Stochastic ensembles, conformationally adaptive teamwork, and enzymatic detoxification

Biochemistry

Volumn 50, Issue 19, 2011, Pages 3866-3872

  Atkins, William M ^a   Qian, Hong ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX SURFACE; CONFORMATIONAL DYNAMICS; CONFORMATIONAL ENSEMBLE; CONFORMATIONAL HETEROGENEITY; DETOXIFICATION ENZYMES; ENERGY LANDSCAPE; ENZYME FUNCTIONS; EXPERIMENTAL EVIDENCE; FOLDED PROTEINS; IMMUNE SYSTEMS; KINETIC SIMULATION; MULTIFUNCTIONALITY; MULTIPLE DIMENSIONS; MULTIPLE PRODUCTS; MULTIPLE SUBSTRATES; MULTIPLE TIME SCALE; NONEQUILIBRIUM STEADY STATE; PRODUCT FORMATION; TIME-DEPENDENT; TRANSITION STATE;

BEHAVIORAL RESEARCH; BIOLOGY; CATALYSTS; ENZYMES; FUNCTIONAL POLYMERS; LAKES; SCAFFOLDS (BIOLOGY); SIGNAL TRANSDUCTION; SUBSTRATES; SURFACE TOPOGRAPHY;

DETOXIFICATION;

ENZYME;

ARTICLE; CATALYSIS; DETOXIFICATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME SUBSTRATE; PLASTICITY; PRIORITY JOURNAL; STEADY STATE; STOCHASTIC MODEL;

BIOLOGICAL TRANSPORT, ACTIVE; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; GLUCURONOSYLTRANSFERASE; LIGANDS; METABOLIC DETOXICATION, DRUG; MODELS, CHEMICAL; P-GLYCOPROTEIN; PROTEIN CONFORMATION; STOCHASTIC PROCESSES; SUBSTRATE SPECIFICITY;

EID: 79955831096     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200275r     Document Type: Article

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