Bebek, N.2
Gul, G.3
Cine, N.4
-
42
-
-
33847366654
-
The controversial association of ABCB1 polymorphisms in refractory epilepsy: An analysis of multiple SNPs in an Irish population
-
DOI 10.1016/j.eplepsyres.2006.10.004, PII S0920121106004116
-
Shahwan A, Murphy K, Doherty C, Cavalleri GL, Muckian C, Dicker P, et al. The controversial association of ABCB1 polymorphisms in refractory epilepsy: An analysis of multiple SNPs in an Irish population. Epilepsy Res 2007;73:192-8. (Pubitemid 46331873)
-
(2007)
Epilepsy Research
, vol.73
, Issue.2
, pp. 192-198
-
-
Shahwan, A.1
Murphy, K.2
Doherty, C.3
Cavalleri, G.L.4
Muckian, C.5
Dicker, P.6
McCarthy, M.7
Kinirons, P.8
Goldstein, D.9
Delanty, N.10
-
43
-
-
58149268938
-
No association of ABCB1 polymorphisms with drug-refractory epilepsy in a north Indian population
-
Lakhan R, Misra UK, Kalita J, Pradhan S, Gogtay NJ, Singh MK, et al. No association of ABCB1 polymorphisms with drug-refractory epilepsy in a north Indian population. Epilepsy Behav 2009;14:78-82.
-
(2009)
Epilepsy Behav
, vol.14
, pp. 78-82
-
-
Lakhan, R.1
Misra, U.K.2
Kalita, J.3
Pradhan, S.4
Gogtay, N.J.5
Singh, M.K.6
-
44
-
-
77955847469
-
Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients
-
Grover S, Bala K, Sharma S, Gourie-Devi M, Baghel R, Kaur H, et al. Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients. Biochimie 2010:92:1207-12.
-
(2010)
Biochimie
, vol.92
, pp. 1207-1212
-
-
Grover, S.1
Bala, K.2
Sharma, S.3
Gourie-Devi, M.4
Baghel, R.5
Kaur, H.6
-
45
-
-
63849243164
-
Polymorphism of the MDR1/ABCB1 C3435T drug-transporter and resistance to anticonvulsant drugs: A meta-analysis
-
Bournissen FG, Moretti ME, Juurlink DN, Koren G, Walker M, Finkelstein Y. Polymorphism of the MDR1/ABCB1 C3435T drug-transporter and resistance to anticonvulsant drugs: A meta-analysis. Epilepsia 2009;50:898-903.
-
(2009)
Epilepsia
, vol.50
, pp. 898-903
-
-
Bournissen, F.G.1
Moretti, M.E.2
Juurlink, D.N.3
Koren, G.4
Walker, M.5
Finkelstein, Y.6
-
46
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996;273:1516-7. (Pubitemid 26301653)
-
(1996)
Science
, vol.273
, Issue.5281
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
47
-
-
0036517472
-
A comprehensive review of genetic association studies
-
DOI 10.1097/00125817-200203000-00002
-
Hirschhorn JN, Lohmueller K, Byrne E, Hirschhorn K. A comprehensive review of genetic association studies. Genet Med 2002;4:45-61. (Pubitemid 44698579)
-
(2002)
Genetics in Medicine
, vol.4
, Issue.2
, pp. 45-61
-
-
Hirschhorn, J.N.1
Lohmueller, K.2
Byrne, E.3
Hirschhorn, K.4
-
48
-
-
0038813649
-
Genetic associations: False or true?
-
DOI 10.1016/S1471-4914(03)00030-3
-
Ioannidis JP. Genetic associations: False or true? Trends Mol Med 2003;9:135-8. (Pubitemid 36626701)
-
(2003)
Trends in Molecular Medicine
, vol.9
, Issue.4
, pp. 135-138
-
-
Ioannidis, J.P.A.1
-
49
-
-
0037442235
-
Genetic associations in large versus small studies: An empirical assessment
-
DOI 10.1016/S0140-6736(03)12516-0
-
Ioannidis JP, Trikalinos TA, Ntzani EE, Contopoulos-Ioannidis DG. Genetic associations in large versus small studies: An empirical assessment. Lancet 2003;361:567-71. (Pubitemid 36207475)
-
(2003)
Lancet
, vol.361
, Issue.9357
, pp. 567-571
-
-
Ioannidis, J.P.A.1
Trikalinos, T.A.2
Ntzani, E.E.3
Contopoulos-Ioannidis, D.G.4
-
50
-
-
20444394309
-
Association of genetic loci: Replication or not, that is the question [2]
-
Sisodiya S, Soranzo N, Wood NW, Goldstein DB. Association of genetic loci: Replication or not, that is the question. Neurology 2005;64:1989. (Pubitemid 40800732)
-
(2005)
Neurology
, vol.64
, Issue.11
, pp. 1989
-
-
Sisodiya, S.1
Soranzo, N.2
Wood, N.W.3
Goldstein, D.B.4
-
51
-
-
33645278654
-
Defining intractability: Comparisons among published definitions
-
Berg AT, Kelly MM. Defining intractability: Comparisons among published definitions. Epilepsia 2006; 47: 431-6.
-
(2006)
Epilepsia
, vol.47
, pp. 431-436
-
-
Berg, A.T.1
Kelly, M.M.2
-
52
-
-
77954625557
-
Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
-
Kwan P, Arzimanoglou A, Berg AT, Brodie MJ, Allen Hauser W, Mathern G, et al. Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 2010;51:1069-77.
-
(2010)
Epilepsia
, vol.51
, pp. 1069-1077
-
-
Kwan, P.1
Arzimanoglou, A.2
Berg, A.T.3
Brodie, M.J.4
Allen Hauser, W.5
Mathern, G.6
-
53
-
-
36949012486
-
Drug resistance in epilepsy: More twists in the tale [1]
-
DOI 10.1111/j.1528-1167.2007.01260-1.x
-
Sisodiya SM, Goldstein DB. Drug resistance in epilepsy: More twists in the tale. Epilepsia 2007;48:2369-70. (Pubitemid 350243407)
-
(2007)
Epilepsia
, vol.48
, Issue.12
, pp. 2369-2370
-
-
Sisodiya, S.M.1
Goldstein, D.B.2
-
54
-
-
33845866924
-
Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays
-
DOI 10.1124/jpet.106.102491
-
Baltes S, Fedrowitz M, Tortos CL, Potschka H, Löscher W. Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays. J Pharmacol Exp Ther 2007;320:331-43. (Pubitemid 46025748)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.320
, Issue.1
, pp. 331-343
-
-
Baltes, S.1
Fedrowitz, M.2
Tortos, C.L.3
Potschka, H.4
Loscher, W.5
-
55
-
-
0035036730
-
Carbamazepine is not a substrate for P-glycoprotein
-
DOI 10.1046/j.1365-2125.2001.01359.x
-
Owen A, Pirmohamed M, Tettey JN, Morgan P, Chadwick D, Park BK. Carbamazepine is not a substrate for P-glycoprotein. Br J Clin Pharmacol 2001;51:345-9. (Pubitemid 32391490)
-
(2001)
British Journal of Clinical Pharmacology
, vol.51
, Issue.4
, pp. 345-349
-
-
Owen, A.1
Pirmohamed, M.2
Tettey, J.N.3
Morgan, P.4
Chadwick, D.5
Kevin Park, B.6
-
56
-
-
0035900333
-
P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain
-
Potschka H, Fedrowitz M, Löscher W. P-Glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain. Neuroreport 2001;12:3557-60. (Pubitemid 33065498)
-
(2001)
NeuroReport
, vol.12
, Issue.16
, pp. 3557-3560
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
57
-
-
22744440362
-
Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases
-
DOI 10.1016/j.pneurobio.2005.04.006, PII S0301008205000444
-
Löscher W, Potschka H. Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases. Prog Neurobiol 2005;76:22-76. (Pubitemid 41033402)
-
(2005)
Progress in Neurobiology
, vol.76
, Issue.1
, pp. 22-76
-
-
Loscher, W.1
Potschka, H.2
-
58
-
-
27644474133
-
RLIP76, a non-ABC transporter, and drug resistance in epilepsy
-
Awasthi S, Hallene KL, Fazio V, Singhal SS, Cucullo L, Awasthi YC, et al. RLIP76, a non-ABC transporter, and drug resistance in epilepsy. BMC Neurosci 2005;6:61.
-
(2005)
BMC Neurosci
, vol.6
, pp. 61
-
-
Awasthi, S.1
Hallene, K.L.2
Fazio, V.3
Singhal, S.S.4
Cucullo, L.5
Awasthi, Y.C.6
-
59
-
-
34247104934
-
Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy
-
DOI 10.1111/j.1528-1167.2007.00926.x
-
Soranzo N, Kelly L, Martinian L, Burley MW, Thom M, Sali A, et al. Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy. Epilepsia 2007;48:674-83. (Pubitemid 46587613)
-
(2007)
Epilepsia
, vol.48
, Issue.4
, pp. 674-683
-
-
Soranzo, N.1
Kelly, L.2
Martinian, L.3
Burley, M.-W.4
Thom, M.5
Sali, A.6
Kroetz, D.L.7
Goldstein, D.B.8
Sisodiya, S.M.9
-
60
-
-
23444437212
-
Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: Where to from here?
-
DOI 10.1093/brain/awh524
-
Cavalleri GL, Lynch JM, Depondt C, Burley MW, Wood NW, Sisodiya SM, et al. Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: Where to from here? Brain 2005;128:1832-40. (Pubitemid 41373654)
-
(2005)
Brain
, vol.128
, Issue.8
, pp. 1832-1840
-
-
Cavalleri, G.L.1
Lynch, J.M.2
Depondt, C.3
Burley, M.-W.4
Wood, N.W.5
Sisodiya, S.M.6
Goldstein, D.B.7
-
61
-
-
77950221224
-
Advances in genomic analysis of stroke: What have we learned and where are we headed?
-
Lanktree MB, Dichgans M, Hegele RA. Advances in genomic analysis of stroke: What have we learned and where are we headed? Stroke 2010;41:825-32.
-
(2010)
Stroke
, vol.41
, pp. 825-832
-
-
Lanktree, M.B.1
Dichgans, M.2
Hegele, R.A.3
-
63
-
-
65949124249
-
Genome wide Association Studies - Illuminating Biologic Pathways
-
Hirschhorn JN. Genome wide Association Studies - Illuminating Biologic Pathways. N Engl J Med 2009;360:1699-701.
-
(2009)
N Engl J Med
, vol.360
, pp. 1699-701
-
-
Hirschhorn, J.N.1
-
64
-
-
62149091854
-
A neurologist's guide to genome-wide association studies
-
Mullen SA, Crompton DE, Carney PW, Helbig I, Berkovic SF. A neurologist's guide to genome-wide association studies. Neurology 2009;72:558-65.
-
(2009)
Neurology
, vol.72
, pp. 558-565
-
-
Mullen, S.A.1
Crompton, D.E.2
Carney, P.W.3
Helbig, I.4
Berkovic, S.F.5
-
65
-
-
34347335667
-
Guilt beyond a reasonable doubt
-
DOI 10.1038/ng0707-813, PII NG0707813
-
Altshuler D, Daly M. Guilt beyond a reasonable doubt. Nat Genet 2007;39:813-5. (Pubitemid 47014482)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 813-815
-
-
Altshuler, D.1
Daly, M.2
-
66
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
DOI 10.1038/nature05887, PII NATURE05887
-
Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007;447:1087-93. (Pubitemid 47014426)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.P.4
Thompson, D.5
Ballinger, D.G.6
Struewing, J.P.7
Morrison, J.8
Field, H.9
Luben, R.10
Wareham, N.11
Ahmed, S.12
Healey, C.S.13
Bowman, R.14
Meyer, K.B.15
Haiman, C.A.16
Kolonel, L.K.17
Henderson, B.E.18
Le Marchand, L.19
Brennan, P.20
Sangrajrang, S.21
Gaborieau, V.22
Odefrey, F.23
Shen, C.-Y.24
Wu, P.-E.25
Wang, H.-C.26
Eccles, D.27
Evans, D.G.28
Peto, J.29
Fletcher, O.30
Johnson, N.31
Seal, S.32
Stratton, M.R.33
Rahman, N.34
Chenevix-Trench, G.35
Bojesen, S.E.36
Nordestgaard, B.G.37
Axelsson, C.K.38
Garcia-Closas, M.39
Brinton, L.40
Chanock, S.41
Lissowska, J.42
Peplonska, B.43
Nevanlinna, H.44
Fagerholm, R.45
Eerola, H.46
Kang, D.47
Yoo, K.-Y.48
Noh, D.-Y.49
Ahn, S.-H.50
Hunter, D.J.51
Hankinson, S.E.52
Cox, D.G.53
Hall, P.54
Wedren, S.55
Liu, J.56
Low, Y.-L.57
Bogdanova, N.58
Schurmann, P.59
Dork, T.60
Tollenaar, R.A.E.M.61
Jacobi, C.E.62
Devilee, P.63
Klijn, J.G.M.64
Sigurdson, A.J.65
Doody, M.M.66
Alexander, B.H.67
Zhang, J.68
Cox, A.69
Brock, I.W.70
MacPherson, G.71
Reed, M.W.R.72
Couch, F.J.73
Goode, E.L.74
Olson, J.E.75
Meijers-Heijboer, H.76
Van Den Ouweland, A.77
Uitterlinden, A.78
Rivadeneira, F.79
Milne, R.L.80
Ribas, G.81
Gonzalez-Neira, A.82
Benitez, J.83
Hopper, J.L.84
McCredie, M.85
Southey, M.86
Giles, G.G.87
Schroen, C.88
Justenhoven, C.89
Brauch, H.90
Hamann, U.91
Ko, Y.-D.92
Spurdle, A.B.93
Beesley, J.94
Chen, X.95
Mannermaa, A.96
Kosma, V.-M.97
more..
-
67
-
-
77950220916
-
Stroke genome-wide association studies. The large numbers imperative
-
Meschia JF. Stroke Genome-Wide Association Studies. The Large Numbers Imperative. Stroke 2010;41:579.
-
(2010)
Stroke
, vol.41
, pp. 579
-
-
Meschia, J.F.1
|