Translating cancer research by synthetic biology

Molecular BioSystems

Volumn 7, Issue 6, 2011, Pages 1802-1810

  Shankar, Sumitra ^a   Pillai, M Radhakrishna ^a  

^a RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT;

ANIMAL; BIOENGINEERING; DRUG DELIVERY SYSTEM; DRUG DEVELOPMENT; DRUG SCREENING; HUMAN; METHODOLOGY; NEOPLASM; PATHOLOGY; PROTEIN ENGINEERING; REVIEW; SYNTHETIC BIOLOGY; TRANSLATIONAL RESEARCH;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOENGINEERING; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; NEOPLASMS; PROTEIN ENGINEERING; SYNTHETIC BIOLOGY; TRANSLATIONAL MEDICAL RESEARCH;

EID: 79956118535     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/c1mb05016h     Document Type: Review

References (66)

1. A. Moore A day of systems and synthetic biology for non-experts BioEssays 2009 31 119 124
2. J. W. Chin Modular approaches to expanding the functions of living matter Nat. Chem. Biol. 2006 2 6 304 311 (Pubitemid 43787210)
3. C. H. Martin D. R. Nielsen K. V. Solomon K. L. Prather Review Synthetic Metabolism: Engineering Biology at the Protein and Pathway Scales Chem. Biol. 2009 16 3 277 286
4. A. Villalobos J. E. Ness C. Gustafsson J. Minshill et al., Gene Designer: a synthetic biology tool for construction artificial DNA segments BMC Bioinformatics 2006 7 285
5. N. Yeung Y. W. Lin Y. G. Gao X. Zhao et al., Rational design of a structural and functional nitric oxide reductase Nature 2009 462 1079 1084
6. Y. Hori Y. Suguira Conversion of Antennapaedia Homeodomain to Zinc finger like domain: Zn(ii) induced change in protein conformation and DNA binding J. Am. Chem. Soc. 2002 124 32 9362 9363 (Pubitemid 34856209)
7. K. A. Haynes P. A. Silver Eukaryotic systems broaden the scope of synthetic biology J. Cell Biol. 2009 187 5 589 596
8. J. D. Bloom F. H. Arnold In the light of directed evolution: Pathways of adaptive protein evolution Proc. Natl. Acad. Sci. U. S. A. 2009 106 9995 10000
9. B. P. Kramer A. U. Viretta M. Daoud-El-Baba D. Aubel et al., An engineered epigenetic transgene switch in mammalian cells Nat. Biotechnol. 2004 22 867 70 (Pubitemid 38886606)
10. M. Gitzinger C. Kemmer M. D. El-baba W. Weber et al., Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin Proc. Natl. Acad. Sci. U. S. A. 2009 106 26 10638 10643
11. P. L. Howard M. C. Chia D. Rizzo F. F. Liu et al., Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins Proc. Natl. Acad. Sci. U. S. A. 2003 100 11267 11272 (Pubitemid 37205924)
12. V. Rolli M. Galawitz T. Wossning A. Flemming et al., Amplification of B Cell Antigen Receptor Signaling by a Syk/ITAM Positive Feedback Loop Mol. Cell 2002 10 1057 1069 (Pubitemid 36001972)
13. B. Di C. Funaya C. Antony M. Knop et al., Reconstitution of Mdm2-Dependent Post-Translational Modifications of p53 in Yeast PLoS One 2008 1 1 9
14. S. W. Rowlinson H. Yoshizato J. L. Barclay A. J. Brooks et al., An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway Nat. Cell Biol. 2009 10 740 747 (Pubitemid 351780137)
15. B. R. Conklin E. C. Hsiao S. Claeysen A. Dumuis et al., Engineering GPCR signaling pathways with RASSLs Nat. Methods 2008 5 673 678
16. W. A. Lim Designing customized cell signaling circuits Nat. Rev. Mol. Cell Biol. 2010 11 393 403
17. A. Levskaya O. D. Weiner W. A. Lim C. A. Voigt Spatiotemporal control of cell signalling using a light switchable protein interaction Nature 2009 461 997 1001
18. H. Neumann K. Wang L. Davis M. Garcia-Alai et al., Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome Nature 2010 464 7287 441 444
19. e-acetyllysine in recombinant proteins Nat. Chem. Biol. 2008 4 232 234 (Pubitemid 351414829)
20. M. R. Benoit D. Mayer Y. Barak I. Y. Chen et al., Visualizing Implanted Tumors in Mice with Magnetic Resonance Imaging Using Magnetotactic Bacteria Clin. Cancer Res. 2009 15 13 5170 5177
21. M. Edinger Y. A. Cao M. R. Verneris M. H. Bachmann et al., Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging Blood 2003 101 640 648 (Pubitemid 36077588)
22. M. G. Shapiro G. G. Westmeyer P. A. Romero J. O. Szablowski et al., Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine Nat. Biotechnol. 2010 28 3 264 270
23. E. Cerasoli B. K. Sharpe D. N. Woolfson 2005, ZiCo: A Peptide Designed to Switch Folded State upon Binding Zinc J. Am. Chem. Soc. 2006 127 15008 15009 (Pubitemid 41547351)
24. G. Peng U. Tisch O. Adams M. Hakim et al., Diagnosing lung cancer in exhaled breath using gold nanoparticles Nat. Nanotechnol. 2009 4 10 669 673
25. Q. T. Nguyen E. S. Olson T. A. Aguilera T. Jiang et al., Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival Proc. Natl. Acad. Sci. U. S. A. 2010 107 9 4317 4322
26. T. Z. Butlera M. Pavlenokb I. M. Derringtona M. Niederweisb et al., Single-molecule DNA detection with an engineered MspA protein nanopore Proc. Natl. Acad. Sci. U. S. A. 2008 105 20647 20652
27. V. J. Martin D. J. Pitera S. T. Withers J. D. Newman et al., Engineering a mevalonate pathway in Escherichia coli for production of terpenoids Nat. Biotechnol. 2003 21 796 802 (Pubitemid 36791399)
28. B. Engels P. Dahm S. Jennewein Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production Yeast 2008 10 201 206
29. C. Khosla S. Kapur D. E. Cane Revisiting the modularity of modular polyketide synthases Curr. Opin. Chem. Biol. 2009 13 135 143
30. K. Baker C. Bleczinski H. Lin G. Salazar-jimenez D. Sengupta S. Krane V. W. Cornish Chemical complementation: A reaction-independent high-throughput genetic assay for enzyme catalysis Proc. Natl. Acad. Sci. U. S. A. 2002 99 26 16537 16542 (Pubitemid 36034008)
31. V. Gonzalez-Nicolini C. Fux M. Fussenegger A novel mammalian cell-based approach for the discovery of anticancer drugs with reduced cytotoxicity on non-dividing cells Invest. New Drugs 2004 22 253 262 (Pubitemid 39012564)
32. S. Schlehuber A. Skerra Lipocalins in drug discovery: from natural ligand-binding proteins to 'anticalins' Drug Discovery Today 2005 10 1 23 33 (Pubitemid 40164816)
33. J. Winkler P. Martin-killias A. Plückthun EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins Mol. Cancer Ther. 2009 8 9 2674 2683
34. C. Zahnd F. Pecorari N. Straumann E. Wyler et al., Selection and characterization of Her2 binding-designed ankyrin repeat proteins J. Biol. Chem. 2006 281 35167 75 (Pubitemid 46036556)
35. A. C. Forster V. W. Cornish S. C. Blacklow Pure translation display Anal. Biochem. 2004 333 358 364 (Pubitemid 39278060)
36. L. M. Dedkova N. E. Fahmi S. Y. Golovine S. M. Hecht Enhanced d-amino acid incorporation into protein by modified ribosomes J. Am. Chem. Soc. 2003 125 6616 6617 (Pubitemid 36667430)
37. M. Ehrbar R. Schoenmakers E. H. Christen M. Fussenger et al., Drug-sensing hydrogels for the inducible release of biopharmaceuticals Nat. Mater. 2008 7 800 804
38. V. Schellenberger C. Wang N. C. Geething B. J. Spink et al., A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner Nat. Biotechnol. 2009 27 12 1186 1190
39. J. R. McDaniel D. J. Callahan A. Chilkoti Drug delivery to solid tumors by elastin-like polypeptides Adv. Drug Delivery Rev. 2010 62 15 1456 1467
40. J. C. Anderson E. J. Clarke A. P. Arkin C. A. Voigt Environmentally controlled invasion of cancer cells by engineered bacteria J. Mol. Biol. 2006 355 619 627 (Pubitemid 41817623)
41. S. C. Liu N. P. Minton A. J. Giaccia J. M. Brown Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosis Gene Ther. 2002 9 291 296 (Pubitemid 34256904)
42. N. Yang X. Zhu L. Chen S. Li et al, Oral administration of attenuated S. typhimurium carrying shRNA-expressing vectors as a cancer therapeutic Cancer Biol. Ther. 2008 7 1 145 51
43. S. Mueller J. R. Coleman E. Wimmer Putting Synthesis into Biology: A Viral View of Genetic Engineering through De Novo Gene and Genome Synthesis Chem. Biol. 2009 16 3 337 347
44. M. Ramachandra A. Rahman A. Zou M. Vaillancourt et al., Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy Nat. Biotechnol. 2001 19 11 1035 41 (Pubitemid 33041887)
45. A. E. Friedland T. K. Lu X. Wang D. Shi et al., Synthetic gene networks that count Science 2009 324 1199 1202
46. L. Zhang W. J. Gasper S. A. Stass O. B. Ioffe et al., Angiogenic Inhibition Mediated by a DNAzyme That Targets Vascular Endothelial Growth Factor Receptor 2 Cancer Res. 2002 62 5463 5469
47. E. T. Kool Hydrogen bonding, base stacking, and steric effects in DNA replication Annu. Rev. Biophys. Biomol. Struct. 2001 30 1 22 (Pubitemid 32566154)
48. R. R. White J. A. Roy K. D. Viles B. A. Sullenger et al., A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated Tie2 activation and function Angiogenesis 2008 11 395 401
49. J. Wang H. Jiang F. Liu In vitro selection of novel RNA ligands that bind human cytomegalovirus and block viral infection RNA 2000 6 571 583 (Pubitemid 30212235)
50. M. S. D. Kormann G. Hasenpusch M. K. Aneja G. Nica et al., Expression of therapeutic proteins after delivery of chemically modified mRNA in mice Nat. Biotechnol. 2011 29 2 154 157
51. G. Tavernier O. Andries J. Demeester N. N. Sanders et al., mRNA as gene therapeutic: How to control expression J. Controlled Release 2010 10.1016/j.jconrel.2010.10.020
52. A. Yamamoto M. Kormann J. Rosenecker C. Rudolph Current prospects for mRNA delivery Eur. J. Pharm. Biopharm. 2009 71 484 489
53. T. Hayashi D. A. Lamba A. Slowik T. A. Reh et al., A method for stabilizing RNA for transfection that allows control of expression duration Dev. Dyn. 2010 239 2034 2040
54. P. W. K. Rothemund Folding DNA to create nanoscale shapes and patterns Nature 2006 440 297 302
55. E. S. Andersen M. Dong M. M. Neilsen K. Jahn et al., Self-assembly of a nanoscale DNA box with a controllable lid Nature 2009 459 73 77
56. J. O. McNamara E. R. Andrechek Y. Wang K. D. Viles et al., Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras Nat. Biotechnol. 2006 24 1005 1015 (Pubitemid 44215395)
57. S. Venkataraman R. M. Dirks C. T. Ueda N. A. Pierce Selective cell death mediated by small conditional RNAs Proc. Natl. Acad. Sci. U. S. A. 2010 107 39 16777 16782
58. S. J. Culler K. G. Hoff C. D. Smolke Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins Science 2010 330 6008 1251 1255
59. P. M. Boyle P. A. Silver Harnessing nature's toolbox: regulatory elements for synthetic biology J. R. Soc. Interface 2009 6 S535 S546
60. J. Sinha S. J. Reyes J. P. Gallivan Reprogramming bacteria to seek and destroy an herbicide Nat. Chem. Biol. 2010 6 464 470
61. C. R. Reis A. M. Van der Sloot E. Szegezdi A. Natoni et al., Enhancement of Antitumor Properties of rhTRAIL by Affinity Increase toward Its Cell 2009 5 2180 2191
62. K. Chen C. Wu C. Chang W. C. Lu et al., Article Directed Evolution of a Lysosomal Enzyme with Enhanced Activity at Neutral pH by Mammalian Cell-Surface Display Chem. Biol. 2008 15 12 1277 1286 (Pubitemid 352841466)
63. 6 alkylguanine DNA alkyltransferase as a means to enhance chemotherapy Cancer Treat. Rev. 2006 32 4 261 276 (Pubitemid 44522815)
64. Y. Santiago E. Chan P. Liu S. Orlando et al., Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases Proc. Natl. Acad. Sci. U. S. A. 2008 105 15 5809 5814 (Pubitemid 351758454)
65. B. Walker N. Walsh H. Bayley Genetically engineered protease-activated triggers in a pore forming protein Mat. Res. Soc. Sym. Proc. 1994 330 209
66. C. D. Cantoblanco T. Knight Synthetic biology: something old, something new BioEssays 2010 32 267 270