ISSLS prize winner: LMP-1 upregulates intervertebral disc cell production of proteoglycans and BMPs in vitro and in vivo

Spine

Volumn 29, Issue 23, 2004, Pages 2603-2611

  Yoon, Sangwook Tim ^a,b,e   Park, Jin Soo ^c   Kim, Keun S ^d   Li, Jun ^a,b   Attallah Wasif, Emad Samir ^a,b   Hutton, William C ^a,b   Boden, Scott D ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ATLANTA VA MEDICAL CENTER   (United States)

^c KURUME UNIVERSITY   (Japan)

^d Yonsei University College of Medicine   (South Korea)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BMP; Gene therapy; Intervertebral disc; LMP 1; Proteoglycans

Indexed keywords

ADENOVIRUS VECTOR; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; GLYCOSAMINOGLYCAN POLYSULFATE; LIM MINERALIZATION PROTEIN 1; LIM PROTEIN; MESSENGER RNA; NOGGIN; OSTEOGENIC PROTEIN 1; PROTEOGLYCAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE THERAPY; INTERVERTEBRAL DISK; LUMBAR SPINE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOVIRIDAE; AGGRECANS; ANIMALS; AWARDS AND PRIZES; BONE MORPHOGENETIC PROTEINS; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; GENETIC VECTORS; GLYCOSAMINOGLYCANS; HUMANS; INTERVERTEBRAL DISK; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; ORTHOPEDICS; PROTEOGLYCANS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 14844338710     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.brs.0000146103.94600.85     Document Type: Article

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