Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study

Lancet Neurology

Volumn 5, Issue 8, 2006, Pages 668-676

  Leschziner, Guy ^a,b   Jorgensen, Andrea L ^c   Andrew, Toby ^d   Pirmohamed, Munir ^c   Williamson, Paula R ^c   Marson, Anthony G ^c   Coffey, Alison J ^b   Middleditch, Claire ^a   Rogers, Jane ^b   Bentley, David R ^b   Chadwick, David W ^c   Balding, David J ^a   Johnson, Michael R ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTICONVULSIVE AGENT; CARBAMAZEPINE; GABAPENTIN; LAMOTRIGINE; MULTIDRUG RESISTANCE PROTEIN 1; OXCARBAZEPINE; TOPIRAMATE; UNCLASSIFIED DRUG; VALPROIC ACID;

ARTICLE; COHORT ANALYSIS; CONFIDENCE INTERVAL; DATA ANALYSIS; DEMOGRAPHY; DISEASE ASSOCIATION; DRUG RESPONSE; DRUG WITHDRAWAL; EPILEPSY; FEMALE; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOME; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; REMISSION; SEIZURE; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT OUTCOME; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

ADULT; ANTICONVULSANTS; ATP-BINDING CASSETTE TRANSPORTERS; CASE-CONTROL STUDIES; COHORT STUDIES; DRUG RESISTANCE, MULTIPLE; EPILEPSY; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; TIME FACTORS;

EID: 33745963092     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(06)70500-2     Document Type: Article

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