Role of T-type calcium current in identified D-hair mechanoreceptor neurons studied in vitro

Journal of Neuroscience

Volumn 24, Issue 39, 2004, Pages 8480-8484

  Dubreuil, Anne Sophie ^a   Boukhaddaoui, Hassan ^a   Desmadryl, Gilles ^a   Martinez Salgado, Carlos ^b,d   Moshourab, Rabih ^b   Lewin, Gary R ^b   Carroll, Patrick ^a   Valmier, Jean ^a   Scamps, Frédérique ^a,c  

^a HÔPITAL SAINT ELOI   (France)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c Montpellier University Medical Center   (France)

^d HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

Cav3.2; D hair neuron; Dorsal root ganglion; Mechanotransduction; Neurotrophin; T type calcium channel

Indexed keywords

CALCIUM CHANNEL T TYPE; NEUROTROPHIN 4; VOLTAGE GATED CALCIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL STRUCTURE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; IN VITRO STUDY; KNOCKOUT MOUSE; MECHANORECEPTOR; MECHANOTRANSDUCTION; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; ROSETTE FORMATION; SPIKE WAVE; SPINAL GANGLION;

ACTION POTENTIALS; AGING; ANIMALS; CALCIUM CHANNELS, T-TYPE; CELL ENLARGEMENT; CELL SHAPE; CELLS, CULTURED; FEMALE; GANGLIA, SPINAL; MECHANORECEPTORS; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; NERVE GROWTH FACTORS; NEURONS; NICKEL; PATCH-CLAMP TECHNIQUES;

EID: 4744374730     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1598-04.2004     Document Type: Article

References (18)

1. Adriaensen H, Gybels J, Handwerker HO, Van Hees J (1983) Response properties of thin myelinated (A-delta) fibers in human skin nerves. J Neurophysiol 49:111-122.
2. Andre S, Boukhaddaoui H, Campo B, Al-Jumaily M, Mayeux V, Greuet D, Valmier J, Scamps F (2003) Axotomy-induced expression of calcium-activated chloride current in subpopulations of mouse dorsal root ganglion neurons. J Neurophysiol 90:3764-3773.
3. Baccaglini PI, Hogan PG (1983) Some rat sensory neurons in culture express characteristics of differentiated pain sensory cells. Proc Natl Acad Sci USA 80:594-598.
4. Bossu JL, Feltz A, Thomann JM (1985) Depolarization elicits two distinct calcium currents in vertebrate sensory neurones. Pflügers Arch 403:360-368.
5. Brown AG, Iggo A (1967) A quantitative study of cutaneous receptors and afferent fibres in the cat and rabbit. J Physiol (Lond) 193:707-733.
6. Cesare P, Mcnaughton P (1997) Peripheral pain mechanisms. Curr Opin Neurobiol 7:493-499.
7. Desmadryl G, Hilaire C, Vigues S, Diochot S, Valmier J (1998) Developmental regulation of T-, N- and L-type calcium currents in mouse embryonic sensory neurones. Eur J Neurosci 10:545-552.
8. Djouhri L, Bleazard L, Lawson SN (1998) Association of somatic action potential shape with sensory receptive properties in guinea-pig dorsal root ganglion neurones. J Physiol (Lond) 513:857-872.
9. Koltzenburg M, Stucky CL, Lewin GR (1997) Receptive properties of mouse sensory neurons innervating hairy skin. J Neurophysiol 78:1841-1850.
10. Lee JH, Gomora JC, Cribbs LL, Perez-Reyes E (1999) Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H. Biophys J 77:3034-3042.
11. Lewin GR, Ritter AM, Mendell LM (1992) On the role of nerve growth factor in the development of myelinated nociceptors. J Neurosci 12:1896-1905.
12. Lindsay RM (1988) Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons. J Neurosci 8:2394-2405.
13. Perez-Reyes E (1999) Three for T: molecular analysis of the low voltage-activated calcium channel family. Cell Mol Life Sci 56:660-669.
14. Ritter AM, Mendell LM (1992) Somal membrane properties of physiologically identified sensory neurons in the rat: effects of nerve growth factor. J Neurophysiol 68:2033-2041.
15. Schroeder JE, Fischbach PS, McCleskey EW (1990) T-type calcium channels: heterogeneous expression in rat sensory neurons and selective modulation by phorbol esters. J Neurosci 10:947-951.
16. Scroggs RS, Fox AP (1992) Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size. J Physiol (Lond) 445:639-658.
17. Shin J-B, Martinez-Salgado C, Heppenstall PA, Lewin GR (2003) A T-type calcium channel required for normal function of a mammalian mechanoreceptor. Nat Neurosci 6:724-730.
18. Stucky CL, Shin JB, Lewin GR (2002) Neurotrophin-4: a survival factor for adult sensory neurons. Curr Biol 12:1401-1404.