Synthesis and antiproliferative activity in vitro of novel (2-butynyl)thioquinolines

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 17, 2008, Pages 8136-8141

  Mol W ^a   Matyja, M ^a   Filip, B ^b   Wietrzyk, J ^b   Boryczka, S ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

^b INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

Author keywords

(2 Butynyl)thioquinolines; Acetylenic thioquinolines; Antiproliferative activity

Indexed keywords

(2 BUTYNYL)THIOQUINOLINE DERIVATIVE; 4 (4 BROMO 2 BUTYNYLSELENO) 3 (4 HYDROXY 2 BUTYNYLTHIO)QUINOLINE; 4 (4 BROMO 2 BUTYNYLSELENO) 3 (PROPARGYLTHIO)QUINOLINE; 4 (4 HYDROXY 2 BUTYNYLSELENO) 3 (PROPARGYLTHIO)QUINOLINE; 4 (4 HYDROXY 2 BUTYNYLSELENO) 3 METHYLTHIOQUINOLINE; ACETYLENE DERIVATIVE; CISPLATIN; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LEUKEMIA, EXPERIMENTAL; MELANOMA, EXPERIMENTAL; MICE; MOLECULAR STRUCTURE; QUINOLINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFIDES;

MURINAE;

EID: 50349088132     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.07.047     Document Type: Article

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