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Volumn 377, Issue 4-6, 2008, Pages 411-421

A selective T-type Ca2+ channel blocker R(-) efonidipine

Author keywords

Ca2+ channels; Hippocampal CA1 neuron; R( ) efonidipine; T type

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; EFONIDIPINE; FLUNARIZINE; MIBEFRADIL; NYSTATIN; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

EID: 45849109532     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-007-0239-6     Document Type: Conference Paper
Times cited : (17)

References (49)
  • 1
    • 45849096595 scopus 로고    scopus 로고
    • Heterogeneous distribution of LVA and HVA calcium channels in mammalian brain tissue
    • Adis International Chester
    • Akaike N (1996) Heterogeneous distribution of LVA and HVA calcium channels in mammalian brain tissue. In: Tsien RW, Clozel JP, Nargeot J (eds) Low-Voltage-Activated T-type Calcium Channels, Adis International, Chester, pp 53-62
    • (1996) Low-Voltage-Activated T-type Calcium Channels , pp. 53-62
    • Akaike, N.1    Tsien, R.W.2    Clozel, J.P.3    Nargeot, J.4
  • 2
    • 0028555787 scopus 로고
    • Nystatin perforated patch recording and its applications to analyses of intracellular mechanisms
    • Akaike N, Harata N (1994) Nystatin perforated patch recording and its applications to analyses of intracellular mechanisms. Jpn J Physiol 44:433-473
    • (1994) Jpn J Physiol , vol.44 , pp. 433-473
    • Akaike, N.1    Harata, N.2
  • 3
    • 0026633494 scopus 로고
    • Tetrodotoxin-sensitive calcium-conducting channels in the rat hippocampal CA1 region
    • Akaike N, Takahashi K (1992) Tetrodotoxin-sensitive calcium-conducting channels in the rat hippocampal CA1 region. J Physiol 450:529-546
    • (1992) J Physiol , vol.450 , pp. 529-546
    • Akaike, N.1    Takahashi, K.2
  • 4
    • 0024465188 scopus 로고
    • Low-voltage-activated calcium current in rat aorta smooth muscle cells in primary culture
    • Akaike N, Kanaide H, Kuga T, Nakamura M, Sadoshima J, Tomoike H (1989a) Low-voltage-activated calcium current in rat aorta smooth muscle cells in primary culture. J Physiol 416:141-160
    • (1989) J Physiol , vol.416 , pp. 141-160
    • Akaike, N.1    Kanaide, H.2    Kuga, T.3    Nakamura, M.4    Sadoshima, J.5    Tomoike, H.6
  • 5
    • 0024335298 scopus 로고
    • Dihydropyridine-sensitive low-threshold calcium channels in isolated rat hypothalamic neurones
    • Akaike N, Kostyuk PG, Osipchuk YV (1989b) Dihydropyridine-sensitive low-threshold calcium channels in isolated rat hypothalamic neurones. J Physiol 412:181-195
    • (1989) J Physiol , vol.412 , pp. 181-195
    • Akaike, N.1    Kostyuk, P.G.2    Osipchuk, Y.V.3
  • 6
    • 0025923603 scopus 로고
    • Heterogeneous distribution of tetrodotoxin-sensitive calcium-conducting channels in rat hippocampal CA1 neurons
    • Akaike N, Takahashi K, Morimoto M (1991) Heterogeneous distribution of tetrodotoxin-sensitive calcium-conducting channels in rat hippocampal CA1 neurons. Brain Res 556:135-138
    • (1991) Brain Res , vol.556 , pp. 135-138
    • Akaike, N.1    Takahashi, K.2    Morimoto, M.3
  • 7
    • 0023905674 scopus 로고
    • Comparative protective effects of nicardipine, flunarizine, lidoflazine and nimodipine against ischaemic injury in the hippocampus of the Mongolian gerbil
    • Alps BJ, Calder C, Hass WK, Wilson AD (1988) Comparative protective effects of nicardipine, flunarizine, lidoflazine and nimodipine against ischaemic injury in the hippocampus of the Mongolian gerbil. Br J Pharmacol 93:877-883
    • (1988) Br J Pharmacol , vol.93 , pp. 877-883
    • Alps, B.J.1    Calder, C.2    Hass, W.K.3    Wilson, A.D.4
  • 8
    • 0018976265 scopus 로고
    • Cerebral protective, metabolic, and vascular effects of phenytoin
    • Artru AA, Michenfelder JD (1980) Cerebral protective, metabolic, and vascular effects of phenytoin. Stroke 11:377-382
    • (1980) Stroke , vol.11 , pp. 377-382
    • Artru, A.A.1    Michenfelder, J.D.2
  • 9
    • 29844439240 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels
    • Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J (2005) International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol Rev 57:411-425
    • (2005) Pharmacol Rev , vol.57 , pp. 411-425
    • Catterall, W.A.1    Perez-Reyes, E.2    Snutch, T.P.3    Striessnig, J.4
  • 10
    • 0023753142 scopus 로고
    • Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage
    • Choi DW (1988) Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci 11:465-469
    • (1988) Trends Neurosci , vol.11 , pp. 465-469
    • Choi, D.W.1
  • 13
    • 0031282933 scopus 로고    scopus 로고
    • T-type Ca2+ channels and pharmacological blockade: Potential pathophysiological relevance
    • Ertel SI, Ertel EA, Clozel JP (1997) T-type Ca2+ channels and pharmacological blockade: potential pathophysiological relevance. Cardiovasc Drugs Ther 11:723-739
    • (1997) Cardiovasc Drugs Ther , vol.11 , pp. 723-739
    • Ertel, S.I.1    Ertel, E.A.2    Clozel, J.P.3
  • 16
    • 0033962172 scopus 로고    scopus 로고
    • Effect of mibefradil on voltage-dependent gating and kinetics of T-type Ca(2+) channels in cortisol-secreting cells
    • Gomora JC, Xu L, Enyeart JA, Enyeart JJ (2000) Effect of mibefradil on voltage-dependent gating and kinetics of T-type Ca(2+) channels in cortisol-secreting cells. J Pharmacol Exp Ther 292:96-103
    • (2000) J Pharmacol Exp Ther , vol.292 , pp. 96-103
    • Gomora, J.C.1    Xu, L.2    Enyeart, J.A.3    Enyeart, J.J.4
  • 17
    • 0023245038 scopus 로고
    • Ethanol-induced component of 45Ca2+ uptake in PC12 cells is sensitive to Ca2+ channel modulating drugs
    • Greenberg DA, Carpenter CL, Messing RO (1987) Ethanol-induced component of 45Ca2+ uptake in PC12 cells is sensitive to Ca2+ channel modulating drugs. Brain Res 410:143-146
    • (1987) Brain Res , vol.410 , pp. 143-146
    • Greenberg, D.A.1    Carpenter, C.L.2    Messing, R.O.3
  • 18
    • 0030663243 scopus 로고    scopus 로고
    • Physiologic and pathophysiologic relevance of T-type calcium-ion channels: Potential indications for T-type calcium antagonists
    • Suppl A
    • Hermsmeyer K, Mishra S, Miyagawa K, Minshall R (1997) Physiologic and pathophysiologic relevance of T-type calcium-ion channels: potential indications for T-type calcium antagonists. Clin Ther 19(Suppl A):18-26
    • (1997) Clin Ther , vol.19 , pp. 18-26
    • Hermsmeyer, K.1    Mishra, S.2    Miyagawa, K.3    Minshall, R.4
  • 19
    • 0023795593 scopus 로고
    • Muscarinic activation of ionic currents measured by a new whole-cell recording method
    • Horn R, Marty A (1988) Muscarinic activation of ionic currents measured by a new whole-cell recording method. J Gen Physiol 92:145-159
    • (1988) J Gen Physiol , vol.92 , pp. 145-159
    • Horn, R.1    Marty, A.2
  • 20
    • 0029066292 scopus 로고
    • Somatostatin modulates high-voltage-activated Ca channels in freshly dissociated rat hippocampal neurons
    • Ishibashi H, Akaike N (1995) Somatostatin modulates high-voltage- activated Ca channels in freshly dissociated rat hippocampal neurons. J Neurophysiol 74:1028-1036
    • (1995) J Neurophysiol , vol.74 , pp. 1028-1036
    • Ishibashi, H.1    Akaike, N.2
  • 21
    • 0029119272 scopus 로고
    • Regional difference of high voltage-activated Ca2+ channels in rat CNS neurones
    • Ishibashi H, Rhee JS, Akaike N (1995) Regional difference of high voltage-activated Ca2+ channels in rat CNS neurones. Neuroreport 6:1621-1624
    • (1995) Neuroreport , vol.6 , pp. 1621-1624
    • Ishibashi, H.1    Rhee, J.S.2    Akaike, N.3
  • 23
    • 0022479032 scopus 로고
    • NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones
    • MacDermott AB, Mayer ML, Westbrook GL, Smith SJ, Barker JL (1986) NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones. Nature 321:519-522
    • (1986) Nature , vol.321 , pp. 519-522
    • MacDermott, A.B.1    Mayer, M.L.2    Westbrook, G.L.3    Smith, S.J.4    Barker, J.L.5
  • 24
    • 0032454849 scopus 로고    scopus 로고
    • The role of excitotoxicity and metabolic failure in the pathogenesis of neurological disorders
    • Massieu L, Garcia O (1998) The role of excitotoxicity and metabolic failure in the pathogenesis of neurological disorders. Neurobiology (Bp) 6:99-108
    • (1998) Neurobiology (Bp) , vol.6 , pp. 99-108
    • Massieu, L.1    Garcia, O.2
  • 26
    • 0032557472 scopus 로고    scopus 로고
    • Inhibition of myocardial L- and T-type Ca2+ currents by efonidipine: Possible mechanism for its chronotropic effect
    • Masumiya H, Shijuku T, Tanaka H, Shigenobu K (1998) Inhibition of myocardial L- and T-type Ca2+ currents by efonidipine: possible mechanism for its chronotropic effect. Eur J Pharmacol 349:351-357
    • (1998) Eur J Pharmacol , vol.349 , pp. 351-357
    • Masumiya, H.1    Shijuku, T.2    Tanaka, H.3    Shigenobu, K.4
  • 27
    • 0032407483 scopus 로고    scopus 로고
    • Mibefradil inhibition of T-type calcium channels in cerebellar Purkinje neurons
    • McDonough SI, Bean BP (1998) Mibefradil inhibition of T-type calcium channels in cerebellar Purkinje neurons. Mol Pharmacol 54:1080-1087
    • (1998) Mol Pharmacol , vol.54 , pp. 1080-1087
    • McDonough, S.I.1    Bean, B.P.2
  • 28
    • 0026763873 scopus 로고
    • P-type calcium channels in rat central and peripheral neurons
    • Mintz IM, Adams ME, Bean BP (1992) P-type calcium channels in rat central and peripheral neurons. Neuron 9:85-95
    • (1992) Neuron , vol.9 , pp. 85-95
    • Mintz, I.M.1    Adams, M.E.2    Bean, B.P.3
  • 29
    • 22344454398 scopus 로고    scopus 로고
    • Inhibition of T-type calcium channels protects neurons from delayed ischemia-induced damage
    • Nikonenko I, Bancila M, Bloc A, Muller D, Bijlenga P (2005) Inhibition of T-type calcium channels protects neurons from delayed ischemia-induced damage. Mol Pharmacol 68:84-89
    • (2005) Mol Pharmacol , vol.68 , pp. 84-89
    • Nikonenko, I.1    Bancila, M.2    Bloc, A.3    Muller, D.4    Bijlenga, P.5
  • 30
    • 0001493110 scopus 로고    scopus 로고
    • Pharmacological properties of the human cardiac cloned T-type calcium channel
    • Ono K, Lee TS, Kaku T, Arita M (2000) Pharmacological properties of the human cardiac cloned T-type calcium channel. Jpn J Electrocardiol 20:109-112
    • (2000) Jpn J Electrocardiol , vol.20 , pp. 109-112
    • Ono, K.1    Lee, T.S.2    Kaku, T.3    Arita, M.4
  • 31
    • 0034038723 scopus 로고    scopus 로고
    • Pharmacological properties of Ca(V)3.2, a low voltage-activated Ca2+ channel cloned from human heart
    • Perchenet L, Benardeau A, Ertel EA (2000) Pharmacological properties of Ca(V)3.2, a low voltage-activated Ca2+ channel cloned from human heart. Naunyn Schmiedebergs Arch Pharmacol 361:590-599
    • (2000) Naunyn Schmiedebergs Arch Pharmacol , vol.361 , pp. 590-599
    • Perchenet, L.1    Benardeau, A.2    Ertel, E.A.3
  • 32
    • 0032754628 scopus 로고    scopus 로고
    • Three for T: Molecular analysis of the low voltage-activated calcium channel family
    • 7-8
    • Perez-Reyes E (1999) Three for T: molecular analysis of the low voltage-activated calcium channel family. Cell Mol Life Sci 15;56(7-8):660-669
    • (1999) Cell Mol Life Sci 15 , vol.56 , pp. 660-669
    • Perez-Reyes, E.1
  • 34
    • 0028904492 scopus 로고
    • Pharmacological dissection of multiple types of Ca2+ channel currents in rat cerebellar granule neurons
    • Randall A, Tsien RW (1995) Pharmacological dissection of multiple types of Ca2+ channel currents in rat cerebellar granule neurons. J Neurosci 15:2995-3012
    • (1995) J Neurosci , vol.15 , pp. 2995-3012
    • Randall, A.1    Tsien, R.W.2
  • 35
    • 0026738501 scopus 로고
    • Synthesis of 1,4-dihydropyridine-5-phosphonates and their calcium-antagonistic and antihypertensive activities: Novel calcium-antagonist 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl) -1,4-dihydro-2,6-dim ethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate hydrochloride ethanol (NZ-105) and its crystal structure
    • Sakoda R, Kamikawaji Y, Seto K (1992) Synthesis of 1,4-dihydropyridine-5- phosphonates and their calcium-antagonistic and antihypertensive activities: novel calcium-antagonist 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3, 2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dim ethyl-4-(3-nitrophenyl)-3- pyridinecarboxylate hydrochloride ethanol (NZ-105) and its crystal structure. Chem Pharm Bull (Tokyo) 40:2362-2369
    • (1992) Chem Pharm Bull (Tokyo) , vol.40 , pp. 2362-2369
    • Sakoda, R.1    Kamikawaji, Y.2    Seto, K.3
  • 37
    • 0025965184 scopus 로고
    • Calcium antagonist effects on low-threshold (T-type) calcium current in rat isolated hippocampal CA1 pyramidal neurons
    • Takahashi K, Akaike N (1991) Calcium antagonist effects on low-threshold (T-type) calcium current in rat isolated hippocampal CA1 pyramidal neurons. J Pharmacol Exp Therap 256:169-175
    • (1991) J Pharmacol Exp Therap , vol.256 , pp. 169-175
    • Takahashi, K.1    Akaike, N.2
  • 38
    • 0024325834 scopus 로고
    • Hippocampal CA1 pyramidal cells of rats have four voltage-dependent calcium conductances
    • Takahashi K, Wakamori M, Akaike N (1989) Hippocampal CA1 pyramidal cells of rats have four voltage-dependent calcium conductances. Neurosci Lett 104:229-234
    • (1989) Neurosci Lett , vol.104 , pp. 229-234
    • Takahashi, K.1    Wakamori, M.2    Akaike, N.3
  • 39
    • 28044471562 scopus 로고    scopus 로고
    • Pathophysiological significance of T-type Ca2+ channels: T-type Ca2+ channels and drug development
    • Tanaka H, Shigenobu K (2005) Pathophysiological significance of T-type Ca2+ channels: T-type Ca2+ channels and drug development. J Pharmacol Sci 99:214-220
    • (2005) J Pharmacol Sci , vol.99 , pp. 214-220
    • Tanaka, H.1    Shigenobu, K.2
  • 40
    • 12444311717 scopus 로고    scopus 로고
    • The R(-)-enantiomer of efonidipine blocks T-type but not L-type calcium current in guinea pig ventricular myocardium
    • Tanaka H, Komikado C, Shimada H, Takeda K, Namekata I, Kawanishi T, Shigenobu K (2004) The R(-)-enantiomer of efonidipine blocks T-type but not L-type calcium current in guinea pig ventricular myocardium. J Pharmacol Sci 96:499-501
    • (2004) J Pharmacol Sci , vol.96 , pp. 499-501
    • Tanaka, H.1    Komikado, C.2    Shimada, H.3    Takeda, K.4    Namekata, I.5    Kawanishi, T.6    Shigenobu, K.7
  • 41
    • 0023144605 scopus 로고
    • Actions of flunarizine, a Ca++ antagonist, on ionic currents in fragmented smooth muscle cells of the rabbit small intestine
    • Terada K, Ohya Y, Kitamura K, Kuriyama H (1987) Actions of flunarizine, a Ca++ antagonist, on ionic currents in fragmented smooth muscle cells of the rabbit small intestine. J Pharmacol Exp Ther 240:978-983
    • (1987) J Pharmacol Exp Ther , vol.240 , pp. 978-983
    • Terada, K.1    Ohya, Y.2    Kitamura, K.3    Kuriyama, H.4
  • 42
    • 0023904846 scopus 로고
    • The T-type Ca channel in guinea-pig ventricular myocytes is insensitive to isoproterenol
    • Tytgat J, Nilius B, Vereecke J, Carmeliet E (1988a) The T-type Ca channel in guinea-pig ventricular myocytes is insensitive to isoproterenol. Pflugers Arch 411:704-706
    • (1988) Pflugers Arch , vol.411 , pp. 704-706
    • Tytgat, J.1    Nilius, B.2    Vereecke, J.3    Carmeliet, E.4
  • 43
    • 0023680501 scopus 로고
    • Differential effects of verapamil and flunarizine on cardiac L-type and T-type Ca channels
    • Tytgat J, Vereecke J, Carmeliet E (1988b) Differential effects of verapamil and flunarizine on cardiac L-type and T-type Ca channels. Naunyn Schmiedebergs Arch Pharmacol 337:690-692
    • (1988) Naunyn Schmiedebergs Arch Pharmacol , vol.337 , pp. 690-692
    • Tytgat, J.1    Vereecke, J.2    Carmeliet, E.3
  • 44
    • 0027442001 scopus 로고
    • Cytoplasmic pH regulates ATP-induced Ca(2+)-dependent K(+)-current oscillation in rat megakaryocytes
    • Pt 1
    • Uneyama C, Uneyama H, Takahashi M, Akaike N (1993) Cytoplasmic pH regulates ATP-induced Ca(2+)-dependent K(+)-current oscillation in rat megakaryocytes. Biochem J 295(Pt 1):317-320
    • (1993) Biochem J , vol.295 , pp. 317-320
    • Uneyama, C.1    Uneyama, H.2    Takahashi, M.3    Akaike, N.4
  • 45
    • 0032791883 scopus 로고    scopus 로고
    • T-channel-selective calcium channel blockade: A promising therapeutic possibility, only preliminarily tested so far: A review of published data. T-Channel Calcium Channel Blocker Study Group
    • Van der Vring JA, Cleophas TJ, Van der Wall EE, Niemeyer MG (1999) T-channel-selective calcium channel blockade: a promising therapeutic possibility, only preliminarily tested so far: a review of published data. T-Channel Calcium Channel Blocker Study Group. Am J Ther 6:229-233
    • (1999) Am J Ther , vol.6 , pp. 229-233
    • Van Der Vring, J.A.1    Cleophas, T.J.2    Van Der Wall, E.E.3    Niemeyer, M.G.4
  • 46
    • 0030685757 scopus 로고    scopus 로고
    • Mibefradil (Ro 40-5967) blocks multiple types of voltage-gated calcium channels in cultured rat spinal motoneurones
    • Viana F, Van den BL, Missiaen L, Vandenberghe W, Droogmans G, Nilius B, Robberecht W (1997) Mibefradil (Ro 40-5967) blocks multiple types of voltage-gated calcium channels in cultured rat spinal motoneurones. Cell Calcium 22:299-311
    • (1997) Cell Calcium , vol.22 , pp. 299-311
    • Viana, F.1    Van Den, B.L.2    Missiaen, L.3    Vandenberghe, W.4    Droogmans, G.5    Nilius, B.6    Robberecht, W.7
  • 47
    • 0023123383 scopus 로고
    • Development of two types of calcium channels in cultured mammalian hippocampal neurons
    • Yaari Y, Hamon B, Lux HD (1987) Development of two types of calcium channels in cultured mammalian hippocampal neurons. Science 235:680-682
    • (1987) Science , vol.235 , pp. 680-682
    • Yaari, Y.1    Hamon, B.2    Lux, H.D.3
  • 48
    • 0029845429 scopus 로고    scopus 로고
    • Effects of efonidipine hydrochloride, a calcium antagonist derived from dihydropyridine, on acute myocardial ischemia in anesthetized open-chest dogs
    • Yokoyama T, Fujikura N, Masuda Y, Shikada K, Tanaka S (1996) Effects of efonidipine hydrochloride, a calcium antagonist derived from dihydropyridine, on acute myocardial ischemia in anesthetized open-chest dogs. Nippon Yakurigaku Zasshi 108:307-321
    • (1996) Nippon Yakurigaku Zasshi , vol.108 , pp. 307-321
    • Yokoyama, T.1    Fujikura, N.2    Masuda, Y.3    Shikada, K.4    Tanaka, S.5
  • 49
    • 0030784933 scopus 로고    scopus 로고
    • Neuroprotection by the novel calcium antagonist PCA50938, nimodipine and flunarizine, in gerbil global brain ischemia
    • Zapater P, Moreno J, Horga JF (1997) Neuroprotection by the novel calcium antagonist PCA50938, nimodipine and flunarizine, in gerbil global brain ischemia. Brain Res 772:57-62
    • (1997) Brain Res , vol.772 , pp. 57-62
    • Zapater, P.1    Moreno, J.2    Horga, J.F.3


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