Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking α1G T-type Ca2+ channels

Neuron

Volumn 31, Issue 1, 2001, Pages 35-45

  Kim, Daesoo ^a   Song, Inseon ^a   Keum, Sehoon ^a   Lee, Taehoon ^a   Jeong, Myung Jin ^a   Kim, Sung Sook ^a   McEnery, Maureen W ^b   Shin, Hee Sup ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; CALCIUM CHANNEL T TYPE; CALCIUM ION; MUTANT PROTEIN; PROTEIN SUBUNIT;

ABSENCE; ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; DISEASE RESISTANCE; EPILEPTOGENESIS; FEMALE; GENE MUTATION; INTERNEURON; KNOCKOUT MOUSE; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; SPIKE; SPIKE WAVE; THALAMOCORTICAL TRACT; THALAMUS;

EID: 0034879821     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(01)00343-9     Document Type: Article

References (47)

1. Roles of gamma-aminobutyric acidB (GABA B) and gamma-hydroxybutyric acid receptors in hippocampal long-term potentiation and pathogenesis of absence seizures
2. GABA-mediated synchronous potentials and seizure generation
3. The effects of tbansient functional depression of the thalamus on spindles and on bilateral synchronous epileptic discharges of feline generalized penicillin epilepsy
4. Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami
5. Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons
6. A role for GABAB receptors in excitation and inhibition of thalamocortical cells
7. Electrophysiology of neurons of lateral thalamic nuclei in cat: Resting properties and burst discharges
8. Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices
9. GABAA receptor function in developing rat thalamic reticular neurons: Whole cell recordings of GABA-mediated currents and modulation by clonazepam
10. Generalized epilepsy: Some of its cellular mechanisms differ from those of focal epilepsy
11. Receiver operating characteristic (ROC) analysis of neurons in the cat's lateral geniculate nucleus during tonic and burst response mode
12. The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice
13. B-mediated inhibition in thalamic relay neurons through effects in nucleus reticularis
14. Intrathalamic rhythmicity studied in vitro: Nominal T-current modulation causes robust antioscillatory effects
15. Reciprocal inhibitory connections and network cynchrony in the mammalian thalamus
16. Thalamic multiple-unit activity underlying spike-wave discharges in anesthetized rats
17. Ionic basis for the electro-responsiveness and oscillatory properties of guinea-pig thalamic neurones in vitro
18. Phospholipase C isozymes selectively couple to specific neurotransmitter receptors
19. Different action of ethosuximide on low- and high-threshold calcium currents in rat sensory neurons
20. On the action of the anti-absence drug ethosuximide in the rat and cat thalamus
21. B receptors in the lethargic (lh/lh) mouse model of absence epilepsy
22. Intracellular and extracellular in vivo recording of different response modes for relay cells of the cat's lateral geniculate nucleus
23. Lateral geniculate nucleus unitary discharge in sleep and waking: State- and bate-specific aspects
24. Sensory gating mechanisms of the thalamus
25. Functional implications of burst firing and single spike activity in lateral geniculate relay neurons
26. Beta1B subunit of voltage-dependent Ca2+ channels is predominant isoform expressed in human neuroblastoma cell line IMR32
27. REM sleep burst neurons, PGO waves, and eye movement information
28. Primary (idiopathic) generalized epilepsy and underlying mechanisms
29. Role of afferent input of subcortical origin in the genesis of bilaterally synchronous epileptic discharges of feline generalized penicillin epilepsy
30. Molecular characterization of a neuronal low-voltage-activated T type calcium channel
31. Molecular characterization of a neuronal low-voltage-activated T type calcium channel
32. Intracellular recordings in thalamic neurones during spontaneous spike and wave discharges in rats widh absence epilepsy
33. Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons
34. Dual response modes in lateral geniculate neurons: Mechanisms and functions
35. The selective GABAB antagonist CGP-35348 blocks spike-wave bursts in the cholesterol synthesis rat absence epilepsi model
36. Modulation of absence seizures by the GABA(A) receptor: A critical rolefor metabotropic glutamate receptor 4 (mGluR4)
37. gamma-Hydroxybutyrate model of generalized absence seizures: Further characterization and comparison with other absence models
38. Evidence for GABAB-mediated mechanisms in experimental generalized absence seizures
39. Thalamocortical oscillations in the sleeping and aroused brain
40. Relations between cortical and thalamic cellular events during transition from sleep patterns to paroxysmal actividy
41. Spike-wave complexes and fast components of cortically generated seizures. I. Role of neocortex and thalamus
42. Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels
43. Low-voltage-activated calcium channel subunit expression in a genetic model of absence epilepsy in the rat
44. Selective increase in T-type calcium conductance of reticular thalamic neurons in a rat model of absence epilepsy
45. Differential expression and association of calcium channel alpha1B and beta subunits during rat brain ontogeny
46. A study of thalamic and cortical rhythms in petit mal