-
1
-
-
47149115483
-
Novel fluorinated acridone derivatives. Part 1: Synthesis and evaluation as potential anticancer agents
-
Fadeyi, O.O.; Adamson, S.T.; Myles, E.L.; Okoro, CO. Novel fluorinated acridone derivatives. Part 1: Synthesis and evaluation as potential anticancer agents. Bioorg. Med. Chem. Lett., 2008, 18, 4172-4176.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 4172-4176
-
-
Fadeyi, O.O.1
Adamson, S.T.2
Myles, E.L.3
Okoro, C.O.4
-
2
-
-
33747192681
-
Synthesis and in vitro antitumor evaluation of some indeno[1,2-c] pyrazol(in)es substituted with sulfonamide, sulfonylurea(-thiourea) pharmacophores, and some derived thiazole ring systems
-
Sherif, A.; Rostom, F. Synthesis and in vitro antitumor evaluation of some indeno[1,2-c]pyrazol(in)es substituted with sulfonamide, sulfonylurea(-thiourea) pharmacophores, and some derived thiazole ring systems. Bioorg. Med. Chem., 2006, 14, 6475-6485.
-
(2006)
Bioorg. Med. Chem.
, vol.14
, pp. 6475-6485
-
-
Sherif, A.1
Rostom, F.2
-
3
-
-
85038514121
-
-
http://www.who.int/mediacentre/factsheets/fs297/en/index.html
-
-
-
-
4
-
-
33645218036
-
Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis
-
Hsu, Y.L.; Kuo, P.L.; Tzeng, W.S.; Lin, C.C. Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis. Food Chem. Toxicol., 2006, 44, 704-713.
-
(2006)
Food Chem. Toxicol.
, vol.44
, pp. 704-713
-
-
Hsu, Y.L.1
Kuo, P.L.2
Tzeng, W.S.3
Lin, C.C.4
-
5
-
-
0028268289
-
The epidermal growth factor receptor as a target for therapy in breast carcinoma
-
Baselga, J.; Mendelsohn, J. The epidermal growth factor receptor as a target for therapy in breast carcinoma. Breast Cancer Res. Treat., 1994, 29, 127-138. (Pubitemid 24104844)
-
(1994)
Breast Cancer Research and Treatment
, vol.29
, Issue.1
, pp. 127-138
-
-
Baselga, J.1
Mendelsohn, J.2
-
6
-
-
75149145989
-
Synthesis and biological evaluation of simple methoxylated chalcones as anticancer, anti-inflammatory and antioxidant agents
-
Bandgar, B.P.; Gawande, S.S.; Bodade, R.G.; Totre, J.V.; Khobragade, C.N. Synthesis and biological evaluation of simple methoxylated chalcones as anticancer, anti-inflammatory and antioxidant agents. Bioorg. Med. Chem., 2010, 18, 1364-1370.
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 1364-1370
-
-
Bandgar, B.P.1
Gawande, S.S.2
Bodade, R.G.3
Totre, J.V.4
Khobragade, C.N.5
-
7
-
-
4644330224
-
Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model
-
DOI 10.1016/j.bcp.2004.05.003, PII S0006295204003065
-
Martirosyan, A.; Rahim-Bata, R.; Freeman, A.; Clarke, C.; Howard, R.; Strobl, J. Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human cancer cell model. Biochem. Pharmacol., 2004, 68, 1729-1738. (Pubitemid 39278495)
-
(2004)
Biochemical Pharmacology
, vol.68
, Issue.9
, pp. 1729-1738
-
-
Martirosyan, A.R.1
Rahim-Bata, R.2
Freeman, A.B.3
Clarke, C.D.4
Howard, R.L.5
Strobl, J.S.6
-
8
-
-
50349088132
-
Synthesis and antiproliferative activity in vitro of novel (2-buthynyl)thioquinolines
-
Mól, W.; Matyja, M.; Filip, B.; Wietrzyk, S. Synthesis and antiproliferative activity in vitro of novel (2-buthynyl)thioquinolines. Bioorg. Med. Chem., 2008, 16, 8136-8141.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 8136-8141
-
-
Mól, W.1
Matyja, M.2
Filip, B.3
Wietrzyk, S.4
-
9
-
-
34250170875
-
Novel potent antimitotic heterocyclic ketones: Synthesis, antiproliferative activity, and structure-activity relationships
-
DOI 10.1016/j.bmcl.2007.04.048, PII S0960894X07004933
-
Hu, L.; Jiang, J-D.; Qu, J.; Li, Y.; Jin, J.; Li, Z-R.; Boykin, D.W. Novel potent antimitotic heterocyclic ketones: Synthesis, antiproliferative activity, and structure-activity relationships. Bioorg. Med. Chem. Lett., 2007, 17, 3613-3617. (Pubitemid 46898827)
-
(2007)
Bioorganic and Medicinal Chemistry Letters
, vol.17
, Issue.13
, pp. 3613-3617
-
-
Hu, L.1
Jiang, J.-d.2
Qu, J.3
Li, Y.4
Jin, J.5
Li, Z.-r.6
Boykin, D.W.7
-
10
-
-
77950867152
-
Synthesis and antiproliferative activity of oxazinocarbazole and NN-bis(carbazolylmethyl)amine derivatives
-
Issa, S.; Walchshofer, N.; Kassab, I.; Termoss, H.; Chamat, S.; Geahchan, A.; Bouaziz, Z. Synthesis and antiproliferative activity of oxazinocarbazole and NN-bis(carbazolylmethyl)amine derivatives. Eur. J. Med. Chem., 2010, 45, 2567-2577.
-
(2010)
Eur. J. Med. Chem.
, vol.45
, pp. 2567-2577
-
-
Issa, S.1
Walchshofer, N.2
Kassab, I.3
Termoss, H.4
Chamat, S.5
Geahchan, A.6
Bouaziz, Z.7
-
11
-
-
56049127128
-
Antiproliferative and anti-tumor activity of organotin compounds
-
Hadjikakou, S.K.; Hadjiliadis, N. Antiproliferative and anti-tumor activity of organotin compounds. Coord. Chem. Rev., 2009, 253, 235-249.
-
(2009)
Coord. Chem. Rev.
, vol.253
, pp. 235-249
-
-
Hadjikakou, S.K.1
Hadjiliadis, N.2
-
12
-
-
77955550077
-
Design and synthesis of chloroquine analogs with anti-breast cancer property
-
Solomon, V.R.; Hu, C.; Lee, H. Design and synthesis of chloroquine analogs with anti-breast cancer property. Eur. J. Med. Chem., 2010, 45, 3916-3923.
-
(2010)
Eur. J. Med. Chem.
, vol.45
, pp. 3916-3923
-
-
Solomon, V.R.1
Hu, C.2
Lee, H.3
-
13
-
-
73949084441
-
Hybrid pharmacophore design and synthesis of isatin-benzothiazole analogs for their anti-breast cancer activity
-
Solomon, V.R.; Hu, C.; Lee, H. Hybrid pharmacophore design and synthesis of isatin-benzothiazole analogs for their anti-breast cancer activity. Bioorg. Med. Chem., 2009, 17, 7585-7592.
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 7585-7592
-
-
Solomon, V.R.1
Hu, C.2
Lee, H.3
-
14
-
-
75849120061
-
Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: A hybrid pharmacophore approach
-
Solomon, V.R.; Hu, C.; Lee, H. Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach. Bioorg. Med. Chem., 2010, 18, 1563-1572.
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 1563-1572
-
-
Solomon, V.R.1
Hu, C.2
Lee, H.3
-
15
-
-
0003465316
-
-
Elsevier Science Publishers B. V: The Netherlands
-
Agarwala, P.K. Carbon-13 NMR of flavonoids. Elsevier Science Publishers B. V: The Netherlands, 1989.
-
(1989)
Carbon-13 NMR of Flavonoids
-
-
Agarwala, P.K.1
-
16
-
-
79952707103
-
Mosquito larvicidal studies of some chalcone analogues and their derived products: Structure-activity relationship analysis
-
doi10.1007/s00044-010-9305-6
-
Begum, N.A.; Roy, N.; Laskar, R.A.; Roy, K. Mosquito larvicidal studies of some chalcone analogues and their derived products: structure-activity relationship analysis. Med. Chem. Res., 2010, doi10.1007/s00044-010-9305-6.
-
(2010)
Med. Chem. Res.
-
-
Begum, N.A.1
Roy, N.2
Laskar, R.A.3
Roy, K.4
-
17
-
-
20144367578
-
Chalcones: An update on cytotoxic and hemoprotective properties
-
Go, M.L.; Wu, X.; Liu, X.L. Chalcones: an update on cytotoxic and hemoprotective properties. Curr. Med. Chem., 2005, 12, 481-499.
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 481-499
-
-
Go, M.L.1
Wu, X.2
Liu, X.L.3
-
18
-
-
65649087484
-
Chalcones: A valid scaffold for monoamine oxidases inhibitors
-
Chimenti, F.; Fioravanti, R.; Bolasco, A.; Chimenti, P.; Secci, D.; Rossi, R.; Ya'ñez, M.; Orallo, F.; Ortuso, F.; Alcaro, S. Chalcones: A valid scaffold for monoamine oxidases inhibitors. J. Med. Chem., 2009, 52, 2818-2824.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2818-2824
-
-
Chimenti, F.1
Fioravanti, R.2
Bolasco, A.3
Chimenti, P.4
Secci, D.5
Rossi, R.6
Ya'Ñez, M.7
Orallo, F.8
Ortuso, F.9
Alcaro, S.10
-
19
-
-
0035818913
-
Antimalarial alkoxylated and hydroxylated chalones: Structure-activity relationship analysis
-
DOI 10.1021/jm0101747
-
Liu, M.; Wilairat, P.; Go, M-L. Antimalarial alkoxylated and hydroxylated chalones: Structure-activity relationship analysis. J. Med. Chem., 2001, 44, 4443-4452. (Pubitemid 33131668)
-
(2001)
Journal of Medicinal Chemistry
, vol.44
, Issue.25
, pp. 4443-4452
-
-
Liu, M.1
Wilairat, P.2
Go, M.-L.3
-
20
-
-
0032080796
-
Potent antimitotic and cell growth inhibitory properties of substituted chalcones
-
DOI 10.1016/S0960-894X(98)00162-0, PII S0960894X98001620
-
Ducki, S.; Forrest, R.; Hadfield, J.A.; Kendall, A.; Lawrence, N.J.; McGown, A.T.; Rennison, D. Potent antimitotic and cell growth inhibitory properties of substituted chalcones. Bioorg. Med. Chem. Lett., 1998, 8, 1051-1056. (Pubitemid 28216282)
-
(1998)
Bioorganic and Medicinal Chemistry Letters
, vol.8
, Issue.9
, pp. 1051-1056
-
-
Ducki, S.1
Forrest, R.2
Hadfield, J.A.3
Kendall, A.4
Lawrence, N.J.5
McGown, A.T.6
Rennison, D.7
-
21
-
-
0033384470
-
Synthesis and biological activity of 4-alkoxy chalcones: Potential hydrophobic modulators of P-glycoprotein-mediated multidrug resistance
-
DOI 10.1016/S0968-0896(99)00218-7, PII S0968089699002187
-
Bois, F.; Boumendjel, A.; Mariotte, A.; Conseil, G.; Di Petro, A. Synthesis and biological activity of 4-alkoxychalcones: potential hydrophobic modulators of P-glycoprotein-mediated multidrug resistance. Bioorg. Med. Chem., 1999, 7, 2691-2695. (Pubitemid 30105841)
-
(1999)
Bioorganic and Medicinal Chemistry
, vol.7
, Issue.12
, pp. 2691-2695
-
-
Bois, F.1
Boumendjel, A.2
Mariotte, A.-M.3
Conseil, G.4
Di Petro, A.5
-
22
-
-
0032724393
-
Bioactivities of chalcones
-
Dimmock, J.R.; Elias, D.W.; Beazely, M.A.; Kandepu, N.M. Bioactivities of chalcones. Curr. Med. Chem., 1999, 6, 1125-1149.
-
(1999)
Curr. Med. Chem.
, vol.6
, pp. 1125-1149
-
-
Dimmock, J.R.1
Elias, D.W.2
Beazely, M.A.3
Kandepu, N.M.4
-
23
-
-
3843137373
-
Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non- small cell lung cancer a549 cells
-
Hsu, Y.L.; Kuo, P.L.; Chiang, L.C.; Lin, C.C. Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non- small cell lung cancer a549 cells. Clin. Exp. Pharmacol. Physiol., 2004, 31, 414-418.
-
(2004)
Clin. Exp. Pharmacol. Physiol.
, vol.31
, pp. 414-418
-
-
Hsu, Y.L.1
Kuo, P.L.2
Chiang, L.C.3
Lin, C.C.4
-
24
-
-
4143140833
-
Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells
-
DOI 10.1016/j.bbrc.2004.07.094, PII S0006291X0401592X
-
Fu, Y.; Hsieh, T.C.; Guo, J.; Kunicki, J.; Lee, M.Y.; Darzynkiewicz, Z.; Wu, J.M. Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells. Biochem. Biophys. Res. Commun., 2004, 322, 263-270. (Pubitemid 39093864)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.322
, Issue.1
, pp. 263-270
-
-
Fu, Y.1
Hsieh, T.-C.2
Guo, J.3
Kunicki, J.4
Lee, M.Y.W.T.5
Darzynkiewicz, Z.6
Wu, J.M.7
-
25
-
-
17144400791
-
Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and tumor growth in mice
-
Zi, X.; Simoneau, A.R. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res., 2005, 65, 3479-3486. (Pubitemid 40524635)
-
(2005)
Cancer Research
, vol.65
, Issue.8
, pp. 3479-3486
-
-
Zi, X.1
Simoneau, A.R.2
-
26
-
-
25644435490
-
Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells
-
DOI 10.1248/bpb.28.1404
-
Tabata, K.; Motani, K.; Takayanagi, N.; Nishimura, R.; Asami, S.; Kimura, Y.; Ukiya, M.; Hasegawa, D.; Akihisa, T.; Suzuki, T. Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells. Biol. Pharm. Bull., 2005, 28, 1404-1407. (Pubitemid 41379689)
-
(2005)
Biological and Pharmaceutical Bulletin
, vol.28
, Issue.8
, pp. 1404-1407
-
-
Tabata, K.1
Motani, K.2
Takayanagi, N.3
Nishimura, R.4
Asami, S.5
Kimura, Y.6
Ukiya, M.7
Hasegawa, D.8
Akihisa, T.9
Suzuki, T.10
-
27
-
-
3042545271
-
2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development
-
DOI 10.1111/j.1349-7006.2004.tb03230.x
-
Takahashi, T.T.; Takasuka, N.; Ligo, M.; Baba, M.; Nishino, H.; Tsuda, H.; Okuyama, T. Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development. Cancer Sci., 2004, 95, 448-453. (Pubitemid 38832690)
-
(2004)
Cancer Science
, vol.95
, Issue.5
, pp. 448-453
-
-
Takahashi, T.1
Takasuka, N.2
Iigo, M.3
Baba, M.4
Nishino, H.5
Tsuda, H.6
Okuyama, T.7
-
28
-
-
25444495234
-
The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts
-
DOI 10.1186/1472-6882-5-5
-
Samoszuk, M.; Tan, J.; Chorn, G. The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts. BMC Complement. Altern. Med., 2005, 5, 5. doi:10.1186/1472-6882-5-5 (Pubitemid 41364089)
-
(2005)
BMC Complementary and Alternative Medicine
, vol.5
, pp. 5
-
-
Samoszuk, M.1
Tan, J.2
Chorn, G.3
-
29
-
-
77954218610
-
Synthesis and anti breast cancer activity of biphenyl based chalcones
-
Sharma, A.; Chakravarti, B.; Gupt, M.P.; Siddiqui, J.A.; Konwar, R.; Tripathi, R.P. Synthesis and anti breast cancer activity of biphenyl based chalcones. Bioorg. Med. Chem., 2010, 18, 4711-4720.
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 4711-4720
-
-
Sharma, A.1
Chakravarti, B.2
Gupt, M.P.3
Siddiqui, J.A.4
Konwar, R.5
Tripathi, R.P.6
-
30
-
-
38049039819
-
Functionalized chalcones as selective inhibitors of P-glycoprotein and breast cancer resistance protein
-
Liu, X-L.; Tee, H.W.; Go, M-L. Functionalized chalcones as selective inhibitors of P-glycoprotein and breast cancer resistance protein. Bioorg. Med. Chem., 2008, 16, 171-180.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 171-180
-
-
Liu, X.-L.1
Tee, H.W.2
Go, M.-L.3
-
31
-
-
75749133254
-
Synthesis cytotoxic evaluation and in silico pharmacokinetic prediction of some benzo[a]phenazine-5-sulfonic acid derivatives
-
Moorthy, N.S.H.N.; Karthikeyan, C.; Trivedi, P. Synthesis, cytotoxic evaluation and in silico pharmacokinetic prediction of some benzo[a]phenazine-5- sulfonic acid derivatives. Med. Chem., 2009, 5, 549-557.
-
(2009)
Med. Chem.
, vol.5
, pp. 549-557
-
-
Moorthy, N.S.H.N.1
Karthikeyan, C.2
Trivedi, P.3
-
32
-
-
77951440482
-
Design synthesis, cytotoxic evaluation and QSAR study of some 6H-indolo[2,3- b]quinoxaline derivatives
-
Moorthy, N.S.H.N.; Karthikeyan, C.; Trivedi, P. Design, synthesis, cytotoxic evaluation and QSAR study of some 6H-indolo[2,3- b]quinoxaline derivatives. J. Enz. Inhibit. Med. Chem., 2010, 25, 394-405.
-
(2010)
J. Enz. Inhibit. Med. Chem.
, vol.25
, pp. 394-405
-
-
Moorthy, N.S.H.N.1
Karthikeyan, C.2
Trivedi, P.3
-
33
-
-
35548958630
-
Improved and rapid synthesis of new coumarinyl chalcone derivatives and their antiviral activity
-
DOI 10.1016/j.tetlet.2007.09.175, PII S0040403907019703
-
Trivedi, J.C.; Bariwal, J.B.; Upadhyay, K.D.; Naliapara, Y.T.; Joshi, S.K.; Pannecouque, C.C.; De Clercq, E.; Shah, A.K. Improved and rapid synthesis of new coumarinyl chalcone derivatives and their antiviral activity. Tetrahedron Lett., 2007, 48, 8472-8474. (Pubitemid 350016206)
-
(2007)
Tetrahedron Letters
, vol.48
, Issue.48
, pp. 8472-8474
-
-
Trivedi, J.C.1
Bariwal, J.B.2
Upadhyay, K.D.3
Naliapara, Y.T.4
Joshi, S.K.5
Pannecouque, C.C.6
De Clercq, E.7
Shah, A.K.8
-
34
-
-
85038508669
-
-
See supplementary information
-
See supplementary information
-
-
-
-
35
-
-
50349093480
-
The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine
-
Hu, C.; Solomon, V.R.; Ulibarri, G.; Lee, H. The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine. Bioorg. Med. Chem., 2008, 16, 7888-7893.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 7888-7893
-
-
Hu, C.1
Solomon, V.R.2
Ulibarri, G.3
Lee, H.4
-
36
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan, P.; Storeng, R.; Scudiero, D.; Monks, A.; McMahon, J.; Vistica, D.; Warren, J. T.; Bokesch, H.; Kenney, S.; Boyd, M. R. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst., 1990, 82, 1107-1112. (Pubitemid 20213250)
-
(1990)
Journal of the National Cancer Institute
, vol.82
, Issue.13
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
|