Lentiviral shRNA silencing of CHOP inhibits apoptosis induced by cyclic stretch in rat annular cells and attenuates disc degeneration in the rats

Apoptosis

Volumn 16, Issue 6, 2011, Pages 594-605

  Zhang, Yue Hui ^a   Zhao, Chang Qing ^a   Jiang, Lei Sheng ^a   Dai, Li Yang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Apoptosis; Cyclic stretch; Endoplasmic reticulum; Intervertebral disc degeneration; Lentivirus; RNA interference

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; LENTIVIRUS VECTOR; MESSENGER RNA; SHORT HAIRPIN RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANNULUS FIBROSUS; APOPTOSIS; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LUMBAR SPINE; NICK END LABELING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINE RADIOGRAPHY; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BIOMECHANICS; CELLS, CULTURED; DOWN-REGULATION; FEMALE; GENE SILENCING; GENE THERAPY; GENETIC VECTORS; HUMANS; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LENTIVIRUS; RATS; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR CHOP;

LENTIVIRUS; RATTUS;

EID: 79955867187     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0596-y     Document Type: Article

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